Mechanically-assisted and non-invasive ventilation: Innovative step forward in the motion management

Van Ooteghem, Geneviève [UCL] Dasnoy-Sumell, Damien [UCL] Lemaire, Guillaume [UCL] Liistro, Giuseppe [UCL] Sterpin, Edmond [UCL] Geets, Xavier [UCL]

Purpose or Objective : Management of breathing-related motion remains challenging. Current strategies rely either on dedicated margins (ITV, MidPosition) that result in futile irradiation of normal tissues, or on respiratory-synchronized techniques that are highly sensitive to changes in breathing pattern and technologically exacting. Therefore, mechanically-assisted and non-invasive ventilation (MANIV) could be used on unsedated patients to impose regular breathing and reproducible tumour motion, but also to modulate the breathing pattern for motion mitigation techniques. We investigated the feasibility of MANIV on volunteers, and its impact on internal motion. [...]