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Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.

Bibliographic reference Baselet, Bjorn ; Azimzadeh, Omid ; Erbeldinger, Nadine ; Bakshi, Mayur V ; Dettmering, Till ; et. al. Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses.. In: Frontiers in Pharmacology, Vol. 8, p. 570 (2017)
Permanent URL http://hdl.handle.net/2078.1/190062
  1. Aird W. C., Phenotypic Heterogeneity of the Endothelium: I. Structure, Function, and Mechanisms, 10.1161/01.res.0000255691.76142.4a
  2. Aird W. C., Phenotypic Heterogeneity of the Endothelium: II. Representative Vascular Beds, 10.1161/01.res.0000255690.03436.ae
  3. Akamatsu Hiroko, Karasawa Kumiko, Omatsu Tokuhiko, Isobe Yoshiharu, Ogata Risa, Koba Yusuke, First experience of carbon-ion radiotherapy for early breast cancer, 10.1007/s11604-014-0300-6
  4. Aleman Berthe M.P., Moser Elizabeth C., Nuver Janine, Suter Thomas M., Maraldo Maja V., Specht Lena, Vrieling Conny, Darby Sarah C., Cardiovascular disease after cancer therapy, 10.1016/j.ejcsup.2014.03.002
  5. Asaithamby Aroumougame, Chen David J., Mechanism of cluster DNA damage repair in response to high-atomic number and energy particles radiation, 10.1016/j.mrfmmm.2010.11.002
  6. Azimzadeh Omid, Sievert Wolfgang, Sarioglu Hakan, Merl-Pham Juliane, Yentrapalli Ramesh, Bakshi Mayur V., Janik Dirk, Ueffing Marius, Atkinson Michael J., Multhoff Gabriele, Tapio Soile, Integrative Proteomics and Targeted Transcriptomics Analyses in Cardiac Endothelial Cells Unravel Mechanisms of Long-Term Radiation-Induced Vascular Dysfunction, 10.1021/pr501141b
  7. Azimzadeh Omid, Sievert Wolfgang, Sarioglu Hakan, Yentrapalli Ramesh, Barjaktarovic Zarko, Sriharshan Arundhathi, Ueffing Marius, Janik Dirk, Aichler Michaela, Atkinson Michael J., Multhoff Gabriele, Tapio Soile, PPAR Alpha: A Novel Radiation Target in Locally ExposedMus musculusHeart Revealed by Quantitative Proteomics, 10.1021/pr400071g
  8. Barnett Gillian C., West Catherine M. L., Dunning Alison M., Elliott Rebecca M., Coles Charlotte E., Pharoah Paul D. P., Burnet Neil G., Normal tissue reactions to radiotherapy: towards tailoring treatment dose by genotype, 10.1038/nrc2587
  9. Baselet Bjorn, Belmans Niels, Coninx Emma, Lowe Donna, Janssen Ann, Michaux Arlette, Tabury Kevin, Raj Kenneth, Quintens Roel, Benotmane Mohammed A., Baatout Sarah, Sonveaux Pierre, Aerts An, Functional Gene Analysis Reveals Cell Cycle Changes and Inflammation in Endothelial Cells Irradiated with a Single X-ray Dose, 10.3389/fphar.2017.00213
  10. BECK MICHAËL, ROMBOUTS CHARLOTTE, MOREELS MARJAN, AERTS AN, QUINTENS ROEL, TABURY KEVIN, MICHAUX ARLETTE, JANSSEN ANN, NEEFS MIEKE, ERNST ERIC, DIERIKS BIRGER, LEE RYONFA, DE VOS WINNOK H., LAMBERT CHARLES, VAN OOSTVELDT PATRICK, BAATOUT SARAH, Modulation of gene expression in endothelial cells in response to high LET nickel ion irradiation, 10.3892/ijmm.2014.1893
  11. Benjamini, J. R. Stat. Soc. Ser. B Methodol., 57, 289 (1995)
  12. Bentzen Søren M., Preventing or reducing late side effects of radiation therapy: radiobiology meets molecular pathology, 10.1038/nrc1950
  13. Boisvert W A, Santiago R, Curtiss L K, Terkeltaub R A, A leukocyte homologue of the IL-8 receptor CXCR-2 mediates the accumulation of macrophages in atherosclerotic lesions of LDL receptor-deficient mice., 10.1172/jci1195
  14. Borghini Andrea, Luca Gianicolo Emilio Antonio, Picano Eugenio, Andreassi Maria Grazia, Ionizing radiation and atherosclerosis: Current knowledge and future challenges, 10.1016/j.atherosclerosis.2013.06.010
