All Publications

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1. • Journal article

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   Effect of anti-interleukin drugs in patients with COVID-19 and signs of cytokine release syndrome (COV-AID): a factorial, randomised, controlled trial.

   Declercq, Jozefien Van Damme, Karel F A De Leeuw, Elisabeth Maes, Bastiaan Bosteels, Cedric Tavernier, Simon J De Buyser, Stefanie Colman, Roos Hites, Maya Verschelden, Gil Fivez, Tom Moerman, Filip Demedts, Ingel K Dauby, Nicolas De Schryver, Nicolas Govaerts, Elke Vandecasteele, Stefaan J Van Laethem, Johan Anguille, Sebastien van der Hilst, Jeroen Misset, Benoit Slabbynck, Hans Wittebole, Xavier[UCL] Liénart, Fabienne Legrand, Catherine[UCL] Buyse, Marc Stevens, Dieter Bauters, Fre Seys, Leen J M Aegerter, Helena Smole, Ursula Bosteels, Victor Hoste, Levi Naesens, Leslie Haerynck, Filomeen Vandekerckhove, Linos Depuydt, Pieter van Braeckel, Eva Rottey, Sylvie Peene, Isabelle Van Der Straeten, Catherine Hulstaert, Frank Lambrecht, Bart N (2021) The Lancet. Respiratory medicine — Vol. 9, no.12, p. 1427-1438 (2021)
2. • Journal article

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   Oncological care organisation during COVID-19 outbreak

   Onesti, Concetta Elisa Rugo, Hope S. Generali, Daniele Peeters, Marc Zaman, Khalil Wildiers, Hans Harbeck, Nadia Martin, Miguel Cristofanilli, Massimo Cortes, Javier Tjan-Heijnen, Vivianne Hurvitz, Sara A. Berchem, Guy Tagliamento, Marco Campone, Mario Bartsch, Rupert De Placido, Sabino Puglisi, Fabio Rottey, Sylvie Müller, Volkmar Ruhstaller, Thomas Machiels, Jean-Pascal[UCL] Conte, PierFranco Awada, Ahmad Jerusalem, Guy (2020) ESMO Open — Vol. 5, no. 4, p. e000853 [1-8] (2020)
3. • Journal article

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   Impact of solid cancer on in-hospital mortality overall and among different subgroups of patients with COVID-19: a nationwide, population-based analysis.

   de Azambuja, Evandro Brandão, Mariana Wildiers, Hans Laenen, Annouschka Aspeslagh, Sandrine Fontaine, Christel Collignon, Joelle Lybaert, Willem Verheezen, Jolanda Rutten, Annemie Vuylsteke, Peter[UCL] Goeminne, Jean-Charles[UCL] Demey, Wim Van Beckhoven, Dominique Deblonde, Jessika Rottey, Sylvie Geukens, Tatjana Punie, Kevin Belgian Collaborative Group on COVID-19 Hospital Surveillance and the Belgian Society of Medical Oncology (BSMO) Belkhir, Leïla[UCL] (2020) ESMO open — Vol. 5, no. 5, p. e000947 [1-11] (2020)
4. • Journal article

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   Phase 1 Study Evaluating the Association of the Cyclin-Dependent Kinase 4/6 Inhibitor Ribociclib and Cetuximab in Recurrent/Metastatic p16-Negative Squamous Cell Carcinoma of the Head and Neck.

   Seront, Emmanuel Schmitz, Sandra[UCL] Papier, Matthias[UCL] van Maanen, Aline[UCL] Henry, Stéphanie Lonchay, Christophe Rottey, Sylvie van Caloen, Gabrielle Machiels, Jean-Pascal[UCL] (2019) Frontiers in oncology — Vol. 9, p. 155 [1-6] (2019)
5. • Journal article

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   Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME).

