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One-year and longer dual antiplatelet therapy after an acute coronary syndrome: a Belgian position paper

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Sinnaeve, Peter R. Desmet, Walter Descamps, Olivier [UCL] Gevaert, Sofie De Backer, Guy Beauloye, Christophe [UCL]

(eng) Acute coronary syndrome patients receive DAPT up to one year after their initial event. Exceptions to the guideline-recommended one-year rule, however, are not uncommon. The reasoning behind shorter treatments, such as unacceptable bleeding risk or urgent surgery, should be well documented in the patient's charts and discharge letter. Based on recent evidence, patients at high risk for repetitive events should continue on low-dose ticagrelor without a significant interruption at one year and indefinitely in the absence of excess bleeding risk. As there is currently no reimbursement, policy makers and insurers should be made aware of the continuing risk and unmet clinical need in this patient population. Nevertheless, many unsolved questions need to be answered, both through additional analyses from recent trials such as PEGASUS-TIMI 54 or DAPT, as well as new carefully designed clinical studies.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 2017
Language Anglais
Journal information "Acta Cardiologica : an international journal of cardiology" - Vol. 72, no. 1, p. 19-27 (2017)
Peer reviewed yes
Publisher Taylor & Francis ((United Kingdom) London)
issn 0001-5385
e-issn 1784-973X
Publication status Publié
Affiliations UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire
UCL - (SLuc) Service de cardiologie
Keywords Dual antiplatelet therapy ; STEMI ; Myocardial infarction
Links
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Bibliographic reference Sinnaeve, Peter R. ; Desmet, Walter ; Descamps, Olivier ; Gevaert, Sofie ; De Backer, Guy ; et. al. One-year and longer dual antiplatelet therapy after an acute coronary syndrome: a Belgian position paper. In: Acta Cardiologica : an international journal of cardiology, Vol. 72, no. 1, p. 19-27 (2017)
Permanent URL http://hdl.handle.net/2078.1/186161