User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Current immunogenetic predisposition to tuberculosis in the Moroccan population.

Primary tabs

Qrafli, Mounia Najimi, Mustapha [UCL] Elaouad, Rajae Sadki, Khalid

Tuberculosis (TB) is a serious infectious disease that kills approximately two million people per year, particularly in low- and middle-income countries. Numerous genetic epidemiology studies have been conducted of many ethnic groups worldwide and have highlighted the critical impact of the genetic environment on TB distribution. Many candidate genes associated with resistance or susceptibility to TB have been identified. In Morocco, where TB is still a major public health problem, various observations of clinical, microbiological and incidence distribution are heavily affected by genetic background and external environment. Morocco has almost the same clinical profile as do other North African countries, mainly the increase in more extrapulmonary than pulmonary forms of the diseases, when compared to European, Asian or American populations. In addition, a linkage analysis study that examined Moroccan TB patients identified a unique chromosome region that had a strong association with the risk of contracting TB. Other genes in the Moroccan population that were found to be associated seem to be involved predominantly in modulating the innate immunity. In this review, we appraise the major candidate genes that have been reported in Moroccan immunogenetic studies and discuss their updated role in TB, particularly during the first phase of the immune response to Mycobacterium tuberculosis (Mtb) infection.

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès restreint
Publication date 2017
Language Anglais
Journal information "International Journal of Immunogenetics" - Vol. 44, no.6, p. 286-304 (2017)
Peer reviewed yes
Publisher Wiley-Blackwell Publishing Ltd. ((United Kingdom) Oxford)
issn 1744-3121
e-issn 1744-313X
Publication status Publié
Affiliations UCL - SSS/IREC/PEDI - Pôle de Pédiatrie
UCL - (SLuc) Service de gastro-entérologie et hépatologie pédiatrique
Keywords Moroccan ; immunogenetic ; tuberculosis
Links
  1. Abel Laurent, Sánchez Fabio O., Oberti Jean, Thuc Nguyen V., Van Hoa Le, Lap Vu D., Skamene Emil, Lagrange Philippe H., Schurr Erwin, Susceptibility to Leprosy Is Linked to the HumanNRAMP1Gene, 10.1086/513830
  2. Aderem Alan, Ulevitch Richard J., Toll-like receptors in the induction of the innate immune response, 10.1038/35021228
  3. Adorini Luciano, Intervention in autoimmunity: The potential of vitamin D receptor agonists, 10.1016/j.cellimm.2005.04.013
  4. Akira Shizuo, Uematsu Satoshi, Takeuchi Osamu, Pathogen Recognition and Innate Immunity, 10.1016/j.cell.2006.02.015
  5. Amirzargar, European Cytokine Network, 17, 84 (2006)
  6. Anand, Journal of Microbiology, Immunology, and Infection, 41, 17 (2008)
  7. Arbour Nancy C., Lorenz Eva, Schutte Brian C., Zabner Joseph, Kline Joel N., Jones Michael, Frees Kathy, Watt Janet L., Schwartz David A., TLR4 mutations are associated with endotoxin hyporesponsiveness in humans, 10.1038/76048
  8. Haque Shafiul, Mandal RajuK, Panda AdityaK, Areeshi MohammedY, Akhter Naseem, Evaluating the association between taqi variant of vitamin D receptor gene and susceptibility to tuberculosis: A meta-analysis, 10.4103/0971-6580.139791
  9. Arji Naima, Busson Marc, Iraqi Ghali, Bourkadi Jamal Eddine, Benjouad Abdelaziz, Bouayad Abdellatif, Mariaselvam Christina, Salah Sofiane, Fortier Catherine, Amokrane Kahina, Marzais François, Boukouaci Wahid, Krishnamoorthy Rajagopal, Charron Dominique, El Aouad Rajae, Tamouza Ryad, Genetic diversity of TLR2, TLR4, and VDR loci and pulmonary tuberculosis in Moroccan patients, 10.3855/jidc.3820
  10. Arji, Journal of Infection in Developing Countries, 6, 73 (2012)
  11. Ates O., Dolek B., Dalyan L., Musellim B., Ongen G., Topal-Sarikaya A., The association between BsmI variant of vitamin D receptor gene and susceptibility to tuberculosis, 10.1007/s11033-010-0404-8
  12. Awandare Gordon A., Martinson Jeremy J., Were Tom, Ouma Collins, Davenport Gregory C., Ong’echa John M., Wang Wenkui, Leng Lin, Ferrell Robert E., Bucala Richard, Perkins Douglas J., MIF(Macrophage Migration Inhibitory Factor) Promoter Polymorphisms and Susceptibility to Severe Malarial Anemia, 10.1086/600894
  13. Azad Abul K., Sadee Wolfgang, Schlesinger Larry S., Innate Immune Gene Polymorphisms in Tuberculosis, 10.1128/iai.00443-12
  14. Babb C., van der Merwe L., Beyers N., Pheiffer C., Walzl G., Duncan K., van Helden P., Hoal E.G., Vitamin D receptor gene polymorphisms and sputum conversion time in pulmonary tuberculosis patients, 10.1016/j.tube.2007.03.001
  15. Baeke Femke, Takiishi Tatiana, Korf Hannelie, Gysemans Conny, Mathieu Chantal, Vitamin D: modulator of the immune system, 10.1016/j.coph.2010.04.001
  16. Baghdadi Jamila El, Orlova Marianna, Alter Andrea, Ranque Brigitte, Chentoufi Mohamed, Lazrak Faouzia, Archane Moulay Idriss, Casanova Jean-Laurent, Benslimane Abdellah, Schurr Erwin, Abel Laurent, An autosomal dominant major gene confers predisposition to pulmonary tuberculosis in adults, 10.1084/jem.20060269
  17. Baker A. R., McDonnell D. P., Hughes M., Crisp T. M., Mangelsdorf D. J., Haussler M. R., Pike J. W., Shine J., O'Malley B. W., Cloning and expression of full-length cDNA encoding human vitamin D receptor., 10.1073/pnas.85.10.3294
  18. Banchereau Jacques, Steinman Ralph M., Dendritic cells and the control of immunity, 10.1038/32588
  19. Banoei Mohammad Mehdi, Mirsaeidi Mehdi Seyed, Houshmand Massoud, Tabarsi Payam, Ebrahimi Golnaz, Zargari Laleh, Kashani Baharak Houshiar, Masjedi Mohammad Reza, Mansouri Seyed Davood, Ramirez Julio, Vitamin D receptor homozygote mutant tt and bb are associated with susceptibility to pulmonary tuberculosis in the Iranian population, 10.1016/j.ijid.2009.05.001
  20. Barreiro Luis B, Neyrolles Olivier, Babb Chantal L, Tailleux Ludovic, Quach Hélène, McElreavey Ken, Helden Paul D. van, Hoal Eileen G, Gicquel Brigitte, Quintana-Murci Lluis, Promoter Variation in the DC-SIGN–Encoding Gene CD209 Is Associated with Tuberculosis, 10.1371/journal.pmed.0030020
  21. Barton, Journal of Leukocyte Biology, 66, 757 (1999)
  22. Batten Marcel, Ghilardi Nico, The biology and therapeutic potential of interleukin 27, 10.1007/s00109-007-0164-7
  23. Begovich Ann B., Carlton Victoria E.H., Honigberg Lee A., Schrodi Steven J., Chokkalingam Anand P., Alexander Heather C., Ardlie Kristin G., Huang Qiqing, Smith Ashley M., Spoerke Jill M., Conn Marion T., Chang Monica, Chang Sheng-Yung P., Saiki Randall K., Catanese Joseph J., Leong Diane U., Garcia Veronica E., McAllister Linda B., Jeffery Douglas A., Lee Annette T., Batliwalla Franak, Remmers Elaine, Criswell Lindsey A., Seldin Michael F., Kastner Daniel L., Amos Christopher I., Sninsky John J., Gregersen Peter K., A Missense Single-Nucleotide Polymorphism in a Gene Encoding a Protein Tyrosine Phosphatase (PTPN22) Is Associated with Rheumatoid Arthritis, 10.1086/422827
  24. Bellamy R., Beyers N., McAdam K. P. W. J., Ruwende C., Gie R., Samaai P., Bester D., Meyer M., Corrah T., Collin M., Camidge D. R., Wilkinson D., Hoal-van Helden E., Whittle H. C., Amos W., van Helden P., Hill A. V. S., Genetic susceptibility to tuberculosis in Africans: A genome-wide scan, 10.1073/pnas.140201897
  25. Bellamy R., Ruwende C., Corrah T., McAdam K. P. W. J., Thursz M., Whittle H. C., Hill A. V. S., Tuberculosis and Chronic Hepatitis B Virus Infection in Africans and Variation in the Vitamin D Receptor Gene, 10.1086/314614
  26. Bellamy Richard, Ruwende Cyril, Corrah Tumani, McAdam Keith P.W.J., Whittle Hilton C., Hill Adrian V.S., Variations in theNRAMP1Gene and Susceptibility to Tuberculosis in West Africans, 10.1056/nejm199803053381002
