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14C-Propoxyphene demethylation in the rat : An example of differences between liver and intestinal drug-presystemic metabolism
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Document type | Article de périodique (Journal article) – Article de recherche |
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Access type | Accès restreint |
Publication date | 1997 |
Journal information | "Drug Metabolism and Disposition : the biological fate of chemicals" - Vol. 25, no. 11, p. 1257-1259 (1997) |
Peer reviewed | yes |
Publisher | American Society for Pharmacology and Experimental Therapeutics |
issn | 0090-9556 |
e-issn | 1521-009X |
Publication status | Publié |
Affiliations |
UCL
- MD/MINT - Département de médecine interne UCL - (SLuc) Service d'hépato-gastro-entérologie UCL - (SLuc) Service de chirurgie cardiovasculaire et thoracique UCL - (SLuc) Service de médecine nucléaire |
MESH Subject | Analgesics, Opioid - pharmacokinetics ; Animals ; Area Under Curve ; Biotransformation ; Dealkylation ; Dextropropoxyphene - pharmacokinetics ; Hepatectomy ; Intestines - metabolism ; Liver - metabolism ; Male ; Microsomes, Liver - metabolism ; Rats ; Rats, Wistar |
Links |
Bibliographic reference | Horsmans, Yves ; Saliez, Alain ; van den Berge, Véronique ; Desager, Jean-Pierre ; Geubel, André ; et. al. 14C-Propoxyphene demethylation in the rat : An example of differences between liver and intestinal drug-presystemic metabolism. In: Drug Metabolism and Disposition : the biological fate of chemicals, Vol. 25, no. 11, p. 1257-1259 (1997) |
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Permanent URL | http://hdl.handle.net/2078.1/23038 |