   De Bruijn, Roderick Emile Mulders, Peter Jewett, Michael A Wagstaff, John Van Thienen, Johan V Blank, Christian U Van Velthoven, Roland Wood, Lori van Melick, Harm E Aarts, Maureen J Lattouf, Jean B Powles, Thomas De Jong, Igle J Rottey, Sylvie Tombal, Bertrand[UCL] Marreaud, Sandrine Collette, Sandra Collette, Laurence Haanen, John B Bex, Axel (2019) European Urology — Vol. 76, no. 4, p. 437-440 (2019)
6. • Journal article

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   A phase I study of volasertib combined with afatinib, in advanced solid tumors

   Machiels, Jean-Pascal[UCL] Peeters, Marc Herremans , Catherine[UCL] Surmont, Veerle Specenier, Pol De Smet, Marina Pilz, Korinna Strelkowa, Natalja Liu, Dan Rottey, Sylvie (2015) Cancer Chemotherapy and Pharmacology — Vol. 76, no.4, p. 843-851 (2015)
7. • Journal article

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   Which Factors Predict Overall Survival in Patients With Metastatic Castration-Resistant Prostate Cancer Treated With Abiraterone Acetate Post-Docetaxel?

   Van Praet, Charles Rottey, Sylvie Van Hende, Fransien Pelgrims, Gino Demey, Wim Van Aelst, Filip Wynendaele, Wim Gil, Thierry Schatteman, Peter Filleul, Bertrand Schallier, Denis Machiels, Jean-Pascal[UCL] Schrijvers, Dirk Everaert, Els D'Hondt, Lionel Werbrouck, Patrick Vermeij, Joanna Mebis, Jeroen Clausse, Marylene Rasschaert, Marika Van Erps, Joanna Verheezen, Jolanda Van Haverbeke, Jan Goeminne, Jean-Charles Lumen, Nicolaas (2017) Clinical Genitourinary Cancer — Vol. 15, no. 4, p. 502-508 (2017)
8. • Speech

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   Abstract CT152: First in human study with EOS100850, a novel potent A2A antagonist, shows excellent tolerance and clinical benefit in immune resistant advanced cancers

   Buisseret, Laurence Rottey, Sylvie de Bono, Johann Mossakowski, Manon[UCL] Delafontaine, Brant Manickavasagar, Thubeena Kotecki, Nuria Martinoli, Chiara Schneider, Manfred De Henau, Olivier Chevron, Patricia Lager, Joanne Machiels, Jean-Pascal[UCL] (2020) Proceedings: AACR Annual Meeting 2020; April 27-28, 2020 and June 22-24, 2020; Philadelphia, PA — Philadelphia
9. • Journal article

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   Erdafitinib in patients with advanced solid tumours with FGFR alterations (RAGNAR): an international, single-arm, phase 2 study

   Pant, Shubham Schuler, Martin Iyer, Gopa Witt, Olaf Doi, Toshihiko Qin, Shukui Tabernero, Josep Reardon, David A Massard, Christophe Minchom, Anna Lugowska, Iwona Carranza, Omar Arnold, Dirk Gutierrez, Martin Winter, Helen Stuyckens, Kim Crow, Lauren Najmi, Saltanat Hammond, Constance Thomas, Shibu Santiago-Walker, Ademi Triantos, Spyros Sweiti, Hussein Loriot, Yohann Carranza, Omar Greco, Martin Alberto Coward, Jim Joshua, Anthony Karapetis, Christos Hart, Christopher Zhang, Alison Prenen, Hans Goeminne, Jean-Charles Machiels, Jean-Pascal[UCL] Rottey, Sylvie Corassa, Marcelo Molin, Graziela Zibetti Dal Tiscoski, Katsuki Jardim, Denis Leonardo Fontes Mak, Milena Fu, Wei Yao, Herui Huang, Jing Jiang, Haiping Qin, Shukui Chen, Baoshi Yan, Dong Yang, Yu Loriot, Yohann Le Tourneau, Christophe Penel, Nicolas Salas, Sébastien Blay, Jean-Yves Brachet, Pierre-Emmanuel Durando, Xavier Emambux, Sheik Ravaud, Alain Folprecht, Gunnar Arnold, Dirk Schuler, Martin Ahrens, Marit Golf, Alexander Haag, Georg Martin Lordick, Florian Desuki, Alexander Cazzaniga, Marina Ciardiello, Fortunato Milella, Michele Koyama, Takafumi Hirooka, Yoshiki Okamoto, Wataru Aogi, Kenjiro Kuboki, Yasutoshi Lee, Jungyun Kim, Sung-Bae Ahn, Myung-Ju Chang, Jong Hee Kim, Yong-Man Nam, Do-Hyun Park, Jae-Sung Lugowska, Iwona Paz-Ares, Luis Moreno, Victor Cervantes, Andres Calvo, Mariona Falcon, Alejandro Gonzalez, Antonio Tabernero, Josep Martinez Bueno, Alejandro García-Corbacho, Javier Longo, Federico Yen, Chia-Jui Chen, Jen-Shi Hou, Ming-Feng Chao, Yee Rau, Kun-Ming Chiu, Tai-Jan Feng, Yin-Hsun Hsu, Chih-Hung Huang, Wen-Tsung Lai, Kuan-Ming Yeh, Su-peng Palmer, Daniel Minchom, Anna Winter, Helen Welsh, Liam Plummer, Ruth Iyer, Gopakumar Gutierrez, Martin Bilen, Mehmet Arrowsmith, Edward Pant, Shubham Spigel, David Robert Zandberg, Dan Paul Doroshow, Deborah Lu-Emerson, Christine Moezi, Mehdi Paulson, Scott Reardon, David Ward, Patrick Chaves, Jorge Grigg, Claud Hussein, Atif Manda, Sudhir Monticelli, Michael Qamar, Rubina Richey, Stephen L Tamura, David Wilks, Sharon (2023) The Lancet Oncology — Vol. 24, no.8, p. 925-935 (2023)
10. • Journal article