  27. Ben-Ali, Clinical and Diagnostic Laboratory Immunology, 11, 625 (2004)
  28. Ben-Ali Meriem, Barreiro Luis B., Chabbou Abdellatif, Haltiti Raja, Braham Ezzeddine, Neyrolles Olivier, Dellagi Koussay, Gicquel Brigitte, Quintana-Murci Lluis, Barbouche Mohamed-Ridha, Promoter and neck region length variation of DC-SIGN is not associated with susceptibility to tuberculosis in Tunisian patients, 10.1016/j.humimm.2007.09.003
  29. Ben-Selma Walid, Harizi Hedi, Boukadida Jalel, MCP-1 −2518 A/G functional polymorphism is associated with increased susceptibility to active pulmonary tuberculosis in Tunisian patients, 10.1007/s11033-011-0695-4
  30. Ben-Selma Walid, Harizi Hedi, Letaief Mahmoud, Boukadida Jalel, Age- and gender-specific effects on NRAMP1 gene polymorphisms and risk of the development of active tuberculosis in Tunisian populations, 10.1016/j.ijid.2011.11.016
  31. Bernhagen J., Calandra T., Mitchell R. A., Martin S. B., Tracey K. J., Voelter W., Manogue K. R., Cerami A., Bucala R., MIF is a pituitary-derived cytokine that potentiates lethal endotoxaemia, 10.1038/365756a0
  32. Biswas Debasis, Gupta Shailendra K, Sindhwani Girish, Patras Abhishek, TLR2 polymorphisms, Arg753Gln and Arg677Trp, are not associated with increased burden of tuberculosis in Indian patients, 10.1186/1756-0500-2-162
  33. Bloom B. R., Bennett B., Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity, 10.1126/science.153.3731.80
  34. Boechat Antonio Luiz, Ogusku Mauricio Morishi, Sadahiro Aya, dos Santos Maria Cristina, Association between the PTPN22 1858C/T gene polymorphism and tuberculosis resistance, 10.1016/j.meegid.2013.02.019
  35. Boisson-Dupuis Stéphanie, El Baghdadi Jamila, Parvaneh Nima, Bousfiha Aziz, Bustamante Jacinta, Feinberg Jacqueline, Samarina Arina, Grant Audrey V., Janniere Lucile, El Hafidi Naima, Hassani Amal, Nolan Daniel, Najib Jilali, Camcioglu Yildiz, Hatipoglu Nevin, Aydogmus Cigdem, Tanir Gonul, Aytekin Caner, Keser Melike, Somer Ayper, Aksu Guside, Kutukculer Necil, Mansouri Davood, Mahdaviani Alireza, Mamishi Setareh, Alcais Alexandre, Abel Laurent, Casanova Jean-Laurent, IL-12Rβ1 Deficiency in Two of Fifty Children with Severe Tuberculosis from Iran, Morocco, and Turkey, 10.1371/journal.pone.0018524
  36. Bornman Liza, Campbell Sarah J., Fielding Katherine, Bah Boubacar, Sillah Jackson, Gustafson Per, Manneh Kebba, Lisse Ida, Allen Angela, Sirugo Giorgio, Sylla Aissatou, Aaby Peter, McAdam Keith P. W. J., Bah‐Sow Oumou, Bennett Steve, Lienhardt Christian, Hill Adrian V. S., Vitamin D Receptor Polymorphisms and Susceptibility to Tuberculosis in West Africa: A Case‐Control and Family Study, 10.1086/424462
  37. von Both Ulrich, Kaforou Myrsini, Levin Michael, Newton Sandra M., Understanding immune protection against tuberculosis using RNA expression profiling, 10.1016/j.vaccine.2015.05.025
  38. Bottini Nunzio, Musumeci Lucia, Alonso Andres, Rahmouni Souad, Nika Konstantina, Rostamkhani Masoud, MacMurray James, Meloni Gian Franco, Lucarelli Paola, Pellecchia Maurizio, Eisenbarth George S, Comings David, Mustelin Tomas, A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes, 10.1038/ng1323
  39. Calandra Thierry, Bernhagen Jürgen, Metz Christine N., Spiegel Lori A., Bacher Michael, Donnelly Thomas, Cerami Anthony, Bucala Richard, MIF as a glucocorticoid-induced modulator of cytokine production, 10.1038/377068a0
  40. Calandra T., The macrophage is an important and previously unrecognized source of macrophage migration inhibitory factor, 10.1084/jem.179.6.1895
  41. Cellier M., Human natural resistance-associated macrophage protein: cDNA cloning, chromosomal mapping, genomic organization, and tissue-specific expression, 10.1084/jem.180.5.1741
  42. Chang Kai, Deng Shaoli, Lu Weiping, Wang Feng, Jia Shuangrong, Li Fake, Yu Lili, Chen Ming, Association between CD209 -336A/G and -871A/G Polymorphisms and Susceptibility of Tuberculosis: A Meta-Analysis, 10.1371/journal.pone.0041519
  43. Chen, Sichuan Da Xue Xue Bao Yi Xue Ban, 37, 847 (2006)
  44. Chen R., Wang J., Tang S-W., Zhang Y., Lv X-Z., Wu S-S., Yang Z-R., Xia Y-Y., Chen D-F., Zhan S-Y., CYP7A1, BAAT and UGT1A1 polymorphisms and susceptibility to anti-tuberculosis drug-induced hepatotoxicity, 10.5588/ijtld.15.0450
  45. Cherni Lotfi, Pakstis Andrew J., Boussetta Sami, Elkamel Sarra, Frigi Sabeh, Khodjet-El-Khil Houssein, Barton Alison, Haigh Eva, Speed William C., Ben Ammar Elgaaied Amel, Kidd Judith R., Kidd Kenneth K., Genetic variation in Tunisia in the context of human diversity worldwide : NORTH AFRICA-DISTINCT GENETIC REGION, 10.1002/ajpa.23008
  46. Chu S-F, Tam C M, Wong H S, Kam K M, Lau Y L, Chiang A K S, Association between RANTES functional polymorphisms and tuberculosis in Hong Kong Chinese, 10.1038/sj.gene.6364412
  47. Cobat A., Orlova M., Barrera L.F., Schurr E., Host Genomics and Control of Tuberculosis Infection, 10.1159/000341499
  48. Cohen Jonathan C., Cali James J., Jelinek Diane F., Mehrabian Margarete, Sparkes Robert S., Lusis Aldons J., Russell David W., Hobbs Helen H., Cloning of the human cholesterol 7α-hydroxylase gene (CYP7) and localization to chromosome 8q11–q12, 10.1016/s0888-7543(05)80298-8
  49. Cohen, Blood, 93, 2013 (1999)
  50. Cooper, Immunology, 84, 423 (1995)
  51. Coudray , C. Torroni , A. Achilli , A. Pala , M. Olivieri , A. Larrouy , G. Dugoujon , J.-M. 2009 Les lignées mitochondriales et l'histoire génétique des populations berbérophones du nord de l'Afrique 63 72
  52. Covert M. W., Achieving Stability of Lipopolysaccharide-Induced NF- B Activation, 10.1126/science.1112304
  53. van Crevel Reinout, Parwati Ida, Sahiratmadja Edhyana, Marzuki Sangkot, Ottenhoff Tom H. M., Netea Mihai G., van der Ven Andre, Nelwan Ronald H., van der Meer Jos W., Alisjahbana Bachti, van de Vosse Esther, Infection withMycobacterium tuberculosisBeijing Genotype Strains Is Associated with Polymorphisms inSLC11A1/NRAMP1in Indonesian Patients with Tuberculosis, 10.1086/648477
  54. Criswell Lindsey A., Pfeiffer Kirsten A., Lum Raymond F., Gonzales Bonnie, Novitzke Jill, Kern Marlena, Moser Kathy L., Begovich Ann B., Carlton Victoria E.H., Li Wentian, Lee Annette T., Ortmann Ward, Behrens Timothy W., Gregersen Peter K., Analysis of Families in the Multiple Autoimmune Disease Genetics Consortium (MADGC) Collection: the PTPN22 620W Allele Associates with Multiple Autoimmune Phenotypes, 10.1086/429096
  55. Dabrowski Marek P., Peel William E., Thomson Alasdair E. R., Plasma membrane cholesterol regulates human lymphocyte cytotoxic function, 10.1002/eji.1830101105
  56. Das R., Koo M.-S., Kim B. H., Jacob S. T., Subbian S., Yao J., Leng L., Levy R., Murchison C., Burman W. J., Moore C. C., Scheld W. M., David J. R., Kaplan G., MacMicking J. D., Bucala R., Macrophage migration inhibitory factor (MIF) is a critical mediator of the innate immune response to Mycobacterium tuberculosis, 10.1073/pnas.1301128110
  57. David J. R., Delayed hypersensitivity in vitro: its mediation by cell-free substances formed by lymphoid cell-antigen interaction., 10.1073/pnas.56.1.72
  58. Delgado Julio C., Baena Andres, Thim Sok, Goldfeld Anne E., Ethnic‐Specific Genetic Associations with Pulmonary Tuberculosis, 10.1086/344891
  59. DeLuca Hector F, History of the discovery of vitamin D and its active metabolites, 10.1038/bonekey.2013.213
  60. Deniz Omer, Gumus Seyfettin, Yaman Halil, Ciftci Faruk, Ors Fatih, Cakir Erdinc, Tozkoparan Ergun, Bilgic Hayati, Ekiz Kudret, Serum total cholesterol, HDL-C and LDL-C concentrations significantly correlate with the radiological extent of disease and the degree of smear positivity in patients with pulmonary tuberculosis, 10.1016/j.clinbiochem.2006.10.015