  15. Chang Joe Y., Jabbour Salma K., De Ruysscher Dirk, Schild Steven E., Simone Charles B., Rengan Ramesh, Feigenberg Steven, Khan Atif J., Choi Noah C., Bradley Jeffrey D., Zhu Xiaorong R., Lomax Antony J., Hoppe Bradford S., Consensus Statement on Proton Therapy in Early-Stage and Locally Advanced Non–Small Cell Lung Cancer, 10.1016/j.ijrobp.2016.01.036
  16. Corre Isabelle, Guillonneau Maëva, Paris François, Membrane Signaling Induced by High Doses of Ionizing Radiation in the Endothelial Compartment. Relevance in Radiation Toxicity, 10.3390/ijms141122678
  17. Darby Sarah C., Ewertz Marianne, McGale Paul, Bennet Anna M., Blom-Goldman Ulla, Brønnum Dorthe, Correa Candace, Cutter David, Gagliardi Giovanna, Gigante Bruna, Jensen Maj-Britt, Nisbet Andrew, Peto Richard, Rahimi Kazem, Taylor Carolyn, Hall Per, Risk of Ischemic Heart Disease in Women after Radiotherapy for Breast Cancer, 10.1056/nejmoa1209825
  18. Deanfield, Circulation, 115, 1285 (2007)
  19. DUVE Christian, Lysosomes revisited, 10.1111/j.1432-1033.1983.tb07841.x
  20. Durante Marco, Loeffler Jay S., Charged particles in radiation oncology, 10.1038/nrclinonc.2009.183
  21. Ebrahimian T., Le Gallic C., Stefani J., Dublineau I., Yentrapalli R., Harms-Ringdahl M., Haghdoost S., Chronic Gamma-Irradiation Induces a Dose-Rate-Dependent Pro-inflammatory Response and Associated Loss of Function in Human Umbilical Vein Endothelial Cells, 10.1667/rr13732.1
  22. Eden Eran, Lipson Doron, Yogev Sivan, Yakhini Zohar, Discovering Motifs in Ranked Lists of DNA Sequences, 10.1371/journal.pcbi.0030039
  23. Eden Eran, Navon Roy, Steinfeld Israel, Lipson Doron, Yakhini Zohar, GOrilla: a tool for discovery and visualization of enriched GO terms in ranked gene lists, 10.1186/1471-2105-10-48
  24. Fernandez-Gonzalo Rodrigo, Baatout Sarah, Moreels Marjan, Impact of Particle Irradiation on the Immune System: From the Clinic to Mars, 10.3389/fimmu.2017.00177
  25. Fernández-Hernando Carlos, Yu Jun, Dávalos Alberto, Prendergast Jay, Sessa William C., Endothelial-Specific Overexpression of Caveolin-1 Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice, 10.2353/ajpath.2010.091287
  26. Sherwood Louis M., Parris Edith E., Folkman Judah, Tumor Angiogenesis: Therapeutic Implications, 10.1056/nejm197111182852108
  27. Fournier C., Taucher-Scholz G., Radiation induced cell cycle arrest: an overview of specific effects following high-LET exposure, 10.1016/s0167-8140(04)80031-8
  28. Frank Philippe G., Endothelial Caveolae and Caveolin-1 as Key Regulators of Atherosclerosis, 10.2353/ajpath.2010.100247
  29. Galbiati F., Targeted downregulation of caveolin-1 is sufficient to drive cell transformation and hyperactivate the p42/44 MAP kinase cascade, 10.1093/emboj/17.22.6633
  30. Grabham Peter, Hu Burong, Sharma Preety, Geard Charles, Effects of Ionizing Radiation on Three-Dimensional Human Vessel Models: Differential Effects According to Radiation Quality and Cellular Development, 10.1667/rr2289.1
  31. Grabham Peter, Sharma Preety, Bigelow Alan, Geard Charles, Two distinct types of the inhibition of vasculogenesis by different species of charged particles, 10.1186/2045-824x-5-16
  32. HADA Megumi, GEORGAKILAS Alexandros G., Formation of Clustered DNA Damage after High-LET Irradiation: A Review, 10.1269/jrr.07123
  33. Harrington Jennifer R., The Role of MCP-1 in Atherosclerosis, 10.1634/stemcells.18-1-65