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    Prospective non-interventional multicenter observational trial of first-line anti-cancer treatment in patients with metastatic renal cell cancer in Belgium

    Cornelis, Natasha Vermassen, Tijl Schallier, Denis Machiels, Jean-Pascal[UCL] Gil, Thierry Debruyne, Philip R D'hondt, Randal Bols, Alain Schrijvers, Dirk Mebis, Jeroen Lumen, Nicolaas Rottey, Sylvie (2014) Acta Clinica Belgica — , p. 2295333714Y.000 (2014)
11. • Journal article

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    Chimeric Antigen Receptor-T Cells for Targeting Solid Tumors: Current Challenges and Existing Strategies.

    Springuel, Lorraine Lonez, Caroline Alexandre, Bertrand Van Cutsem, Eric Machiels, Jean-Pascal[UCL] Van Den Eynde, Marc[UCL] Prenen, Hans Hendlisz, Alain Shaza, Leila Carrasco, Javier Canon, Jean-Luc Opyrchal, Mateusz Odunsi, Kunle Rottey, Sylvie Gilham, David E Flament, Anne Lehmann, Frédéric F (2019) BioDrugs — Vol. 33, no. 5, p. 515-537 (2019)
12. • Journal article

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    A randomized, double-blind, placebo-controlled study to assess QTc interval prolongation of standard dose aflibercept in cancer patients treated with docetaxel

    Maison-Blanche, Pierre Vermorken, Jan B Goksel, Tuncay Machiels, Jean-Pascal[UCL] Agarwala, Sanjiv Rottey, Sylvie Daugaard, Gedske Volovat, Constantin Scheulen, Max Sengeløv, Lisa Grecea, Dana Eniu, Alexandru Jäger, Elke Meiri, Eyal Cascinu, Stefano Strumberg, Dirk Demir, Gokhan Clemens, Michael Pinotti, Graziella Nardi, Mario Guthrie, Troy Boelle, Emmanuelle Magherini, Emmanuelle (2013) Journal of Cardiovascular Pharmacology — Vol. 61, no.6, p. 495-504 (2013)
13. • Journal article

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    On-Target Pharmacodynamic Activity of the PI3K Inhibitor Copanlisib in Paired Biopsies from Patients with Malignant Lymphoma and Advanced Solid Tumors.