  61. Deshmane Satish L., Kremlev Sergey, Amini Shohreh, Sawaya Bassel E., Monocyte Chemoattractant Protein-1 (MCP-1): An Overview, 10.1089/jir.2008.0027
  62. Diaz-Gallo L., Gourh P., Broen J., Simeon C., Fonollosa V., Ortego-Centeno N., Agarwal S., Vonk M., Coenen M., Riemekasten G., Hunzelmann N., Hesselstrand R., Tan F., Reveille J., Assassi S., Garcia-Hernandez F., Carreira P., Camps M., Fernandez-Nebro A., de la Pena P. G., Nearney T., Hilda D., Gonzalez-Gay M., Airo P., Beretta L., Scorza R., Herrick A., Worthington J., Pros A., Gomez-Gracia I., Trapiella L., Espinosa G., Castellvi I., Witte T., de Keyser F., Vanthuyne M., Mayes M., Radstake T., Arnett F., Martin J., Rueda B., Analysis of the influence of PTPN22 gene polymorphisms in systemic sclerosis, 10.1136/ard.2010.130138
  63. Donn Rachelle, Alourfi Zaynab, De Benedetti Fabrizio, Meazza Cristina, Zeggini Eleftheria, Lunt Mark, Stevens Adam, Shelley Emma, Lamb Rebecca, Ollier William E. R., Thomson Wendy, Ray David, , Mutation screening of the macrophage migration inhibitory factor gene: Positive association of a functional polymorphism of macrophage migration inhibitory factor with juvenile idiopathic arthritis, 10.1002/art.10492
  64. Baghdadi, The International Journal of Tuberculosis and Lung Disease, 7, 599 (2003)
  65. Feng W-X., Flores-Villanueva P. O., Mokrousov I., Wu X-R., Xiao J., Jiao W-W., Sun L., Miao Q., Shen C., Shen D., Liu F., Jia Z-W., Shen A., CCL2−2518 (A/G) polymorphisms and tuberculosis susceptibility: a meta-analysis [Review article], 10.5588/ijtld.11.0205
  66. Fernández-Mestre Mercedes, Villasmil Ángel, Takiff Howard, Fuentes Alcalá Zhenia, NRAMP1andVDRGene Polymorphisms in Susceptibility to Tuberculosis in Venezuelan Population, 10.1155/2015/860628
  67. Ferrari Giorgio, Langen Hanno, Naito Makoto, Pieters Jean, A Coat Protein on Phagosomes Involved in the Intracellular Survival of Mycobacteria, 10.1016/s0092-8674(00)80754-0
  68. Filipe-Santos Orchidée, Bustamante Jacinta, Chapgier Ariane, Vogt Guillaume, de Beaucoudrey Ludovic, Feinberg Jacqueline, Jouanguy Emmanuelle, Boisson-Dupuis Stéphanie, Fieschi Claire, Picard Capucine, Casanova Jean-Laurent, Inborn errors of IL-12/23- and IFN-γ-mediated immunity: molecular, cellular, and clinical features, 10.1016/j.smim.2006.07.010
  69. Flores-Villanueva Pedro O., Ruiz-Morales Jorge A., Song Chang-Hwa, Flores Ludmila M., Jo Eun-Kyeong, Montaño Marta, Barnes Peter F., Selman Moises, Granados Julio, A functional promoter polymorphism inmonocyte chemoattractant protein–1is associated with increased susceptibility to pulmonary tuberculosis, 10.1084/jem.20050126
  70. Flynn, Journal of Immunology, 155, 2515 (1995)
  71. Fu Lingyu, Zhao Yanyan, Wu Xiaomei, Liu Hong, Shi Jingpu, Lu Jingyu, Zhou Bo, CYP7A1 genotypes and haplotypes associated with hypertension in an obese Han Chinese population, 10.1038/hr.2011.18
  72. Ganachari Malathesha, Ruiz-Morales Jorge A., Gomez de la Torre Pretell Juan C., Dinh Jeffrey, Granados Julio, Flores-Villanueva Pedro O., Joint Effect of MCP-1 Genotype GG and MMP-1 Genotype 2G/2G Increases the Likelihood of Developing Pulmonary Tuberculosis in BCG-Vaccinated Individuals, 10.1371/journal.pone.0008881
  73. Gazouli Maria, Atsaves Vassilios, Mantzaris Gerassimos, Economou Michalis, Nasioulas George, Evangelou Konstantinos, Archimandritis Athanassios J., Anagnou Nicholas P., Role of functional polymorphisms of NRAMP1 gene for the development of Crohnʼs disease : , 10.1002/ibd.20488
  74. Geijtenbeek Teunis B.H, Torensma Ruurd, van Vliet Sandra J, van Duijnhoven Gerard C.F, Adema Gosse J, van Kooyk Yvette, Figdor Carl G, Identification of DC-SIGN, a Novel Dendritic Cell–Specific ICAM-3 Receptor that Supports Primary Immune Responses, 10.1016/s0092-8674(00)80693-5
  75. Geijtenbeek Teunis B.H., van Vliet Sandra J., Koppel Estella A., Sanchez-Hernandez Marta, Vandenbroucke-Grauls Christine M.J.E., Appelmelk Ben, van Kooyk Yvette, Mycobacteria Target DC-SIGN to Suppress Dendritic Cell Function, 10.1084/jem.20021229
  76. Gibney K. B., MacGregor L., Leder K., Torresi J., Marshall C., Ebeling P. R., Biggs B.-A., Vitamin D Deficiency Is Associated with Tuberculosis and Latent Tuberculosis Infection in Immigrants from Sub-Saharan Africa, 10.1086/525268
  77. Goldsack Lisa, Kirman Joanna R., Half-truths and selective memory: Interferon gamma, CD4+ T cells and protective memory against tuberculosis, 10.1016/j.tube.2007.07.001
  78. Gomez Luis M., Anaya Juan-Manuel, Martin Javier, Genetic Influence of PTPN22 R620W Polymorphism in Tuberculosis, 10.1016/j.humimm.2005.11.008
  79. Gómez Luis M., Anaya Juan-Manuel, Sierra-Filardi Elena, Cadena Jose, Corbí Ángel, Martín Javier, Analysis of DC-SIGN (CD209) Functional Variants in Patients with Tuberculosis, 10.1016/j.humimm.2006.07.003
  80. Gómez L. M., Sánchez E., Ruiz-Narvaez E. A., López-Nevot M. A., Anaya J.-M., Martín J., Macrophage migration inhibitory factor gene influences the risk of developing tuberculosis in northwestern Colombian population, 10.1111/j.1399-0039.2007.00843.x
  81. Gonzalez E., Rovin B. H., Sen L., Cooke G., Dhanda R., Mummidi S., Kulkarni H., Bamshad M. J., Telles V., Anderson S. A., Walter E. A., Stephan K. T., Deucher M., Mangano A., Bologna R., Ahuja S. S., Dolan M. J., Ahuja S. K., HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels, 10.1073/pnas.202357499
  82. Gregersen Peter K, Gaining insight into PTPN22 and autoimmunity, 10.1038/ng1205-1300
  83. Gruenheid Samantha, Pinner Elhanan, Desjardins Michel, Gros Philippe, Natural Resistance to Infection with Intracellular Pathogens: TheNramp1Protein Is Recruited to the Membrane of the Phagosome, 10.1084/jem.185.4.717
  84. Hackam David J., Rotstein Ori D., Zhang Wei-jian, Gruenheid Samantha, Gros Philippe, Grinstein Sergio, Host Resistance to Intracellular Infection: Mutation of Natural Resistance-associated Macrophage Protein 1 (Nramp1) Impairs Phagosomal Acidification, 10.1084/jem.188.2.351
  85. Hagiwara Tomoko, Kono Suminori, Yin Guang, Toyomura Kengo, Nagano Jun, Mizoue Tetsuya, Mibu Ryuichi, Tanaka Masao, Kakeji Yoshihiro, Maehara Yoshihiko, Okamura Takeshi, Ikejiri Kouji, Futami Kitaroh, Yasunami Youichi, Maekawa Takafumi, Takenaka Kenji, Ichimiya Hitoshi, Imaizumi Nobutoshi, Genetic Polymorphism in CytochromeP450 7A1 and Risk of Colorectal Cancer: The Fukuoka Colorectal Cancer Study, 10.1158/0008-5472.can-04-3872
  86. Hashemi, EXCLI Journal, 14, 117 (2015)
  87. Heiniger H. J., Marshall J. D., Cholesterol synthesis in polyclonally activated cytotoxic lymphocytes and its requirement for differentiation and proliferation., 10.1073/pnas.79.12.3823
  88. Henn Brenna M., Botigué Laura R., Gravel Simon, Wang Wei, Brisbin Abra, Byrnes Jake K., Fadhlaoui-Zid Karima, Zalloua Pierre A., Moreno-Estrada Andres, Bertranpetit Jaume, Bustamante Carlos D., Comas David, Genomic Ancestry of North Africans Supports Back-to-Africa Migrations, 10.1371/journal.pgen.1002397
  89. Hermiston Michelle L., Xu Zheng, Majeti Ravindra, Weiss Arthur, Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases, 10.1172/jci0214794
  90. Hill R, The lymphoid protein tyrosine phosphatase Lyp interacts with the adaptor molecule Grb2 and functions as a negative regulator of T-cell activation, 10.1016/s0301-472x(01)00794-9
  91. Hofman M K, Groenendijk M, Verkuijlen P J J H, Jonkers I J A M, Mohrschladt M F, Smelt A H M, Princen H M G, Modulating effect of the A-278C promoter polymorphism in the cholesterol 7alpha-hydroxylase gene on serum lipid levels in normolipidaemic and hypertriglyceridaemic individuals, 10.1038/sj.ejhg.5201236
