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EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial agents in animal husbandry in the European Union, and the resulting impacts on food safety (RONAFA)

Bibliographic reference EMA Committee for Medicinal Products for Veterinary Use (CVMP) ; EFSA Panel on Biological Hazards (BIOHAZ), ; Murphy, David ; Ricci, Antonia ; Auce, Zanda ; et. al. EMA and EFSA Joint Scientific Opinion on measures to reduce the need to use antimicrobial agents in animal husbandry in the European Union, and the resulting impacts on food safety (RONAFA). In: EFSA Journal, Vol. 15, no.1, p. 4666 [1-245] (2017)
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  1. Aanensen David M., Feil Edward J., Holden Matthew T. G., Dordel Janina, Yeats Corin A., Fedosejev Artemij, Goater Richard, Castillo-Ramírez Santiago, Corander Jukka, Colijn Caroline, Chlebowicz Monika A., Schouls Leo, Heck Max, Pluister Gerlinde, Ruimy Raymond, Kahlmeter Gunnar, Åhman Jenny, Matuschek Erika, Friedrich Alexander W., Parkhill Julian, Bentley Stephen D., Spratt Brian G., Grundmann Hajo, Whole-Genome Sequencing for Routine Pathogen Surveillance in Public Health: a Population Snapshot of InvasiveStaphylococcus aureusin Europe, 10.1128/mbio.00444-16
  2. Aarestrup Frank Møller, Association between the consumption of antimicrobial agents in animal husbandry and the occurrence of resistant bacteria among food animals, 10.1016/s0924-8579(99)90059-6
  3. AARESTRUP FRANK MØLLER, Occurrence, selection and spread of resistance to antimicrobial agents used for growth promotion for food animals in Denmark: Chapter 1: Introduction, 10.1111/j.1600-0463.2000.tb05380.x
  4. Aarestrup Frank M., Oliver Duran C., Burch David G. S., Antimicrobial resistance in swine production, 10.1017/s1466252308001503
  5. Aarestrup Frank M., Jensen Vibeke F., Emborg Hanne-Dorthe, Jacobsen Erik, Wegener Henrik C., Changes in the use of antimicrobials and the effects on productivity of swine farms in Denmark, 10.2460/ajvr.71.7.726
  6. Aarnink A. J. A., Schrama J. W., Heetkamp M. J. W., Stefanowska J., Huynh T. T. T., Temperature and body weight affect fouling of pig pens, 10.2527/jas.2005-521
  7. Aaarestrup, Antimicrobial Resistance in Bacteria of Animal Origin, 37 (2006)
  8. Abudabos A.M., Al-Batshan H.A., Murshed M.A., Effects of prebiotics and probiotics on the performance and bacterial colonization of broiler chickens, 10.4314/sajas.v45i4.8
  9. Abu-Elala Nermeen M., Mohamed Samah H., Zaki Manal M., Eissa Alaa Eldin, Assessment of the immune-modulatory and antimicrobial effects of dietary chitosan on Nile tilapia (Oreochrmis niloticus) with special emphasis to its bio-remediating impacts, 10.1016/j.fsi.2015.08.004
  10. Abu-Shanab Ahmed, Quigley Eamonn MM, Diagnosis of small intestinal bacterial overgrowth: the challenges persist!, 10.1586/17474124.3.1.77
  11. ACAR J., RÖSTEL B., Antimicrobial resistance: an overview : -EN- -FR- -ES-, 10.20506/rst.20.3.1309
  12. Ackermann Mathias, Engels Monika, Pro and contra IBR-eradication, 10.1016/j.vetmic.2005.11.043
  13. Adorian Taida Juliana, Goulart Fernanda Rodrigues, Mombach Patrícia Inês, de Menezes Lovatto Naglezi, Dalcin Marina, Molinari Mabel, Lazzari Rafael, da Silva Leila Picolli, Effect of different dietary fiber concentrates on the metabolism and indirect immune response in silver catfish, 10.1016/j.anifeedsci.2016.03.001
  14. Agarwal S.K., Marshall G.D., Stress effects on immunity and its application to clinical immunology, 10.1111/j.1365-2222.2001.01005.x
  15. Agersø Yvonne, Aarestrup Frank M., Voluntary ban on cephalosporin use in Danish pig production has effectively reduced extended-spectrum cephalosporinase-producing Escherichia coli in slaughter pigs, 10.1093/jac/dks427
  16. Alban L., Dahl J., Andreasen M., Petersen J.V., Sandberg M., Possible impact of the “yellow card” antimicrobial scheme on meat inspection lesions in Danish finisher pigs, 10.1016/j.prevetmed.2012.11.010
  17. Alban Lis, Petersen Jesper, Busch Marie, A comparison between lesions found during meat inspection of finishing pigs raised under organic/free-range conditions and conventional, indoor conditions, 10.1186/2055-5660-1-4
  18. Almeida Juliana Abranches, Liu Yanhong, Song Minho, Lee Jeong, Gaskins H, Maddox Carol, Osuna Orlando, Pettigrew James, Escherichia coli challenge and one type of smectite alter intestinal barrier of pigs, 10.1186/2049-1891-4-52
  19. Almond G and Monahan K, 2000. Water medication with antibiotics. Proceedings of the North Carolina Healthy Hogs Seminar.
  20. Alsamarai, World Journal of Pharmacy and Pharmaceutical Sciences (WJPPS), 4, 50 (2015)
  21. Alustiza Fabrisio, Bellingeri Romina, Picco Natalia, Motta Carlos, Grosso Maria C., Barbero Cesar A., Acevedo Diego F., Vivas Adriana, IgY against enterotoxigenic Escherichia coli administered by hydrogel-carbon nanotubes composites to prevent neonatal diarrhoea in experimentally challenged piglets, 10.1016/j.vaccine.2016.05.004
  22. Amachawadi R. G., Shelton N. W., Shi X., Vinasco J., Dritz S. S., Tokach M. D., Nelssen J. L., Scott H. M., Nagaraja T. G., Selection of Fecal Enterococci Exhibiting tcrB-Mediated Copper Resistance in Pigs Fed Diets Supplemented with Copper, 10.1128/aem.00364-11
  23. Amachawadi Raghavendra G., Scott H. Morgan, Vinasco Javier, Tokach Mike D., Dritz Steve S., Nelssen Jim L., Nagaraja Tiruvoor G., Effects of In-Feed Copper, Chlortetracycline, and Tylosin on the Prevalence of Transferable Copper Resistance Gene,tcrB, Among Fecal Enterococci of Weaned Piglets, 10.1089/fpd.2015.1961
  24. Andres Victor M., Davies Rob H., Biosecurity Measures to Control Salmonella and Other Infectious Agents in Pig Farms: A Review : Biosecurity measures review…, 10.1111/1541-4337.12137
  25. Annett C. B., Viste J. R., Chirino-Trejo M., Classen H. L., Middleton D. M., Simko E., Necrotic enteritis: Effect of barley, wheat and corn diets on proliferation of Clostridium perfringens type A, 10.1080/0307945021000024544
  26. ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 2013. Résapath – Réseau d’épidémiosurveillance de l'antibiorésistance des bactéries pathogènes animales. Available online:
  27. ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 2014. Assessment of the risks of emergence of antimicrobial resistance associated with modes of antibiotic use in the field of animal health. Available online:
  28. ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 2015a. Résapath – Réseau d’épidémiosurveillance de l'antibiorésistance des bactéries pathogènes animales. Available online:
  29. ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 2015b. Sales survey of Veterinary Medicinal Products containing Antimicrobials in France – 2014. Available online:
  30. ANSES (French Agency for Food, Environmental and Occupational Health & Safety), 2016. RESAPATH – French surveillance network for antimicrobial resistance in pathogenic bacteria of animal origin. 2014 Annual Report. Available online:
  31. ANTHONY F., ACAR J., FRANKLIN A., GUPTA R., NICHOLLS T.J., TAMURA Y., THOMPSON S., THRELFALL E.J., VOSE D.J., VAN VUUREN M., WHITE D.G., Antimicrobial resistance: responsible and prudent use of antimicrobial agents in veterinary medicine : -EN- -FR- -ES-, 10.20506/rst.20.3.1318
  32. Anthony T. Renée, Altmaier Ralph, Park Jae Hong, Peters Thomas M., Modeled Effectiveness of Ventilation with Contaminant Control Devices on Indoor Air Quality in a Swine Farrowing Facility, 10.1080/15459624.2013.875186
  33. Arnold Sandra R, Straus Sharon E, Interventions to improve antibiotic prescribing practices in ambulatory care, 10.1002/14651858.cd003539.pub2
  34. Arnold Craig B., Serra Pere, Piqué Alberto, Laser Direct-Write Techniques for Printing of Complex Materials, 10.1557/mrs2007.11
  35. Atterbury R. J., Hobley L., Till R., Lambert C., Capeness M. J., Lerner T. R., Fenton A. K., Barrow P., Sockett R. E., Effects of Orally Administered Bdellovibrio bacteriovorus on the Well-Being and Salmonella Colonization of Young Chicks, 10.1128/aem.00426-11
  36. Aumiller Tobias, Mosenthin Rainer, Weiss Eva, Potential of cereal grains and grain legumes in modulating pigs׳ intestinal microbiota – A review, 10.1016/j.livsci.2014.11.016
  37. Aviv Gili, Tsyba Katherine, Steck Natalie, Salmon-Divon Mali, Cornelius Antje, Rahav Galia, Grassl Guntram A, Gal-Mor Ohad, A unique megaplasmid contributes to stress tolerance and pathogenicity of an emergentSalmonella entericaserovar Infantis strain : The contribution of a megaplasmid to the emergence ofS. Infantis, 10.1111/1462-2920.12351
  38. Awad E, Austin B, Use of lupin,Lupinus perennis, mango,Mangifera indica, and stinging nettle,Urtica dioica, as feed additives to preventAeromonas hydrophilainfection in rainbow trout,Oncorhynchus mykiss(Walbaum), 10.1111/j.1365-2761.2009.01133.x
  39. Bae J.K., Wieland B., Sait M., Longbottom D., Smith D.G.E., Alarcon P., Wheelhouse N., Risk factors associated with Lawsonia intracellularis in English pig farms, 10.1016/j.tvjl.2013.03.020
  40. Baggott D., Casartelli A., Fraisse F., Manavella C., Marteau R., Rehbein S., Wiedemann M., Yoon S., Demonstration of the metaphylactic use of gamithromycin against bacterial pathogens associated with bovine respiratory disease in a multicentre farm trial, 10.1136/vr.c6776
  41. Bahar Ali, Ren Dacheng, Antimicrobial Peptides, 10.3390/ph6121543
  42. Bak Hanne, Rathkjen Poul, Reduced use of antimicrobials after vaccination of pigs against porcine proliferative enteropathy in a Danish SPF herd, 10.1186/1751-0147-51-1
  43. Bal A.M., Coombs G.W., Holden M.T.G., Lindsay J.A., Nimmo G.R., Tattevin P., Skov R.L., Genomic insights into the emergence and spread of international clones of healthcare-, community- and livestock-associated meticillin-resistant Staphylococcus aureus : Blurring of the traditional definitions, 10.1016/j.jgar.2016.04.004
  44. Baloch Abdul Rasheed, Zhang Xiao-Ying, Schade Rüdiger, IgY Technology in aquaculture - a review, 10.1111/raq.12059
  45. Bampidis V. A., Christodoulou V., Florou-Paneri P., Christaki E., Effect of Dried Oregano Leaves Versus Neomycin in Treating Newborn Calves with Colibacillosis, 10.1111/j.1439-0442.2006.00806.x
  46. Banhazi, International Journal of Agricultural and Biological Engineering, 5, 1 (2012)
  47. Baquero F., The 2010 Garrod Lecture: The dimensions of evolution in antibiotic resistance: ex unibus plurum et ex pluribus unum, 10.1093/jac/dkr214
  48. Barbosa Camilo, Venail Patrick, Holguin Angela V., Vives Martha J., Co-Evolutionary Dynamics of the Bacteria Vibrio sp. CV1 and Phages V1G, V1P1, and V1P2: Implications for Phage Therapy, 10.1007/s00248-013-0284-2
  49. Barbut Frédéric, Mario Nathalie, Delmée Michel, Gozian Joël, Genomic fingerprinting ofClostridium difficileisolates by using a random amplified polymorphic DNA (RAPD) assay, 10.1111/j.1574-6968.1993.tb06567.x
  50. Barnum, The Canadian Veterinary Journal, 2, 83 (1961)
  51. Barrett Damien J, More Simon J, Graham David A, O'Flaherty Joe, Doherty Michael L, Gunn H Michael, Considerations on BVD eradication for the Irish livestock industry, 10.1186/2046-0481-64-12
  52. Barrow P. A., Neto O. C. Freitas, Pullorum disease and fowl typhoid—new thoughts on old diseases: a review, 10.1080/03079457.2010.542575
  53. Batchelor Miranda, Hopkins Katie L., Liebana Ernesto, Slickers Peter, Ehricht Ralf, Mafura Muriel, Aarestrup Frank, Mevius Dik, Clifton-Hadley Felicity A., Woodward Martin J., Davies Rob H., Threlfall E. John, Anjum Muna F., Development of a miniaturised microarray-based assay for the rapid identification of antimicrobial resistance genes in Gram-negative bacteria, 10.1016/j.ijantimicag.2007.11.017
  54. Bates Janice, Jordens Zoe, Selkon J.B., Evidence for an animal origin of vancomycin-resistant enterococci, 10.1016/0140-6736(93)91613-q
  55. Batista C.G., Coelho S.G., Rabelo E., Lana A.M.Q., Carvalho A.U., Reis R.B., Saturnino H.M., Desempenho e saúde de bezerras alimentadas com leite sem resíduo de drogas antimicrobianas ou leite de vacas tratadas contra mastite adicionado ou não de probiótico, 10.1590/s0102-09352008000100026
  56. Beattie, Animal Welfare, 4, 207 (1995)
  57. Beattie V.E., Walker N., Sneddon I.A., An investigation of the effect of environmental enrichment and space allowance on the behaviour and production of growing pigs, 10.1016/0168-1591(96)01031-3
  58. Bednorz Carmen, Oelgeschläger Kathrin, Kinnemann Bianca, Hartmann Susanne, Neumann Konrad, Pieper Robert, Bethe Astrid, Semmler Torsten, Tedin Karsten, Schierack Peter, Wieler Lothar H., Guenther Sebastian, The broader context of antibiotic resistance: Zinc feed supplementation of piglets increases the proportion of multi-resistant Escherichia coli in vivo, 10.1016/j.ijmm.2013.06.004
  59. Beemer F, Velzen G, Berg C, Zunderdorp M, Lambrechts E, Gier K and Oud N 2010. What would be the effects of decoupling the prescription and sale of veterinary medicines by veterinarians? (Berenschot report). Available online:
  60. BelVetSac (Belgian Veterinary Surveillance of Antimicrobial Consumption), 2015. National consumption report 2014. Available online:
  61. Bennedsgaard Torben W, Thamsborg Stig M, Aarestrup Frank M, Enevoldsen Carsten, Vaarst Mette, Christoffersen Anna B, 10.1186/1751-0147-48-24
  62. Bertulat Sandra, Fischer-Tenhagen Carola, Heuwieser Wolfgang, A survey of drying-off practices on commercial dairy farms in northern Germany and a comparison to science-based recommendations, 10.1136/vetreco-2014-000068
  63. Beski, British Poultry Science, 56, 559 (2015)
  64. BESSEI W., Welfare of broilers: a review, 10.1079/wps2005108
  65. Bich Hang Bui Thi, Phuong Nguyen Thanh, Kestemont Patrick, Can immunostimulants efficiently replace antibiotic in striped catfish (Pangasianodon hypophthalmus) against bacterial infection by Edwardsiella ictaluri?, 10.1016/j.fsi.2014.08.007
  66. Biggs Andrew, Barrett David, Bradley Andrew, Green Martin, Reyher Kristen, Zadoks Ruth, Antibiotic dry cow therapy: where next?: TABLE 1:, 10.1136/vr.i338
  67. Bilkei, Tierarztliche Umschau, 66, 157 (2011)
  68. Bilkei, Tierarztliche Umschau, 66, 253 (2011)
  69. Bishop S.C., Genetic resistance to infections in sheep, 10.1016/j.vetmic.2015.07.013
  70. Blanco-Penedo I., López-Alonso M., Shore R. F., Miranda M., Castillo C., Hernández J., Benedito J. L., Evaluation of organic, conventional and intensive beef farm systems: health, management and animal production, 10.1017/s1751731112000298
  71. Boerlin P., Wissing A., Aarestrup F. M., Frey J., Nicolet J., Antimicrobial Growth Promoter Ban and Resistance to Macrolides and Vancomycin in Enterococci from Pigs, 10.1128/jcm.39.11.4193-4195.2001
  72. Bohm, Der Praktische Tierarzt, 97, 147 (2016)
  73. Bombyk R.A.M., Bykowski A.L., Draper C.E., Savelkoul E.J., Sullivan L.R., Wyckoff T.J.O., Comparison of types and antimicrobial susceptibility of Staphylococcus from conventional and organic dairies in west-central Minnesota, USA, 10.1111/j.1365-2672.2007.03681.x
  74. Bordin, Molecular Cancer Research, 2, 692 (2004)
  75. Bos Marian E. H., Taverne Femke J., van Geijlswijk Ingeborg M., Mouton Johan W., Mevius Dik J., Heederik Dick J. J., , Consumption of Antimicrobials in Pigs, Veal Calves, and Broilers in The Netherlands: Quantitative Results of Nationwide Collection of Data in 2011, 10.1371/journal.pone.0077525
  76. Bos Marian E. H., Mevius Dik J., Wagenaar Jaap A., van Geijlswijk Ingeborg M., Mouton Johan W., Heederik Dick J. J., Antimicrobial prescription patterns of veterinarians: introduction of a benchmarking approach: Figure 1., 10.1093/jac/dkv104
  77. Boutet, Annales de Médecine Vétérinaire, 149, 173 (2005)
  78. BPC (British Poultry Council), 2016. Leading the way in the responsible use of antibiotics ‐ The BPC antibiotic stewardship scheme. Available online:
  79. Bracke, Animal Welfare, 20, 347 (2011)
  80. Bradley A.J., Breen J.E., Payne B., White V., Green M.J., An investigation of the efficacy of a polyvalent mastitis vaccine using different vaccination regimens under field conditions in the United Kingdom, 10.3168/jds.2014-8332
  81. Bradshaw R. H., Parrott R. F., Forsling M. L., Goode J. A., Lloyd D. M., Rodway R. G., Broom D. M., Stress and travel sickness in pigs: effects of road transport on plasma concentrations of cortisol, beta-endorphin and lysine vasopressin, 10.1017/s135772980001540x
  82. Broens E, Transmission of methicillin-resistant Staphylococcus aureus from food production animals to humans: a review., 10.1079/pavsnnr20083095
  83. Broom D. M., Welfare assessment and welfare problem areas during handling and transport., Livestock handling and transport. ISBN:9780851994093 p.43-61, 10.1079/9780851994093.0043
  84. BROOM L.J., Organic acids for improving intestinal health of poultry, 10.1017/s0043933915002391
  85. BROWNLIE J., The pathogenesis of bovine virus diarrhoea virus infection : -EN- -FR- -ES-, 10.20506/rst.9.1.491
  86. Brscic M., Heutinck L.F.M., Wolthuis-Fillerup M., Stockhofe N., Engel B., Visser E.K., Gottardo F., Bokkers E.A.M., Lensink B.J., Cozzi G., Van Reenen C.G., Prevalence of gastrointestinal disorders recorded at postmortem inspection in white veal calves and associated risk factors, 10.3168/jds.2010-3480
  87. Bulfon Chiara, Volpatti Donatella, Galeotti Marco, Current research on the use of plant-derived products in farmed fish, 10.1111/are.12238
  88. Bunner Christine A., Norby Bo, Bartlett Paul C., Erskine Ronald J., Downes Frances P., Kaneene John B., Prevalence and pattern of antimicrobial susceptibility inEscherichia coliisolated from pigs reared under antimicrobial-free and conventional production methods, 10.2460/javma.231.2.275
  89. Burbank David R., Shah Devendra H., LaPatra Scott E., Fornshell Gary, Cain Kenneth D., Enhanced resistance to coldwater disease following feeding of probiotic bacterial strains to rainbow trout (Oncorhynchus mykiss), 10.1016/j.aquaculture.2011.09.004
  90. Burckhardt Irene, Zimmermann Stefan, Using Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry To Detect Carbapenem Resistance within 1 to 2.5 Hours, 10.1128/jcm.00287-11
  91. Burkey T. E., Dritz S. S., Nietfeld J. C., Johnson B. J., Minton J. E., Effect of dietary mannanoligosaccharide and sodium chlorate on the growth performance, acute-phase response, and bacterial shedding of weaned pigs challenged with serotype Typhimurium, 10.2527/2004.822397x
  92. Burow E and Käsbohrer A, 2016. Risk factors for antimicrobial resistance in Escherichia Coli in pigs receiving oral antimicrobial treatment: a systematic review. Microbial Drug Resistance, online ahead of print.
