Arany, E
[]
Strutt, B
[]
Romanus, P
[UCL]
Remacle, C
[UCL]
Reusens, Brigitte
[UCL]
Hill, D J
[]
We hypothesised that nutritional taurine, which is important for the development of the endocrine pancreas and reduces cytokine-induced apoptosis in pancreatic beta cells, would prevent or delay the onset of autoimmune diabetes, if given early in life to the non-obese diabetic (NOD) mouse.
- Kikutani H, Makino S (1992) The murine autoimmune diabetes model: NOD and related strains. Adv Immunol 51:285?322
- Lampeter EF, Signore A, Gale EAM, Pozzili P (1989) Lessons from the NOD mouse for the pathogenesis and immunotherapy of human type 1 (insulin-dependent) diabetes mellitus. Diabetologia 32:703?708
- Castano L, Eisenbarth, GS (2001) Type I diabetes: a chronic autoimmune disease of human, mouse and rat. Annu Rev Immunol 8:647?679
- Signore A, Pozzili P, Gale EAM, Andreani D, Beverley PCL (1989) The natural history of lymphocyte subsets infiltrating the pancreas of the NOD mice. Diabetologia 32:282?289
- Trudeau JD, Dutz JP, Arany E, Hill DJ, Fieldus WE, Finegood DT (2000) Neonatal ?-cell apoptosis: A trigger for autoimmune diabetes? Diabetes 49:1?7
- Huxtable RJ (1992) Physiological actions of taurine. Physiol Rev 72:101?163
- Huxtable R, Fanconi F, Gironi A (1987) The biology of taurine. Methods and mechanisms. Plenum Press, New York
- Briel G, Gylfe E, Hellman B, Neuhoff V (1972) Microdetermination of free amino acids in pancreatic islets isolated from obese-hyperglycemic mice. Acta Physiol Scand 84:247?253
- Bustamente J, Lobo MVT, Alonso NTA et al. (2001) An osmotic sensitive taurine pool is located in rat pancreatic islet cells containing glucagon and somatostatin. Am J Endocr Metab 281:E1275?E1285
- Lake Norma, Wright Erin D., Lapp Wayne S., Effects of Taurine Deficiency on Immune Function in Mice, Advances in Experimental Medicine and Biology (1992) ISBN:9781461365204 p.241-243, 10.1007/978-1-4615-3436-5_28
- Schuller-Levis G, Mehta PD, Rudelli R, Sturman J (1990) Immunological consequences of taurine deficiency in cats. J Leucocyte Biol 47:321?331
- Palmi M, Youmbi GT, Fusi F et al. (1999) Potentiation of mitochondrial Ca2+ sequestration by taurine. Biochem Pharmacol 58:1123?1131
- Wu QD, Wang JH, Fennessy F, Redmond HP, Bouchier-Hayes D (1999) Taurine prevents high-glucose-induced human vascular endothelial cell apoptosis. Am J Physiol 277:C1229?C1238
- Barua M, Liu Y, Quinn MR (2001) Taurine chloramine inhibits inducible nitric oxide synthase and TNF-alpha gene expression in activated alveolar macrophages: decreased NF-kappa B activation and Ikappa B kinase activity. J Immunol 167:2275?2281
- Takikawa Y, Miyoshi H, Rust C et al (2001) The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes. Gastroenterology 120:1810?1817
- Reusens B, Dahri S, Snoeck A et al. (1995) Long term consequences of diabetes and its complications may have a fetal origin: experimental and epidemiological evidences. In: Cowett RM (ed.) Nestlé Nutrition Workshop Series, vol 25. Raven Press, New York, pp 187?198
- Petrik J, Reusens B, Arany E, Remacle C, Hoet JJ, Hill DJ (1999) A low protein diet alters the balance of islet cell replication and apoptosis in the fetal and neonatal rat, and is associated with a reduced pancreatic expression of insulin-like growth factor-II. Endocrinology 140:4861?4873
- Boujendar S, Reusens B, Merezak S et al. (2002) Taurine supplementation to a low protein diet during foetal and early postnatal life restores normal proliferation and apoptosis of rat pancreatic islets. Diabetologia 45:856?866
- Boujendar S, Arany E, Hill DJ, Remacle C, Reusens B (2003) Taurine supplementation during fetal life reverses the vascular impairment caused to the endocrine pancreas by a low protein diet. J Nutr 133:2820?2825
- Merezak S, Hardikar AA, Yajnik CS, Remacle C, Reusens B (2001) Intrauterine low protein diet increases fetal ß cell sensitivity to NO and IL-1?: the protective role of taurine. J Endocrinol 171:299?308
- Cherif H, Reusens B, Ahn MT, Hoet JJ, Reusens B (1998) Effects of taurine on the insulin secretion of rat fetal islets from dams fed a low protein diet. J Endocrinol 159:341?348
- Merezak S, Reusens B, Renard A et al. (2004) Early low protein diet increases the vulnerability of rat adult rat islet to cytokines: preventive role of taurine. Diabetologia 47:669?675
- Hsu S M, Raine L, Fanger H, Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures., 10.1177/29.4.6166661
- Bock T, Pakkenberg B, Buschard K (2003) Increased islet volume but unchanged islet number in ob/ob mice. Diabetes 52:1716?1722
- Bock T, Kynel A, Pakkenberg B, Buschard K (2003) The postnatal growth of the beta-cell mass in pigs. J Endocrinol 179:245?252
- Hoorfar J, Buschard K, Dagnaes-Hansen F (1993) Prophylactic nutritional modification of the incidence of diabetes in autoimmune non-obese diabetic (NOD) mice. Br J Nutr 69:597?607
- Pozzilli P, Signore A, Williams AJK, Beales PE (1993) NOD mouse colonies around the world?recent facts and figures. Immunol Today 14:193?196
- Marcinkiewicz J, Nowak B, Grabowska A, Bobek M, Petrovska L, Chain B (1999) Regulation of murine dendritic cell functions in vitro by taurine chloramine, a major product of the neutrophil myelopeoxidase-halide system. Immunology 98:371?378
- Barua M., Liu Y., Quinn M. R., Taurine Chloramine Inhibits Inducible Nitric Oxide Synthase and TNF- Gene Expression in Activated Alveolar Macrophages: Decreased NF- B Activation and I B Kinase Activity, 10.4049/jimmunol.167.4.2275
Bibliographic reference |
Arany, E ; Strutt, B ; Romanus, P ; Remacle, C ; Reusens, Brigitte ; et. al. Taurine supplement in early life altered islet morphology, decreased insulitis and delayed the onset of diabetes in non-obese diabetic mice.. In: Diabetologia, Vol. 47, no. 10, p. 1831-7 (2004) |
Permanent URL |
http://hdl.handle.net/2078.1/92788 |