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Paucity of presumptive Ruffini corpuscles in the index finger pad of humans

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Pare, M Cornu, Olivier [UCL] Behets Wydemans, Catherine [UCL]

Classically recognized as the cutaneous stretch receptors associated with the slowly adapting type II (SAII) primary afferents, Ruffini corpuscles have rarely been reported in the skin, despite numerous histologic investigations. Electrophysiological recordings of the primary afferents in humans suggest that SAII fibers represent approximately 15% of the myelinated mechanosensitive axons in the peripheral nerves innervating the volar surface of the hand. In the present study, an analysis of glabrous skin was conducted in human donors to assess the distribution of Ruffini and Ruffini-like corpuscles in the distal phalanx of the index finger. Only one presumptive Ruffini corpuscle was found in the skin processed for double immunofluorescence labeling with antibodies against protein gene product 9.5 and neurofilament 200-kDa subunit. Based on their relatively scattered distributions, we conclude that very few SAII primary afferents are likely to terminate as Ruffini corpuscles in human glabrous skin. (C) 2003 Wiley-Liss, Inc.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2003
Language Anglais
Journal information "The Journal of Comparative Neurology" - Vol. 456, no. 3, p. 260-266 (2003)
Peer reviewed yes
Publisher Wiley-liss (New York)
issn 0021-9967
e-issn 1096-9861
Publication status Publié
Affiliations UCL - Cliniques universitaires Saint-Luc
UCL - SSS/IREC/CARS - Computer Assisted Robotic Surgery
UCL - (SLuc) Service d'orthopédie et de traumatologie de l'appareil locomoteur
Keywords digit ; sensory endings ; mechanoreceptors ; human
Links
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Bibliographic reference Pare, M ; Cornu, Olivier ; Behets Wydemans, Catherine. Paucity of presumptive Ruffini corpuscles in the index finger pad of humans. In: The Journal of Comparative Neurology, Vol. 456, no. 3, p. 260-266 (2003)
Permanent URL http://hdl.handle.net/2078.1/41281