  93. Burow E., Simoneit C., Tenhagen B.-A., Käsbohrer A., Oral antimicrobials increase antimicrobial resistance in porcine E. coli – A systematic review, 10.1016/j.prevetmed.2013.12.007
  94. Burridge Les, Weis Judith S., Cabello Felipe, Pizarro Jaime, Bostick Katherine, Chemical use in salmon aquaculture: A review of current practices and possible environmental effects, 10.1016/j.aquaculture.2010.05.020
  95. Burt Sara, Essential oils: their antibacterial properties and potential applications in foods—a review, 10.1016/j.ijfoodmicro.2004.03.022
  96. Cabello Felipe C, Godfrey Henry P, Buschmann Alejandro H, Dölz Humberto J, Aquaculture as yet another environmental gateway to the development and globalisation of antimicrobial resistance, 10.1016/s1473-3099(16)00100-6
  97. Cagienard A., Regula G., Danuser J., The impact of different housing systems on health and welfare of grower and finisher pigs in Switzerland, 10.1016/j.prevetmed.2005.01.004
  98. Callens Bénédicte, Persoons Davy, Maes Dominiek, Laanen Maria, Postma Merel, Boyen Filip, Haesebrouck Freddy, Butaye Patrick, Catry Boudewijn, Dewulf Jeroen, Prophylactic and metaphylactic antimicrobial use in Belgian fattening pig herds, 10.1016/j.prevetmed.2012.03.001
  99. Caly Delphine L., D'Inca Romain, Auclair Eric, Drider Djamel, Alternatives to Antibiotics to Prevent Necrotic Enteritis in Broiler Chickens: A Microbiologist's Perspective, 10.3389/fmicb.2015.01336
  100. Campbell, Veterinary Clinics of North America: Food Animal Practice, 20, 39 (2004)
  101. Campos Joana, Cristino Luís, Peixe Luísa, Antunes Patrícia, MCR-1 in multidrug-resistant and copper-tolerant clinically relevantSalmonella1,4,[5],12:i:- andS. Rissen clones in Portugal, 2011 to 2015, 10.2807/
  102. Cannon, American Journal of Physiology‐Legacy Content, 33, 356 (1914)
  103. Cao L., Yang X. J., Li Z. J., Sun F. F., Wu X. H., Yao J. H., Reduced lesions in chickens with Clostridium perfringens-induced necrotic enteritis by Lactobacillus fermentum 1.2029, 10.3382/ps.2012-02548
  104. Cao Minh Duc, Ganesamoorthy Devika, Elliott Alysha G., Zhang Huihui, Cooper Matthew A., Coin Lachlan J.M., Streaming algorithms for identification of pathogens and antibiotic resistance potential from real-time MinIONTM sequencing, 10.1186/s13742-016-0137-2
  105. Carattoli A., Resistance Plasmid Families in Enterobacteriaceae, 10.1128/aac.01707-08
  106. Carlsson U., Wallgren P., Renström L. H. M., Lindberg A., Eriksson H., Thorén P., Eliasson-Selling L., Lundeheim N., Nörregard E., Thörn C., Elvander M., Emergence of Porcine Reproductive and Respiratory Syndrome in Sweden: Detection, Response and Eradication, 10.1111/j.1865-1682.2008.01065.x
  107. Casewell M., The European ban on growth-promoting antibiotics and emerging consequences for human and animal health, 10.1093/jac/dkg313
  108. Castro-Sánchez Enrique, Drumright Lydia N., Gharbi Myriam, Farrell Susan, Holmes Alison H., Mapping Antimicrobial Stewardship in Undergraduate Medical, Dental, Pharmacy, Nursing and Veterinary Education in the United Kingdom, 10.1371/journal.pone.0150056
  109. Catry Boudewijn, Threlfall John, Critically Important Antimicrobial—or Not?, 10.1086/648502
  110. CATRY B., VAN DUIJKEREN E., POMBA M. C., GREKO C., MORENO M. A., PYÖRÄLÄ S., RUŽAUSKAS M., SANDERS P., THRELFALL E. J., UNGEMACH F., TÖRNEKE K., MUŇOZ-MADERO C., TORREN-EDO J., Reflection paper on MRSA in food-producing and companion animals: epidemiology and control options for human and animal health, 10.1017/s0950268810000014
  111. Catry Boudewijn, Dewulf Jeroen, Maes Dominiek, Pardon Bart, Callens Benedicte, Vanrobaeys Mia, Opsomer Geert, de Kruif Aart, Haesebrouck Freddy, Effect of Antimicrobial Consumption and Production Type on Antibacterial Resistance in the Bovine Respiratory and Digestive Tract, 10.1371/journal.pone.0146488
  112. Çelik Elif, Ünver Ahmet, Isolation and Identification of Arcobacter spp. by Multiplex PCR from Water Sources in Kars Region, 10.1007/s00284-015-0883-x
  113. Chai Weidong, Zakrzewski Silke S, Günzel Dorothee, Pieper Robert, Wang Zhenya, Twardziok Sven, Janczyk Pawel, Osterrieder Nikolaus, Burwinkel Michael, High-dose dietary zinc oxide mitigates infection with transmissible gastroenteritis virus in piglets, 10.1186/1746-6148-10-75
  114. Chakraborty Suman Bhusan, Hancz Csaba, Application of phytochemicals as immunostimulant, antipathogenic and antistress agents in finfish culture : Phytochemicals in finfish culture, 10.1111/j.1753-5131.2011.01048.x
  115. Chang, Chinese Journal of Virology, 30, 441 (2014)
  116. Chantziaras I., Boyen F., Callens B., Dewulf J., Correlation between veterinary antimicrobial use and antimicrobial resistance in food-producing animals: a report on seven countries, 10.1093/jac/dkt443
  117. Chauvin Claire, Madec Fran�ois, Guillemot Didier, Sanders Pascal, The crucial question of standardisation when measuring drug consumption, 10.1051/vetres:2001145
  118. Checkley, The Canadian Veterinary Journal, 51, 853 (2010)
  119. Chi Junwook, Weersink Alfons, VanLeeuwen John A., Keefe Gregory P., The Economics of Controlling Infectious Diseases on Dairy Farms, 10.1111/j.1744-7976.2002.tb00335.x
  120. Cho Seongbeom, Fossler Charles P., Diez-Gonzalez Francisco, Wells Scott J., Hedberg Craig W., Kaneene John B., Ruegg Pamela L., Warnick Lorin D., Bender Jeffrey B., Antimicrobial Susceptibility of Shiga Toxin-ProducingEscherichia coliIsolated from Organic Dairy Farms, Conventional Dairy Farms, and County Fairs in Minnesota, 10.1089/fpd.2006.0074
  121. Chowdhury S., Sandberg M., Themudo G. E., Ersboll A. K., Risk factors for Campylobacter infection in Danish broiler chickens, 10.3382/ps.2012-02412
  122. Cicconi-Hogan K.M., Belomestnykh N., Gamroth M., Ruegg P.L., Tikofsky L., Schukken Y.H., Short communication: Prevalence of methicillin resistance in coagulase-negative staphylococci and Staphylococcus aureus isolated from bulk milk on organic and conventional dairy farms in the United States, 10.3168/jds.2013-7523
  123. Codex Alimentarius , 2016. Joint FAO/WHO Food Standards Programme ‐ 71st Session FAO Headquarters, Rome, Italy, 20‐23 June 2016. CODEX work on antimicrobial resistance. CX/EXEC 16/71/3 April 2016.
  124. Cohen Stuart James, van den Munckhof Thijs, Voets Guido, Scharringa Jelle, Fluit Ad, Hall Maurine Leverstein-Van, Comparison of ESBL contamination in organic and conventional retail chicken meat, 10.1016/j.ijfoodmicro.2011.12.034
  125. Cohn Leah A., Middleton John R., A veterinary perspective on methicillin-resistant staphylococci, 10.1111/j.1476-4431.2009.00497.x
  126. Cole Dana, Todd Lori, Wing Steve, Concentrated Swine Feeding Operations and Public Health: A Review of Occupational and Community Health Effects, 10.1289/ehp.00108685
  127. Collado Luis, Inza Isabel, Guarro Josep, Figueras Maria Jose, Presence of Arcobacter spp. in environmental waters correlates with high levels of fecal pollution : Correlation of Arcobacter with fecal pollution, 10.1111/j.1462-2920.2007.01555.x
  128. Collignon Peter, Powers John H., Chiller Tom M., Aidara‐Kane Awa, Aarestrup Frank M., World Health Organization Ranking of Antimicrobials According to Their Importance in Human Medicine: A Critical Step for Developing Risk Management Strategies for the Use of Antimicrobials in Food Production Animals, 10.1086/599374
  129. Collignon Peter, Aarestrup Frank M., Irwin Rebecca, McEwen Scott, Human Deaths and Third-Generation Cephalosporin use in Poultry, Europe, 10.3201/eid1908.120681
  130. Cook Nigel B., Nordlund Kenneth V., The influence of the environment on dairy cow behavior, claw health and herd lameness dynamics, 10.1016/j.tvjl.2007.09.016
  131. Cooper Caitlin A., Garas Klobas Lydia C., Maga Elizabeth A., Murray James D., Consuming Transgenic Goats' Milk Containing the Antimicrobial Protein Lysozyme Helps Resolve Diarrhea in Young Pigs, 10.1371/journal.pone.0058409
  132. Cota Ignacio, Sánchez-Romero María Antonia, Hernández Sara B., Pucciarelli M. Graciela, García-del Portillo Francisco, Casadesús Josep, Epigenetic Control of Salmonella enterica O-Antigen Chain Length: A Tradeoff between Virulence and Bacteriophage Resistance, 10.1371/journal.pgen.1005667
  133. Coyne L. A., Pinchbeck G. L., Williams N. J., Smith R. F., Dawson S., Pearson R. B., Latham S. M., Understanding antimicrobial use and prescribing behaviours by pig veterinary surgeons and farmers: a qualitative study, 10.1136/vr.102686
  134. Coyne L. A., Latham S. M., Williams N. J., Dawson S., Donald I. J., Pearson R. B., Smith R. F., Pinchbeck G. L., Understanding the culture of antimicrobial prescribing in agriculture: a qualitative study of UK pig veterinary surgeons, 10.1093/jac/dkw300
  135. Cozzi Giulio, Brscic Marta, Gottardo Flaviana, Main critical factors affecting the welfare of beef cattle and veal calves raised under intensive rearing systems in Italy: a review, 10.4081/ijas.2009.s1.67
  136. Craven S. E., Stern N. J., Cox N. A., Bailey J. S., Berrang M., Cecal Carriage of Clostridium perfringens in Broiler Chickens Given Mucosal Starter Culture [Trademark], 10.2307/1592646
  137. Cruz‐Papa, Philippine Agricultural Scientist, 97, 96 (2014)
  138. Cui S., Ge B., Zheng J., Meng J., Prevalence and Antimicrobial Resistance of Campylobacter spp. and Salmonella Serovars in Organic Chickens from Maryland Retail Stores, 10.1128/aem.71.7.4108-4111.2005
  139. Cummins Joseph M., Guthrie Dan, Hutcheson David P., Krakowka Steven, Rosenquist Bruce D., Natural Human Interferon-alpha Administered Orally as a Treatment of Bovine Respiratory Disease Complex, 10.1089/107999099313442
  140. D'Eath Richard B., Tolkamp Bert J., Kyriazakis Ilias, Lawrence Alistair B., ‘Freedom from hunger’ and preventing obesity: the animal welfare implications of reducing food quantity or quality, 10.1016/j.anbehav.2008.10.028
  141. da Silva, Semina: Ciências Agrárias, 28, 739 (2007)
  142. Dalmasso Guillaume, Nguyen Hang Thi Thu, Yan Yutao, Charrier-Hisamuddin Laetitia, Sitaraman Shanthi V., Merlin Didier, Butyrate Transcriptionally Enhances Peptide Transporter PepT1 Expression and Activity, 10.1371/journal.pone.0002476
  143. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2007. DANMAP 2006 – use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, foods and humans in Denmark. ISSN 1600‐2032. Available online:
  144. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2009a. DANMAP 2008 ‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, foods and humans in Denmark. ISSN 1600‐2032. Available online: 1600‐2032
  145. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2009b. DANMAP 2009 ‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, foods and humans in Denmark. ISSN 1600‐2032. Available online:
  146. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2011. DANMAP 2010‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. ISSN 1600‐2032. Available online:
  147. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2014. DANMAP 2013 ‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. ISSN 1600‐2032. Available online:
  148. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2015. DANMAP 2014 ‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. ISSN 1600‐2032. Available online:
  149. DANMAP (Danish Integrated Antimicrobial Resistance Monitoring and Research Programme), 2016. DANMAP 2015 ‐ use of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from food animals, food and humans in Denmark. ISSN 1600‐2032. Available online:
  150. Dargatz David A., Marshall Katherine L., Fedorka-Cray Paula J., Erdman Matthew M., Kopral Christine A., SalmonellaPrevalence and Antimicrobial Susceptibility from the National Animal Health Monitoring System Sheep 2011 Study, 10.1089/fpd.2015.2016
  151. Davies G., Genini S., Bishop S. C., Giuffra E., An assessment of opportunities to dissect host genetic variation in resistance to infectious diseases in livestock, 10.1017/s1751731108003522
  152. De Briyne N., Atkinson J., Pokludová L., Borriello S. P., Price S., Factors influencing antibiotic prescribing habits and use of sensitivity testing amongst veterinarians in Europe, 10.1136/vr.101454
  153. De Briyne N., Atkinson J., Borriello S. P., Pokludová L., Antibiotics used most commonly to treat animals in Europe, 10.1136/vr.102462
  154. de Jong A., Thomas V., Klein U., Marion H., Moyaert H., Simjee S., Vallé M., Pan-European resistance monitoring programmes encompassing food-borne bacteria and target pathogens of food-producing and companion animals, 10.1016/j.ijantimicag.2012.11.004
  155. de Jong IC, Bondt N, Ge L, Puister L, van den Heuvel H and Lourens A, 2013b. Reduction in antibiotic usage in broilers: side effects and best practices. Report 678. Wageningen UR Livestock Research.
