User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Intracardiac injection of T-61, a veterinary euthanasia drug.

Primary tabs

Hantson, Philippe [UCL] Semaan, Claude [UCL] Jouret, Jean-Claude [UCL] Rahier, Jacques [UCL] Lauwerys, Robert [UCL] Mahieu, Paul [UCL]

CASE REPORT: We report a suicidal attempt by intracardiac injection of T-61, a veterinary euthanasia drug containing embutramide, mebezonium and tetracaine in dimethylformamide. The main complications were reversible acute renal failure and pericardial effusion. There was a delayed abnormality of the liver function tests possibly related to the dimethylformamide solvent. A liver biopsy on day 16 showed a normal hepatic architecture with lipid-containing lysosomes and prominent vesicular endoplasmic reticulum noted on electron microscopy.

  1. Kingston R. L., J Toxicol Clin Toxicol, 15, 492 (1979)
  2. Cavaliere U., Minerva Anestesiol, 48, 861 (1982)
  3. Cordell William H, Curry Steven C, Brent Furbee R, Mitchell-Flynn David L, Veterinary euthanasia drugs as suicide agents, 10.1016/s0196-0644(86)80681-3
  4. Rodineau P., R6an Soins Intens Med Urg, 5, 203 (1989)
  5. NICOLAS FRAMÇOISE, RODINEAU PHILIPPE, ROUZIOUX JEAN-MARC, TACK IVAN, CHABAC SYLVIE, MERAM DALITH, Fulminant hepatic failure in poisoning due to ingestion of T 61, a veterinary euthanasia drug : , 10.1097/00003246-199005000-00021
  6. Redlich C. A., Gastroenterology, 99, 748 (1990)
  7. REDLICH CARRIE A., Liver Disease Associated with Occupational Exposure to the Solvent Dimethylformamide, 10.7326/0003-4819-108-5-680
  8. Trevisani Franco, Tam� Maria Rosa, Bernardi Mauro, Tovoli Cristina, Gasbarrini Antonio, Panarelli Marzia, Gasbarrini Giovanni, Severe hepatic failure occurring with T61 ingestion in an attempted suicide : Early recovery with the use of intravenous infusion of reduced glutathione, 10.1007/bf01316810
  9. Scailteur Veronique, Lauwerys R.R., Dimethylformamide (DMF) hepatotoxicity, 10.1016/0300-483x(87)90082-5
Bibliographic reference Hantson, Philippe ; Semaan, Claude ; Jouret, Jean-Claude ; Rahier, Jacques ; Lauwerys, Robert ; et. al. Intracardiac injection of T-61, a veterinary euthanasia drug.. In: Journal of toxicology. Clinical toxicology, Vol. 34, no. 2, p. 235-239 (1996)
Permanent URL http://hdl.handle.net/2078.1/28401