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Immunologic tolerance to skin allograft after graft-versus-host disease.

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Elias, Badwi Georges [UCL] Meunier, Daniel [UCL] Squifflet, Jean Paul [UCL] Marot, Liliane [UCL] Weynand, Birgit [UCL] Vanwijck, Romain [UCL] Bayet, Bénédicte [UCL]

We report the observation of a young girl suffering from acute myeloid luekemia who developed chronic graft-versus-host disease with major skin involvement after a bone marrow graft from her histocompatible brother. She developed an immunologic tolerance to her brother's skin, which was used to correct the severe joint contractures, sequelae of the graft-versus-host disease.

Document type Article de périodique (Journal article) – Article de recherche – Case Reports, Journal Article
Access type Accès restreint
Publication date 2007
Language Anglais
Journal information "Plastic and Reconstructive Surgery" - Vol. 119, no. 3, p. 40e-44e (2007)
Peer reviewed yes
Publisher Lippincott, Williams & Wilkins (Hagerstown (United States))
issn 0032-1052
e-issn 1529-4242
Publication status Publié
Affiliations UCL - MD/MNOP - Département de morphologie normale et pathologique
UCL - MD/CHIR - Département de chirurgie
UCL - (SLuc) Service de chirurgie plastique
UCL - (SLuc) Service de chirurgie et transplantation abdominale
UCL - (SLuc) Service de dermatologie
UCL - (SLuc) Service d'anatomie pathologique
UCL - MD/MINT - Département de médecine interne
MESH Subject Acute Disease ; Adolescent ; Bone Marrow Transplantation - adverse effects ; Contracture - etiology - surgery ; Female ; Graft vs Host Disease - complications - immunology ; Humans ; Immune Tolerance ; Leukemia, Myeloid - therapy ; Male ; Skin - immunology ; Skin Diseases - etiology - immunology ; Skin Transplantation - immunology ; Transplantation Tolerance ; Transplantation, Homologous
Links
Bibliographic reference Elias, Badwi Georges ; Meunier, Daniel ; Squifflet, Jean Paul ; Marot, Liliane ; Weynand, Birgit ; et. al. Immunologic tolerance to skin allograft after graft-versus-host disease.. In: Plastic and Reconstructive Surgery, Vol. 119, no. 3, p. 40e-44e (2007)
Permanent URL http://hdl.handle.net/2078.1/26305