  156. de Jong Anno, Thomas Valérie, Simjee Shabbir, Moyaert Hilde, El Garch Farid, Maher Kirsty, Morrissey Ian, Butty Pascal, Klein Ulrich, Marion Hervé, Rigaut Delphine, Vallé Michel, Antimicrobial susceptibility monitoring of respiratory tract pathogens isolated from diseased cattle and pigs across Europe: The VetPath study, 10.1016/j.vetmic.2014.04.008
  157. De Jonge Francien H., Bokkers E.A.M., Schouten W.G.P., Helmond F.A., Rearing piglets in a poor environment: Developmental aspects of social stress in pigs, 10.1016/s0031-9384(96)80009-6
  158. de Lange C.F.M., Pluske J., Gong J., Nyachoti C.M., Strategic use of feed ingredients and feed additives to stimulate gut health and development in young pigs, 10.1016/j.livsci.2010.06.117
  159. DeDonder K. D., Apley M. D., Li M., Gehring R., Harhay D. M., Lubbers B. V., White B. J., Capik S. F., KuKanich B., Riviere J. E., Tessman R. K., Pharmacokinetics and pharmacodynamics of gamithromycin in pulmonary epithelial lining fluid in naturally occurring bovine respiratory disease in multisource commingled feedlot cattle, 10.1111/jvp.12267
  160. Dewaele I., Rasschaert G., Wildemauwe C., Van Meirhaeghe H., Vanrobaeys M., De Graef E., Herman L., Ducatelle R., Heyndrickx M., De Reu K., Polyphasic characterization of Salmonella Enteritidis isolates on persistently contaminated layer farms during the implementation of a national control program with obligatory vaccination: A longitudinal study, 10.3382/ps.2012-02218
  161. Diarra Moussa S., Malouin François, Antibiotics in Canadian poultry productions and anticipated alternatives, 10.3389/fmicb.2014.00282
  162. Dibner J. J., Richards J. D., Antibiotic growth promoters in agriculture: history and mode of action, 10.1093/ps/84.4.634
  163. Dierikx Cindy M., Hengeveld Paul D., Veldman Kees T., de Haan Angela, van der Voorde Sanne, Dop Petra Y., Bosch Thijs, van Duijkeren Engeline, Ten years later: still a high prevalence of MRSA in slaughter pigs despite a significant reduction in antimicrobial usage in pigs the Netherlands, 10.1093/jac/dkw190
  164. Dieste-Pérez L., Frankena K., Blasco J.M., Muñoz P.M., de Jong M.C.M., Efficacy of antibiotic treatment and test-based culling strategies for eradicating brucellosis in commercial swine herds, 10.1016/j.prevetmed.2016.01.033
  165. DiGiandomenico Antonio, Sellman Bret R, Antibacterial monoclonal antibodies: the next generation?, 10.1016/j.mib.2015.07.014
  166. Dingle Tanis C., Butler-Wu Susan M., MALDI-TOF Mass Spectrometry for Microorganism Identification, 10.1016/j.cll.2013.03.001
  167. Diraviyam Thirumalai, Zhao Bin, Wang Yuan, Schade Ruediger, Michael Antonysamy, Zhang Xiaoying, Effect of Chicken Egg Yolk Antibodies (IgY) against Diarrhea in Domesticated Animals: A Systematic Review and Meta-Analysis, 10.1371/journal.pone.0097716
  168. Dischinger Jasmin, Basi Chipalu Shradha, Bierbaum Gabriele, Lantibiotics: Promising candidates for future applications in health care, 10.1016/j.ijmm.2013.09.003
  169. Doeschl‐Wilson AB, Bishop SC, Kyriazakis I and Villanueva B, 2012. Novel methods for quantifying individual host response to infectious pathogens for genetic analyses. Should we aim for genetic improvement in host resistance or tolerance to infectious disease?, 18.
  170. Dohms John E., Metz Alan, Stress — mechanisms of immunosuppression, 10.1016/0165-2427(91)90011-z
  171. Domer, Journal of the American Association for Laboratory Animal Science, 51, 162 (2012)
  172. Dorado-García Alejandro, Dohmen Wietske, Bos Marian E.H., Verstappen Koen M., Houben Manon, Wagenaar Jaap A., Heederik Dick J.J., Dose-Response Relationship between Antimicrobial Drugs and Livestock-Associated MRSA in Pig Farming1, 10.3201/eid2106.140706
  173. Dorado-García Alejandro, Graveland Haitske, Bos Marian E. H., Verstappen Koen M., Van Cleef Brigitte A. G. L., Kluytmans Jan A. J. W., Wagenaar Jaap A., Heederik Dick J. J., Effects of Reducing Antimicrobial Use and Applying a Cleaning and Disinfection Program in Veal Calf Farming: Experiences from an Intervention Study to Control Livestock-Associated MRSA, 10.1371/journal.pone.0135826
  174. Dowdle, Bulletin of the World Health Organization, 76, 22 (1998)
  175. du Marchie Sarvaas, International Animal Health Journal, 2, 26 (2015)
  176. Dumas S. E., French H. M., Lavergne S. N., Ramirez C. R., Brown L. J., Bromfield C. R., Garrett E. F., French D. D., Aldridge B. M., Judicious use of prophylactic antimicrobials to reduce abdominal surgical site infections in periparturient cows: part 1 – a risk factor review, 10.1136/vr.i103677
  177. Dunlop R.H, McEwen S.A, Meek A.H, Clarke R.C, Black W.D, Friendship R.M, Associations among antimicrobial drug treatments and antimicrobial resistance of fecal Escherichia coli of swine on 34 farrow-to-finish farms in Ontario, Canada, 10.1016/s0167-5877(97)00095-0
  178. Dupont, Acta Veterinaria Scandinavica, 58, 1 (2016)
  179. Dutch Ministry of Economic Affairs , 2014. Reduced and Responsible: use of antibiotics in food‐producing animals in the Netherlands.
  180. Dutil Lucie, Irwin Rebecca, Finley Rita, Ng Lai King, Avery Brent, Boerlin Patrick, Bourgault Anne-Marie, Cole Linda, Daignault Danielle, Desruisseau Andrea, Demczuk Walter, Hoang Linda, Horsman Greg B., Ismail Johanne, Jamieson Frances, Maki Anne, Pacagnella Ana, Pillai Dylan R., Ceftiofur Resistance inSalmonella entericaSerovar Heidelberg from Chicken Meat and Humans, Canada, 10.3201/eid1601.090729
  181. EC (European Commission), 2010. Evaluation of the EU Legislative Framework in the Field of Medicated Feed. Framework Contract for evaluation and evaluation related services ‐ Lot 3: Food Chain (awarded through tender no 2004/S 243‐208899) Final report. Available online:
  182. ECDC (European Centre for Disease Prevention and Control), 2016. Rapid Risk Assessment ‐ Plasmid‐mediated colistin resistance in Enterobacteriaceae. Available online:
  183. ECDC and EFSA, EFSA Journal, 9, 2154 (2011)
  184. ECDC and EFSA, EFSA Journal, 13, 4036 (2015)
  185. ECDC and EFSA, EFSA Journal, 14, 4380 (2016)
  186. ECDC, EFSA, EMA and SCENIHR (European Centre for Disease Prevention and Control, European Food Safety Authority, European Medicines Agency, Scientific Committee on Emerging and Newly Identified Health Risks), 2009. Joint Opinion on antimicrobial resistance (AMR) focused on zoonotic infections.
  187. , , , ECDC/EFSA/EMA first joint report on the integrated analysis of the consumption of antimicrobial agents and occurrence of antimicrobial resistance in bacteria from humans and food-producing animals : Joint Interagency Antimicrobial Consumption and Resistance Analysis (JIACRA) Report, 10.2903/j.efsa.2015.4006
  188. ECDC, EFSA and EMEA (European Centre for Disease Prevention and Control, European Food Safety Authority and European Medicines Agency), 2009. Joint scientific report of ECDC, EFSA and EMEA on meticillin resistant Staphylococcus aureus (MRSA) in livestock, companion animals and food. EFSA‐Q‐2009‐00612 ((EFSA Scientific Report 2009) 301, 1‐10) and EMEA/CVMP/SAGAM/62464/2009
  189. Edel W., Salmonella enteritidis eradication programme in poultry breeder flocks in The Netherlands, 10.1016/0168-1605(94)90209-7
  190. Edwards, Veterinary Clinics of North America: Food Animal Practice, 26, 273 (2010)
  191. , Technical specifications for the analysis and reporting of data on antimicrobial resistance (AMR) in the European Union Summary Report : Technical specifications for the analysis and reporting of data on AMR in the EU Summary Report, 10.2903/j.efsa.2012.2587
  192. , Scientific Opinion Concerning the Welfare of Animals during Transport : Welfare of Animals during Transport, 10.2903/j.efsa.2011.1966
  193. , Statement on the use of animal‐based measures to assess the welfare of animals, 10.2903/j.efsa.2012.2767
  194. , Scientific Opinion on the use of animal-based measures to assess welfare in pigs : Animal welfare measures - pigs, 10.2903/j.efsa.2012.2512
  195. , Scientific Opinion on the public health risks of bacterial strains producing extended-spectrum β-lactamases and/or AmpC β-lactamases in food and food-producing animals : ESBL/AmpC in food-producing animals and foods, 10.2903/j.efsa.2011.2322
  196. , Scientific Opinion on Carbapenem resistance in food animal ecosystems : Carbapenem resistance in food animal ecosystems, 10.2903/j.efsa.2013.3501
  197. , Ricci Antonia, Allende Ana, Bolton Declan, Chemaly Marianne, Davies Robert, Fernández Escámez Pablo Salvador, Girones Rosina, Koutsoumanis Kostas, Lindqvist Roland, Nørrung Birgit, Robertson Lucy, Ru Giuseppe, Sanaa Moez, Simmons Marion, Skandamis Panagiotis, Snary Emma, Speybroeck Niko, Kuile Benno Ter, Threlfall John, Wahlström Helene, Bengtsson Björn, Bouchard Damien, Randall Luke, Tenhagen Bernd‐Alois, Verdon Eric, Wallace John, Brozzi Rosella, Guerra Beatriz, Liebana Ernesto, Stella Pietro, Herman Lieve, Risk for the development of Antimicrobial Resistance (AMR) due to feeding of calves with milk containing residues of antibiotics, 10.2903/j.efsa.2017.4665
  198. , Scientific Opinion on the safety and efficacy of the product Cylactin® (Enterococcus faecium) as a feed additive for chickens for fattening : Cylactin® for chickens for fattening, 10.2903/j.efsa.2010.1661
  199. , Scientific Opinion on the safety and efficacy ofLactobacillus pentosus(DSM 14025) as a silage additive for all animal species : Lactobacillus pentosus DSM 14025 for all species, 10.2903/j.efsa.2011.2449
  200. , Guidance on the assessment of bacterial susceptibility to antimicrobials of human and veterinary importance, 10.2903/j.efsa.2012.2740
  201. , Scientific Opinion on the safety and efficacy of copper compounds (E4) as feed additives for all animal species: cupric sulphate pentahydrate based on a dossier submitted by Manica S.p.A. : Cupric sulphate pentahydrate for all species, 10.2903/j.efsa.2012.2969
  202. , Scientific Opinion on Toyocerin®(Bacillus cereus) as a feed additive for sows, piglets, pigs for fattening, cattle for fattening, calves for rearing, chickens for fattening and rabbits for fattening : Toyocerin® for several species, 10.2903/j.efsa.2012.2924
  203. , Scientific Opinion on the safety and efficacy of Pediococcus pentosaceus (NCIMB 30044) as a silage additive for all animal species, 10.2903/j.efsa.2014.3610
  204. , Scientific Opinion on the safety and efficacy of Pediococcus pentosaceus (NCIMB 30068) as a silage additive for all animal species, 10.2903/j.efsa.2014.3609
  205. , Scientific Opinion on the safety and efficacy of Toyocerin® (Bacillus toyonensis) as a feed additive for chickens for fattening, weaned piglets, pigs for fattening, sows for reproduction, cattle for fattening and calves for rearing and for rabbits for fat : Toyocerin® for several species, 10.2903/j.efsa.2014.3766
  206. , Revision of the currently authorised maximum copper content in complete feed, 10.2903/j.efsa.2016.4563
  207. , Rychen Guido, Aquilina Gabriele, Azimonti Giovanna, Bampidis Vasileios, De Lourdes Bastos Maria, Bories Georges, Chesson Andrew, Cocconcelli Pier Sandro, Flachowsky Gerhard, Gropp Jürgen, Kolar Boris, Kouba Maryline, Lopez Puente Secundino, Lopez‐Alonso Marta, Mantovani Alberto, Mayo Baltasar, Ramos Fernando, Villa Roberto Edoardo, Wallace Robert John, Wester Pieter, Brozzi Rosella, Saarela Maria, Safety and efficacy of Lactobacillus brevis NCIMB 42149 as a silage additive for all animal species, 10.2903/j.efsa.2016.4616
  208. Einarsson Stig, Madej Andrzej, Tsuma Victor, The influence of stress on early pregnancy in the pig, 10.1016/0378-4320(96)01516-3
  209. Ekkel E D, van Doorn C E, Hessing M J, Tielen M J, The Specific-Stress-Free housing system has positive effects on productivity, health, and welfare of pigs., 10.2527/1995.7361544x
  210. Ekperigin H. E., Jang S., McCapes R. H., Effective Control of a Gentamicin-Resistant Salmonella arizonae Infection in Turkey Poults, 10.2307/1590326
  211. Pérez-Cobas Ana Elena, Gosalbes María José, Friedrichs Anette, Knecht Henrik, Artacho Alejandro, Eismann Kathleen, Otto Wolfgang, Rojo David, Bargiela Rafael, von Bergen Martin, Neulinger Sven C, Däumer Carolin, Heinsen Femke-Anouska, Latorre Amparo, Barbas Coral, Seifert Jana, dos Santos Vitor Martins, Ott Stephan J, Ferrer Manuel, Moya Andrés, Gut microbiota disturbance during antibiotic therapy: a multi-omic approach, 10.1136/gutjnl-2012-303184
  212. Elizondo Ana M., Mercado Elsa C., Rabinovitz Bettina C., Fernandez-Miyakawa Mariano E., Effect of tannins on the in vitro growth of Clostridium perfringens, 10.1016/j.vetmic.2010.04.003
  213. Ellis Kathryn A, Innocent Giles T, Mihm Monika, Cripps Peter, McLean W Graham, Howard C Vyvyan, Grove-White Dai, Dairy cow cleanliness and milk quality on organic and conventional farms in the UK, 10.1017/s002202990700249x
  214. Elwinger, Acta Veterinaria Scandinavica, 33, 369 (1992)
  215. EMEA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2009. Recommendation on the evaluation of the benefit ‐ Risk balance of veterinary medicinal products. Available online:
  216. EMA (European Medicines Agency), 2013a. Use of colistin products in animals within the European Union: development of resistance and possible impact on human and animal health (EMA/755938/2012). Available online:
  217. EMA (European Medicines Agency), 2013b. Use of glycylcyclines in animals in the European Union: development of resistance and possible impact on human and animal health (EMA/291760/2013). Available online:
  218. EMA (European Medicines Agency), 2014. Answers to the requests for scientific advice on the impact on public health and animal health of the use of antibiotics in animals – Answer to the second request from the EC (ranking of antibiotics); Answer to the third request from the EC (new antibiotics); Answer to the fourth request from the EC (risk mitigation options) (EMA/381884/2014). Available online:
  219. EMA (European Medicines Agency), 2015. Workshop on the therapeutic use of bacteriophages (EMA/389257/2015). Available online:
  220. EMA (European Medicines Agency), 2016a. Guideline for the demonstration of efficacy for veterinary medicinal products containing antimicrobial substances (EMA/CVMP/627/2001‐Rev.1). Available online:
  221. EMA (European Medicines Agency), 2016b. Updated advice on the use of colistin products in animals within the European Union: development of resistance and possible impact on human and animal health (EMA/CVMP/CHMP/231573/2016). Available online:
  222. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2010. Opinion following an Article 35 referral for all veterinary medicinal products containing quinolones including fluoroquinolones intended for use in food‐producing species. Available online:
  223. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2011. Reflection paper on the use of macrolides, lincosamides and streptogramins (MLS) in food‐producing animals in the European Union: development of resistance and impact on human and animal health. Available online:
  224. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2012a. Opinion following an Article 35 referral for all veterinary medicinal products containing systemically administered (parenteral and oral) 3rd and 4th generation cephalosporins intended for use in food producing species. Available online:
  225. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2012b. Refusal EPAR for Naxcel ‐ Type II variation (EMEA/V/C/000079/II/0013) ‐ EMA/CVMP/746112/2012. Available online:
  226. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2014a. CVMP assessment report for Bovela (EMEA/V/C/003703/0000). Available online:
  227. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2014b. Opinion following an Article 35 referral for all veterinary medicinal products containing enrofloxacin to be administered via the drinking water to chickens and/or turkeys. Available online:
  228. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2014c. Opinion following an Article 35 referral for veterinary medicinal products containing tylosin to be administered orally via feed or the drinking water to pigs. Available online:
  229. EMA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2016. CLYNAV ‐ Common name: Salmon pancreas disease vaccine (recombinant DNA plasmid) (EMA/CVMP/223807/2016). Available online:
  230. EMA CVMP AWP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use, Antimicrobials Working Party), 2015. Guideline on the assessment of the risk to public health from antimicrobial resistance due to the use of an antimicrobial veterinary medicinal product in food‐producing animals. Available online:
  231. EMA ESVAC (European Medicines Agency, European Surveillance of Veterinary Antimicrobial Consumption), 2013. Revised ESVAC reflection paper on collecting data on consumption of antimicrobial agents per animal species, on technical units of measurement and indicators for reporting consumption of antimicrobial agents in animals (EMA/286416/2012‐Rev.1). Available online:
  232. EMA ESVAC (European Medicines Agency, European Surveillance of Veterinary Antimicrobial Consumption), 2015a. Principles on assignment of defined daily dose for animals (DDDA) and defined course dose for animals (DCDA) (EMA/710019/2014). Available online:
  233. EMA ESVAC (European Medicines Agency, European Surveillance of Veterinary Antimicrobial Consumption), 2015b. Sales of veterinary antimicrobial agents in 26 EU/EEA countries in 2013 (EMA/387934/2015). Fifth ESVAC report. Available online:
  234. EMA ESVAC (European Medicines Agency, European Surveillance of Veterinary Antimicrobial Consumption), 2016. Sales of veterinary antimicrobial agents in 29 EU/EEA countries in 2014 (EMA/61769/2016). Trends from 2011 to 2014. Sixth ESVAC report. Available online:
  235. EMEA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2006. Reflection paper on the use of fluoroquinolones in food producing animals ‐ Precautions for use in the SPC regarding prudent use guidance (EMEA/CVMP/416168/2006‐FINAL). Available online:
  236. EMEA CVMP (European Medicines Agency, Committee for Medicinal Products for Veterinary Use), 2009. Revised reflection paper on the use of 3rd and 4th generation cephalosporins in food producing animals in the European Union: development of resistance and impact on human and animal health (EMEA/CVMP/SAGAM/81730/2006‐Rev.1). Available online:
  237. EMEA CVMP SAGAM (European Medicines Agency, Committee for Medicinal Products for Veterinary Use, Scientific Advisory Group on Antimicrobials), 2008. Reflection paper on Antimicrobial Resistance Surveillance as Post‐marketing Authorisation Commitment (EMEA/CVMP/SAGAM/428938/2007). Available online:
  238. Enøe Claes, Mousing Jan, Schirmer Anna Luise, Willeberg Preben, Infectious and rearing-system related risk factors for chronic pleuritis in slaughter pigs, 10.1016/s0167-5877(02)00029-6
  239. ERNST K, TUCHSCHERER M, KANITZ E, PUPPE B, MANTEUFFEL G, Effects of attention and rewarded activity on immune parameters and wound healing in pigs, 10.1016/j.physbeh.2006.07.001
  240. Etterlin Pernille Engelsen, Ytrehus Bjørnar, Lundeheim Nils, Heldmer Eva, Österberg Julia, Ekman Stina, Effects of free-range and confined housing on joint health in a herd of fattening pigs, 10.1186/s12917-014-0208-5
  241. Evans Scott R., Hujer Andrea M., Jiang Hongyu, Hujer Kristine M., Hall Thomas, Marzan Christine, Jacobs Michael R., Sampath Rangarajan, Ecker David J., Manca Claudia, Chavda Kalyan, Zhang Pan, Fernandez Helen, Chen Liang, Mediavilla Jose R., Hill Carol B., Perez Federico, Caliendo Angela M., Fowler Vance G., Chambers Henry F., Kreiswirth Barry N., Bonomo Robert A., Rapid Molecular Diagnostics, Antibiotic Treatment Decisions, and Developing Approaches to Inform Empiric Therapy: PRIMERS I and II, 10.1093/cid/civ837
  242. Ewbank R., Bryant M.J., Aggressive behaviour amongst groups of domesticated pigs kept at various stocking rates, 10.1016/s0003-3472(72)80169-6
  243. Fall N., Emanuelson U., Martinsson K., Jonsson S., Udder health at a Swedish research farm with both organic and conventional dairy cow management, 10.1016/j.prevetmed.2007.07.003
  244. FAO (Food and Agriculture Organization), 2015. Report of the conference of FAO ‐ Thirty‐ninth Session ‐ Rome, 6‐13 June 2015 ‐ Resolution 4/2015: Antimicrobial Resistance. Available online:
  245. FAO (Food and Agriculture Organization), 2016. Drivers, dynamics and epidemiology of antimicrobial resistance in animal production. Wall B.A., Mateus A., Marshall L., Pfeiffer D.U., Lubroth J., Ormel H.J., Otto P., Patriarchi A. Food and Agriculture Organization of the United Nations, Rome, Italy. Available online:
  246. Fasina Yewande O., Newman Molli M., Stough Joshua M., Liles Mark R., Effect ofClostridium perfringensinfection and antibiotic administration on microbiota in the small intestine of broiler chickens, 10.3382/ps/pev329
  247. FDA (Food and Drug Administration), 2015. NARMS Integrated Report: 2012‐2013 ‐ The National Antimicrobial Resistance Monitoring System: Enteric Bacteria. Available online:
  248. Feltrin Fabiola, Alba Patricia, Kraushaar Britta, Ianzano Angela, Argudín María Angeles, Di Matteo Paola, Porrero María Concepción, Aarestrup Frank M., Butaye Patrick, Franco Alessia, Battisti Antonio, A Livestock-Associated, Multidrug-Resistant, Methicillin-Resistant Staphylococcus aureus Clonal Complex 97 Lineage Spreading in Dairy Cattle and Pigs in Italy, 10.1128/aem.02854-15
  249. Fertner Mette, Boklund Anette, Dupont Nana, Toft Nils, Changes in group treatment procedures of Danish finishers and its influence on the amount of administered antimicrobials, 10.1016/j.prevetmed.2016.01.034
  250. Field Des, Cotter Paul D., Hill Colin, Ross R. P., Bioengineering Lantibiotics for Therapeutic Success, 10.3389/fmicb.2015.01363
  251. Filippitzi, Vlaams Diergeneeskundig Tijdschrift, 83, 215 (2014)
  252. Fontana Ilaria, Tullo Emanuela, Butterworth Andy, Guarino Marcella, An innovative approach to predict the growth in intensive poultry farming, 10.1016/j.compag.2015.10.001
  253. Fontana, Animal, 1 (2015)
  254. Fosse J., Seegers H., Magras C., Prevalence and Risk Factors for Bacterial Food-Borne Zoonotic Hazards in Slaughter Pigs: A Review, 10.1111/j.1863-2378.2008.01185.x
  255. Fossi, Animal Health Research Reviews, 2, 53 (2001)
  256. FRANKLIN A., ACAR J., ANTHONY F., GUPTA R., NICHOLLS T.J., TAMURA Y., THOMPSON S., THRELFALL E.J., VOSE D.J., VAN VUUREN M., WHITE D.G., WEGENER H.C., COSTARRICA M.L., Antimicrobial resistance: harmonisation of national antimicrobial resistance monitoring and surveillance programmes in animals and in animal-derived food : -EN- -FR- -ES-, 10.20506/rst.20.3.1315
  257. Fraqueza M. J., Martins A., Borges A. C., Fernandes M. H., Fernandes M. J., Vaz Y., Bessa R. J. B., Barreto A. S., Antimicrobial resistance among Campylobacter spp. strains isolated from different poultry production systems at slaughterhouse level, 10.3382/ps.2013-03729
  258. Fray M.D, Paton D.J, Alenius S, The effects of bovine viral diarrhoea virus on cattle reproduction in relation to disease control, 10.1016/s0378-4320(00)00082-8
  259. Fregonesi Jose A, Leaver J.David, Influence of space allowance and milk yield level on behaviour, performance and health of dairy cows housed in strawyard and cubicle systems, 10.1016/s0301-6226(02)00097-0
  260. Fregonesi J.A., Tucker C.B., Weary D.M., Overstocking Reduces Lying Time in Dairy Cows, 10.3168/jds.2006-794
  261. Gadde U., Rathinam T., Lillehoj Hyun S., Passive immunization with hyperimmune egg-yolk IgY as prophylaxis and therapy for poultry diseases – A review, 10.1017/s1466252315000195
  262. Gallois M., Rothkötter H. J., Bailey M., Stokes C. R., Oswald I. P., Natural alternatives to in-feed antibiotics in pig production: can immunomodulators play a role?, 10.1017/s1751731109004236
  263. Galyean M L, Perino L J, Duff G C, Interaction of cattle health/immunity and nutrition., 10.2527/1999.7751120x
  264. Garcia Arlene, Sutherland Mhairi, Pirner Glenna, Picinin Guilherme, May Matthew, Backus Brittany, McGlone John, Impact of Providing Feed and/or Water on Performance, Physiology, and Behavior of Weaned Pigs during a 32-h Transport, 10.3390/ani6050031
  265. Garmo Randi T, Waage Steinar, Sviland Stale, Henriksen Britt IF, Osteras Olav, Reksen Olav, Reproductive Performance, Udder Health, and Antibiotic Resistance in Mastitis Bacteria isolated from Norwegian Red cows in Conventional and Organic Farming, 10.1186/1751-0147-52-11
  266. Gay, Bull Epid Santé Anim Alim, 53, 8 (2012)
  267. GEBREYES WONDWOSSEN A., THAKUR SIDDHARTHA, MORGAN MORROW W. E., Comparison of Prevalence, Antimicrobial Resistance, and Occurrence of Multidrug-Resistant Salmonella in Antimicrobial-Free and Conventional Pig Production, 10.4315/0362-028x-69.4.743
  268. Geenen P, Blaak H, Koene M, Havelaar A, van Leverstein‐Hall M, Mulders M, Neeling Ad, Roda Husman Ad, Stobberingh E and Wagenaar J, 2011. Antimicrobial resistance transmissible from food animals to humans–a risk profile. Available online:
  269. Geier M.S., Mikkelsen L.L., Torok V.A., Allison G.E., Olnood C.G., Boulianne M., Hughes R.J., Choct M., Comparison of alternatives to in-feed antimicrobials for the prevention of clinical necrotic enteritis : Necrotic enteritis in broilers, 10.1111/j.1365-2672.2010.04758.x
  270. Geldhof Marc F, Vanhee Merijn, Van Breedam Wander, Van Doorsselaere Jan, Karniychuk Uladzimir U, Nauwynck Hans J, Comparison of the efficacy of autogenous inactivated Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) vaccines with that of commercial vaccines against homologous and heterologous challenges, 10.1186/1746-6148-8-182
  271. Geli Patricia, Laxminarayan Ramanan, Dunne Michael, Smith David L., “One-Size-Fits-All”? Optimizing Treatment Duration for Bacterial Infections, 10.1371/journal.pone.0029838
  272. Gerzova Lenka, Babak Vladimir, Sedlar Karel, Faldynova Marcela, Videnska Petra, Cejkova Darina, Jensen Annette Nygaard, Denis Martine, Kerouanton Annaelle, Ricci Antonia, Cibin Veronica, Österberg Julia, Rychlik Ivan, Characterization of Antibiotic Resistance Gene Abundance and Microbiota Composition in Feces of Organic and Conventional Pigs from Four EU Countries, 10.1371/journal.pone.0132892
  273. Ghasemian M., Jahanian R., Dietary mannan-oligosaccharides supplementation could affect performance, immunocompetence, serum lipid metabolites, intestinal bacterial populations, and ileal nutrient digestibility in aged laying hens, 10.1016/j.anifeedsci.2015.12.012
  274. Giang Hoang Huong, Viet Tran Quoc, Ogle Brian, Lindberg Jan Erik, Growth performance, digestibility, gut environment and health status in weaned piglets fed a diet supplemented with potentially probiotic complexes of lactic acid bacteria, 10.1016/j.livsci.2010.01.010
  275. Gibbons J. F., Boland F., Buckley J. F., Butler F., Egan J., Fanning S., Markey B. K., Leonard F. C., Influences on antimicrobial prescribing behaviour of veterinary practitioners in cattle practice in Ireland, 10.1136/vr.100782
  276. Gisbert E., Skalli A., Campbell J., Solovyev M. M., Rodríguez C., Dias J., Polo J., Spray-dried plasma promotes growth, modulates the activity of antioxidant defenses, and enhances the immune status of gilthead sea bream ( ) fingerlings, 10.2527/jas.2014-7491
  277. Goff Debra A, Antimicrobial stewardship: bridging the gap between quality care and cost : , 10.1097/01.qco.0000393484.17894.05
  278. Goldbach Stine Gissel, Alban Lis, A cost–benefit analysis of Salmonella-control strategies in Danish pork production, 10.1016/j.prevetmed.2005.10.008
  279. Gonyou H.W., Hemsworth P.H., Barnett J.L., Effects of frequent interactions with humans on growing pigs, 10.1016/0168-1591(86)90119-x
  280. Gonyou H. W., Brumm M. C., Bush E., Deen J., Edwards S. A., Fangman T., McGlone J. J., Meunier-Salaun M., Morrison R. B., Spoolder H., Sundberg P. L., Johnson A. K., Application of broken-line analysis to assess floor space requirements of nursery and grower-finisher pigs expressed on an allometric basis, 10.2527/2006.841229x
  281. González-Martín J.V., Elvira L., Cerviño López M., Pérez Villalobos N., Calvo López-Guerrero E., Astiz S., Reducing antibiotic use: Selective metaphylaxis with florfenicol in commercial feedlots, 10.1016/j.livsci.2011.05.016
  282. GOOSSENS M. C., CATRY B., VERHAEGEN J., Antimicrobial resistance to benzylpenicillin in invasive pneumococcal disease in Belgium, 2003–2010: the effect of altering clinical breakpoints, 10.1017/s0950268812001057
  283. Gopalakannan Ayyaru, Arul Venkatesan, Immunomodulatory effects of dietary intake of chitin, chitosan and levamisole on the immune system of Cyprinus carpio and control of Aeromonas hydrophila infection in ponds, 10.1016/j.aquaculture.2006.01.012
  284. Grandin Temple, Animal Handling, 10.1016/s0749-0720(15)31155-5
  285. Grandin, Humane livestock handling, 227 (2008)
  286. Grant Ar’Quette, Hashem Fawzy, Parveen Salina, Salmonella and Campylobacter : Antimicrobial resistance and bacteriophage control in poultry, 10.1016/
  287. Grave K., Surveillance of the overall consumption of antibacterial drugs in humans, domestic animals and farmed fish in Norway in 1992 and 1996, 10.1093/jac/43.2.243
  288. Grave Kari, Jensen Vibeke Frøkjær, Odensvik Kristina, Wierup Martin, Bangen Marit, Usage of veterinary therapeutic antimicrobials in Denmark, Norway and Sweden following termination of antimicrobial growth promoter use, 10.1016/j.prevetmed.2006.02.003
  289. Grema Hafsat Ali, Methicillin Resistant Staphylococcus aureus (MRSA): A Review, 10.14737/journal.aavs/2015/
  290. Grinnell, Mmwr‐Morbidity and Mortality Weekly Report, 62, 553 (2013)
  291. Gross W. B., Siegel P. B., Why Some Get Sick, 10.1093/japr/6.4.453
  292. Guerra-Ordaz A. A., Gonzalez-Ortiz G., La Ragione R. M., Woodward M. J., Collins J. W., Perez J. F., Martin-Orue S. M., Lactulose and Lactobacillus plantarum, a Potential Complementary Synbiotic To Control Postweaning Colibacillosis in Piglets, 10.1128/aem.00770-14
  293. Gupta, The Official Scientific Journal of Delhi Ophthalmological Society, 25, 190 (2015)
  294. Guy J.H, Rowlinson P, Chadwick J.P, Ellis M, Health conditions of two genotypes of growing-finishing pig in three different housing systems: implications for welfare, 10.1016/s0301-6226(01)00327-x
  295. Guy Sarita Z. Y., Thomson Peter C., Hermesch Susanne, Selection of pigs for improved coping with health and environmental challenges: breeding for resistance or tolerance?, 10.3389/fgene.2012.00281
  296. Hajati H., Rezaei M., The Application of Prebiotics in Poultry Production, 10.3923/ijps.2010.298.304
  297. Halasa T., Østerås O., Hogeveen H., van Werven T., Nielen M., Meta-analysis of dry cow management for dairy cattle. Part 1. Protection against new intramammary infections, 10.3168/jds.2008-1740
  298. Halbert Lisa W., Kaneene John B., Ruegg Pamela L., Warnick Lorin D., Wells Scott J., Mansfield Linda S., Fossler Charles P., Campbell Amy M., Geiger-Zwald Angela M., Evaluation of antimicrobial susceptibility patterns inCampylobacterspp isolated from dairy cattle and farms managed organically and conventionally in the midwestern and northeastern United States, 10.2460/javma.228.7.1074
  299. Halbur, Journal of Clinical Microbiology, 38, 1156 (2000)
  300. Hammerum Anette M., Heuer Ole E., Emborg Hanne-Dorthe, Bagger-Skjøt Line, Jensen Vibeke F., Rogues Anne-Marie, Skov Robert L., Agersø Yvonne, Brandt Christian T., Seyfarth Anne Mette, Muller Arno, Hovgaard Karin, Ajufo Justin, Bager Flemming, Aarestrup Frank M., Frimodt-Møller Niels, Wegener Henrik C., Monnet Dominique L., Danish Integrated Antimicrobial Resistance Monitoring and Research Program, 10.3201/eid1311.070421
  301. Hammerum Anette M., Lester Camilla H., Heuer Ole E., Antimicrobial-Resistant Enterococci in Animals and Meat: A Human Health Hazard?, 10.1089/fpd.2010.0552
  302. Hammerum Anette M., Larsen Jesper, Andersen Vibe D., Lester Camilla H., Skovgaard Skytte Timmy S., Hansen Frank, Olsen Stefan S., Mordhorst Hanne, Skov Robert L., Aarestrup Frank M., Agersø Yvonne, Characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli obtained from Danish pigs, pig farmers and their families from farms with high or no consumption of third- or fourth-generation cephalosporins, 10.1093/jac/dku180
  303. Hampson David J., La Tom, Phillips Nyree D., Holyoake Patricia K., Brachyspira hyodysenteriae isolated from apparently healthy pig herds following an evaluation of a prototype commercial serological ELISA, 10.1016/j.vetmic.2016.05.016
  304. Han Jing, Wang Yang, Sahin Orhan, Shen Zhangqi, Guo Baoqing, Shen Jianzhong, Zhang Qijing, A Fluoroquinolone Resistance Associated Mutation in gyrA Affects DNA Supercoiling in Campylobacter jejuni, 10.3389/fcimb.2012.00021
  305. Hansson H, Lagerkvist CJ, Defining and measuring farmers' attitudes to farm animal welfare, 10.7120/09627286.23.1.047
  306. Hardeng F., Edge V.L., Mastitis, Ketosis, and Milk Fever in 31 Organic and 93 Conventional Norwegian Dairy Herds, 10.3168/jds.s0022-0302(01)74721-2
  307. Hasman H, Saputra D, Sicheritz‐Ponten T, Lund O, Svendsen CA, Frimodt‐Møller N and Aarestrup FM, 2013. Rapid whole genome sequencing for the detection and characterization of microorganisms directly from clinical samples. Journal of Clinical Microbiology, JCM, 02452‐02413.