  92. Hsieh C., Macatonia S., Tripp C., Wolf S., O'Garra A, Murphy K., Development of TH1 CD4+ T cells through IL-12 produced by Listeria-induced macrophages, 10.1126/science.8097338
  93. Hu Y F, Luscher B, Admon A, Mermod N, Tjian R, Transcription factor AP-4 contains multiple dimerization domains that regulate dimer specificity., 10.1101/gad.4.10.1741
  94. Hudson J. D., A Proinflammatory Cytokine Inhibits p53 Tumor Suppressor Activity, 10.1084/jem.190.10.1375
  95. Hussein Yousri M., Awad Hanan A., Shalaby Sally M., Ali Al-Shaymaa A., Alzahrani Saad S., Toll-like receptor 2 and Toll-like receptor 4 polymorphisms and susceptibility to asthma and allergic rhinitis: A case–control analysis, 10.1016/j.cellimm.2012.02.006
  96. Jafari Mohammad, Nasiri Mohammad Reza, Sanaei Roozbeh, Anoosheh Saber, Farnia Parisa, Sepanjnia Adel, Tajik Nader, The NRAMP1, VDR, TNF-α, ICAM1, TLR2 and TLR4 gene polymorphisms in Iranian patients with pulmonary tuberculosis: A case–control study, 10.1016/j.meegid.2016.01.013
  97. Jamieson S E, Miller E N, Black G F, Peacock C S, Cordell H J, Howson J M M, Shaw M-A, Burgner D, Xu W, Lins-Lainson Z, Shaw J J, Ramos F, Silveira F, Blackwell J M, Evidence for a cluster of genes on chromosome 17q11–q21 controlling susceptibility to tuberculosis and leprosy in Brazilians, 10.1038/sj.gene.6364029
  98. Jepson A., Fowler A., Banya W., Singh M., Bennett S., Whittle H., Hill A. V. S., Genetic Regulation of Acquired Immune Responses to Antigens of Mycobacterium tuberculosis: a Study of Twins in West Africa, 10.1128/iai.69.6.3989-3994.2001
  99. Jo Eun-Kyeong, Mycobacterial interaction with innate receptors: TLRs, C-type lectins, and NLRs : , 10.1097/qco.0b013e3282f88b5d
  100. Joosten S A, Goeman J J, Sutherland J S, Opmeer L, de Boer K G, Jacobsen M, Kaufmann S H E, Finos L, Magis-Escurra C, Ota M O C, Ottenhoff T H M, Haks M C, Identification of biomarkers for tuberculosis disease using a novel dual-color RT–MLPA assay, 10.1038/gene.2011.64
  101. Joshi L., Ponnana M., Penmetsa S. R., Nallari P., Valluri V., Gaddam S., Serum Vitamin D Levels and VDR Polymorphisms (BsmI and FokI) in Patients and their Household Contacts Susceptible to Tuberculosis, 10.1111/sji.12127
  102. KALLMANN FRANZ J., REISNER DAVID, TWIN STUDIES ON GENETIC VARIATIONS IN RESISTANCE TO TUBERCULOSIS, 10.1093/oxfordjournals.jhered.a105302
  103. Kang Seung H., Abdel-Massih Rima C., Brown Robert A., Dierkhising Ross A., Kremers Walter K., Razonable Raymund R., Homozygosity for the Toll-Like Receptor 2 R753Q Single-Nucleotide Polymorphism Is a Risk Factor for Cytomegalovirus Disease After Liver Transplantation, 10.1093/infdis/jir819
  104. Kawai T, Akira S, TLR signaling, 10.1038/sj.cdd.4401850
  105. Kawai T., Takeuchi O., Fujita T., Inoue J.-i., Muhlradt P. F., Sato S., Hoshino K., Akira S., Lipopolysaccharide Stimulates the MyD88-Independent Pathway and Results in Activation of IFN-Regulatory Factor 3 and the Expression of a Subset of Lipopolysaccharide-Inducible Genes, 10.4049/jimmunol.167.10.5887
  106. Kettaneh, The International Journal of Tuberculosis and Lung Disease, 10, 717 (2006)
  107. Khader Shabaana A, Bell Guy K, Pearl John E, Fountain Jeffrey J, Rangel-Moreno Javier, Cilley Garth E, Shen Fang, Eaton Sheri M, Gaffen Sarah L, Swain Susan L, Locksley Richard M, Haynes Laura, Randall Troy D, Cooper Andrea M, IL-23 and IL-17 in the establishment of protective pulmonary CD4+ T cell responses after vaccination and during Mycobacterium tuberculosis challenge, 10.1038/ni1449
  108. Kim Mi-Jeong, Wainwright Helen C., Locketz Michael, Bekker Linda-Gail, Walther Gabriele B., Dittrich Corneli, Visser Annalie, Wang Wei, Hsu Fong-Fu, Wiehart Ursula, Tsenova Liana, Kaplan Gilla, Russell David G., Caseation of human tuberculosis granulomas correlates with elevated host lipid metabolism : Lipid metabolism in human tuberculous granulomas, 10.1002/emmm.201000079
  109. Kindt Nadège, Preillon Julie, Kaltner Herbert, Gabius Hans-Joachim, Chevalier Dominique, Rodriguez Alexandra, Johnson Bryon D., Megalizzi Véronique, Decaestecker Christine, Laurent Guy, Saussez Sven, Macrophage migration inhibitory factor in head and neck squamous cell carcinoma: clinical and experimental studies, 10.1007/s00432-013-1375-7
  110. Kirenga Bruce J, Ssengooba Willy, Muwonge Catherine, Nakiyingi Lydia, Kyaligonza Stephen, Kasozi Samuel, Mugabe Frank, Boeree Martin, Joloba Moses, Okwera Alphonse, Tuberculosis risk factors among tuberculosis patients in Kampala, Uganda: implications for tuberculosis control, 10.1186/s12889-015-1376-3
  111. Kobayashi K., Yuliwulandari R., Yanai H., Naka I., Lien L. T., Hang N. T. L., Hijikata M., Keicho N., Tokunaga K., Association of TLR polymorphisms with development of tuberculosis in Indonesian females, 10.1111/j.1399-0039.2011.01821.x
  112. van Kooyk Yvette, Geijtenbeek Teunis B. H., DC-SIGN: escape mechanism for pathogens, 10.1038/nri1182
  113. Kouhpayeh H.-R., Hashemi M., Hashemi S.-A., Moazeni-Roodi A., Naderi M., Sharifi-Mood B., Taheri M., Mohammadi M., Ghavami S., R620W functional polymorphism of protein tyrosine phosphatase non-receptor type 22 is not associated with pulmonary tuberculosis in Zahedan, southeast Iran, 10.4238/2012.april.27.6
  114. Krockenberger, Anticancer Research, 32, 5233 (2012)
  115. Kroner Juliana, Sommer Andrea, Fabri Mario, Vitamin D Every Day to Keep the Infection Away?, 10.3390/nu7064170
  116. Kuai Shou-Gang, Ou Qin-Fang, You De-Hong, Shang Zhong-Bo, Wang Jun, Liu Jun, Zhou Xi-Ke, Pei Hao, Huang Li-Hua, Functional polymorphisms in the gene encoding macrophage migration inhibitory factor (MIF) are associated with active pulmonary tuberculosis, 10.3109/23744235.2015.1107188
  117. Kyogoku Chieko, Ortmann Ward A., Lee Annette, Selby Scott, Carlton Victoria E.H., Chang Monica, Ramos Paula, Baechler Emily C., Batliwalla Franak M., Novitzke Jill, Williams Adrienne H., Gillett Clarence, Rodine Peter, Graham Robert R., Ardlie Kristin G., Gaffney Patrick M., Moser Kathy L., Petri Michelle, Begovich Ann B., Gregersen Peter K., Langefeld Carl D., Behrens Timothy W., Genetic Association of the R620W Polymorphism of Protein Tyrosine Phosphatase PTPN22 with Human SLE, 10.1086/423790
  118. Lai Yung-Fa, Lin Tsun-Mei, Wang Chiou-Huey, Su Pei-Yi, Wu Jiun-Ting, Lin Meng-Chih, Eng Hock-Liew, Functional polymorphisms of the TLR7 and TLR8 genes contribute to Mycobacterium tuberculosis infection, 10.1016/j.tube.2016.03.008
  119. Lambrinoudaki Irene V., Kaparos George I., Vlachou Sofia A., Stamatelopoulos Kimon S., Georgiopoulos George A., Sergentanis Thodoris N., Panoulis Constantinos P., Christodoulakos George E., Alexandrou Andreas P., Kouskouni Evangelia E., Creatsa Maria G., Papamichael Christos M., CYP A-204C polymorphism is associated with subclinical atherosclerosis in postmenopausal women : , 10.1097/gme.0b013e31817727c3
  120. Lamsyah H., Rueda B., Baassi L., Elaouad R., Bottini N., Sadki K., Martin J., Association ofPTPN22gene functional variants with development of pulmonary tuberculosis in Moroccan population, 10.1111/j.1399-0039.2009.01304.x
  121. Lang P. O., Samaras N., Samaras D., Aspinall R., How important is vitamin D in preventing infections?, 10.1007/s00198-012-2204-6
  122. Lee Shih-Wei, Chuang Tzu-Yi, Huang Hsiu-Han, Liu Chi-Wei, Kao Yung-Hsi, Wu Lawrence Shih-Hsin, VDR and VDBP genes polymorphisms associated with susceptibility to tuberculosis in a Han Taiwanese population, 10.1016/j.jmii.2015.12.008
  123. Lee Y.H., Song G.G., Vitamin D receptor gene FokI, TaqI, BsmI, and ApaI polymorphisms and susceptibility to pulmonary tuberculosis: a meta-analysis, 10.4238/2015.august.7.21
  124. Leech Michelle, Lacey Derek, Xue Jin Rong, Santos Leilani, Hutchinson Paul, Wolvetang Ernst, David John R., Bucala Richard, Morand Eric F., Regulation of p53 by macrophage migration inhibitory factor in inflammatory arthritis, 10.1002/art.11165