  34. Hauck Stefanie M., Dietter Johannes, Kramer Roxane L., Hofmaier Florian, Zipplies Johanna K., Amann Barbara, Feuchtinger Annette, Deeg Cornelia A., Ueffing Marius, Deciphering Membrane-Associated Molecular Processes in Target Tissue of Autoimmune Uveitis by Label-Free Quantitative Mass Spectrometry, 10.1074/mcp.m110.001073
  35. Hayashi T., Kusunoki Y., Hakoda M., Morishita Y., Kubo Y., Maki M., Kasagi F., Kodama K., Macphee D. G., Kyoizumi S., Radiation dose-dependent increases in inflammatory response markers in A-bomb survivors, 10.1080/0955300021000038662
  36. Helm Alexander, Lee Ryonfa, Durante Marco, Ritter Sylvia, The Influence of C-Ions and X-rays on Human Umbilical Vein Endothelial Cells, 10.3389/fonc.2016.00005
  37. Hulit James, Bash Tal, Fu Maofu, Galbiati Ferruccio, Albanese Chris, Sage Daniel R., Schlegel Amnon, Zhurinsky Jacob, Shtutman Michael, Ben-Ze'ev Avri, Lisanti Michael P., Pestell Richard G., The Cyclin D1 Gene Is Transcriptionally Repressed by Caveolin-1, 10.1074/jbc.m000321200
  38. , Preface, Executive Summary and Glossary, 10.1016/j.icrp.2007.10.003
  39. Ikuta, Immunology, 73, 71 (1991)
  40. Jermann Martin, Particle Therapy Statistics in 2014, 10.14338/ijpt-15-00013
  41. Khaled, Low and high LET Irradiation of Human Aortic Endothelial Cells Induces Dose and Time Dependent Adhesion of Monocytes Which Is Mediated by Chemokines Expressed by the Irradiated Endothelium (2011)
  42. Khaled Saman, Gupta Kiran B., Kucik Dennis F., Ionizing Radiation Increases Adhesiveness of Human Aortic Endothelial Cells via a Chemokine-Dependent Mechanism, 10.1667/rr2557.1
  43. KIYOHARA Hiroki, ISHIZAKI Yasuki, SUZUKI Yoshiyuki, KATOH Hiroyuki, HAMADA Nobuyuki, OHNO Tatsuya, TAKAHASHI Takeo, KOBAYASHI Yasuhiko, NAKANO Takashi, Radiation-induced ICAM-1 Expression via TGF-β1 Pathway on Human Umbilical Vein Endothelial Cells; Comparison between X-ray and Carbon-ion Beam Irradiation, 10.1269/jrr.10061
  44. Klein D, Schmitz T, Verhelst V, Panic A, Schenck M, Reis H, Drab M, Sak A, Herskind C, Maier P, Jendrossek V, Endothelial Caveolin-1 regulates the radiation response of epithelial prostate tumors, 10.1038/oncsis.2015.9
  45. Krämer M., Weyrather W. K., Scholz M., The Increased Biological Effectiveness of Heavy Charged Particles: From Radiobiology to Treatment Planning, 10.1177/153303460300200507
  46. Kucik, FASEB J., 24, (1028).1011 (2010)
  47. Kumar, Robbins Basic Pathology (2013)
  48. LAEMMLI U. K., Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, 10.1038/227680a0
  49. Lee Ryonfa, Nasonova Elena, Hartel Carola, Durante Marco, Ritter Sylvia, Chromosome aberration measurements in mitotic and G2-PCC lymphocytes at the standard sampling time of 48 h underestimate the effectiveness of high-LET particles, 10.1007/s00411-011-0360-2
  50. Libby Peter, Inflammation in atherosclerosis, 10.1038/nature01323
  51. Liu Jun, Razani Babak, Tang Shaoqing, Terman Bruce I., Ware J. Anthony, Lisanti Michael P., Angiogenesis Activators and Inhibitors Differentially Regulate Caveolin-1 Expression and Caveolae Formation in Vascular Endothelial Cells : ANGIOGENESIS INHIBITORS BLOCK VASCULAR ENDOTHELIAL GROWTH FACTOR-INDUCED DOWN-REGULATION OF CAVEOLIN-1, 10.1074/jbc.274.22.15781
  52. Liu S, Effects of Hydrogen Peroxide and Phorbol Myristate Acetate on Endothelial Transport and F-Actin Distribution, 10.1006/excr.1995.1056
  53. Lowe Donna J., Raj Kenneth, Quantitation of Endothelial Cell Adhesiveness In Vitro, 10.3791/52924