  308. Hay K.E., Morton J.M., Clements A.C.A., Mahony T.J., Barnes T.S., Associations between feedlot management practices and bovine respiratory disease in Australian feedlot cattle, 10.1016/j.prevetmed.2016.03.017
  309. Health Council of the Netherlands , 2011. Antibiotics in food animal production and resistant bacteria in humans. Health Council of the Netherlands, The Hague, 2011; Publication no. 2011/16. Available online:
  310. Hedegaard Chris J., Heegaard Peter M.H., Passive immunisation, an old idea revisited: Basic principles and application to modern animal production systems, 10.1016/j.vetimm.2016.04.007
  311. Hedegaard Chris J., Strube Mikael L., Hansen Marie B., Lindved Bodil K., Lihme Allan, Boye Mette, Heegaard Peter M. H., Natural Pig Plasma Immunoglobulins Have Anti-Bacterial Effects: Potential for Use as Feed Supplement for Treatment of Intestinal Infections in Pigs, 10.1371/journal.pone.0147373
  312. Hedges Jodi F., Holderness Jeff, Jutila Mark A., Adjuvant materials that enhance bovine γδ T cell responses, 10.1016/j.vetimm.2016.03.010
  313. Heffernan Claire, Nielsen Louise, Thomson Kim, Gunn George, An exploration of the drivers to bio-security collective action among a sample of UK cattle and sheep farmers, 10.1016/j.prevetmed.2008.05.007
  314. Helms Morten, Vastrup Pernille, Gerner-Smidt Peter, Mølbak Kåre, Excess Mortality Associated with Antimicrobial Drug-ResistantSalmonellaTyphimurium, 10.3201/eid0805.010267
  315. Helms Morten, Simonsen Jacob, Mølbak Kåre, Quinolone Resistance Is Associated with Increased Risk of Invasive Illness or Death during Infection withSalmonellaSerotype Typhimurium, 10.1086/424570
  316. Hemsworth P.H., Barnett J.L., Hansen C., The influence of handling by humans on the behavior, growth, and corticosteroids in the juvenile female pig, 10.1016/0018-506x(81)90004-0
  317. Hemsworth P.H., Barnett J.L., Hansen C., The influence of handling by humans on the behaviour, reproduction and corticosteroids of male and female pigs, 10.1016/0168-1591(86)90123-1
  318. Hemsworth P H, Coleman G J, Barnett J L, Borg S, Relationships between human-animal interactions and productivity of commercial dairy cows., 10.2527/2000.78112821x
  319. Human-livestock interactions: The stockperson and the productivity and welfare of intensively farmed animals, ISBN:9781845936730, 10.1079/9781845936730.0000
  320. Hera, Developments in Biologicals, 117, 19 (2003)
  321. Hering Johanna, Hille Katja, Frömke Cornelia, von Münchhausen Christiane, Hartmann Maria, Schneider Bettina, Friese Anika, Roesler Uwe, Merle Roswitha, Kreienbrock Lothar, Prevalence and potential risk factors for the occurrence of cefotaxime resistant Escherichia coli in German fattening pig farms—A cross-sectional study, 10.1016/j.prevetmed.2014.06.014
  322. Hering Johanna, Frömke Cornelia, von Münchhausen Christiane, Hartmann Maria, Schneider Bettina, Friese Anika, Rösler Uwe, Kreienbrock Lothar, Hille Katja, Cefotaxime-resistant Escherichia coli in broiler farms—A cross-sectional investigation in Germany, 10.1016/j.prevetmed.2016.01.003
  323. Heringstad Bjørg, Klemetsdal Gunnar, Ruane John, Selection for mastitis resistance in dairy cattle: a review with focus on the situation in the Nordic countries, 10.1016/s0301-6226(99)00128-1
  324. Heuer O.E., Pedersen K., Andersen J.S., Madsen M., Prevalence and antimicrobial susceptibility of thermophilic Campylobacter in organic and conventional broiler flocks, 10.1046/j.1472-765x.2001.00994.x
  325. Heuer O.E., Pedersen K., Andersen J.S., Madsen M., Vancomycin-Resistant Enterococci (VRE) in Broiler Flocks 5 Years after the Avoparcin Ban, 10.1089/107662902760190680
  326. Heuer O.E., Pedersen K., Jensen L.B., Madsen M., Olsen J.E., Persistence of Vancomycin-Resistant Enterococci (VRE) in Broiler Houses after the Avoparcin Ban, 10.1089/10766290260469624
  327. Hiki Mototaka, Kawanishi Michiko, Abo Hitoshi, Kojima Akemi, Koike Ryoji, Hamamoto Shuichi, Asai Tetsuo, Decreased Resistance to Broad-Spectrum Cephalosporin inEscherichia colifrom Healthy Broilers at Farms in Japan After Voluntary Withdrawal of Ceftiofur, 10.1089/fpd.2015.1960
  328. Hill Colin, Guarner Francisco, Reid Gregor, Gibson Glenn R., Merenstein Daniel J., Pot Bruno, Morelli Lorenzo, Canani Roberto Berni, Flint Harry J., Salminen Seppo, Calder Philip C., Sanders Mary Ellen, Expert consensus document: The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic, 10.1038/nrgastro.2014.66
  329. Hinchliffe Steve, Ward Kim J., Geographies of folded life: How immunity reframes biosecurity, 10.1016/j.geoforum.2014.03.002
  330. HM Government , 2014. UK 5 year antimicrobial resistance (AMR) strategy 2013 to 2018: annual progress report and implementation plan 2014.
  331. Hodin Richard, Maintaining gut homeostasis: The butyrate–NF-κB connection, 10.1016/s0016-5085(00)70150-8
  332. Hofacre C. L., Froyman R., Gautrias B., George B., Goodwin M. A., Brown J., Use of Aviguard and Other Intestinal Bioproducts in Experimental Clostridium perfringens-Associated Necrotizing Enteritis in Broiler Chickens, 10.2307/1592685
  333. Hofacre C. L., Froyman R., George B., Goodwin M. A., Brown J., Use of Aviguard, Virginiamycin, or Bacitracin MD Against Clostridium perfringens-Associated Necrotizing Enteritis, 10.1093/japr/7.4.412
  334. Hofacre Charles L., Johnson Alison C., Kelly Barry J., Froyman Robrecht, Effect of a Commercial Competitive Exclusion Culture on Reduction of Colonization of an Antibiotic-Resistant Pathogenic Escherichia coli in Day-Old Broiler Chickens, 10.1637/0005-2086(2002)046[0198:eoacce];2
  335. Hogeveen H., Dykhuizen A.A., Sol J., Short- and long-term effects of a 2 year dairy herd health and management program, 10.1016/0167-5877(92)90035-e
  336. Hojberg O., Canibe N., Poulsen H. D., Hedemann M. S., Jensen B. B., Influence of Dietary Zinc Oxide and Copper Sulfate on the Gastrointestinal Ecosystem in Newly Weaned Piglets, 10.1128/aem.71.5.2267-2277.2005
  337. Hollis Aidan, Ahmed Ziana, Preserving Antibiotics, Rationally, 10.1056/nejmp1311479
  338. Holman Devin B., Chénier Martin R., Antimicrobial use in swine production and its effect on the swine gut microbiota and antimicrobial resistance, 10.1139/cjm-2015-0239
  339. Hong Young-Ho, Kwon Ji-Seon, Lee Hyun-Jeong, Song Chang-Seon, Lee Sang-Won, Eradication ofMycoplasma synoviaefrom a multi-age broiler breeder farm using antibiotics therapy, 10.3382/ps/pev232
  340. Hoseinifar Seyed Hossein, Esteban Maria Ángeles, Cuesta Alberto, Sun Yun-Zhang, Prebiotics and Fish Immune Response: A Review of Current Knowledge and Future Perspectives, 10.1080/23308249.2015.1052365
  341. Hoseinifar Seyed Hossein, Mirvaghefi Alireza, Amoozegar Mohammad Ali, Sharifian Maryam, Esteban M. Ángeles, Modulation of innate immune response, mucosal parameters and disease resistance in rainbow trout (Oncorhynchus mykiss) upon synbiotic feeding, 10.1016/j.fsi.2015.03.029
  342. Hossain M. M., Begum M., Nyachoti C. M., Hancock J. D., Kim I. H., Dietary fenugreek seed extract improves performance and reduces fecal E. coli counts and fecal gas emission in lactating sows and suckling piglets, 10.4141/cjas-2014-154
  343. Houe H, Uttenthal A, Pedersen K, Jensen AM and Bartlett P, 1996. Risk factors for a change in bovine virus diarrhoea seropositivity in 41 Danish dairy herds during two years. Proceedings of the 3. ESVV Symposium on Pestvirus Infections.
  344. Houe H., Lindberg A., Moennig V., Test Strategies in Bovine Viral Diarrhea Virus Control and Eradication Campaigns in Europe, 10.1177/104063870601800501
  345. Houe, Control and eradication of endemic infectious diseases in cattle (2014)
  346. Hovi M and Roderick S, 2000. Mastitis in organic dairy herds in England and Wales. Proc. Br. Mast. Conf. Axient Information Services, Crewe, UK. 86 pp.
  347. Hovi M, Sundrum A, Thamsborg S.M, Animal health and welfare in organic livestock production in Europe: current state and future challenges, 10.1016/s0301-6226(02)00320-2
  348. Hrabák Jaroslav, Walková Radka, Študentová Vendula, Chudáčková Eva, Bergerová Tamara, Carbapenemase Activity Detection by Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry, 10.1128/jcm.00984-11
  349. HS (Hushållningssällskapet), 2010. Slaktkropparnas kvalitet i ekologisk uppfödning 2010 (Carcass quality in organic production 2010, in Swedish). Hushållningssällskapet, HS Consult, Uppsala, Sweden, pp. 43. Available online:
  350. Huang Eileen, Gurzau Anca E., Hanson Blake M., Kates Ashley E., Smith Tara C., Pettigrew Melinda M., Spinu Marina, Rabinowitz Peter M., Detection of livestock-associated methicillin-resistant Staphylococcus aureus among swine workers in Romania, 10.1016/j.jiph.2014.03.008
  351. Huff W. E., Huff G. R., Rath N. C., Balog J. M., Donoghue A. M., Alternatives to antibiotics: utilization of bacteriophage to treat colibacillosis and prevent foodborne pathogens, 10.1093/ps/84.4.655
  352. Huff G. R., Huff W. E., Rath N. C., Solis de los Santos F., Farnell M. B., Donoghue A. M., Influence of Hen Age on the Response of Turkey Poults to Cold Stress, Escherichia coli Challenge, and Treatment with a Yeast Extract Antibiotic Alternative, 10.1093/ps/86.4.636
  353. Hughes L., Hermans P., Morgan K., Risk factors for the use of prescription antibiotics on UK broiler farms, 10.1093/jac/dkn017
  354. Huijbers Patricia M.C., van Hoek Angela H.A.M., Graat Elisabeth A.M., Haenen Anja P.J., Florijn Alice, Hengeveld Paul D., van Duijkeren Engeline, Methicillin-resistant Staphylococcus aureus and extended-spectrum and AmpC β-lactamase-producing Escherichia coli in broilers and in people living and/or working on organic broiler farms, 10.1016/j.vetmic.2014.12.010
  355. Hume M. E., Historic perspective: Prebiotics, probiotics, and other alternatives to antibiotics, 10.3382/ps.2010-01030
  356. Huxley J.N., Green M.J., Green L.E., Bradley A.J., Evaluation of the Efficacy of an Internal Teat Sealer During the Dry Period, 10.3168/jds.s0022-0302(02)74108-8
  357. Huxley, Asian Journal of Bio Science, 6, 33 (2011)
  358. Huynh T.T.T., Aarnink A.J.A., Gerrits W.J.J., Heetkamp M.J.H., Canh T.T., Spoolder H.A.M., Kemp B., Verstegen M.W.A., Thermal behaviour of growing pigs in response to high temperature and humidity, 10.1016/j.applanim.2004.10.020
  359. Imbeault Sandra, Parent Serge, Lagacé Michel, Uhland Carl F., Blais Jean-François, Using Bacteriophages to Prevent Furunculosis Caused byAeromonas salmonicidain Farmed Brook Trout, 10.1577/h06-019.1
  360. Ives, Veterinary Clinics of North America: Food Animal Practice, 31, 341 (2015)
  361. Jansen J., van den Borne B.H.P., Renes R.J., van Schaik G., Lam T.J.G.M., Leeuwis C., Explaining mastitis incidence in Dutch dairy farming: The influence of farmers’ attitudes and behaviour, 10.1016/j.prevetmed.2009.08.015
  362. Jensen V.F., Jacobsen E., Bager F., Veterinary antimicrobial-usage statistics based on standardized measures of dosage, 10.1016/j.prevetmed.2004.04.001
  363. Jensen V. F., Does the use of antibiotics in food animals pose a risk to human health? An unbiased review?, 10.1093/jac/dkh264
  364. Jensen US, Muller A, Brandt CT, Frimodt‐Møller N, Hammerum AM, Monnet DL and Group DS, 2010. Effect of generics on price and consumption of ciprofloxacin in primary healthcare: the relationship to increasing resistance. Journal of Antimicrobial Chemotherapy, dkq093.
  365. Jensen A. N., Hansen L. L., Baggesen D. L., Mølbak L., Effects of feeding finisher pigs with chicory or lupine feed for one week or two weeks before slaughter with respect to levels of Bifidobacteria and Campylobacter, 10.1017/s175173111200119x
  366. Jensen K.H., Damgaard B.M., Andresen L.O., Jørgensen E., Carstensen L., Prevention of post weaning diarrhoea by a Saccharomyces cerevisiae-derived product based on whole yeast, 10.1016/j.anifeedsci.2013.03.004
  367. Jensen V.F., de Knegt L.V., Andersen V.D., Wingstrand A., Temporal relationship between decrease in antimicrobial prescription for Danish pigs and the “Yellow Card” legal intervention directed at reduction of antimicrobial use, 10.1016/j.prevetmed.2014.08.006
  368. Jensen V.F., Sommer H.M., Struve T., Clausen J., Chriél M., Factors associated with usage of antimicrobials in commercial mink (Neovison vison) production in Denmark, 10.1016/j.prevetmed.2016.01.023
  369. Jha Rajesh, Berrocoso Julio F.D., Dietary fiber and protein fermentation in the intestine of swine and their interactive effects on gut health and on the environment: A review, 10.1016/j.anifeedsci.2015.12.002
  370. Jiang Y. W., Sims M. D., Conway D. P., The efficacy of TAMUS 2032 in preventing a natural outbreak of colibacillosis in broiler chickens in floor pens, 10.1093/ps/84.12.1857
  371. Johansson Åsa, Sóki József, Nagy Elisabeth, Instant screening and verification of carbapenemase activity in Bacteroides fragilis in positive blood culture, using matrix-assisted laser desorption ionization–time of flight mass spectrometry, 10.1099/jmm.0.075465-0
  372. Jones R. Bryan, The tonic immobility reaction of the domestic fowl: a review, 10.1079/wps19860008
  373. Jones P.J., Marier E.A., Tranter R.B., Wu G., Watson E., Teale C.J., Factors affecting dairy farmers’ attitudes towards antimicrobial medicine usage in cattle in England and Wales, 10.1016/j.prevetmed.2015.05.010
  374. Jourdain Béatrice, Joly-Guillou Marie-Laure, Dombret Marie-Christine, Calvat Sylvie, Trouillet Jean-Louis, Gibert Claude, Chastre Jean, Usefulness of Quantitative Cultures of BAL Fluid for Diagnosing Nosocomial Pneumonia in Ventilated Patients, 10.1378/chest.111.2.411
  375. Józefiak D., Sip A., Kaczmarek S., Rutkowski A., The effects of Carnobacterium divergens AS7 bacteriocin on gastrointestinal microflora in vitro and on nutrient retention in broiler chickens, 10.22358/jafs/66310/2010
  376. Jozefiak D., Sip A., Rutkowski A., Rawski M., Kaczmarek S., Wolun-Cholewa M., Engberg R. M., Hojberg O., Lyophilized Carnobacterium divergens AS7 bacteriocin preparation improves performance of broiler chickens challenged with Clostridium perfringens, 10.3382/ps.2012-02151
  377. Józefiak Damian, Kierończyk Bartosz, Juśkiewicz Jerzy, Zduńczyk Zenon, Rawski Mateusz, Długosz Jakub, Sip Anna, Højberg Ole, Dietary Nisin Modulates the Gastrointestinal Microbial Ecology and Enhances Growth Performance of the Broiler Chickens, 10.1371/journal.pone.0085347
  378. Jung J. S., Eberl T., Sparbier K., Lange C., Kostrzewa M., Schubert S., Wieser A., Rapid detection of antibiotic resistance based on mass spectrometry and stable isotopes, 10.1007/s10096-013-2031-5
  379. Jung Kwonil, Saif Linda J., Porcine epidemic diarrhea virus infection: Etiology, epidemiology, pathogenesis and immunoprophylaxis, 10.1016/j.tvjl.2015.02.017
  380. Jurado-Gámez Henry, Ramírez T Cristina, Martínez B Javier, Evaluación in vivo de Lactobacillus plantarum como alternativa al uso de antibióticos en lechones, 10.21897/rmvz.131
  381. Kadouri Daniel E., To Kevin, Shanks Robert M. Q., Doi Yohei, Predatory Bacteria: A Potential Ally against Multidrug-Resistant Gram-Negative Pathogens, 10.1371/journal.pone.0063397
  382. Kadzere C.T, Murphy M.R, Silanikove N, Maltz E, Heat stress in lactating dairy cows: a review, 10.1016/s0301-6226(01)00330-x
  383. Kaldhusdal M., Schneitz C., Hofshagen M., Skjerve E., Reduced Incidence of Clostridium perfringens-Associated Lesions and Improved Performance in Broiler Chickens Treated with Normal Intestinal Bacteria from Adult Fowl, 10.2307/1593022
  384. Kang Kyung-Il, El-Gazzar Mohamed, Sellers Holly S., Dorea Fernanda, Williams Susan M., Kim Taejoong, Collett Stephen, Mundt Egbert, Investigation into the aetiology of runting and stunting syndrome in chickens, 10.1080/03079457.2011.632402
  385. Kapareiko Diane, Lim Hyun Jeong, Schott Eric J., Hanif Ammar, Wikfors Gary H., Isolation and Evaluation of New Probiotic Bacteria for use in Shellfish Hatcheries: II. Effects of aVibriosp. Probiotic Candidate Upon Survival of Oyster Larvae (Crassostrea virginica) in Pilot-Scale Trials, 10.2983/035.030.0304
  386. Grandin, Animal Welfare: A Practical Approach, 267 (2015)
  387. Karunasagar I, 2012. Alternatives to antibiotics in aquaculture. Improving biosecurity through prudent and responsible use of veterinary medicines in aquatic food production, 155.
