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Pattern recognition with the optic nerve visual prosthesis.

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Veraart, Claude [UCL] Wanet-Defalque, Marie-Chantal [UCL] Gérard, Benoît [UCL] Vanlierde, Annick [UCL] Delbeke, Jean [UCL]

A volunteer with retinitis pigmentosa and no residual vision was chronically implanted with an optic nerve electrode connected to an implanted neurostimulator and antenna. An external controller with telemetry was used for electrical activation of the nerve which resulted in phosphene perception. Open-loop stimulation allowed the collection of phosphene attributes and the ability to elicit perception of simple geometrical patterns. Low perception thresholds allowed for large current intensity range within safety limits. In a closed-loop paradigm, the volunteer was using a head-worn video camera to explore a projection screen. The volunteer underwent performance evaluation during the course of a training program with 45 simple patterns. After learning, the volunteer reached a recognition score of 63% with a processing time of 60 s. Mean performance in orientation discrimination reached 100% with a processing time of 8 s.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2003
Journal information "Artificial organs" - Vol. 27, no. 11, p. 996-1004 (2003)
Peer reviewed yes
issn 0160-564X
Publication status Publié
Affiliation UCL - MD/FSIO - Département de physiologie et pharmacologie
MESH Subject Electric Stimulation - methods ; Electrodes, Implanted ; Female ; Humans ; Middle Aged ; Optic Nerve - physiology ; Pattern Recognition, Visual ; Phosphenes - physiology ; Prostheses and Implants ; Retinitis Pigmentosa - rehabilitation ; Task Performance and Analysis
Keywords Optic nerve ; Human ; Retinitis pigmentosa ; Spiral cuff electrode ; Visual prosthetis ; Vision rehabilitation
Links
  1. Buisseret P, Imbert M, Visual cortical cells: their developmental properties in normal and dark reared kittens., 10.1113/jphysiol.1976.sp011293
  2. Veraart C., De Volder A.G., Wanet-Defalque M.C., Bol A., Michel Ch., Goffinet A.M., Glucose utilization in human visual cortex is abnormally elevated in blindness of early onset but decreased in blindness of late onset, 10.1016/0006-8993(90)90735-t
  3. Veraart C, J Med Eng Technol, 13, 57 (1989)
  4. Bach-y-Rita P, Nature, 221, 963 (1969)
  5. Capelle C., Trullemans C., Arno P., Veraart C., A real-time experimental prototype for enhancement of vision rehabilitation using auditory substitution, 10.1109/10.720206
  6. Veraart C., Wanet-Defalque M. -C., Representation of locomotor space by the blind, 10.3758/bf03210501
  7. Arno P, Perception, 28, 1013 (1999)
  8. Arno Patricia, De Volder Anne G., Vanlierde Annick, Wanet-Defalque Marie-Chantal, Streel Emmanuel, Robert Annie, Sanabria-Bohórquez Sandra, Veraart Claude, Occipital Activation by Pattern Recognition in the Early Blind Using Auditory Substitution for Vision, 10.1006/nimg.2000.0731
  9. Brindley G. S., Lewin W. S., The sensations produced by electrical stimulation of the visual cortex, 10.1113/jphysiol.1968.sp008519
  10. Schmidt EM, Brain, 119, 507 (1996)
  11. Stone John L., Morphometric Analysis of Macular Photoreceptors and Ganglion Cells in Retinas With Retinitis Pigmentosa, 10.1001/archopht.1992.01080230134038
  12. Santos Arturo, Preservation of the Inner Retina in Retinitis Pigmentosa : A Morphometric Analysis, 10.1001/archopht.1997.01100150513011
  13. Humayun Mark S., de Juan Jr. Eugene, Weiland James D., Dagnelie Gislin, Katona Steve, Greenberg Robert, Suzuki Satoshi, Pattern electrical stimulation of the human retina, 10.1016/s0042-6989(99)00052-8
  14. Grumet Andrew E, Wyatt John L, Rizzo Joseph F, Multi-electrode stimulation and recording in the isolated retina, 10.1016/s0165-0270(00)00246-6
  15. Zrenner E, Ophthalmic Res, 29, 269 (1997)
  16. Zrenner E., Will Retinal Implants Restore Vision?, 10.1126/science.1067996
  17. Rizzo JF, Invest Ophth Vis Sci, 42, S5045 (2001)
  18. Veraart C., Grill W.M., Mortimer J.T., Selective control of muscle activation with a multipolar nerve cuff electrode, 10.1109/10.237694
  19. Veraart Claude, Raftopoulos Christian, Mortimer J.Thomas, Delbeke Jean, Pins Delphine, Michaux Géraldine, Vanlierde Annick, Parrini Simone, Wanet-Defalque Marie-Chantal, Visual sensations produced by optic nerve stimulation using an implanted self-sizing spiral cuff electrode, 10.1016/s0006-8993(98)00977-9
  20. Delbeke J, Invest Ophth Vis Sci, 42, 291 (2001)
  21. Delbeke Jean, Wanet-Defalque M.C., Gerard B., Troosters M., Michaux G., Veraart C., The Microsystems Based Visual Prosthesis for Optic Nerve Stimulation, 10.1046/j.1525-1594.2002.06939.x
  22. Delbeke Jean, Oozeer Medhy, Veraart Claude, Position, size and luminosity of phosphenes generated by direct optic nerve stimulation, 10.1016/s0042-6989(03)00013-0
  23. Parrini S, Med Biol Eng Comput, 38, 454 (2000)
Bibliographic reference Veraart, Claude ; Wanet-Defalque, Marie-Chantal ; Gérard, Benoît ; Vanlierde, Annick ; Delbeke, Jean. Pattern recognition with the optic nerve visual prosthesis.. In: Artificial organs, Vol. 27, no. 11, p. 996-1004 (2003)
Permanent URL http://hdl.handle.net/2078.1/9665