  54. Lowe Donna, Raj Kenneth, Premature aging induced by radiation exhibits pro-atherosclerotic effects mediated by epigenetic activation of CD44 expression, 10.1111/acel.12253
  55. Mackay F., Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55, 10.1084/jem.177.5.1277
  56. Mao Xiao Wen, Favre Cecile J., Fike John R., Kubinova Lucie, Anderson Ella, Campbell-Beachler Mary, Jones Tamako, Smith Anna, Rightnar Steven, Nelson Gregory A., High-LET Radiation-Induced Response of Microvessels in the Hippocampus, 10.1667/rr1728.1
  57. Meeren A. Van Der, Bertho J.-M., Vandamme M., Gaugler M.-H., Ionizing radiation enhances IL-6 and IL-8 production by human endothelial cells, 10.1080/09629359791677
  58. Merl Juliane, Ueffing Marius, Hauck Stefanie M., von Toerne Christine, Direct comparison of MS-based label-free and SILAC quantitative proteome profiling strategies in primary retinal Müller cells, 10.1002/pmic.201100549
  59. Morais Christudas, Ebrahem Quteba, Anand-Apte Bela, Parat Marie-Odile, Altered Angiogenesis in Caveolin-1 Gene–Deficient Mice Is Restored by Ablation of Endothelial Nitric Oxide Synthase, 10.1016/j.ajpath.2011.12.018
  60. Moreels Marjan, de Saint-Georges Louis, Vanhavere Filip, Baatout Sarah, Stress and Radiation Responsiveness, Stress Challenges and Immunity in Space (2012) ISBN:9783642222719 p.239-260, 10.1007/978-3-642-22272-6_17
  61. Münzel Thomas, Sinning Christoph, Post Felix, Warnholtz Ascan, Schulz Eberhard, Pathophysiology, diagnosis and prognostic implications of endothelial dysfunction, 10.1080/07853890701854702
  62. Newhauser Wayne D., Durante Marco, Assessing the risk of second malignancies after modern radiotherapy, 10.1038/nrc3069
  63. Nichols Romaine C, Proton therapy for pancreatic cancer, 10.4251/wjgo.v7.i9.141
  64. Pavlides Stephanos, Gutierrez-Pajares Jorge L., Iturrieta Jeannette, Lisanti Michael P., Frank Philippe G., Endothelial caveolin-1 plays a major role in the development of atherosclerosis, 10.1007/s00441-013-1767-7
  65. Rombouts Charlotte, Aerts An, Beck Michael, De Vos Winnok H., Van Oostveldt Patrick, Benotmane Mohammed Abderrafi, Baatout Sarah, Differential response to acute low dose radiation in primary and immortalized endothelial cells, 10.3109/09553002.2013.806831
  66. Rombouts Charlotte, Aerts An, Quintens Roel, Baselet Bjorn, El-Saghire Hussein, Harms-Ringdahl Mats, Haghdoost Siamak, Janssen Ann, Michaux Arlette, Yentrapalli Ramesh, Benotmane Mohammed Abderrafi, Van Oostveldt Patrick, Baatout Sarah, Transcriptomic profiling suggests a role for IGFBP5 in premature senescence of endothelial cells after chronic low dose rate irradiation, 10.3109/09553002.2014.905724
  67. Sbaa Elhem, Frérart Françoise, Feron Olivier, The Double Regulation of Endothelial Nitric Oxide Synthase by Caveolae and Caveolin: A Paradox Solved Through the Study of Angiogenesis, 10.1016/j.tcm.2005.05.006
  68. Scholz M., Effects of Ion Radiation on Cells and Tissues, Radiation Effects on Polymers for Biological Use (2003) ISBN:9783540440208 p.95-155, 10.1007/3-540-45668-6_4
  69. Schuett Harald, Luchtefeld Maren, Grothusen Christina, Grote Karsten, Schieffer Bernhard, How much is too much? Interleukin-6 and its signalling in atherosclerosis, 10.1160/th09-05-0297
  70. Schultz-Hector Susanne, Trott Klaus-Rüdiger, Radiation-induced cardiovascular diseases: Is the epidemiologic evidence compatible with the radiobiologic data?, 10.1016/j.ijrobp.2006.08.071
  71. Schulz-Ertner Daniela, Tsujii Hirohiko, Particle Radiation Therapy Using Proton and Heavier Ion Beams, 10.1200/jco.2006.09.7816