  388. Kassem II, Kehinde O, Kumar A and Rajashekara G, 2016. Antimicrobial‐resistant campylobacter in organically and conventionally raised layer chickens. Foodborne Pathogens and Disease, online ahead of print.
  389. Kehoe S.I., Carlson D.B., Influence of nonmedicated additives as alternatives to antibiotics on calf growth and health, 10.15232/pas.2015-01416
  390. Kelley, Annals of Veterinary Research, 11, 445 (1980)
  391. Kemmett K., Williams N. J., Chaloner G., Humphrey S., Wigley P., Humphrey T., The contribution of systemicEscherichia coliinfection to the early mortalities of commercial broiler chickens, 10.1080/03079457.2013.866213
  392. Kerr Ashley K., Farrar Ashley M., Waddell Lisa A., Wilkins Wendy, Wilhelm Barbara J., Bucher Oliver, Wills Robert W., Bailey R. Hart, Varga Csaba, McEwen Scott A., Rajić Andrijana, A systematic review-meta-analysis and meta-regression on the effect of selected competitive exclusion products on Salmonella spp. prevalence and concentration in broiler chickens, 10.1016/j.prevetmed.2013.04.005
  393. Khadem Alireza, Soler Laura, Everaert Nadia, Niewold Theo A., Growth promotion in broilers by both oxytetracycline and Macleaya cordata extract is based on their anti-inflammatory properties, 10.1017/s0007114514001871
  394. Khairnar Krishna, Raut Mahendra P, Chandekar Rajshree H, Sanmukh Swapnil G, Paunikar Waman N, Novel bacteriophage therapy for controlling metallo-beta-lactamase producing Pseudomonas aeruginosa infection in Catfish, 10.1186/1746-6148-9-264
  395. Khan Sohail Hassan, Iqbal Javid, Recent advances in the role of organic acids in poultry nutrition, 10.1080/09712119.2015.1079527
  396. Khmylov, Svinovodstvo (Moskva), 2, 53 (2015)
  397. Kim Min-Kook, Lee Hong-Gu, Park Jeong-Ah, Kang Sang-Kee, Choi Yun-Jaie, Effect of Feeding Direct-fed Microbial as an Alternative to Antibiotics for the Prophylaxis of Calf Diarrhea in Holstein Calves, 10.5713/ajas.2011.10322
  398. King, Journal of the American Veterinary Medical Association, 127, 320 (1955)
  399. KLARE I., HEIER H., CLAUS H., BÖHME G., MARIN S., SELTMANN G., HAKENBECK R., ANTANASSOVA V., WITTE W., Enterococcus faeciumStrains withvanA-Mediated High-Level Glycopeptide Resistance Isolated from Animal Foodstuffs and Fecal Samples of Humans in the Community, 10.1089/mdr.1995.1.265
  400. Koblentz Gregory D., Biosecurity Reconsidered: Calibrating Biological Threats and Responses, 10.1162/isec.2010.34.4.96
  401. Koeck A., Egger-Danner C., Fuerst C., Obritzhauser W., Fuerst-Waltl B., Genetic analysis of reproductive disorders and their relationship to fertility and milk yield in Austrian Fleckvieh dual-purpose cows, 10.3168/jds.2009-2570
  402. Koeck A., Miglior F., Kelton D.F., Schenkel F.S., Health recording in Canadian Holsteins: Data and genetic parameters, 10.3168/jds.2011-5127
  403. Kogut M. H., Genovese K. J., He H., Swaggerty C. L., Jiang Y., Modulation of Chicken Intestinal Immune Gene Expression by Small Cationic Peptides as Feed Additives during the First Week Posthatch, 10.1128/cvi.00322-13
  404. Kohanski Michael A., DePristo Mark A., Collins James J., Sublethal Antibiotic Treatment Leads to Multidrug Resistance via Radical-Induced Mutagenesis, 10.1016/j.molcel.2010.01.003
  405. Kohlert Claudia, Schindler Gernot, März Reinhard W, Abel Gudrun, Brinkhaus Benno, Derendorf Hartmut, Gräfe Eva-Ulrike, Veit Markus, Systemic Availability and Pharmacokinetics of Thymol in Humans, 10.1177/009127002401102678
  406. Kola A., Kohler C., Pfeifer Y., Schwab F., Kuhn K., Schulz K., Balau V., Breitbach K., Bast A., Witte W., Gastmeier P., Steinmetz I., High prevalence of extended-spectrum- -lactamase-producing Enterobacteriaceae in organic and conventional retail chicken meat, Germany, 10.1093/jac/dks295
  407. Kolstoe E. M., Iversen T., Østensvik Ø., Abdelghani A., Secic I., Nesbakken T., Specific Pathogen-Free Pig Herds also Free fromCampylobacter?, 10.1111/zph.12132
  408. Komalova, Svinovodstvo (Moskva), 1, 9 (2013)
  409. Kommera S. K., Mateo R. D., Neher F. J., Kim S. W., Phytobiotics and Organic Acids As Potential Alternatives to the Use of Antibiotics in Nursery Pig Diets, 10.5713/ajas.2006.1784
  410. Köser Claudio U., Ellington Matthew J., Peacock Sharon J., Whole-genome sequencing to control antimicrobial resistance, 10.1016/j.tig.2014.07.003
  411. Kozdruń Wojciech, Czekaj Hanna, Styś Natalia, Avian zoonoses – a review, 10.1515/bvip-2015-0026
  412. Krause D. O., Bhandari S. K., House J. D., Nyachoti C. M., Response of Nursery Pigs to a Synbiotic Preparation of Starch and an Anti-Escherichia coli K88 Probiotic, 10.1128/aem.01427-10
  413. Krieter, DTW. Deutsche Tierarztliche Wochenschrift, 111, 462 (2004)
  414. Kristensen Charlotte S, Vinther Jens, Svensmark Birgitta, Bækbo Poul, A field evaluation of two vaccines against Mycoplasma hyopneumoniae infection in pigs, 10.1186/1751-0147-56-24
  415. Kritas S. K., Morrison R. B., Evaluation of probiotics as a substitute for antibiotics in a large pig nursery, 10.1136/vr.156.14.447
  416. Krogh M.A., Enevoldsen C., Evaluation of effects of metritis management in a complex dairy herd health management program, 10.3168/jds.2012-5580
  417. Kruse AB, Johansen C, Alban L and Nielsen LR, 2016. Evaluation of biosecurity in 140 Danish pig herds using Biocheck. ugent®. Proceedings of the SVEPM2016.
  418. Kuipers A., Koops W.J., Wemmenhove H., Antibiotic use in dairy herds in the Netherlands from 2005 to 2012, 10.3168/jds.2014-8428
  419. La Ragione R, Competitive exclusion by Bacillus subtilis spores of Salmonella enterica serotype Enteritidis and Clostridium perfringens in young chickens, 10.1016/s0378-1135(03)00077-4
  420. Laanen M., Persoons D., Ribbens S., de Jong E., Callens B., Strubbe M., Maes D., Dewulf J., Relationship between biosecurity and production/antimicrobial treatment characteristics in pig herds, 10.1016/j.tvjl.2013.08.029
  421. Lacasta D., Ferrer L.M., Ramos J.J., González J.M., Ortín A., Fthenakis G.C., Vaccination schedules in small ruminant farms, 10.1016/j.vetmic.2015.07.018
  422. Lallès Jean-Paul, Bosi Paolo, Smidt Hauke, Stokes Chris R., Weaning — A challenge to gut physiologists, 10.1016/j.livsci.2007.01.091
  423. Lam TJGM, Wessels RJ and Jansen J, 2016. RESET the mindset of antibiotic usage in dairy cows. Proceedings of the World Buiatrics Congress, Dublin, Ireland, 3–8 July 2016, 82–84.
  424. Landers Timothy F., Cohen Bevin, Wittum Thomas E., Larson Elaine L., A Review of Antibiotic Use in Food Animals: Perspective, Policy, and Potential, 10.1177/003335491212700103
  425. Landin Håkan, Mörk Marie Jansson, Larsson Maria, Waller Karin Persson, Vaccination against Staphylococcus aureus mastitis in two Swedish dairy herds, 10.1186/s13028-015-0171-6
  426. Lange C., Schubert S., Jung J., Kostrzewa M., Sparbier K., Quantitative Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Rapid Resistance Detection, 10.1128/jcm.01872-14
  427. Lara Lucas, Rostagno Marcos, Impact of Heat Stress on Poultry Production, 10.3390/ani3020356
  428. Larsen Inge, Nielsen Søren Saxmose, Olsen John Elmerdahl, Nielsen Jens Peter, The efficacy of oxytetracycline treatment at batch, pen and individual level on Lawsonia intracellularis infection in nursery pigs in a randomised clinical trial, 10.1016/j.prevetmed.2015.12.018
  429. Laureyns Jozef, Ribbens Stefaan, de Kruif Aart, Control of bovine virus diarrhoea at the herd level: Reducing the risk of false negatives in the detection of persistently infected cattle, 10.1016/j.tvjl.2008.11.014
  430. Lava M., Pardon B., Schüpbach-Regula G., Keckeis K., Deprez P., Steiner A., Meylan M., Effect of calf purchase and other herd-level risk factors on mortality, unwanted early slaughter, and use of antimicrobial group treatments in Swiss veal calf operations, 10.1016/j.prevetmed.2016.01.020
  431. Lava M., Schüpbach-Regula G., Steiner A., Meylan M., Antimicrobial drug use and risk factors associated with treatment incidence and mortality in Swiss veal calves reared under improved welfare conditions, 10.1016/j.prevetmed.2016.02.002
  432. Lazarus B., Paterson D. L., Mollinger J. L., Rogers B. A., Do Human Extraintestinal Escherichia coli Infections Resistant to Expanded-Spectrum Cephalosporins Originate From Food-Producing Animals? A Systematic Review, 10.1093/cid/ciu785
  433. Lee S.-K., Chon J.-W., Song K.-Y., Hyeon J.-Y., Moon J.-S., Seo K.-H., Prevalence, characterization, and antimicrobial susceptibility of Salmonella Gallinarum isolated from eggs produced in conventional or organic farms in South Korea, 10.3382/ps.2013-03175
  434. Lee Y. K., Katya K., Yun H. H., Yoon M.Y., Park J. K., Sung J. S., Shin H. S., Bai S.C., Evaluation of dietary yellow loess as an antibiotic replacer on growth, immune responses, serological characteristics and disease resistance in rainbow trout,Oncorhynchus mykiss, 10.1111/anu.12348
  435. Leekitcharoenphon Pimlapas, Raufu Ibrahim, Nielsen Mette T., Rosenqvist Lund Birthe S., Ameh James A., Ambali Abdul G., Sørensen Gitte, Le Hello Simon, Aarestrup Frank M., Hendriksen Rene S., Investigating Salmonella Eko from Various Sources in Nigeria by Whole Genome Sequencing to Identify the Source of Human Infections, 10.1371/journal.pone.0156212
  436. Lees Peter, Shojaee Aliabadi Fariborz, Rational dosing of antimicrobial drugs: animals versus humans, 10.1016/s0924-8579(02)00025-0
  437. LeJeune J. T., Kauffman M. D., Effect of Sand and Sawdust Bedding Materials on the Fecal Prevalence of Escherichia coli O157:H7 in Dairy Cows, 10.1128/aem.71.1.326-330.2005
  438. LESTARI SHOFIYAH IKA, HAN FEIFEI, WANG FEI, GE BEILEI, Prevalence and Antimicrobial Resistance of Salmonella Serovars in Conventional and Organic Chickens from Louisiana Retail Stores, 10.4315/0362-028x-72.6.1165
  439. Levy Sharon, Reduced Antibiotic Use in Livestock: How Denmark Tackled Resistance, 10.1289/ehp.122-a160
  440. Li B. T., Van Kessel A. G., Caine W. R., Huang S. X., Kirkwood R. N., Small intestinal morphology and bacterial populations in ileal digesta and feces of newly weaned pigs receiving a high dietary level of zinc oxide, 10.4141/a01-043
  441. Li Hao, Ma Man-Li, Xie Hui-Jun, Kong Jian, Biosafety evaluation of bacteriophages for treatment of diarrhea due to intestinal pathogen Escherichia coli 3-2 infection of chickens, 10.1007/s11274-011-0784-5
  442. Li Xiaoyu, Wang Lili, Zhen Yuhong, Li Shuying, Xu Yongping, Chicken egg yolk antibodies (IgY) as non-antibiotic production enhancers for use in swine production: a review, 10.1186/s40104-015-0038-8
  443. Liakopoulos Apostolos, Geurts Yvon, Dierikx Cindy M., Brouwer Michael S.M., Kant Arie, Wit Ben, Heymans Raymond, van Pelt Wilfrid, Mevius Dik J., Extended-Spectrum Cephalosporin-ResistantSalmonella entericaserovar Heidelberg Strains, the Netherlands1, 10.3201/eid2207.151377
  444. Lin Jun, Antibiotic growth promoters enhance animal production by targeting intestinal bile salt hydrolase and its producers, 10.3389/fmicb.2014.00033
  445. Lindberg Ann L.E, Alenius Stefan, Principles for eradication of bovine viral diarrhoea virus (BVDV) infections in cattle populations, 10.1016/s0378-1135(98)00270-3
  446. Lindberg Jan, Fiber effects in nutrition and gut health in pigs, 10.1186/2049-1891-5-15
  447. Liu, PloS One, 9, 1 (2014)
  448. Liu Yi-Yun, Wang Yang, Walsh Timothy R, Yi Ling-Xian, Zhang Rong, Spencer James, Doi Yohei, Tian Guobao, Dong Baolei, Huang Xianhui, Yu Lin-Feng, Gu Danxia, Ren Hongwei, Chen Xiaojie, Lv Luchao, He Dandan, Zhou Hongwei, Liang Zisen, Liu Jian-Hua, Shen Jianzhong, Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study, 10.1016/s1473-3099(15)00424-7
  449. Liu C‐Y, Han Y‐Y, Shih P‐H, Lian W‐N, Wang H‐H, Lin C‐H, Hsueh P‐R, Wang J‐K and Wang Y‐L, 2016. Rapid bacterial antibiotic susceptibility test based on simple surface‐enhanced Raman spectroscopic biomarkers. Scientific Reports, 6.
  451. Loh Teck, Choe Di, Foo Hooi, Sazili Awis, Bejo Mohd, Effects of feeding different postbiotic metabolite combinations produced by Lactobacillus plantarum strains on egg quality and production performance, faecal parameters and plasma cholesterol in laying hens, 10.1186/1746-6148-10-149
  452. Looft T., Johnson T. A., Allen H. K., Bayles D. O., Alt D. P., Stedtfeld R. D., Sul W. J., Stedtfeld T. M., Chai B., Cole J. R., Hashsham S. A., Tiedje J. M., Stanton T. B., In-feed antibiotic effects on the swine intestinal microbiome, 10.1073/pnas.1120238109
  453. Lorenz, Irish Veterinary Journal, 64, 1 (2011)
  454. Lough G, Kyriazakis I, Bergmann S, Lengeling A and Doeschl‐Wilson AB, 2015. Health trajectories reveal the dynamic contributions of host genetic resistance and tolerance to infection outcome. Proceedings of the Royal Society B: Biological Sciences B, 20152151.
  455. Lovaas B, 2006. BVD in the Feedlot, Part I. Extension, University of Minnesota. Available online:
  456. Luangtongkum T., Morishita T. Y., Ison A. J., Huang S., McDermott P. F., Zhang Q., Effect of Conventional and Organic Production Practices on the Prevalence and Antimicrobial Resistance of Campylobacter spp. in Poultry, 10.1128/aem.72.5.3600-3607.2006
  457. Lückstädt, Int Aquafeed, 9, 21 (2006)
  458. Yániz Jesús Luis, Marco-Aguado María Angeles, Mateos José Angel, Santolaria Pilar, Bacterial contamination of ram semen, antibiotic sensitivities, and effects on sperm quality during storage at 15°C, 10.1016/j.anireprosci.2010.08.006
  459. Lund Vonne, Natural living—a precondition for animal welfare in organic farming, 10.1016/j.livprodsci.2005.08.005
  460. Lund M, Hougaard JL, Biira J and Houe H (University of Copenhagen), 2012. Economic incentives for disease prevention in Danish pig and cattle herds. 70.
  461. M'Sadeq Shawkat A., Wu Shubiao, Swick Robert A., Choct Mingan, Towards the control of necrotic enteritis in broiler chickens with in-feed antibiotics phasing-out worldwide, 10.1016/j.aninu.2015.02.004
  462. Ma Li, Gao Yongjun, Maresso Anthony W., Escherichia coli Free Radical-Based Killing Mechanism Driven by a Unique Combination of Iron Restriction and Certain Antibiotics, 10.1128/jb.00758-15
  463. MacInnes, Canadian Journal of Veterinary Research‐Revue Canadienne De Recherche Veterinaire, 63, 83 (1999)
  464. Maciuca IE, Williams NJ, Tuchilus C, Dorneanu O, Guguianu E, Carp‐Carare C, Rimbu C and Timofte D, 2015. High Prevalence OF Escherichia coli‐producing CTX‐M‐15 extended‐spectrum beta‐lactamases in poultry and human clinical isolates in Romania. Microbial Drug Resistance.
