Hue, Louis
[UCL]
Certain amino acids such as glutamine and proline stimulate liver glycogen synthesis and lipogenesis. This implies cell swelling and leads to the activation of glycogen synthase and acetyl-CoA carboxylase by a common mechanism. This mechanism results from the cell response to swelling and involves a fall in intracellular concentration of chloride ions and an increase in intracellular concentration of glutamate and aspartate. These ions indeed regulate the protein phosphatases that activate glycogen synthase and acetyl-CoA carboxylase.
Bibliographic reference |
Hue, Louis. [Control of liver carbohydrate and lipid metabolism by cell volume.].12th Congress of the Societe-Francaise-d-Endocrinologie (TOULOUSE(France), Sep 08-10, 1994). In: Annales d'Endocrinologie, Vol. 56, no. 6, p. 599-601 (1995) |
Permanent URL |
http://hdl.handle.net/2078.1/62948 |