User menu

A peptide derived from melanocytic protein gp100 and presented by HLA-B35 is recognized by autologous cytolytic T lymphocytes on melanoma cells

Bibliographic reference Vigneron, Nathalie ; Ooms, Annie ; Morel, Sandra ; Ma, Wenbin ; Degiovanni, Gérard ; et. al. A peptide derived from melanocytic protein gp100 and presented by HLA-B35 is recognized by autologous cytolytic T lymphocytes on melanoma cells. In: Tissue Antigens, Vol. 65, no. 2, p. 156-162 (2005)
Permanent URL
  1. Boon T., Tumor Antigens Recognized by T Lymphocytes, 10.1146/annurev.immunol.12.1.337
  2. Brichard V., The tyrosinase gene codes for an antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas, 10.1084/jem.178.2.489
  3. Wolfel T, Eur J Immunol, 24, 759 (1994)
  4. Cox AL, Science, 264, 716 (1994)
  5. Kawakami Y., Identification of the immunodominant peptides of the MART-1 human melanoma antigen recognized by the majority of HLA-A2-restricted tumor infiltrating lymphocytes, 10.1084/jem.180.1.347
  6. Coulie P. G., A new gene coding for a differentiation antigen recognized by autologous cytolytic T lymphocytes on HLA-A2 melanomas, 10.1084/jem.180.1.35
  7. Rosenberg Steven A., White Donald E., Vitiligo in Patients with Melanoma : Normal Tissue Antigens Can Be Targets for Cancer Immunotherapy, 10.1097/00002371-199601000-00009
  8. Rosenberg Steven A., Yang James C., Schwartzentruber Douglas J., Hwu Patrick, Marincola Francesco M., Topalian Suzanne L., Restifo Nicholas P., Dudley Mark E., Schwarz Susan L., Spiess Paul J., Parkhurst Maria R., Kawakami Yutaka, Seipp Claudia A., Einhorn Jan H., White Donald E., Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma, 10.1038/nm0398-321
  9. Kawakami Y, J Immunol, 154, 3961 (1995)
  10. Nestle Frank O., Alijagic Selma, Gilliet Michel, Sun Yuansheng, Grabbe Stephan, Dummer Reinhard, Burg Günter, Schadendorf Dirk, Vaccination of melanoma patients with peptide- or tumorlysate-pulsed dendritic cells, 10.1038/nm0398-328
  11. J�ger Elke, Maeurer Markus, H�hn Hanni, Karbach Julia, J�ger Dirk, Zidianakis Zacharias, Bakhshandeh-Bath Afsaneh, Orth Jaqueline, Neukirch Claudia, Necker Antje, Reichert Torsten E., Knuth Alexander, Clonal expansion of melan a-specific cytotoxic T lymphocytes in a melanoma patient responding to continued immunization with melanoma-associated peptides, 10.1002/(sici)1097-0215(20000515)86:4<538::aid-ijc16>;2-g
  12. 12. B Van den Eynde, and P van der Bruggen . Peptide database of T-cell defined tumor antigens . Cancer Immun2001 (available from
  13. Kawakami Y, J Immunol, 161, 6985 (1998)
  14. Mori Motomi, Beatty Patrick G., Graves Michael, Boucher Kenneth M., Milford Edgar L., HLA GENE AND HAPLOTYPE FREQUENCIES IN THE NORTH AMERICAN POPULATION : The National Marrow Donor Program Donor Registry1, 10.1097/00007890-199710150-00014
  15. Degiovanni G, Eur J Immunol, 18, 671 (1988)
  16. Murata Makoto, Warren Edus H., Riddell Stanley R., A Human Minor Histocompatibility Antigen Resulting from Differential Expression due to a Gene Deletion, 10.1084/jem.20030044
  17. Uyttenhove Catherine, Pilotte Luc, Théate Ivan, Stroobant Vincent, Colau Didier, Parmentier Nicolas, Boon Thierry, Van den Eynde Benoît J, Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase, 10.1038/nm934
  18. Gaugler B., Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes, 10.1084/jem.179.3.921
  19. Seed B, Proc Natl Acad Sci USA, 84, 3365 (1987)
  20. Zarour Hassane, Smet Charles De, Lehmann Frédéric, Marchand Marie, Lethé Bernard, Romero Pedro, Boon Thierry, Renauld Jean-Christophe, The Majority of Autologous Cytolytic T-Lymphocyte Clones Derived from Peripheral Blood Lymphocytes of a Melanoma Patient Recognize an Antigenic Peptide Derived from Gene Pmel17/gp100, 10.1111/1523-1747.ep12298177
  21. Traversari Catia, van der Bruggen Pierre, Van den Eynde Benoît, Hainaut Philippe, Lemoine Carine, Ohta Nobuyoshi, Old Lloyd, Boon Thierry, Transfection and expression of a gene coding for a human melanoma antigen recognized by autologous cytolytic T lymphocytes, 10.1007/bf00185107
  22. Van den Eynde B., A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma, 10.1084/jem.182.3.689
  23. De Plaen Etienne, Lurquin Christophe, Lethé Bernard, van der Bruggen Pierre, Brichard Vincent, Renauld Jean-Christophe, Coulie Pierre, Van Pel Aline, Boon Thierry, Identification of Genes Coding for Tumor Antigens Recognized by Cytolytic T Lymphocytes, 10.1006/meth.1997.0462
  24. Vigneron N, Cancer Immun, 2, 9 (2002)
  25. Morel Sandra, Ooms Annie, Van Pel Aline, W�lfel Thomas, Brichard Vincent G., Van der Bruggen Pierre, Van den Eynde Beno�t J., Degiovanni G�rard, A tyrosinase peptide presented by HLA-B35 is recognized on a human melanoma by autologous cytotoxic T lymphocytes, 10.1002/(sici)1097-0215(19991210)83:6<755::aid-ijc10>;2-s
  26. Vigneron N., An Antigenic Peptide Produced by Peptide Splicing in the Proteasome, 10.1126/science.1095522
  27. Adema GJ, J Biol Chem, 269, 20126 (1994)
  28. Rammensee Hans-Georg, Bachmann Jutta, Stevanović Stefan, MHC Ligands and Peptide Motifs, ISBN:9783662221648, 10.1007/978-3-662-22162-4
  29. Khanna Rajiv, Silins Sharon L., Weng Zhiping, Gatchell David, Burrows Scott R., Cooper Leanne, Cytotoxic T cell recognition of allelic variants of HLA B35 bound to an Epstein-Barr virus epitope: influence of peptide conformation and TCR-peptide interaction, 10.1002/(sici)1521-4141(199905)29:05<1587::aid-immu1587>;2-n
  30. Gauchat-Feiss D, Transplantation, 60, 869 (1995)