  465. Mack L. A., Felver-Gant J. N., Dennis R. L., Cheng H. W., Genetic variations alter production and behavioral responses following heat stress in 2 strains of laying hens, 10.3382/ps.2012-02589
  466. Madec F, Bridoux N, Bounaix S, Jestin A, Measurement of digestive disorders in the piglet at weaning and related risk factors, 10.1016/s0167-5877(97)00057-3
  467. Maes Dominiek, Deluyker Hubert, Verdonck Marc, Castryck Frans, Miry Cora, Vrijens Bernard, de Kruif Aart, Herd factors associated with the seroprevalences of four major respiratory pathogens in slaughter pigs from farrow-to-finish pig herds, 10.1051/vetres:2000122
  468. Maes D., Segales J., Meyns T., Sibila M., Pieters M., Haesebrouck F., Control of Mycoplasma hyopneumoniae infections in pigs, 10.1016/j.vetmic.2007.09.008
  469. Maillard Jean-Yves, Bloomfield Sally, Coelho Joana Rosado, Collier Phillip, Cookson Barry, Fanning Séamus, Hill Andrew, Hartemann Philippe, Mcbain Andrew J., Oggioni Marco, Sattar Syed, Schweizer Herbert P., Threlfall John, Does Microbicide Use in Consumer Products Promote Antimicrobial Resistance? A Critical Review and Recommendations for a Cohesive Approach to Risk Assessment, 10.1089/mdr.2013.0039
  470. Makoschey, International Dairy Topics, 6, 13 (2007)
  471. Mallard, Japanese Journal of Veterinary Research, 63, S37 (2015)
  472. Mankad Aditi, Psychological influences on biosecurity control and farmer decision-making. A review, 10.1007/s13593-016-0375-9
  473. Mapara Nikunj, Sharma Mansi, Shriram Varsha, Bharadwaj Renu, Mohite K. C., Kumar Vinay, Antimicrobial potentials of Helicteres isora silver nanoparticles against extensively drug-resistant (XDR) clinical isolates of Pseudomonas aeruginosa, 10.1007/s00253-015-6938-x
  474. MARAN , 2011. MARAN‐2009 ‐ Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands In 2009. Available online:
  475. MARAN , 2012. MARAN‐2012 ‐ Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands in 2010/2011. Available online:
  476. MARAN , 2015. MARAN‐2015 ‐ Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands in 2014. Available online:
  477. MARAN , 2016. MARAN‐2016 ‐ Monitoring of Antimicrobial Resistance and Antibiotic Usage in Animals in the Netherlands in 2015. Available online:
  478. Mariadason, American Journal of Physiology, 272, G705 (1997)
  479. Mariner J. C., House J. A., Mebus C. A., Sollod A. E., Chibeu D., Jones B. A., Roeder P. L., Admassu B., van 't Klooster G. G. M., Rinderpest Eradication: Appropriate Technology and Social Innovations, 10.1126/science.1223805
  480. Marquetoux Nelly, Stevenson Mark A., Wilson Peter, Ridler Anne, Heuer Cord, Using social network analysis to inform disease control interventions, 10.1016/j.prevetmed.2016.01.022
  481. Martin L, Andreassi E, Watson W and Coon C, 2011. Stress and animal health: physiological mechanisms and ecological consequences. Nature Education Knowledge, 3.
  482. Martinez Andres W., Phillips Scott T., Whitesides George M., Carrilho Emanuel, Diagnostics for the Developing World: Microfluidic Paper-Based Analytical Devices, 10.1021/ac9013989
  483. Martinez M. N., Papich M. G., Drusano G. L., Dosing Regimen Matters: the Importance of Early Intervention and Rapid Attainment of the Pharmacokinetic/Pharmacodynamic Target, 10.1128/aac.05360-11
  484. Martiny Delphine, Visscher Alain, Catry Boudewijn, Chatellier Sonia, Vandenberg Olivier, Optimization of Campylobacter growth conditions for further identification by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS), 10.1016/j.mimet.2013.06.018
  485. McAloon Conor G., Whyte Paul, More Simon J., O’Grady Luke, Doherty Michael L., Development of a HACCP-based approach to control paratuberculosis in infected Irish dairy herds, 10.1016/j.prevetmed.2015.04.018
  486. McCapes R. H., Yamamoto R., Ortmayer H. B., Scott W. F., Injecting Antibiotics into Turkey Hatching Eggs to Eliminate Mycoplasma meleagridis Infection, 10.2307/1589076
  487. McDermott J.J., Schukken Y.H., A review of methods used to adjust for cluster effects in explanatory epidemiological studies of animal populations, 10.1016/0167-5877(94)90073-6
  488. McDermott Patrick F., Tyson Gregory H., Kabera Claudine, Chen Yuansha, Li Cong, Folster Jason P., Ayers Sherry L., Lam Claudia, Tate Heather P., Zhao Shaohua, Whole-Genome Sequencing for Detecting Antimicrobial Resistance in Nontyphoidal Salmonella: TABLE 1, 10.1128/aac.01030-16
  489. McEwen Bruce S., Stress and the Individual : Mechanisms Leading to Disease, 10.1001/archinte.1993.00410180039004
  490. McEWEN BRUCE S., Stress, Adaptation, and Disease: Allostasis and Allostatic Load, 10.1111/j.1749-6632.1998.tb09546.x
  491. McIlroy S., McCracken R., Neill S., O'Brien J., Control, prevention and eradication of Salmonella enteritidis infection in broiler and broiler breeder flocks, 10.1136/vr.125.22.545
  492. Mee John F., Geraghty Tim, O’Neill Ronan, More Simon J., Bioexclusion of diseases from dairy and beef farms: Risks of introducing infectious agents and risk reduction strategies, 10.1016/j.tvjl.2012.07.001
  493. Mee‐Marquet, Frontiers in Microbiology, 5, 652 (2014)
  494. Meeusen E. N. T., Walker J., Peters A., Pastoret P.-P., Jungersen G., Current Status of Veterinary Vaccines, 10.1128/cmr.00005-07
  495. Melkebeek Vesna, Goddeeris Bruno M., Cox Eric, ETEC vaccination in pigs, 10.1016/j.vetimm.2012.09.024
  496. Melo, Canadian Journal of Veterinary Research, 79, 285 (2015)
  497. Menanteau-Ledouble S, Krauss I, Santos G, Fibi S, Weber B, El-Matbouli M, Effect of a phytogenic feed additive on the susceptibility of Onchorhynchus mykiss to Aeromonas salmonicida, 10.3354/dao02875
  498. Mench J.A., Broiler breeders: feed restriction and welfare, 10.1079/wps20020004
  499. Meszaros J., Stipkovits L., Antal T., Szabo I., Veszely P., Eradication of some infectious pig diseases by perinatal tiamulin treatment and early weaning, 10.1136/vr.116.1.8
  500. Meunier-Salaün M.C., Edwards S.A., Robert S., Effect of dietary fibre on the behaviour and health of the restricted fed sow, 10.1016/s0377-8401(01)00196-1
  501. Midtlyng Paul J, Grave Kari, Horsberg Tor Einar, What has been done to minimize the use of antibacterial and antiparasitic drugs in Norwegian aquaculture? : Minimize the use of antibacterial and antiparasitic drugs, 10.1111/j.1365-2109.2010.02726.x
  502. Miglior F., Muir B.L., Van Doormaal B.J., Selection Indices in Holstein Cattle of Various Countries, 10.3168/jds.s0022-0302(05)72792-2
  503. Miglior, Interbull Bulletin, 48, 73 (2014)
  504. Millman, F1000Research, 2, 155 (2013)
  505. Minton, Journal of Animal Science, 72, 1891 (1994)
  506. MIRANDA J. M., GUARDDON M., MONDRAGÓN A., VÁZQUEZ B. I., FENTE C. A., CEPEDA A., FRANCO C. M., Antimicrobial Resistance in Enterococcus spp. Strains Isolated from Organic Chicken, Conventional Chicken, and Turkey Meat: A Comparative Survey, 10.4315/0362-028x-70.4.1021
  507. Miranda J.M., Guarddon M., Vázquez B.I., Fente C.A., Barros-Velázquez J., Cepeda A., Franco C.M., Antimicrobial resistance in Enterobacteriaceae strains isolated from organic chicken, conventional chicken and conventional turkey meat: A comparative survey, 10.1016/j.foodcont.2007.05.002
  508. Miranda J. M., Vázquez B. I., Fente C. A., Barros-Velázquez J., Cepeda A., Franco Abuín C. M., Antimicrobial resistance in Escherichia coli strains isolated from organic and conventional pork meat: a comparative survey, 10.1007/s00217-006-0547-y
  509. Moennig Volker, Houe Hans, Lindberg Ann, BVD control in Europe: current status and perspectives, 10.1079/ahr2005102
  510. Moinard C, Mendl M, Nicol C.J, Green L.E, A case control study of on-farm risk factors for tail biting in pigs, 10.1016/s0168-1591(02)00276-9
  511. Mojsoska Biljana, Jenssen Håvard, Peptides and Peptidomimetics for Antimicrobial Drug Design, 10.3390/ph8030366
  512. Molbak K., Simonsen J., Jorgensen C. S., Krogfelt K. A., Falkenhorst G., Ethelberg S., Takkinen J., Emborg H.-D., Seroincidence of Human Infections With Nontyphoid Salmonella Compared With Data From Public Health Surveillance and Food Animals in 13 European Countries, 10.1093/cid/ciu627
  513. Molla B., Berhanu A., Muckle A., Cole L., Wilkie E., Kleer J., Hildebrandt G., Multidrug Resistance and Distribution of Salmonella Serovars in Slaughtered Pigs, 10.1111/j.1439-0450.2006.00900.x
  514. Mollenkopf Dixie F., Cenera Johana K., Bryant Erin M., King Christy A., Kashoma Isaac, Kumar Anand, Funk Julie A., Rajashekara Gireesh, Wittum Thomas E., Organic or Antibiotic-Free Labeling Does Not Impact the Recovery of Enteric Pathogens and Antimicrobial-ResistantEscherichia colifrom Fresh Retail Chicken, 10.1089/fpd.2014.1808
  515. Monnet D. L., Ferech M., Frimodt-Moller N., Goossens H., The More Antibacterial Trade Names, The More Consumption of Antibacterials: A European Study, 10.1086/430822
  516. Moore Dale A., Merryman Marcia L., Hartman Marla L., Klingborg Donald J., Comparison of published recommendations regarding biosecurity practices for various production animal species and classes, 10.2460/javma.233.2.249
  517. MOQUET P.C.A., ONRUST L., VAN IMMERSEEL F., DUCATELLE R., HENDRIKS W.H., KWAKKEL R.P., Importance of release location on the mode of action of butyrate derivatives in the avian gastrointestinal tract, 10.1017/s004393391500269x
  518. More SJ, Global trends in milk quality: implications for the irish dairy industry, 10.1186/2046-0481-62-s4-s5
  519. More S. J., Radunz B., Glanville R. J., Lessons learned during the successful eradication of bovine tuberculosis from Australia, 10.1136/vr.103163
  520. Moreno M. A., Survey of quantitative antimicrobial consumption in two different pig finishing systems, 10.1136/vr.100818
  521. Moreno Miguel A., Opinions of Spanish pig producers on the role, the level and the risk to public health of antimicrobial use in pigs, 10.1016/j.rvsc.2014.04.006
  522. Moreno Miguel A., Survey of quantitative antimicrobial consumption per production stage in farrow-to-finish pig farms in Spain, 10.1136/vropen-2013-000002
  523. Morris C.A., A review of genetic resistance to disease in Bos taurus cattle, 10.1016/j.tvjl.2006.09.006
  524. Mortensen Sten, Stryhn Henrik, Søgaard Rikke, Boklund Anette, Stärk Katharina D.C, Christensen Jette, Willeberg Preben, Risk factors for infection of sow herds with porcine reproductive and respiratory syndrome (PRRS) virus, 10.1016/s0167-5877(01)00260-4
  525. Mourão J., Machado J., Novais C., Antunes P., Peixe L., Characterization of the emerging clinically-relevant multidrug-resistant Salmonella enterica serotype 4,[5],12:i:- (monophasic variant of S. Typhimurium) clones, 10.1007/s10096-014-2180-1
  526. Mourão Joana, Novais Carla, Machado Jorge, Peixe Luísa, Antunes Patrícia, Metal tolerance in emerging clinically relevant multidrug-resistant Salmonella enterica serotype 4,[5],12:i:− clones circulating in Europe, 10.1016/j.ijantimicag.2015.01.013
  527. Mrode R and Swanson G, 1996. Genetic and statistical properties of somatic cell count and its suitability as an indirect means of reducing the incidence of mastitis in dairy cattle. Animal Breeding Abstracts (United Kingdom).
  528. MULERO V., ESTEBAN M.A., MUÑOZ J., MESEGUER J., Dietary intake of levamisole enhances the immune response and disease resistance of the marine teleost gilthead seabream (Sparus aurataL.), 10.1006/fsim.1997.0119
  529. Muller T., Batza H.-J., Schluter H., Conraths F. J., Mettenleiter T. C., Eradication of Aujeszky's Disease in Germany, 10.1046/j.1439-0450.2003.00666.x
  530. Munsterhjelm Camilla, Peltoniemi Olli A.T., Heinonen Mari, Hälli Outi, Karhapää Maija, Valros Anna, Experience of moderate bedding affects behaviour of growing pigs, 10.1016/j.applanim.2009.01.007
  531. Musliner K. L., Seifuddin F., Judy J. A., Pirooznia M., Goes F. S., Zandi P. P., Polygenic risk, stressful life events and depressive symptoms in older adults: a polygenic score analysis, 10.1017/s0033291714002839
  532. Nederlandstalige Gewestelijke Raad van de Orde der Dierenartsen 2015. Code der plichtenleer.
  533. Nelson J. M., Chiller T. M., Powers J. H., Angulo F. J., Fluoroquinolone-Resistant Campylobacter Species and the Withdrawal of Fluoroquinolones from Use in Poultry: A Public Health Success Story, 10.1086/512369
  534. Nesbakken T, 2012. Specific Pathogen‐Free (SPF) pig herds also free from zoonotic agents? Proceedings of the International Conference Biological Food Safety and Quality.