    Morschhauser, Franck Machiels, Jean-Pascal[UCL] Salles, Gilles Rottey, Sylvie Rule, Simon Aj Cunningham, David Peyrade, Frederic Fruchart, Christophe Arkenau, Hendrik-Tobias Genvresse, Isabelle Liu, Li Köchert, Karl Shen, Kui Kneip, Christoph Peña, Carol E Grevel, Joachim Zhang, Jun Cisternas, Galia Reschke, Susanne Granvil, Camille Awada, Ahmad (2020) Molecular cancer therapeutics — Vol. 19, no. 2, p. 468-478 (2020)
14. • Journal article

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    Efficacy and safety of pazopanib in patients with metastatic renal cell carcinoma

    Hutson, Thomas E. Davis, Ian D. Machiels, Jean-Pascal[UCL] De Souza, Paul L. Rottey, Sylvie Hong, Bao-Fa Epstein, Richard J Baker, Katherine L McCann, Lauren Crofts, Theresa Pandite, Lini Figlin, Robert A (2010) Journal of Clinical Oncology — Vol. 28, no. 3, p. 475-480 (2010)
15. • Journal article

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    Phase I/IIa Trial of BMS-986148, an Anti-mesothelin Antibody-drug Conjugate, Alone or in Combination with Nivolumab in Patients with Advanced Solid Tumors.

    Rottey, Sylvie Clarke, Jeffrey Aung, Kyaw Machiels, Jean-Pascal[UCL] Markman, Ben Heinhuis, Kimberley M Millward, Michael Lolkema, Martijn Patel, Sandip Pravin de Souza, Paul Duca, Matteo Curigliano, Giuseppe Santoro, Armando Koyama, Takafumi Brown, Michelle Vezina, Heather He, Chunsheng Chu, Quincy Siu-Chung (2022) Clinical cancer research — Vol. 28, no. 1, p. 95-105 (2022)
16. • Journal article

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    Phase II study of dual phosphoinositol-3-kinase (PI3K) and mammalian target of rapamycin (mTOR) inhibitor BEZ235 in patients with locally advanced or metastatic transitional cell carcinoma (TCC)

    Seront, Emmanuel[UCL] Rottey, Sylvie Filleul, Bertrand Glorieux, Philippe Goeminne, Jean-Charles Verschaeve, Vincent Vandenbulcke, Jean-Marie Sautois, Brieuc Boegner, Petra Gillain, Aline van Maanen, Aline[UCL] Machiels, Jean-Pascal[UCL] (2016) BJU International — Vol. 118, no. 3, p. 408-415 (2016)
17. • Journal article

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    Biomarker Analysis in a Phase II Study of Sunitinib in Patients with Advanced Melanoma

    Decoster, Lore Vande Broek, Isabelle Neyns, Bart Majois, Françoise Baurain, Jean-François[UCL] Rottey, Sylvie Rorive, Andrée Anckaert, Ellen De Mey, Johan De Brakeleer, Sylvia De Grève, Jacques (2015) Anticancer Research : international journal of cancer research and treatment — Vol. 35, no.12, p. 6893-6899 (2015)
18. • Journal article

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    Abiraterone acetate post-docetaxel for metastatic castration-resistant prostate cancer in the Belgian compassionate use program

    Van Praet, Charles Rottey, Sylvie Van Hende, Fransien Pelgrims, Gino Demey, Wim Van Aelst, Filip Wynendaele, Wim Gil, Thierry Schatteman, Peter Filleul, Bertrand Schallier, Dennis Machiels, Jean-Pascal[UCL] Schrijvers, Dirk Everaert, Els D'Hondt, Lionel[UCL] Werbrouck, Patrick Vermeij, Joanna Mebis, Jeroen Clausse, Marylene Rasschaert, Marika Van Erps, Joanna Verheezen, Jolanda Van Haverbeke, Jan Goeminne, Jean-Charles Lumen, Nicolaas (2016) Urologic Oncology : seminars and original investigations — Vol. 34, no. 6, p. 254.e7-254.e13 (2016)
19. • Journal article

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    Belgian expert consensus for tumor-agnostic treatment of NTRK gene fusion-driven solid tumors with larotrectinib

    Awada, Ahmad Berghmans, Thierry Clement, Paul M. Cuppens, Kristof De Wilde, Bram Machiels, Jean-Pascal[UCL] Pauwels, Patrick Peeters, Marc Rottey, Sylvie Van Cutsem, Eric (2022) Critical reviews in oncology/hematology — Vol. 169, p. 103564 [11-8] (2022)
20. • Journal article

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    Celyad's novel CAR T-cell therapy for solid malignancies.