  125. Leifer Cynthia A., Medvedev Andrei E., Molecular mechanisms of regulation of Toll-like receptor signaling, 10.1189/jlb.2mr0316-117rr
  126. Lewis, The International Journal of Tuberculosis and Lung Disease, 9, 1174 (2005)
  127. Li XiangWei, Yang Yu, Zhou Feng, Zhang Yunzhi, Lu Hongzhou, Jin Qi, Gao Lei, SLC11A1 (NRAMP1) Polymorphisms and Tuberculosis Susceptibility: Updated Systematic Review and Meta-Analysis, 10.1371/journal.pone.0015831
  128. Li Yanlin, Yuan Tao, Lu Weiping, Chen Ming, Cheng Xiaoxing, Deng Shaoli, Association of tuberculosis and polymorphisms in the promoter region of macrophage migration inhibitory factor (MIF) in a Southwestern China Han population, 10.1016/j.cyto.2012.06.010
  129. Li Yanlin, Zeng Zhaofang, Deng Shaoli, Study of the relationship between human MIF level, MIF-794CATT5-8 microsatellite polymorphism, and susceptibility of tuberculosis in Southwest China, 10.1016/j.bjid.2012.06.018
  130. Liang Bin, Guo Yang, Li Yunhui, Kong Hong, Association between IL-10 Gene Polymorphisms and Susceptibility of Tuberculosis: Evidence Based on a Meta-Analysis, 10.1371/journal.pone.0088448
  131. Liaw, The International Journal of Tuberculosis and Lung Disease, 6, 454 (2002)
  132. Lin Yi-Tzu, Verma Amanda, P. Hodgkinson Conrad, Toll-Like Receptors and Human Disease: Lessons from Single Nucleotide Polymorphisms, 10.2174/138920212803759712
  133. Liu, The International Journal of Tuberculosis and Lung Disease, 8, 428 (2004)
  134. Liu Aihua, Li Jing, Bao Fukai, Zhu Ziwei, Feng Shi, Yang Jiaru, Wang Lin, Shi Mei, Wen Xia, Zhao Hua, Voravuthikunchai Supayang P., Single nucleotide polymorphisms in cytokine MIF gene promoter region are closely associated with human susceptibility to tuberculosis in a southwestern province of China, 10.1016/j.meegid.2015.12.003
  135. Liu Guoyuan, Li Guanghua, Xu Ying, Song Na, Shen Suqin, Jiang Deke, Zeng Wenjiao, Wang Honghai, Association between IL12B polymorphisms and tuberculosis risk: A meta-analysis, 10.1016/j.meegid.2013.12.008
  136. Liu P. T., Toll-Like Receptor Triggering of a Vitamin D-Mediated Human Antimicrobial Response, 10.1126/science.1123933
  137. Lombard Zane, Dalton Desiré-Lee, Venter Philip A., Williams Robert C., Bornman Liza, Association of HLA-DR, -DQ, and Vitamin D Receptor Alleles and Haplotypes with Tuberculosis in the Venda of South Africa, 10.1016/j.humimm.2006.04.008
  138. Lue H, Thiele M, Franz J, Dahl E, Speckgens S, Leng L, Fingerle-Rowson G, Bucala R, Lüscher B, Bernhagen J, Macrophage migration inhibitory factor (MIF) promotes cell survival by activation of the Akt pathway and role for CSN5/JAB1 in the control of autocrine MIF activity, 10.1038/sj.onc.1210318
  139. Ma Xin, Liu Yuhua, Gowen Brian B., Graviss Edward A., Clark Andrew G., Musser James M., Full-Exon Resequencing Reveals Toll-Like Receptor Variants Contribute to Human Susceptibility to Tuberculosis Disease, 10.1371/journal.pone.0001318
  140. Ma Xin, Reich Robert A., Gonzalez Omar, Pan Xi, Fothergill Amanda K., Starke Jeffery R., Teeter Larry D., Musser James M., Graviss Edward A., No Evidence for Association between the Polymorphism in the 3′ Untranslated Region of Interleukin‐12B and Human Susceptibility to Tuberculosis, 10.1086/378674
  141. Ma Mai-juan, Xie Lan-pin, Wu Shu-cai, Tang Fang, Li Hao, Zhang Zheng-shan, Yang Hong, Chen Su-li, Liu Ning, Liu Wei, Cao Wu-chun, Toll-like receptors, tumor necrosis factor–α, and interleukin-10 gene polymorphisms in risk of pulmonary tuberculosis and disease severity, 10.1016/j.humimm.2010.07.009
  142. Malik S., Abel L., Tooker H., Poon A., Simkin L., Girard M., Adams G. J., Starke J. R., Smith K. C., Graviss E. A., Musser J. M., Schurr E., Alleles of the NRAMP1 gene are risk factors for pediatric tuberculosis disease, 10.1073/pnas.0503368102
  143. Manetti R., Natural killer cell stimulatory factor (interleukin 12 [IL-12]) induces T helper type 1 (Th1)-specific immune responses and inhibits the development of IL-4-producing Th cells, 10.1084/jem.177.4.1199
  144. Medhi, The Indian Journal of Medical Research, 134, 200 (2011)
  145. Medvedev Andrei E., Toll-Like Receptor Polymorphisms, Inflammatory and Infectious Diseases, Allergies, and Cancer, 10.1089/jir.2012.0140
  146. Menard Laurence, Saadoun David, Isnardi Isabelle, Ng Yen-Shing, Meyers Greta, Massad Christopher, Price Christina, Abraham Clara, Motaghedi Roja, Buckner Jane H., Gregersen Peter K., Meffre Eric, The PTPN22 allele encoding an R620W variant interferes with the removal of developing autoreactive B cells in humans, 10.1172/jci45790
  147. Merza Muayad, Farnia Parissa, Anoosheh Sabar, Varahram Mohammed, Kazampour Mehdi, Pajand Omid, Saeif Shima, Mirsaeidi Mehdi, Masjedi Mohammad Reza, Velayati Ali Akbar, Hoffner Sven, The NRAMPI, VDR and TNF-α gene polymorphisms in Iranian tuberculosis patients: the study on host susceptibility, 10.1590/s1413-86702009000400002
  148. Meyer Christian G., Thye Thorsten, Host genetic studies in adult pulmonary tuberculosis, 10.1016/j.smim.2014.09.005
  149. MIAO RUIFEN, LI JIEQUAN, SUN ZHAOPING, LI CHEN, XU FEI, Association between the CD209 promoter −336A/G polymorphism and susceptibility to tuberculosis: A meta-analysis : CD209 polymorphism and tuberculosis risk, 10.1111/j.1440-1843.2012.02185.x
  150. Mishra Gunja, Poojary Satish S., Raj Prithvi, Tiwari Pramod Kumar, Genetic polymorphisms of CCL2, CCL5, CCR2 and CCR5 genes in Sahariya tribe of North Central India: An association study with pulmonary tuberculosis, 10.1016/j.meegid.2012.03.018
  151. Mitchell R. A., Liao H., Chesney J., Fingerle-Rowson G., Baugh J., David J., Bucala R., Macrophage migration inhibitory factor (MIF) sustains macrophage proinflammatory function by inhibiting p53: Regulatory role in the innate immune response, 10.1073/pnas.012511599
  152. Mizue Y., Ghani S., Leng L., McDonald C., Kong P., Baugh J., Lane S. J., Craft J., Nishihira J., Donnelly S. C., Zhu Z., Bucala R., Role for macrophage migration inhibitory factor in asthma, 10.1073/pnas.0507189102
  153. Möller Marlo, Nebel Almut, van Helden Paul D, Schreiber Stefan, Hoal Eileen G, Analysis of eight genes modulating interferon gamma and human genetic susceptibility to tuberculosis: a case-control association study, 10.1186/1471-2334-10-154
  154. Morris Gerard A. J., Edwards Digna R. Velez, Hill Philip C., Wejse Christian, Bisseye Cyrille, Olesen Rikke, Edwards Todd L., Gilbert John R., Myers Jamie L., Stryjewski Martin E., Abbate Eduardo, Estevan Rosa, Hamilton Carol D., Tacconelli Alessandra, Novelli Giuseppe, Brunetti Ercole, Aaby Peter, Sodemann Morten, Østergaard Lars, Adegbola Richard, Williams Scott M., Scott William K., Sirugo Giorgio, Interleukin 12B (IL12B) Genetic Variation and Pulmonary Tuberculosis: A Study of Cohorts from The Gambia, Guinea-Bissau, United States and Argentina, 10.1371/journal.pone.0016656
  155. Murphy E. E., B7 and interleukin 12 cooperate for proliferation and interferon gamma production by mouse T helper clones that are unresponsive to B7 costimulation, 10.1084/jem.180.1.223
  156. Mustelin Tomas, Protein tyrosine phosphorylation in T cell signaling, 10.2741/a821
  157. Naderi Mohammad, Hashemi Mohammad, Taheri Mohsen, Pesarakli Hossein, Eskandari-Nasab Ebrahim, Bahari Gholamreza, CD209 promoter –336 A/G (rs4804803) polymorphism is associated with susceptibility to pulmonary tuberculosis in Zahedan, southeast Iran, 10.1016/j.jmii.2013.03.013
  158. Narasimhan Padmanesan, Wood James, MacIntyre Chandini Raina, Mathai Dilip, Risk Factors for Tuberculosis, 10.1155/2013/828939
