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Childhood Fructoholism and Fructoholic Liver Disease : Hepatology Communications

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Ribeiro, Andreia Igual-Perez, Maria-Jose Santos Silva, Ermelinda Sokal, Etienne [UCL]

Nonalcoholic fatty liver disease (NAFLD) is an emerging entity, becoming the most prevalent pediatric chronic liver disease. Its broad spectrum of histological findings, comorbidities, and complications, including cirrhosis and liver failure, can occur in childhood, emphasizing the severity of pediatric NAFLD. Current lifestyle and diet modifications have been linked to the increasing prevalence of NAFLD, including the rise of fructose consumption, a monosaccharide present in foods that contain added sugar, such as sugar-sweetened beverages. Excessive fructose consumption is believed to cause addiction like alcohol and other drugs. As such, the new term "fructoholism" refers to the consumption of a substance (fructose) that can cause psychological and physical damage and become a major public health concern, highlighting the seriousness of the excessive consumption of fructose in the pediatric age. Hepatic fructose metabolization leads to hepatic steatosis and progression to fibrosis through mechanisms comparable to alcoholic liver disease, hence the term "fructoholic liver disease." Conclusion: The importance of implementing reliable global strategies, such as education campaigns to promote healthy diet, increasing taxes on foods that contain added sugars, subsidies to promote accessibility to fruit and vegetables, and strict food industry regulation to reduce sugar intake in children and adolescents, cannot be overemphasized.

Type de document Article de périodique (Journal article) – Article de recherche
Type d'accès Accès libre
Année de publication 2019
Langue Anglais
Information sur le périodique "Hepatology Communications" - Vol. 3, no.1, p. 44-51 (2019)
Editeur Wiley
issn 2471-254X
Statut de la publication Publié
Affiliations UCL - SSS/IREC/PEDI - Pôle de Pédiatrie
UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique
Liens
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Référence bibliographique Ribeiro, Andreia ; Igual-Perez, Maria-Jose ; Santos Silva, Ermelinda ; Sokal, Etienne. Childhood Fructoholism and Fructoholic Liver Disease : Hepatology Communications. In: Hepatology Communications, Vol. 3, no.1, p. 44-51 (2019)
Permalien http://hdl.handle.net/2078.1/212387