Halleux, G.
Maréchal, Georges
[UCL]
Godfraind-De Becker, A.
[UCL]
Male NMRI mice 60 days old were submitted to a hypocaloric diet consisting in a 40% restriction of the mean spontaneous intake. They lost about 15% weight in 7-10 d; animals used for a longer term experimental (49 d) stabilized their weight. The myosin heavy chains (MHC) were separated by gel electrophoresis (SDS-PAGE 5%) and the proportion of the different MHC's was determined by densitometry of the gels. In extensor digitorum longus (EDL, a fast muscle) the proportion of MHC2A increased after 9 d caloric restriction and that the difference is still more apparent after 49 d. There is a slight non-significant increase of MHC2A in soleus, a slow muscle. Hypocaloric diet slows down markedly fast muscles (EDL) and moderately slow muscles (Soleus).
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Bibliographic reference |
Halleux, G. ; Maréchal, Georges ; Godfraind-De Becker, A.. Heavy chains of striated muscles myosins in NMRI mice on hypocaloric diet.Réunion de la Société belge de physiologie et de pharmacologie (Gent, 3/11/1990). In: Arch Int Physiol Biochim, Vol. 99, no.2, p. p34 (1991) |
Permanent URL |
http://hdl.handle.net/2078/288086 |