  159. Naruse Kuniko, Ueno Miki, Satoh Takaaki, Nomiyama Hisayuki, Tei Hajime, Takeda Masaharu, Ledbetter David H., Coillie Els Van, Opdenakker Ghislain, Gunge Norio, Sakaki Yoshiyuki, Iio Masayoshi, Miura Retsu, A YAC Contig of the Human CC Chemokine Genes Clustered on Chromosome 17q11.2, 10.1006/geno.1996.0274
  160. Nnoaham K. E, Clarke A., Low serum vitamin D levels and tuberculosis: a systematic review and meta-analysis, 10.1093/ije/dym247
  161. Noshiro Mitsuhide, Okuda Kyuichiro, Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7α-hydroxylase, 10.1016/0014-5793(90)80992-r
  162. Nugraha, The Southeast Asian Journal of Tropical Medicine and Public Health, 42, 338 (2011)
  163. Oddo M., Calandra T., Bucala R., Meylan P. R. A., Macrophage Migration Inhibitory Factor Reduces the Growth of Virulent Mycobacterium tuberculosis in Human Macrophages, 10.1128/iai.73.6.3783-3786.2005
  164. Ogarkov Oleg, Mokrousov Igor, Sinkov Viacheslav, Zhdanova Svetlana, Antipina Svetlana, Savilov Eugeniy, ‘Lethal’ combination of Mycobacterium tuberculosis Beijing genotype and human CD209 −336G allele in Russian male population, 10.1016/j.meegid.2011.10.005
  165. Ogus A.C., Yoldas B., Ozdemir T., Uguz A., Olcen S., Keser I., Coskun M., Cilli A., Yegin O., The Arg753Gln polymorphism of the human Toll-like receptor 2 gene in tuberculosis disease, 10.1183/09031936.03.00061703
  166. Olesen R, Wejse C, Velez D R, Bisseye C, Sodemann M, Aaby P, Rabna P, Worwui A, Chapman H, Diatta M, Adegbola R A, Hill P C, Østergaard L, Williams S M, Sirugo G, DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans, 10.1038/sj.gene.6364410
  167. ORAL H, BUDAK F, UZASLAN E, BASTURK B, BEKAR A, AKALIN H, EGE E, ENER B, GORAL G, Interleukin-10 (IL-10) gene polymorphism as a potential host susceptibility factor in tuberculosis, 10.1016/j.cyto.2006.07.015
  168. Pérez-Guzmán Carlos, Vargas Mario H., Hypocholesterolemia: A major risk factor for developing pulmonary tuberculosis?, 10.1016/j.mehy.2005.12.041
  169. Pérez-Guzmán Carlos, Vargas Mario H., Quiñonez Francisco, Bazavilvazo Norma, Aguilar Adriana, A Cholesterol-Rich Diet Accelerates Bacteriologic Sterilization in Pulmonary Tuberculosis, 10.1378/chest.127.2.643
  170. Pullinger Clive R., Eng Celeste, Salen Gerald, Shefer Sarah, Batta Ashok K., Erickson Sandra K., Verhagen Andrea, Rivera Christopher R., Mulvihill Sean J., Malloy Mary J., Kane John P., Human cholesterol 7α-hydroxylase (CYP7A1) deficiency has a hypercholesterolemic phenotype, 10.1172/jci0215387
  171. Qrafli Mounia, Amar Youssef, Bourkadi Jamaleddine, Amor Jouda Ben, Iraki Ghali, Bakri Youssef, Amzazi Saaîd, Lahlou Ouafae, Seghrouchni Fouad, Aouad Rajae El, Sadki Khalid, The CYP7A1 gene rs3808607 variant is associated with susceptibility of tuberculosis in Moroccan population, 10.11604/pamj.2014.18.1.3397
  172. Radstake Timothy R. D. J., Sweep Fred C. G. J., Welsing Paco, Franke Barbara, Vermeulen Sita H. H. M., Geurts-Moespot Anneke, Calandra Thierry, Donn Rachelle, van Riel Piet L. C. M., Correlation of rheumatoid arthritis severity with the genetic functional variants and circulating levels of macrophage migration inhibitory factor, 10.1002/art.21285
  173. Ravikumar M., Dheenadhayalan V., Rajaram K., Shanmuga Lakshmi S., Paul Kumaran P., Paramasivan C.N., Balakrishnan K., Pitchappan R.M., Associations of HLA-DRB1, DQB1 and DPB1 alleles with pulmonary tuberculosis in south India, 10.1054/tuld.1999.0213
  174. Remus Natascha, El Baghdadi Jamila, Fieschi Claire, Feinberg Jacqueline, Quintin Thibaut, Chentoufi Mohamed, Schurr Erwin, Benslimane Abdellah, Casanova Jean‐Laurent, Abel Laurent, Association ofIL12RB1Polymorphisms with Pulmonary Tuberculosis in Adults in Morocco, 10.1086/422534
  175. Rhee Inmoo, Veillette André, Protein tyrosine phosphatases in lymphocyte activation and autoimmunity, 10.1038/ni.2246
  176. RICHARD VINCENT, KINDT NADÈGE, SAUSSEZ SVEN, Macrophage migration inhibitory factor involvement in breast cancer (Review), 10.3892/ijo.2015.3185
  177. Rieck M., Arechiga A., Onengut-Gumuscu S., Greenbaum C., Concannon P., Buckner J. H., Genetic Variation in PTPN22 Corresponds to Altered Function of T and B Lymphocytes, 10.4049/jimmunol.179.7.4704
  178. Ritterhouse L. L., Crowe S. R., Niewold T. B., Kamen D. L., Macwana S. R., Roberts V. C., Dedeke A. B., Harley J. B., Scofield R. H., Guthridge J. M., James J. A., Vitamin D deficiency is associated with an increased autoimmune response in healthy individuals and in patients with systemic lupus erythematosus, 10.1136/ard.2010.148494
  179. Rockett, Infection and Immunity, 66, 5314 (1998)
  180. Roger Thierry, Chanson Anne-Laure, Knaup-Reymond Marlies, Calandra Thierry, Macrophage migration inhibitory factor promotes innate immune responses by suppressing glucocorticoid-induced expression of mitogen-activated protein kinase phosphatase-1, 10.1002/eji.200535413
  181. Roger Thierry, David John, Glauser Michel P., Calandra Thierry, MIF regulates innate immune responses through modulation of Toll-like receptor 4, 10.1038/414920a
  182. Roger Thierry, Glauser Michel P., Calandra Thierry, Macrophage migration inhibitory factor (MIF) modulates innate immune responses induced by endotoxin and Gram-negative bacteria, 10.1177/09680519010070061101
  183. Rossouw Manda, Nel Hendrik J, Cooke Graham S, van Helden Paul D, Hoal Eileen G, Association between tuberculosis and a polymorphic NFκB binding site in the interferon γ gene, 10.1016/s0140-6736(03)13491-5
  184. Roth Daniel E., Soto Giselle, Arenas Fanny, Bautista Christian T., Ortiz Jaime, Rodriguez Richard, Cabrera Lilia, Gilman Robert H., Association between Vitamin D Receptor Gene Polymorphisms and Response to Treatment of Pulmonary Tuberculosis, 10.1086/423212
  185. Ryu, The International Journal of Tuberculosis and Lung Disease, 4, 577 (2000)
  186. Sabri Ayoub, Grant Audrey V., Cosker Kristel, El Azbaoui Safa, Abid Ahmed, Abderrahmani Rhorfi Ismail, Souhi Hicham, Janah Hicham, Alaoui-Tahiri Kebir, Gharbaoui Yasser, Benkirane Majid, Orlova Marianna, Boland Anne, Deswarte Caroline, Migaud Melanie, Bustamante Jacinta, Schurr Erwin, Boisson-Dupuis Stephanie, Casanova Jean-Laurent, Abel Laurent, El Baghdadi Jamila, Association Study of Genes Controlling IL-12-dependent IFN-γ Immunity: STAT4 Alleles Increase Risk of Pulmonary Tuberculosis in Morocco, 10.1093/infdis/jiu140
  187. Sadki Khalid, Lamsyah Hoda, Rueda Blanca, Akil ELmahfoud, Sadak Abderrahim, Martin Javier, El Aouad Rajae, Analysis of MIF, FCGR2A and FCGR3A gene polymorphisms with susceptibility to pulmonary tuberculosis in Moroccan population, 10.1016/s1673-8527(09)60044-8
  188. Sadki, International Journal of Human Genetics, 9, 239 (2009)
  189. SALIMI SAEEDEH, FARAJIAN-MASHHADI FARZANEH, ALAVI-NAINI ROYA, TALEBIAN GOLBARG, NAROOIE-NEJAD MEHRNAZ, Association between vitamin D receptor polymorphisms and haplotypes with pulmonary tuberculosis, 10.3892/br.2014.402
  190. Schurz Haiko, Daya Michelle, Möller Marlo, Hoal Eileen G., Salie Muneeb, TLR1, 2, 4, 6 and 9 Variants Associated with Tuberculosis Susceptibility: A Systematic Review and Meta-Analysis, 10.1371/journal.pone.0139711
  191. Schwarz Margrit, Lund Erik G., Russell David W., Two 7α‐hydroxylase enzymes in bile acid biosynthesis : , 10.1097/00041433-199804000-00006
  192. Searle, Journal of Cell Science, 111, 2855 (1998)
  193. Selvaraj P., Alagarasu K., Harishankar M., Vidyarani M., Nisha Rajeswari D., Narayanan P.R., Cytokine gene polymorphisms and cytokine levels in pulmonary tuberculosis, 10.1016/j.cyto.2008.04.011
  194. Selvaraj P., Alagarasu K., Swaminathan S., Harishankar M., Narendran G., CD209 gene polymorphisms in South Indian HIV and HIV-TB patients, 10.1016/j.meegid.2008.12.003