    Lonez, Caroline Hendlisz, Alain Shaza, Leila Aftimos, Philippe Vouche, Michaël Donckier, Vincent Machiels, Jean-Pascal[UCL] Van den Eynde, Marc[UCL] Canon, Jean-Luc Carrasco, Javier Odunsi, Kunle Sahebjam, Solmaz Rottey, Sylvie Braun, Nathalie Verma, Bikash Gilham, David E Lehmann, Frédéric F (2018) Current research in translational medicine — Vol. 66, no.2, p. 53-56 (2018)
21. • Journal article

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    Comparison of Immediate vs Deferred Cytoreductive Nephrectomy in Patients with Synchronous Metastatic Renal Cell Carcinoma Receiving Sunitinib: The SURTIME Randomized Clinical Trial.

    Bex, Axel Mulders, Peter Jewett, Michael Wagstaff, John van Thienen, Johannes V Blank, Christian U van Velthoven, Roland Del Pilar Laguna, Maria Wood, Lori van Melick, Harm H E Aarts, Maureen J Lattouf, J B Powles, Thomas de Jong, Igle Jan Rottey, Sylvie Tombal, Bertrand[UCL] Marreaud, Sandrine Collette, Sandra Collette, Laurence Haanen, John (2019) JAMA oncology — Vol. 5, no. 2, p. 164-170 (2019)
22. • Journal article

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    A phase II study of monalizumab in patients with recurrent/metastatic squamous cell carcinoma of the head and neck: The I1 cohort of the EORTC-HNCG-1559 UPSTREAM trial.

    Galot, Rachel[UCL] Le Tourneau, Christophe Saada-Bouzid, Esma Daste, Amaury Even, Caroline Debruyne, Philip Henry, Stéphanie[UCL] Zanetta, Sylvie Rutten, Anemie Licitra, Lisa Canon, Jean-Luc Kaminsky, Marie-Christine Specenier, Pol Rottey, Sylvie Guigay, Joël Kong, Anthony Tinhofer, Inge Borcoman, Edith Dirix, Lieve Raveloarivahy, Tiana Fortpied, Catherine Vanlancker, Maureen Morfouace, Marie Govaerts, Anne-Sophie Machiels, Jean-Pascal[UCL] (2021) European journal of cancer — Vol. 158, p. 17-26 (2021)
23. • Journal article

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    An open-label study to investigate the cardiac safety profile of cabazitaxel in patients with advanced solid tumors

    Maison-Blanche, Pierre Dakhil, Shaker Baron, Ari Rottey, Sylvie Millard, Fred Daugaard, Gedske Machiels, Jean-Pascal[UCL] Conkright, William Sharma, Sunil Soetekouw, Patricia M M B Yachnin, Jeffrey Sengeløv, Lisa Van Veldhuizen, Peter Agarwala, Sanjiv S Sémiond, Dorothée Chadjaa, Mustapha Shen, Liji Wade, James L (2014) Cancer Chemotherapy and Pharmacology — Vol. 73, no.6, p. 1241-1252 (2014)
24. • Journal article

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    Determination of an adequate screening tool for identification of vulnerable elderly head and neck cancer patients treated with radio(chemo)therapy

    Pottel, Lies Boterberg, Tom Pottel, Hans Goethals, Laurence Van Den Noortgate, Nele Duprez, Fréderic De Neve, Wilfried Rottey, Sylvie Geldhof, Kurt Van Eygen, Koen Kargar-Samani, Khalil Ghekiere, Véronique Cornelis, Frank[UCL] Mohile, Supriya Debruyne, Philip R. (2012) Journal of Geriatric Oncology — Vol. 3, no.1, p. 24-32 (2012)
25. • Journal article

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    Agreement of Gleason score on prostate biopsy and radical prostatectomy specimen: is there improvement with increased number of biopsy cylinders and the 2005 revised Gleason scoring?

    Van Praet, Charles Libbrecht, Louis D'Hondt, Frederiek Decaestecker, Karel Fonteyne, Valérie Verschuere, Stephanie Rottey, Sylvie Praet, Marleen De Visschere, Pieter Lumen, Nicolaas (2014) Clinical Genitourinary Cancer — Vol. 12, no.3, p. 160-166 (2014)

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