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The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS.

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Dandoy, Damien [UCL] Fremaux, Christophe [DANISCO France] de Frahan, Marie Henry [UCL] Horvath, Philippe [DANISCO France] Boyaval, Patrick [Danisco France] Hols, Pascal [UCL] Fontaine, Laetitia [UCL]

In industrial fermentation processes, the rate of milk acidification by Streptococcus thermophilus is of major technological importance. The cell-envelope proteinase PrtS was previously shown to be a key determinant of the milk acidification activity in this species. The PrtS enzyme is tightly anchored to the cell wall via a mechanism involving the typical sortase A (SrtA) and initiates the breakdown of milk casein into small oligopeptides. The presence or absence of PrtS divides the S. thermophilus strains into two phenotypic groups i.e. the slow and the fast acidifying strains. The aim of this study was to improve the milk acidification rate of slow S. thermophilus strains, and hence optimise the fermentation process of dairy products.

Document type Article de périodique (Journal article) – Article de recherche – Journal Article, Research Support, Non-U.S. Gov't
Access type Accès libre
Publication date 2011
Language Anglais
Journal information "Microbial Cell Factories" - Vol. 10 Suppl 1, p. S21 (2011)
Peer reviewed yes
Publisher BioMed Central Ltd. ((United Kingdom) London)
issn 1475-2859
e-issn 1475-2859
Publication status Publié
Affiliations UCL - SST/ISV - Institut des sciences de la vie
DANISCO France - Recherche et Développement Fermentation lactique
Danisco France - Recherche et Développement Fermentation lactique
UCL - SST/LIBST - Louvain Institute of Biomolecular Science and Technology
Keywords Competence ; casein degradation ; 3111
Links
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Bibliographic reference Dandoy, Damien ; Fremaux, Christophe ; de Frahan, Marie Henry ; Horvath, Philippe ; Boyaval, Patrick ; et. al. The fast milk acidifying phenotype of Streptococcus thermophilus can be acquired by natural transformation of the genomic island encoding the cell-envelope proteinase PrtS.. In: Microbial Cell Factories, Vol. 10 Suppl 1, p. S21 (2011)
Permanent URL http://hdl.handle.net/2078.1/95662