  195. Serbina Natalya V., Jia Ting, Hohl Tobias M., Pamer Eric G., Monocyte-Mediated Defense Against Microbial Pathogens, 10.1146/annurev.immunol.26.021607.090326
  196. Shaw M A, Clayton D, Atkinson S E, Williams H, Miller N, Sibthorpe D, Blackwell J M, Linkage of rheumatoid arthritis to the candidate gene NRAMP1 on 2q35., 10.1136/jmg.33.8.672
  197. Shi G.L., Yang L., Sun Y., Yin Y.J., Song C.X., MCP-1 gene polymorphisms in North Chinese patients with pulmonary tuberculosis, 10.4238/2015.april.27.18
  198. da Silva Ronaldo Celerino, Segat Ludovica, da Cruz Heidi Lacerda Alves, Schindler Haiana Charifker, Montenegro Lilian Maria Lapa, Crovella Sergio, Guimarães Rafael Lima, Association of CD209 and CD209L polymorphisms with tuberculosis infection in a Northeastern Brazilian population, 10.1007/s11033-014-3416-y
  199. Singh A., Gaughan J.P., Kashyap V.K., SLC11A1 and VDR gene variants and susceptibility to tuberculosis and disease progression in East India, 10.5588/ijtld.11.0089
  200. Søborg Christian, Andersen Aase B., Madsen Hans O., Kok‐Jensen Axel, Skinhøj Peter, Garred Peter, Natural Resistance–Associated Macrophage Protein 1 Polymorphisms Are Associated with Microscopy‐Positive Tuberculosis, 10.1086/341775
  201. Søborg Christian, Andersen Aase Bengaard, Range Nyagosya, Malenganisho Wabyahe, Friis Henrik, Magnussen Pascal, Temu Mansuet M., Changalucha John, Madsen Hans O., Garred Peter, Influence of candidate susceptibility genes on tuberculosis in a high endemic region, 10.1016/j.molimm.2006.11.002
  202. Soilleux E. J., Barten R., Trowsdale J., Cutting Edge: DC-SIGN; a Related Gene, DC-SIGNR; and CD23 Form a Cluster on 19p13, 10.4049/jimmunol.165.6.2937
  203. Sonawane Avinash, Santos José Carlos, Mishra Bibhuti B., Jena Prajna, Progida Cinzia, Sorensen Ole E., Gallo Richard, Appelberg Rui, Griffiths Gareth, Cathelicidin is involved in the intracellular killing of mycobacteria in macrophages : The role of cathelicidin in mycobacteria killing, 10.1111/j.1462-5822.2011.01644.x
  204. Sreih Antoine, Ezzeddine Rana, Leng Lin, LaChance Avery, Yu Geraldine, Mizue Yuka, Subrahmanyan Lakshman, Pons-Estel Bernardo A., Abelson Anna-Karin, Gunnarsson Iva, Svenungsson Elisabet, Cavett Joshua, Glenn Stuart, Zhang Lin, Montgomery Ruth, Perl Andras, Salmon Jane, Alarcón-Riquelme Marta E., Harley John B., Bucala Richard, Dual effect of the macrophage migration inhibitory factor gene on the development and severity of human systemic lupus erythematosus, 10.1002/art.30624
  205. Srivastava , K. Kant , S. Verma , A. 2015 Role of environmental factors in transmission of tuberculosis
  206. Stagas Marios K., Papaetis Georgios S., Orphanidou Dora, Kostopoulos Charalambos, Syriou Stavroula, Reczko Martin, Drakoulis Nikolaos, Polymorphisms of the NRAMP1 gene: Distribution and susceptibility to the development of pulmonary tuberculosis in the Greek population, 10.12659/msm.881312
  207. Sutaria Nilay, Liu Ching-Ti, Chen Tai C., Vitamin D status, receptor gene polymorphisms, and supplementation on tuberculosis: A systematic review of case-control studies and randomized controlled trials, 10.1016/j.jcte.2014.08.001
  208. Szalai Csaba, Duba Jenö, Prohászka Zoltán, Kalina Ákos, Szabó Teréz, Nagy Bálint, Horváth Laura, Császár Albert, Involvement of polymorphisms in the chemokine system in the susceptibility for coronary artery disease (CAD). Coincidence of elevated Lp(a) and MCP-1 −2518 G/G genotype in CAD patients, 10.1016/s0021-9150(01)00423-3
  209. Tailleux Ludovic, Schwartz Olivier, Herrmann Jean-Louis, Pivert Elisabeth, Jackson Mary, Amara Ali, Legres Luc, Dreher Donatus, Nicod Laurent P., Gluckman Jean Claude, Lagrange Philippe H., Gicquel Brigitte, Neyrolles Olivier, DC-SIGN Is the MajorMycobacterium tuberculosisReceptor on Human Dendritic Cells, 10.1084/jem.20021468
  210. Takeda Kiyoshi, Akira Shizuo, Roles of Toll-like receptors in innate immune responses, 10.1046/j.1365-2443.2001.00458.x
  211. Takeda Kiyoshi, Kaisho Tsuneyasu, Akira Shizuo, TOLL-LIKERECEPTORS, 10.1146/annurev.immunol.21.120601.141126
  212. Theodoropoulos George E., Saridakis Vasilios, Karantanos Theodoros, Michalopoulos Nikolaos V., Zagouri Flora, Kontogianni Panagiota, Lymperi Maria, Gazouli Maria, Zografos George C., Toll-like receptors gene polymorphisms may confer increased susceptibility to breast cancer development, 10.1016/j.breast.2012.04.001
  213. Thuong N T T, Hawn T R, Thwaites G E, Chau T T H, Lan N T N, Quy H T, Hieu N T, Aderem A, Hien T T, Farrar J J, Dunstan S J, A polymorphism in human TLR2 is associated with increased susceptibility to tuberculous meningitis, 10.1038/sj.gene.6364405
  214. Thye T., Nejentsev S., Intemann C. D., Browne E. N., Chinbuah M. A., Gyapong J., Osei I., Owusu-Dabo E., Zeitels L. R., Herb F., Horstmann R. D., Meyer C. G., MCP-1 promoter variant -362C associated with protection from pulmonary tuberculosis in Ghana, West Africa, 10.1093/hmg/ddn352
  215. Thye Thorsten, , Vannberg Fredrik O, Wong Sunny H, Owusu-Dabo Ellis, Osei Ivy, Gyapong John, Sirugo Giorgio, Sisay-Joof Fatou, Enimil Anthony, Chinbuah Margaret A, Floyd Sian, Warndorff David K, Sichali Lifted, Malema Simon, Crampin Amelia C, Ngwira Bagrey, Teo Yik Y, Small Kerrin, Rockett Kirk, Kwiatkowski Dominic, Fine Paul E, Hill Philip C, Newport Melanie, Lienhardt Christian, Adegbola Richard A, Corrah Tumani, Ziegler Andreas, Morris Andrew P, Meyer Christian G, Horstmann Rolf D, Hill Adrian V S, , Genome-wide association analyses identifies a susceptibility locus for tuberculosis on chromosome 18q11.2, 10.1038/ng.639
  216. Tian G., Li X., Li H., Wang X., Cheng B., Systematic meta-analysis of the association between monocyte chemoattractant protein-1 -2518A/G polymorphism and risk of tuberculosis, 10.4238/2015.may.25.1
  217. Tong Xiang, Chen Lingmin, Liu Sitong, Yan Zhipeng, Peng Shifeng, Zhang Yonggang, Fan Hong, Polymorphisms in HLA-DRB1 Gene and the Risk of Tuberculosis: A Meta-analysis of 31 Studies, 10.1007/s00408-015-9692-z
  218. Tong Xiang, Yan Zhipeng, Zhou Qilong, Liu Sitong, Han Jing, Ma Yao, Yang Xue, Fan Hong, Association between the MIF-173G/C Polymorphism and Serum MIF levels with Pulmonary Tuberculosis: A Meta-analysis, 10.1038/s41598-017-00299-1
  219. Trinchieri Giorgio, Pflanz Stefan, Kastelein Robert A, The IL-12 Family of Heterodimeric Cytokines, 10.1016/s1074-7613(03)00296-6
  220. Tso Hoi W., Lau Yu Lung, Tam Cheuk M., Wong Hing S., Chiang Alan K. S., Associations betweenIL12BPolymorphisms and Tuberculosis in the Hong Kong Chinese Population, 10.1086/422693
  221. Taruna Madan, Singh Hari, Gupta VijayK, Murthy KJR, Sarma PuranamU, Vaid Mudit, Kaur Savneet, Association of SP-D, MBL and I-NOS genetic variants with pulmonary tuberculosis, 10.4103/0971-6866.29851
  222. Vallinoto Antonio C.R., Graça Ednelza S., Araújo Mauro S., Azevedo Vânia N., Cayres-Vallinoto Izaura, Machado Luiz Fernando A., Ishak Marluisa O.G., Ishak Ricardo, IFNG +874T/A polymorphism and cytokine plasma levels are associated with susceptibility to Mycobacterium tuberculosis infection and clinical manifestation of tuberculosis, 10.1016/j.humimm.2010.03.008
  223. Van Coillie Els, Van Damme Jo, Opdenakker Ghislain, The MCP/eotaxin subfamily of CC chemokines, 10.1016/s1359-6101(99)00005-2
  224. Vang Torkel, Congia Mauro, Macis Maria Doloretta, Musumeci Lucia, Orrú Valeria, Zavattari Patrizia, Nika Konstantina, Tautz Lutz, Taskén Kjetil, Cucca Francesco, Mustelin Tomas, Bottini Nunzio, Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant, 10.1038/ng1673
  225. Vang Torkel, Landskron Johannes, Viken Marte K., Oberprieler Nikolaus, Torgersen Knut M., Mustelin Tomas, Tasken Kjetil, Tautz Lutz, Rickert Robert C., Lie Benedicte A., The autoimmune-predisposing variant of lymphoid tyrosine phosphatase favors T helper 1 responses, 10.1016/j.humimm.2012.12.017
