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Imidazoles and benzoyl peroxide: a comparative trial of two treatment schedules.

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Van Neste, D Tennstedt, Dominique [UCL] Decroix, J.

A double-blind, split-face, self-controlled pilot trial was designed for comparing the therapeutical effect of (a) combination of 2% miconazole nitrate and 5% benzoyl peroxide applied twice daily and (b) topical application of 1% isoconazole nitrate in the morning followed in the evening by 5% benzoyl peroxide. There were no clinically relevant differences between both treatment regimes. These results are interpreted in terms of bioavailability of the active substances.

Document type Article de périodique (Journal article) – Clinical Trial, Comparative Study, Controlled Clinical Trial, Journal Article
Publication date 1986
Language Anglais
Journal information "Dermatologica" - Vol. 172, no. 2, p. 108-12 (1986)
issn 0011-9075
Publication status Publié
Affiliation UCL - (SLuc) Service de dermatologie
MESH Subject Acne Vulgaris - drug therapy ; Administration, Topical ; Adolescent ; Adult ; Benzoyl Peroxide - therapeutic use ; Clinical Trials as Topic ; Double-Blind Method ; Drug Administration Schedule ; Drug Therapy, Combination ; Female ; Humans ; Imidazoles - therapeutic use ; Male ; Miconazole - analogs & derivatives - therapeutic use ; Peroxides - therapeutic use ; Random Allocation
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Bibliographic reference Van Neste, D ; Tennstedt, Dominique ; Decroix, J.. Imidazoles and benzoyl peroxide: a comparative trial of two treatment schedules.. In: Dermatologica, Vol. 172, no. 2, p. 108-12 (1986)
Permanent URL http://hdl.handle.net/2078.1/27990