  72. Sofia Vala Inês, Martins Leila R., Imaizumi Natsuko, Nunes Raquel J., Rino José, Kuonen François, Carvalho Lara M., Rüegg Curzio, Grillo Isabel Monteiro, Barata João Taborda, Mareel Marc, Santos Susana Constantino Rosa, Low Doses of Ionizing Radiation Promote Tumor Growth and Metastasis by Enhancing Angiogenesis, 10.1371/journal.pone.0011222
  73. Sonveaux, Cancer Res., 63, 1012 (2003)
  74. Soucy Kevin G., Lim Hyun Kyo, Kim Jae Hyung, Oh Young, Attarzadeh David O., Sevinc Baris, Kuo Maggie M., Shoukas Artin A., Vazquez Marcelo E., Berkowitz Dan E., HZE56Fe-Ion Irradiation Induces Endothelial Dysfunction in Rat Aorta: Role of Xanthine Oxidase, 10.1667/rr2598.1
  75. Stone Helen B, Coleman C Norman, Anscher Mitchell S, McBride William H, Effects of radiation on normal tissue: consequences and mechanisms, 10.1016/s1470-2045(03)01191-4
  76. Suetens Annelies, Konings Katrien, Moreels Marjan, Quintens Roel, Verslegers Mieke, Soors Els, Tabury Kevin, Grégoire Vincent, Baatout Sarah, Higher Initial DNA Damage and Persistent Cell Cycle Arrest after Carbon Ion Irradiation Compared to X-irradiation in Prostate and Colon Cancer Cells, 10.3389/fonc.2016.00087
  77. SUNDQVIST T., LIU S. M., Hydrogen peroxide stimulates endocytosis in cultured bovine aortic endothelial cells, 10.1111/j.1748-1716.1993.tb09604.x
  78. Supek Fran, Bošnjak Matko, Škunca Nives, Šmuc Tomislav, REVIGO Summarizes and Visualizes Long Lists of Gene Ontology Terms, 10.1371/journal.pone.0021800
  79. Takahashi, Cancer Res., 63, 4253 (2003)
  80. Vita J. A., Keaney J. F., Endothelial Function: A Barometer for Cardiovascular Risk?, 10.1161/01.cir.0000028581.07992.56
  81. Widlansky Michael E, Gokce Noyan, Keaney John F, Vita Joseph A, The clinical implications of endothelial dysfunction, 10.1016/s0735-1097(03)00994-x
  82. Jay Widmer R., Lerman Amir, Endothelial dysfunction and cardiovascular disease, 10.5339/gcsp.2014.43
  83. Wilson Robert R., Radiological Use of Fast Protons, 10.1148/47.5.487
  84. Wu Jiang, Liu Wei, Bemis Amanda, Wang Eunice, Qiu Yongchang, Morris Elisabeth A., Flannery Carl R., Yang Zhiyong, Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis, 10.1002/art.22876
  85. Yentrapalli Ramesh, Azimzadeh Omid, Barjaktarovic Zarko, Sarioglu Hakan, Wojcik Andrzej, Harms-Ringdahl Mats, Atkinson Michael J., Haghdoost Siamak, Tapio Soile, Quantitative proteomic analysis reveals induction of premature senescence in human umbilical vein endothelial cells exposed to chronic low-dose rate gamma radiation, 10.1002/pmic.201200463
  86. Yentrapalli Ramesh, Azimzadeh Omid, Sriharshan Arundhathi, Malinowsky Katharina, Merl Juliane, Wojcik Andrzej, Harms-Ringdahl Mats, Atkinson Michael J., Becker Karl-Friedrich, Haghdoost Siamak, Tapio Soile, The PI3K/Akt/mTOR Pathway Is Implicated in the Premature Senescence of Primary Human Endothelial Cells Exposed to Chronic Radiation, 10.1371/journal.pone.0070024
  87. Yu Tao, Parks Brian W., Yu Shaohua, Srivastava Roshni, Gupta Kiran, Wu Xing, Khaled Saman, Chang Polly Y., Kabarowski Janusz H., Kucik Dennis F., Iron-Ion Radiation Accelerates Atherosclerosis in Apolipoprotein E-Deficient Mice, 10.1667/rr2482.1
  88. Zhu Hua, Yue Jingyin, Pan Zui, Wu Hao, Cheng Yan, Lu Huimei, Ren Xingcong, Yao Ming, Shen Zhiyuan, Yang Jin-Ming, Involvement of Caveolin-1 in Repair of DNA Damage through Both Homologous Recombination and Non-Homologous End Joining, 10.1371/journal.pone.0012055