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Targeting Carbohydrates and Polyphenols for a Healthy Microbiome and Healthy Weight.

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Van Hul, Matthias [UCL] Cani, Patrice D. [UCL]

PURPOSE OF REVIEW: In this review, we focus on microbiota modulation using non-digestible carbohydrate and polyphenols (i.e., prebiotics) that have the potential to modulate body weight. RECENT FINDINGS: Prebiotics derived from plants have gained the interest of public and scientific communities as they may prevent diseases and help maintain health. Maintaining a healthy body weight is key to reducing the risk of developing chronic metabolic complications. However, the prevalence of obesity has increased to pandemic proportions and is now ranked globally in the top five risk factors for death. While diet and behavioral modification programs aiming to reduce weight gain and promote weight loss are effective in the short term, they remain insufficient over the long haul as compliance is often low and weight regain is very common. As a result, novel dietary strategies targeting the gut microbiota have been successful in decreasing obesity and metabolic disorders via different molecular mechanisms.

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès libre
Publication date 2019
Language Anglais
Journal information "Current nutrition reports" - Vol. 8, no. 4, p. 307-316 (2019)
Peer reviewed yes
Publisher Springer US ((United States) New York, NY)
e-issn 2161-3311
Publication status Publié
Affiliation UCL - SSS/LDRI - Louvain Drug Research Institute
Keywords Dietary fibers ; Gut microbiota ; Obesity ; Polyphenols ; Prebiotics
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Bibliographic reference Van Hul, Matthias ; Cani, Patrice D.. Targeting Carbohydrates and Polyphenols for a Healthy Microbiome and Healthy Weight.. In: Current nutrition reports, Vol. 8, no. 4, p. 307-316 (2019)
Permanent URL http://hdl.handle.net/2078.1/218917