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Duchenne muscular dystrophy: an old anesthesia problem revisited

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Hayes, Jason Veyckemans, Francis [UCL] Bissonnette, Bruno

Patients with Duchenne and Becker muscular dystrophy suffer from a progressive deterioration in muscle secondary to a defect in the dystrophin gene. As such, they are susceptible to perioperative respiratory, cardiac and other complications, such as rhabdomyolysis. Inhalational anesthetic agents have been implicated as a cause of acute rhabdomyolysis that can resemble malignant hyperthermia (MH). This article reviews perioperative 'MH-like' reactions reported in muscular dystrophy patients and groups them into three categories according to clinical presentation. The etiology and underlying pathophysiological process responsible for these reactions is discussed and recommendations are proposed for the safe anesthetic management of these patients.

Document type Article de périodique (Journal article) – Article de recherche – Journal Article, Review
Access type Accès restreint
Publication date 2008
Language Anglais
Journal information "Paediatric Anaesthesia" - Vol. 18, no. 2, p. 100-6 (2008)
Peer reviewed yes
Publisher Blackwell Publishing (Oxford)
issn 1155-5645
e-issn 1460-9592
Publication status Publié
Affiliations UCL - (SLuc) Service d'anesthésiologie
UCL - MD/CHIR - Département de chirurgie
MESH Subject Rhabdomyolysis - diagnosis - etiology - physiopathology ; Perioperative Care ; Pediatrics ; Muscular Dystrophy, Duchenne - complications - metabolism - physiopathology ; Malignant Hyperthermia - diagnosis - metabolism - physiopathology ; Intraoperative Complications - diagnosis - etiology - physiopathology ; Hyperkalemia - complications ; Humans ; Heart Arrest - complications - etiology ; Diagnosis, Differential ; Child, Preschool ; Child ; Anesthetics, Inhalation - adverse effects ; Anesthesia, Inhalation ; Adolescent
Keywords anesthesia ; Duchenne muscular dystrophy ; pediatrics ; rhabdomyolysis
Links
  1. MORRIS P., Duchenne muscular dystrophy: a challenge for the anaesthetist, 10.1046/j.1460-9592.1997.d01-41.x
  2. Silversides Candice K., Webb Gary D., Harris Vivien A., Biggar Douglas W., Effects of deflazacort on left ventricular function in patients with Duchenne muscular dystrophy, 10.1016/s0002-9149(02)03429-x
  3. Jenkins JG, Crit Care Med, 10, 645 (1982)
  4. Miller F, Dev Med Child Neurol, 34, 775 (1992)
  5. Almenrader N, Br J Anaesth, 97, 851 (2006)
  6. Schmidt G. N., Burmeister M.‐A., Lilje C., Wappler F., Bischoff P., Acute heart failure during spinal surgery in a boy with Duchenne muscular dystrophy, 10.1093/bja/aeg116
  7. Sethna NF, Anesthesiology, 68, 462 (1988)
  8. Shapiro F, Muscle Nerve, 15, 604 (1992)
  9. Kelfer HM, Pediatrics, 71, 118 (1983)
  10. Kleopa KA, Anesthesiology, 93, 1535 (2000)
  11. Oka S, Can Anaesth Soc J, 29, 627 (1982)
  12. ROSENBERG HENRY, HEIMAN-PATTERSON TERRY, Duchenneʼs Muscular Dystrophy and Malignant Hyperthermia : Another Warning, 10.1097/00000542-198310000-00020
  13. Zatz M, J Neurol Sci, 102, 190 (1991)
  14. Marchildon Michael B., Malignant Hyperthermia : Current Concepts, 10.1001/archsurg.1982.01380270063014
  15. Nathan Aruna, Ganesh Arjunan, Godinez Rodolfo I., Nicolson Susan C., Greeley William J., Hyperkalemic Cardiac Arrest After Cardiopulmonary Bypass in a Child with Unsuspected Duchenne Muscular Dystrophy : , 10.1213/01.ane.0000146533.21771.2f
  16. Bush Andrew, Dubowitz Victor, Fatal rhabdomyolysis complicating general anaesthesia in a child with Becker muscular dystrophy, 10.1016/0960-8966(91)90025-n
  17. Boba Antonio, Fatal postanesthetic complications in two muscular dystrophic patients, 10.1016/0022-3468(70)90523-3
  18. Sethna NF, Can Anaesth Soc J, 33, 799 (1986)
  19. Marks WA, J Child Neurol, 2, 160 (1987)
  20. CHALKIADIS G. A., BRANCH K. G., Cardiac arrest after isoflurane anaesthesia in a patient with Duchenne's muscular dystrophy, 10.1111/j.1365-2044.1990.tb14497.x
  21. GIRSHIN MICHAEL, MUKHERJEE JANA, CLOWNEY ROSS, SINGER LEWIS P., WASNICK JOHN, The postoperative cardiovascular arrest of a 5-year-old male: an initial presentation of Duchenne's muscular dystrophy1, 10.1111/j.1460-9592.2005.01698.x