  226. Vannberg Fredrik O., Chapman Stephen J., Hill Adrian V. S., Human genetic susceptibility to intracellular pathogens : Susceptibility to intracellular pathogens, 10.1111/j.1600-065x.2010.00996.x
  227. Vannberg Fredrik O., Chapman Stephen J., Khor Chiea C., Tosh Kerrie, Floyd Sian, Jackson-Sillah Dolly, Crampin Amelia, Sichali Lifted, Bah Boubacar, Gustafson Per, Aaby Peter, McAdam Keith P. W. J., Bah-Sow Oumou, Lienhardt Christian, Sirugo Giorgio, Fine Paul, Hill Adrian V. S., CD209 Genetic Polymorphism and Tuberculosis Disease, 10.1371/journal.pone.0001388
  228. Vásquez-Loarte Tania, Trubnykova Milana, Guio Heinner, Genetic association meta-analysis: a new classification to assess ethnicity using the association of MCP-1 -2518 polymorphism and tuberculosis susceptibility as a model, 10.1186/s12863-015-0280-2
  229. Veillette André, Latour Sylvain, Davidson Dominique, NEGATIVE REGULATION OF IMMUNORECEPTOR SIGNALING, 10.1146/annurev.immunol.20.081501.130710
  230. VEJBAESYA Sasijit, CHIERAKUL Nitipatana, LUANGTRAKOOL Panpimon, SERMDUANGPRATEEP Chutima, NRAMP1 and TNF-? polymorphisms and susceptibility to tuberculosis in Thais, 10.1111/j.1440-1843.2006.01037.x
  231. Velez Edwards Digna R., Tacconelli Alessandra, Wejse Christian, Hill Philip C., Morris Gerard A. J., Edwards Todd L., Gilbert John R., Myers Jamie L., Park Yo Son, Stryjewski Martin E., Abbate Eduardo, Estevan Rosa, Rabna Paulo, Novelli Giuseppe, Hamilton Carol D., Adegbola Richard, Østergaard Lars, Williams Scott M., Scott William K., Sirugo Giorgio, MCP1 SNPs and Pulmonary Tuberculosis in Cohorts from West Africa, the USA and Argentina: Lack of Association or Epistasis with IL12B Polymorphisms, 10.1371/journal.pone.0032275
  232. Verreck Frank A. W., de Boer Tjitske, Hoeve Marieke, van Dissel Jaap T., Sanal Ozden, Kurimoto Masashi, Ottenhoff Tom H. M., Human Host Defense and Cytokines in Mycobacterial Infectious Diseases: Interleukin‐18 Cannot Compensate for Genetic Defects in the Interleukin‐12 System, 10.1086/341314
  233. Walsh Kevin P., Mills Kingston H.G., Dendritic cells and other innate determinants of T helper cell polarisation, 10.1016/j.it.2013.07.006
  234. Wang J, Freeman D J, Grundy S M, Levine D M, Guerra R, Cohen J C, Linkage between cholesterol 7alpha-hydroxylase and high plasma low-density lipoprotein cholesterol concentrations., 10.1172/jci1343
  235. WANG DONG, LUO LIANG, CHEN WEI, CHEN LIAN-ZHOU, ZENG WEN-TAO, LI WEN, HUANG XIAO-HUI, Significance of the vascular endothelial growth factor and the macrophage migration inhibitory factor in the progression of hepatocellular carcinoma, 10.3892/or.2013.2946
  236. Wang Jia-Jia, Xia Xian, Tang Shai-Di, Wang Jie, Deng Xiao-Zhao, Zhang Yun, Yue Ming, Meta-Analysis on the Associations of TLR2 Gene Polymorphisms with Pulmonary Tuberculosis Susceptibility among Asian Populations, 10.1371/journal.pone.0075090
  237. Wang, Journal of Biological Regulators and Homeostatic Agents, 30, 239 (2016)
  238. Wang Decheng, Zhou Wenjiang, Lu Shuihua, Wang Qingnan, Feng Yanling, Zhu Guofeng, Li Liang, Song Yanzheng, Gao Qian, Increased density of macrophage migration inhibitory factor (MIF) in tuberculosis granuloma, 10.1016/j.yexmp.2012.05.004
  239. Wejse, The American Journal of Clinical Nutrition, 86, 1376 (2007)
  240. WHO 2014 WHO|Global tuberculosis report 2014 http://www.who.int/tb/publications/global_report/en/
  241. WHO 2015 WHO|Global tuberculosis report 2015 http://www.who.int/tb/publications/global_report/en/
  242. Wilkinson Robert J, Llewelyn Martin, Toossi Zahra, Patel Punita, Pasvol Geoffrey, Lalvani Ajit, Wright Dennis, Latif Mohammed, Davidson Robert N, Influence of vitamin D deficiency and vitamin D receptor polymorphisms on tuberculosis among Gujarati Asians in west London: a case-control study, 10.1016/s0140-6736(99)02301-6
  243. Wu Linlin, Hu Yi, Li Dange, Jiang Weili, Xu Biao, Screening toll-like receptor markers to predict latent tuberculosis infection and subsequent tuberculosis disease in a Chinese population, 10.1186/s12881-015-0166-1
  244. Wu Sou-Pan, Leng Lin, Feng Zeny, Liu Nianjun, Zhao Hongyu, McDonald Courtney, Lee Annette, Arnett Frank C., Gregersen Peter K., Mayes Maureen D., Bucala Richard, Macrophage migration inhibitory factor promoter polymorphisms and the clinical expression of scleroderma, 10.1002/art.22179
  245. Wu Dennis J., Zhou Wenbo, Enouz Sarah, Orrú Valeria, Stanford Stephanie M., Maine Christian J., Rapini Novella, Sawatzke Kristy, Engel Isaac, Fiorillo Edoardo, Sherman Linda A., Kronenberg Mitch, Zehn Dietmar, Peterson Erik, Bottini Nunzio, Autoimmunity-Associated LYP-W620 Does Not Impair Thymic Negative Selection of Autoreactive T Cells, 10.1371/journal.pone.0086677
  246. Xue Y., Zhao Z. Q., Wang H. J., Jin L., Liu C. P., Wang Y., Li J. C., Toll-like receptors 2 and 4 gene polymorphisms in a southeastern Chinese population with tuberculosis, 10.1111/j.1744-313x.2009.00892.x
  247. Yamada Gen, Shijubo Noriharu, Takagi-Takahashi Yoko, Nishihira Jun, Mizue Yuka, Kikuchi Kokichi, Abe Shosaku, Elevated Levels of Serum Macrophage Migration Inhibitory Factor in Patients with Pulmonary Tuberculosis, 10.1006/clim.2002.5255
  248. Yamamoto M., Role of Adaptor TRIF in the MyD88-Independent Toll-Like Receptor Signaling Pathway, 10.1126/science.1087262
  249. Yao Song, Ambrosone Christine B., Associations between vitamin D deficiency and risk of aggressive breast cancer in African-American women, 10.1016/j.jsbmb.2012.09.010
  250. Yende Sachin, Angus Derek C., Kong Lan, Kellum John A., Weissfeld Lisa, Ferrell Robert, Finegold David, Carter Melinda, Leng Lin, Peng Zhi-Yong, Bucala Richard, The influence of macrophage migration inhibitory factor gene polymorphisms on outcome from community-acquired pneumonia, 10.1096/fj.09-129445
  251. Yi, International Journal of Clinical and Experimental Pathology, 8, 12437 (2015)
  252. Yim J-J, Lee H W, Lee H S, Kim Y W, Han S K, Shim Y-S, Holland S M, The association between microsatellite polymorphisms in intron II of the human Toll-like receptor 2 gene and tuberculosis among Koreans, 10.1038/sj.gene.6364274
  253. Yuliwulandari Rika, Sachrowardi Qomariyah, Nakajima Humiaki, Kashiwase Koichi, Hirayasu Kouyuki, Mabuchi Akihiko, Sofro Abdul Salam Mudzakir, Tokunaga Katsushi, Association of HLA-A, -B, and -DRB1 with pulmonary tuberculosis in western Javanese Indonesia, 10.1016/j.humimm.2010.04.005
  254. Zhang Jinyi, Zahir Naima, Jiang Qiuhong, Miliotis Helen, Heyraud Stephanie, Meng Xianwang, Dong Baoxia, Xie Gang, Qiu Frank, Hao Zhenyue, McCulloch Christopher A, Keystone Edward C, Peterson Alan C, Siminovitch Katherine A, The autoimmune disease–associated PTPN22 variant promotes calpain-mediated Lyp/Pep degradation associated with lymphocyte and dendritic cell hyperresponsiveness, 10.1038/ng.904
  255. Zhang Yonggang, Zhang Jie, Zeng Lingjun, Huang Honglang, Yang Min, Fu Xiaowei, Tian Can, Xiang Zhangpeng, Huang Jin, Fan Hong, The -2518A/G Polymorphism in the MCP-1 Gene and Tuberculosis Risk: A Meta-Analysis, 10.1371/journal.pone.0038918
  256. Zheng Ruijuan, Zhou Yan, Qin Lianhua, Jin Ruiliang, Wang Jie, Lu Junmei, Wang WeiBing, Tang Shenjie, Hu Zhongyi, Relationship between polymorphism of DC-SIGN (CD209) gene and the susceptibility to pulmonary tuberculosis in an eastern Chinese population, 10.1016/j.humimm.2010.11.004
Bibliographic reference Qrafli, Mounia ; Najimi, Mustapha ; Elaouad, Rajae ; Sadki, Khalid. Current immunogenetic predisposition to tuberculosis in the Moroccan population.. In: International Journal of Immunogenetics, Vol. 44, no.6, p. 286-304 (2017)
Permanent URL http://hdl.handle.net/2078.1/201385