Fagoo, M.
Godfraind, Theophile
[UCL]
This study was undertaken to characterize endogenous digitalis-like activity in water extract from mammalian tissues. Prepurified samples obtained from guinea-pig heart were analysed by reverse-phase HPLC using an acetonitrile gradient. The eluent was assayed for its activity as inhibitor of human heart Na+, K+-ATPase and digoxin-like immunoreactivity. Both activities were recovered in the same fraction after two successive chromatographic steps. These results provide further evidence for the presence of an endogenous digitalis-like factor, cardiodigin, in mammalian heart.
- Kramer Herbert J., Natriuretic hormone — A circulating inhibitor of sodium- and potassium-activated adenosine triphesphatase : Its potential role in body fluid and blood pressure regulation, 10.1007/bf01747753
- De Wardener H. E., THE NATRIURETIC HORMONE, 10.1113/expphysiol.1982.sp002651
- Castan̂eda-Hernandez G., Godfraind T., Effect of High Sodium Intake on Tissue Distribution of Endogenous Digitalis-Like Material in the Rat, 10.1042/cs0660225
- Godfraind, Arch. Int. Pharmacodyn. Ther., 258, 165 (1982)
- Godfraind T., Castañeda-Hernández G., Ghysel-Burton J., De Pover A., Hypothesis for the Mechanism of Stimulation of the Na/K Pump by Cardiac Glycosides—Role of Endogenous Digitalis-Like Factor, Current Topics in Membranes and Transport (1983) ISBN:9780121533199 p.913-915, 10.1016/s0070-2161(08)60650-4
- De Pover Alain, Endogenous digitalis-like factor and inotropic receptor sites in rat heart, 10.1016/0014-2999(84)90149-3
- DE WARDENER H. E., MACGREGOR G. A., The Relation of a Circulating Sodium Transport Inhibitor (the Natriuretic Hormone?) to Hypertension : , 10.1097/00005792-198309000-00004
- Buckalew V M, Gruber K A, Natriuretic Hormone, 10.1146/annurev.ph.46.030184.002015
- Haddy F. J., The Role of a Humoral Na+, K+-ATPase Inhibitor in Regulating Precapillary Vessel Tone : , 10.1097/00005344-198406002-00019
- De Pover Alain, Castañeda-Hernández Gilberto, Godfraind Théophile, Water versus acetone-HCl extraction of digitalis-like factor from guinea-pig heart, 10.1016/0006-2952(82)90224-6
- Godfraind Théophile, De Pover Alain, Verbeke Norbert, Influence of pH and sodium on the inhibition of guinie-pig heart (Na+ + K+)-ATPase by calcium, 10.1016/0005-2744(77)90152-8
- Bais Renze, A rapid and sensitive radiometric assay for adenosine triphosphatase activity using Cerenkov radiation, 10.1016/0003-2697(75)90215-8
- Plasma Digitalis-like Factor(s) Increase with Salt Loading, 10.1056/nejm198312083092316
- GRAVES STEVEN W., An Endogenous Digoxin-Like Substance in Patients with Renal Impairment, 10.7326/0003-4819-99-5-604
- Gruber Kenneth A., Whitaker Janice M., Buckalew Vardaman M., Endogenous digitalis-like substance in plasma of volume-expanded dogs, 10.1038/287743a0
- Crabos M., Wainer I.W., Cloix J.F., Measurement of endogenous Na+,K+-ATPase inhibitors in human plasma and urine using high-performance liquid chromatography, 10.1016/0014-5793(84)80946-1
- Kojima Itaru, Circulating digitalis-like substance is increased in doca-salt hypertension, 10.1016/0006-291x(84)90449-2
- Hicks Jocelyn M., Brett Elaine M., Falsely Increased Digoxin Concentrations in Samples from Neonates and Infants : , 10.1097/00007691-198412000-00015
- Klingmüller D., Weiler E., Kramer H. J., Digoxin-like natriuretic activity in the urine of salt loaded healthy subjects, 10.1007/bf01716732
- CHRISTIANSEN C., RØDBRO P., CHRISTENSEN MERETE S., HARTNACK BIRGITTE, IS 1,25-DIHYDROXY-CHOLECALCIFEROL HARMFUL TO RENAL FUNCTION IN PATIENTS WITH CHRONIC RENAL FAILURE?, 10.1111/j.1365-2265.1981.tb00659.x
- Hamlyn John M., Ringel Richard, Schaeffer Juergen, Levinson Paul D., Hamilton Bruce P., Kowarski A. Avinoam, Blaustein Mordecai P., A circulating inhibitor of (Na+ + K+) ATPase associated with essential hypertension, 10.1038/300650a0
- Capps, Pharmacy Int., 5, 12 (1984)
- Capps, Pharmacy Int., 5, 292 (1984)
- Soldin S.J., Papanastasiou-Diamandi A., Heyes J., Lingwood C., Olley P., Are immunoassays for digoxin reliable?, 10.1016/s0009-9120(84)90637-4
- Soldin S.J., Papanastasiou-Diamandi A., Heyes J., Lingwood C., Olley P., Are immunoassays for digoxin reliable?, 10.1016/s0009-9120(84)90637-4
- Vinge, N. Engl. J. Med., 310, 725 (1984)
- Whitmer Kyra R., Wallick Earl T., Epps Dennis E., Lane Lois K., Collins John H., Schwartz Arnold, Effects of extracts of rat brain on the digitalis receptor, 10.1016/0024-3205(82)90253-3
- Kracke, J. Lab. Clin. Rev., 101, 105 (1983)
Bibliographic reference |
Fagoo, M. ; Godfraind, Theophile. Further characterization of cardiodigin, Na+, K+-ATPase inhibitor extracted from mammalian tissues.. In: FEBS letters, Vol. 184, no. 1, p. 150-4 (1985) |
Permanent URL |
http://hdl.handle.net/2078.1/21805 |