  22. Rosenberg H, APSF Newsletter, 20, 31 (2005)
  23. Larsen UT, Can J Anaesth, 36, 418 (1989)
  24. Obata R, Can J Anaesth, 46, 564 (1999)
  25. RUBIANO REMICIO, CHANG JUEL-LING, CARROLL JOAN, SONBOLIAN NASSER, LARSON CHRISTOPHER E., Acute Rhabdomyolysis following Halothane Anesthesia without Succinylcholine : , 10.1097/00000542-198711000-00051
  26. Takahashi H, Masui, 51, 190 (2002)
  27. Tang TT, Acta Paediatr, 81, 716 (1992)
  28. Umino M, J Oral Maxillofac Surg, 47, 71 (1989)
  29. Wang JM, Can Anaesth Soc J, 33, 492 (1986)
  30. Larach Marilyn Green, Localio A Russell, Allen Gregory C., Denborough Michael A., Ellis F Richard, Gronert Gerald A., Kaplan Richard F., Muldoon Sheila M., Nelson Thomas E., Ørding Helle, Rosenberg Henry, Waud Barbara E., Wedel Denise J., A Clinical Grading Scale to Predict Malignant Hyperthermia Susceptibility : , 10.1097/00000542-199404000-00008
  31. Hirshman C. A., Dovnes H., Leon D., Bergman N. A., THE BASENJI-GREYHOUND (B G) DOG : A NEW MODEL OF REACTIVE AIRWAY DISEASE, 10.1097/00000542-198009001-00395
  32. Rosenberg Henry, Antognini Joseph F., Muldoon Sheila, Testing for Malignant Hyperthermia : , 10.1097/00000542-200201000-00036
  33. Fletcher JE, Anesthesiology, 90, 654 (1999)
  34. Takagi A, Rinsho Shinkeigaku, 40, 423 (2000)
  35. Heiman-Patterson TD, Pediatr Neurol, 2, 356 (1986)
  36. BUZELLO W., HUTTARSCH H., MUSCLE RELAXATION IN PATIENTS WITH DUCHENNE'S MUSCULAR DYSTROPHY : Use of Vecuronium in Two Patients, 10.1093/bja/60.2.228
  37. HEYTENS L., MARTIN J. J., VAN DE KELFT E., BOSSAERT L. L., IN VITROCONTRACTURE TESTS IN PATIENTS WITH VARIOUS NEUROMUSCULAR DISEASES, 10.1093/bja/68.1.72
  38. BROWNELL A. K. W., PAASUKE R. T., ELASH A., FOWLOW S. B., SEAGRAM C. G. F., DIEWOLD R. J., FRIESEN C., Malignant Hyperthermia in Duchenne Muscular Dystrophy : , 10.1097/00000542-198302000-00013
  39. Gronert Gerald A., Fowler William, Cardinet George H., Grix Arthur, Ellis William G., Schwartz Marshall Z., Absence of malignant hyperthermia contractures in Becker-Duchenne dystrophy at age 2, 10.1002/mus.880150110
  40. Krivosic-Horber R, Arch Fr Pediatr, 47, 421 (1990)
  41. Miller ED, ., Anesthesiology, 48, 146 (1978)
  42. Adnet PJ, Br J Anaesth, 72, 93 (1994)
  43. Mader N., Gilly H., Bittner R. E., Dystrophin deficient mdx muscle is not prone to MH susceptibility: an in vitro study, 10.1093/bja/79.1.125
  44. Boltshauser E, Br J Anaesth, 52, 559 (1980)
  45. Farrell PT, Anaesth Intensive Care, 22, 597 (1994)
  46. SMITH C. L., BUSH G. H., ANAESTHESIA AND PROGRESSIVE MUSCULAR DYSTROPHY, 10.1093/bja/57.11.1113
  47. Desmedt John E., Regeneration in Duchenne Muscular Dystrophy : Electromyographic Evidence, 10.1001/archneur.1976.00500090048010
  48. Willner J, Ital J Neurol Sci, 5, 117 (1984)
  49. YEMEN TERRY A., MCCLAIN CRAIG, Muscular dystrophy, anesthesia and the safety of inhalational agents revisited; again, 10.1111/j.1460-9592.2005.01801.x
  50. Richards WC, Anaesth Intensive Care, 1, 150 (1972)
  51. Mendell JR, J Child Neurol, 10, 150 (1995)
  52. Carlson C.George, The Dystrophinopathies: An Alternative to the Structural Hypothesis, 10.1006/nbdi.1998.0188
  53. Gronert Gerald A., Cardiac Arrest after Succinylcholine : Mortality Greater with Rhabdomyolysis Than Receptor Upregulation, 10.1097/00000542-200103000-00026
  54. Goresky GV, Can J Anaesth, 46, 525 (1999)
  55. Circulation, 112, IV-1 (2005)
  56. Bisogno JL, Crit Care Med, 22, 697 (1994)
  57. Hollmann MW, Eur J Anaesthesiol, 20, 606 (2003)
  58. Dunn JF, J Neurol Sci, 103, 226 (1991)
  59. Williams IA, Am J Physiol Heart Circ Physiol, 292, H846 (2007)
  60. Krause T., Gerbershagen M. U., Fiege M., Weißhorn R., Wappler F., Dantrolene ? A review of its pharmacology, therapeutic use and new developments, 10.1111/j.1365-2044.2004.03658.x
Bibliographic reference Hayes, Jason ; Veyckemans, Francis ; Bissonnette, Bruno. Duchenne muscular dystrophy: an old anesthesia problem revisited. In: Paediatric Anaesthesia, Vol. 18, no. 2, p. 100-6 (2008)
Permanent URL http://hdl.handle.net/2078.1/36907