  535. Netea M. G., Joosten L. A. B., Latz E., Mills K. H. G., Natoli G., Stunnenberg H. G., ONeill L. A. J., Xavier R. J., Trained immunity: A program of innate immune memory in health and disease, 10.1126/science.aaf1098
  536. Newberry Ruth C., Environmental enrichment: Increasing the biological relevance of captive environments, 10.1016/0168-1591(95)00616-z
  537. Nhung Nguyen, Thuy Cao, Trung Nguyen, Campbell James, Baker Stephen, Thwaites Guy, Hoa Ngo, Carrique-Mas Juan, Induction of Antimicrobial Resistance in Escherichia coli and Non-Typhoidal Salmonella Strains after Adaptation to Disinfectant Commonly Used on Farms in Vietnam, 10.3390/antibiotics4040480
  538. NICE (National Institute for Health and Care Excellence), 2015. Antimicrobial stewardship: systems and processes for effective antimicrobial medicine use. Available online:
  539. NICHOLLS T.J., ACAR J., ANTHONY F., FRANKLIN A., GUPTA R., TAMURA Y., THOMPSON S., THRELFALL E.J., VOSE D.J., VAN VUUREN M., WHITE D.G., WEGENER H.C., COSTARRICA M.L., Antimicrobial resistance: monitoring the quantities of antimicrobials used in animal husbandry : -EN- -FR- -ES-, 10.20506/rst.20.3.1317
  540. Nielsen S.S., Toft N., Effect of management practices on paratuberculosis prevalence in Danish dairy herds, 10.3168/jds.2010-3817
  541. Nielsen Liza Rosenbaum, Nielsen Søren Saxmose, A structured approach to control of Salmonella Dublin in 10 Danish dairy herds based on risk scoring and test-and-manage procedures, 10.1016/j.foodres.2011.02.027
  542. Niewold T.A., van Dijk A.J., Geenen P.L., Roodink H., Margry R., van der Meulen J., Dietary specific antibodies in spray-dried immune plasma prevent enterotoxigenic Escherichia coli F4 (ETEC) post weaning diarrhoea in piglets, 10.1016/j.vetmic.2007.04.034
  543. Nilsen Einar, Automated identification and susceptibility determination directly from blood cultures facilitates early targeted antibiotic therapy, 10.3109/00365548.2012.689848
  544. NORM/NORM‐VET , 2015. NORM/NORM‐VET 2014. Usage of Antimicrobial Agents and Occurrence of Antimicrobial Resistance in Norway. Tromsø / Oslo. Available online:
  545. Nulsen MF, Mor MB, Lawton DEB, Antibiotic resistance among indicator bacteria isolated from healthy pigs in New Zealand, 10.1080/00480169.2008.36801
  546. Nuotio Lasse, Neuvonen Erkki, Hyytiäinen Mauno, 10.1186/1751-0147-49-3
  547. NURMI E., RANTALA M., New Aspects of Salmonella Infection in Broiler Production, 10.1038/241210a0
  548. Nya E.J., Austin B., Use of bacterial lipopolysaccharide (LPS) as an immunostimulant for the control ofAeromonas hydrophilainfections in rainbow troutOncorhynchus mykiss(Walbaum), 10.1111/j.1365-2672.2009.04464.x
  549. O'Neill J 2015. Antimicrobials in Agriculture and the Environment: Reducing Unnecessary Use and Waste ‐ The Review on Antimicrobial Resistance ‐ December 2015. Available online:
  550. O'Neill J, 2016. Tackling drug‐resistant infections globally: final report and recommendations. The review on antimicrobial resistance. Chaired by Jim O'Neill. May 2016. Available online:
  551. Oelschlaeger Tobias A., Mechanisms of probiotic actions – A review, 10.1016/j.ijmm.2009.08.005
  552. OIE (World Organisation for Animal Health), 2012. Checklist on the Practical Application of Compartmentalisation. Available online:
  553. OIE (World Organisation for Animal Health), 2015. Resolution No 26: Combating Antimicrobial Resistance and Promoting the Prudent Use of Antimicrobial Agents in Animals. Available online:
  554. OIE (World Organisation for Animal Health), 2016. Resolution No 36: Combating Antimicrobial Resistance through a One Health Approach: Actions and OIE Strategy. Available online:
  555. Oliveira J., Castilho F., Cunha A., Pereira M. J., Bacteriophage therapy as a bacterial control strategy in aquaculture, 10.1007/s10499-012-9515-7
  556. Oliver W. T., Wells J. E., Lysozyme as an alternative to growth promoting antibiotics in swine production, 10.1186/s40104-015-0034-z
  557. Orda J., Jamroz D., Wiliczkiewicz A., Skorupińska J., Kubizna J., The influence of porcine blood by-products on laying hen performance, egg quality, and yolk mineral content, 10.22358/jafs/66056/2012
  558. Österberg Julia, Wingstrand Anne, Nygaard Jensen Annette, Kerouanton Annaelle, Cibin Veronica, Barco Lisa, Denis Martine, Aabo Sören, Bengtsson Björn, Antibiotic Resistance in Escherichia coli from Pigs in Organic and Conventional Farming in Four European Countries, 10.1371/journal.pone.0157049
  559. Overdevest Ilse, Extended-Spectrum B-Lactamase Genes of Escherichia coli in Chicken Meat and Humans, the Netherlands, 10.3201/eid1707.110209
  560. Pai Srinivas Somnath, Anas Abdulaziz, Jayaprakash Natamai Subramaniam, Priyaja Prabhakaran, Sreelakshmi Balachandran, Preetha Radhakrishnan, Philip Rosamma, Mohandas Ambat, Singh Isaac Sarogeni Bright, Penaeus monodon larvae can be protected from Vibrio harveyi infection by pre-emptive treatment of a rearing system with antagonistic or non-antagonistic bacterial probiotics : Probiotic treatment of Penaeus monodon larvae, 10.1111/j.1365-2109.2009.02362.x
  561. Pajor E.A, Rushen J, de Passillé A.M.B, Aversion learning techniques to evaluate dairy cattle handling practices, 10.1016/s0168-1591(00)00119-2
  562. Papatsiros V, Alternatives to antibiotics for farm animals., 10.1079/pavsnnr20138032
  563. Papich Mark G., Pharmacokinetic–pharmacodynamic (PK–PD) modeling and the rational selection of dosage regimes for the prudent use of antimicrobial drugs, 10.1016/j.vetmic.2013.12.021
  564. Pappas Georgios, Papadimitriou Photini, Akritidis Nikolaos, Christou Leonidas, Tsianos Epameinondas V, The new global map of human brucellosis, 10.1016/s1473-3099(06)70382-6
  565. Pardon B., Catry B., Dewulf J., Persoons D., Hostens M., De Bleecker K., Deprez P., Prospective study on quantitative and qualitative antimicrobial and anti-inflammatory drug use in white veal calves, 10.1093/jac/dkr570
  566. Pardon Bart, De Bleecker Koen, Hostens Miel, Callens Jozefien, Dewulf Jeroen, Deprez Piet, Longitudinal study on morbidity and mortality in white veal calves in Belgium, 10.1186/1746-6148-8-26
  567. Pardon, Vlaams Diergeneeskundig Tijdschrift, 83, 155 (2014)
  568. Park Young Kyung, Fox Lawrence K., Hancock Dale D., McMahan Wade, Park Yong Ho, Prevalence and antibiotic resistance of mastitis pathogens isolated from dairy herds transitioning to organic management, 10.4142/jvs.2012.13.1.103
  569. Payne C. G., Practical Aspects of Environmental Temperature for Laying Hens, 10.1079/wps19660020
  570. Pedersen Ken Steen, Okholm Elisabeth, Johansen Markku, Angen Øystein, Jorsal Sven Erik, Nielsen Jens Peter, Bækbo Poul, Clinical utility and performance of sock sampling in weaner pig diarrhoea, 10.1016/j.prevetmed.2015.04.015
  571. Straw, Diseases of Swine, 419 (2006)
  572. Peng Luying, He Zhenjuan, Chen Wei, Holzman Ian R, Lin Jing, Effects of Butyrate on Intestinal Barrier Function in a Caco-2 Cell Monolayer Model of Intestinal Barrier, 10.1203/01.pdr.0000250014.92242.f3
  573. Pensaert M., Gielkens A.L.J., Lomniczi B., Kimman T.G., Vannier P., Eloit M., Round table on control of Aujeszky's disease and vaccine development based on molecular biology, 10.1016/0378-1135(92)90035-r
  574. Pensaert, Developments in Biologicals, 119, 243 (2003)
  575. Persoons Davy, Dewulf Jeroen, Smet Annemieke, Herman Lieve, Heyndrickx Marc, Martel An, Catry Boudewijn, Butaye Patrick, Haesebrouck Freddy, Antimicrobial use in Belgian broiler production, 10.1016/j.prevetmed.2012.02.020
  576. Pettey Jeff H., Mifflin Mark D., Olson Randall J., Study of the Acute Effects of Povidone–Iodine on Conjunctival Bacterial Flora, 10.1089/jop.2015.0079
  577. Pham Dominique, Ansquer Dominique, Chevalier Anne, Dauga Clément, Peyramale Aude, Wabete Nelly, Labreuche Yannick, Selection and characterization of potential probiotic bacteria for Litopenaeus stylirostris shrimp hatcheries in New Caledonia, 10.1016/j.aquaculture.2014.04.031
  578. Pijpers A, Schoevers E J, van Gogh H, van Leengoed L A, Visser I J, van Miert A S, Verheijden J H, The influence of disease on feed and water consumption and on pharmacokinetics of orally administered oxytetracycline in pigs., 10.2527/1991.6972947x
  579. Piper Clare, Cotter Paul, Ross R., Hill Colin, Discovery of Medically Significant Lantibiotics, 10.2174/157016309787581075
  580. Pluske John R, Feed- and feed additives-related aspects of gut health and development in weanling pigs, 10.1186/2049-1891-4-1
  581. Poirel Laurent, Nordmann Patrice, Emerging plasmid-encoded colistin resistance: the animal world as the culprit?, 10.1093/jac/dkw074
  582. Pokludova L, Nedbalcova K, Dubska M, Cerny T, Bures J and Satran P, 2016. The Czech Republic national programme of monitoring antimicrobial resistance of pathogens with veterinary importance. 8th AAVM conference, Budapest, Hungary, August 2016.
  583. Pol M., Ruegg P.L., Relationship Between Antimicrobial Drug Usage and Antimicrobial Susceptibility of Gram-Positive Mastitis Pathogens, 10.3168/jds.s0022-0302(07)72627-9
  584. Pol M., Ruegg P.L., Treatment Practices and Quantification of Antimicrobial Drug Usage in Conventional and Organic Dairy Farms in Wisconsin, 10.3168/jds.s0022-0302(07)72626-7
  585. Poppe, Canadian Journal of Veterinary Research‐Revue Canadienne De Recherche Veterinaire, 70, 105 (2006)
  586. Postma Merel, Sjölund Marie, Collineau Lucie, Lösken Svenja, Stärk Katharina D. C., Dewulf Jeroen, Andreasen Margit, Backhans Annette, Belloc Catherine, Collineau Lucie, Dewulf Jeroen, Emanuelson Ulf, Beilage Elisabeth Grosse, Liesner Bernd Grosse, Körk Christian Alexander, Lindberg Ann, Lösken Svenja, Postma Merel, Seemer Hugo, Sjölund Marie, Stärk Katharina, Visschers Vivianne, Assigning defined daily doses animal: a European multi-country experience for antimicrobial products authorized for usage in pigs *, 10.1093/jac/dku347
  587. Postma Merel, Stärk Katharina D.C., Sjölund Marie, Backhans Annette, Beilage Elisabeth Grosse, Lösken Svenja, Belloc Catherine, Collineau Lucie, Iten Denise, Visschers Vivianne, Nielsen Elisabeth O., Dewulf Jeroen, Alternatives to the use of antimicrobial agents in pig production: A multi-country expert-ranking of perceived effectiveness, feasibility and return on investment, 10.1016/j.prevetmed.2015.01.010
  588. Postma M., Speksnijder D. C., Jaarsma A. D. C., Verheij T. J. M., Wagenaar J. A., Dewulf J., Opinions of veterinarians on antimicrobial use in farm animals in Flanders and the Netherlands, 10.1136/vr.103618
  589. Postma M, Vanderhaeghen W, Sarrazin S, Maes D and Dewulf J, 2016b. Reducing Antimicrobial Usage in Pig Production without Jeopardizing Production Parameters. Zoonoses Public Health, online ahead of print.
  590. Prasad, Journal of Environmental Biology, 32, 161 (2011)
  591. Price Lance B., Johnson Elizabeth, Vailes Rocio, Silbergeld Ellen, Fluoroquinolone-Resistant Campylobacter Isolates from Conventional and Antibiotic-Free Chicken Products, 10.1289/ehp.7647
  592. Prunier A., Heinonen M., Quesnel H., High physiological demands in intensively raised pigs: impact on health and welfare, 10.1017/s175173111000008x
  593. Public Health Agency of Sweden and SVA (National Veterinary Institute), 2015. Swedres‐Svarm 2014 – Consumption of antibiotics and occurrence of antibiotic resistance in Sweden. Available online:
  594. Public Health Agency of Sweden and SVA (National Veterinary Institute), 2016. Swedres‐Svarm 2015 – Consumption of antibiotics and occurrence of antibiotic resistance in Sweden 2015. Available online:
  595. Pulcini Céline, Gyssens Inge C., How to educate prescribers in antimicrobial stewardship practices, 10.4161/viru.23706
  596. QAISRANI S.N., VAN KRIMPEN M.M., KWAKKEL R.P., VERSTEGEN M.W.A., HENDRIKS W.H., Dietary factors affecting hindgut protein fermentation in broilers: a review, 10.1017/s0043933915000124
  597. Quigley III J. D., Drew M. D., Effects of Oral Antibiotics or Bovine Plasma on Survival, Health and Growth in Dairy Calves Challenged withEscherichia coli, 10.1080/09540100020008173
  598. Quinteiro-Filho W. M., Ribeiro A., Ferraz-de-Paula V., Pinheiro M. L., Sakai M., Sa L. R. M., Ferreira A. J. P., Palermo-Neto J., Heat stress impairs performance parameters, induces intestinal injury, and decreases macrophage activity in broiler chickens, 10.3382/ps.2010-00812
  599. Rabiee A.R., Lean I.J., The effect of internal teat sealant products (Teatseal and Orbeseal) on intramammary infection, clinical mastitis, and somatic cell counts in lactating dairy cows: A meta-analysis, 10.3168/jds.2013-6544
  600. Radostits, Veterinary medicine: a textbook of the diseases of cattle, sheep, goats, pigs and horses (2007)
  601. Raith J., Trauffler M., Firth C. L., Lebl K., Schleicher C., Köfer J., Influence of porcine circovirus type 2 vaccination on the level of antimicrobial consumption on 65 Austrian pig farms, 10.1136/vr.103406
  602. Ramli N, Heindl U and Sunanto S, 2005. Effect of potassium‐diformate on growth performance of tilapia challenged with Vibrio anguillarum. Abstract, World Aquaculture Society, World Aquaculture 2005, May 9–13, 2005, Bali, Indonesia.
  603. Randrianarivelo, Journal of Applied Microbiology, 109, 642 (2010)
  604. Rappuoli Rino, Bottomley Matthew J., D’Oro Ugo, Finco Oretta, De Gregorio Ennio, Reverse vaccinology 2.0: Human immunology instructs vaccine antigen design, 10.1084/jem.20151960
  605. RASSCHAERT G., MICHIELS J., TAGLIABUE M., MISSOTTEN J., DE SMET S., HEYNDRICKX M., Effect of Organic Acids on Salmonella Shedding and Colonization in Pigs on a Farm with High Salmonella Prevalence, 10.4315/0362-028x.jfp-15-183
  606. Rautiainen E, Oravainen J, Virolainen JV, Tuovinen V, 10.1186/1751-0147-42-355
  607. Ray K.A., Warnick L.D., Mitchell R.M., Kaneene J.B., Ruegg P.L., Wells S.J., Fossler C.P., Halbert L.W., May K., Antimicrobial Susceptibility of Salmonella from Organic and Conventional Dairy Farms, 10.3168/jds.s0022-0302(06)72271-8
  608. RDA (Raad voor Dierenaangelegenheden), 2016. Antibioicabeleid in de Dierhouderij – Effectten en Perspectieven. Available online:
  609. Redondo Leandro M., Chacana Pablo A., Dominguez Johana E., Fernandez Miyakawa Mariano E., Perspectives in the use of tannins as alternative to antimicrobial growth promoter factors in poultry, 10.3389/fmicb.2014.00118
  610. Reid Gregor, Younes Jessica A., Van der Mei Henny C., Gloor Gregory B., Knight Rob, Busscher Henk J., Microbiota restoration: natural and supplemented recovery of human microbial communities, 10.1038/nrmicro2473
  611. Renoux G, 1978. Modulation of immunity by levamisole. Pharmacology & Therapeutics Part a‐Chemotherapy Toxicology and Metabolic Inhibitors, 2, 397–423.
  612. Reverter M., Bontemps N., Lecchini D., Banaigs B., Sasal P., Use of plant extracts in fish aquaculture as an alternative to chemotherapy: Current status and future perspectives, 10.1016/j.aquaculture.2014.05.048
  613. Reynolds D. J., Davies R. H., Richards M., Wray C., Evaluation of combined antibiotic and competitive exclusion treatment in broiler breeder flocks infected withSalmonella entericaserovar Enteritidis, 10.1080/03079459708419196
  614. Riber Ulla, Heegaard Peter M.H., Cordes Henriette, Ståhl Marie, Jensen Tim Kåre, Jungersen Gregers, Vaccination of pigs with attenuated Lawsonia intracellularis induced acute phase protein responses and primed cell-mediated immunity without reduction in bacterial shedding after challenge, 10.1016/j.vaccine.2014.10.084
  615. Ricke S. C., Potential of fructooligosaccharide prebiotics in alternative and nonconventional poultry production systems, 10.3382/ps/pev049
  616. Rinsky Jessica L., Nadimpalli Maya, Wing Steve, Hall Devon, Baron Dothula, Price Lance B., Larsen Jesper, Stegger Marc, Stewart Jill, Heaney Christopher D., Livestock-Associated Methicillin and Multidrug Resistant Staphylococcus aureus Is Present among Industrial, Not Antibiotic-Free Livestock Operation Workers in North Carolina, 10.1371/journal.pone.0067641
  617. Roberfroid, Journal of Nutrition, 137, 830S (2007)
  618. Robertson R and Jochelson K, 2006. Interventions that change clinician behaviour: mapping the literature. National Institute of Clinical Excellence (NICE).
  619. Rodenburg T. B., Turner S. P., The role of breeding and genetics in the welfare of farm animals, 10.2527/af.2012-0044
  620. Roelvink J, 2015. Association between farm management practices and the development of disease in the digestive and respiratory tract in young stock on Dutch dairy farms.
  621. Roesch M., Perreten V., Doherr M.G., Schaeren W., Schällibaum M., Blum J.W., Comparison of Antibiotic Resistance of Udder Pathogens in Dairy Cows Kept on Organic and on Conventional Farms, 10.3168/jds.s0022-0302(06)72164-6
  622. Rosell J.M., de la Fuente L.F., Causes of mortality in breeding rabbits, 10.1016/j.prevetmed.2016.03.014
  623. Rossiter, The Bovine Practitioner, 33, 1 (1999)
  624. Rothrock Michael J., Ingram Kimberly D., Gamble John, Guard Jean, Cicconi-Hogan Kellie M., Hinton Arthur, Hiett Kelli L., The characterization ofSalmonella entericaserotypes isolated from the scalder tank water of a commercial poultry processing plant: Recovery of a multidrug-resistant Heidelberg strain, 10.3382/ps/peu060
  625. Rothrock Michael J., Hiett Kelli L., Guard Jean Y., Jackson Charlene R., Antibiotic Resistance Patterns of Major Zoonotic Pathogens from All-Natural, Antibiotic-Free, Pasture-Raised Broiler Flocks in the Southeastern United States, 10.2134/jeq2015.07.0366
  626. Rousing T, Waiblinger S, Evaluation of on-farm methods for testing the human–animal relationship in dairy herds with cubicle loose housing systems—test–retest and inter-observer reliability and consistency to familiarity of test person, 10.1016/j.applanim.2003.09.014
  627. Routh, Epidemiology and Infection, 1 (2015)
  628. Rugna G., Bonilauri P., Carra E., Bergamini F., Luppi A., Gherpelli Y., Magistrali C.F., Nigrelli A., Alborali G.L., Martelli P., La T., Hampson D.J., Merialdi G., Sequence types and pleuromutilin susceptibility of Brachyspira hyodysenteriae isolates from Italian pigs with swine dysentery: 2003–2012, 10.1016/j.tvjl.2014.10.033
  629. Ryder A. B., Huang Y., Li H., Zheng M., Wang X., Stratton C. W., Xu X., Tang Y.-W., Assessment of Clostridium difficile Infections by Quantitative Detection of tcdB Toxin by Use of a Real-Time Cell Analysis System, 10.1128/jcm.01104-10
  630. Saad N., Delattre C., Urdaci M., Schmitter J.M., Bressollier P., An overview of the last advances in probiotic and prebiotic field, 10.1016/j.lwt.2012.05.014
  631. Saastamoinen Markku, Särkijärvi Susanna, Hyyppä Seppo, Reducing Respiratory Health Risks to Horses and Workers: A Comparison of Two Stall Bedding Materials, 10.3390/ani5040394
  632. Saitone Tina L., Sexton Richard J., Sumner Daniel A., What Happens When Food Marketers Require Restrictive Farming Practices?, 10.1093/ajae/aav021
  633. Salaheen S., Chowdhury N., Hanning I., Biswas D., Zoonotic bacterial pathogens and mixed crop-livestock farming: Table 1., 10.3382/ps/peu055
  634. Salak-Johnson J. L., McGlone J. J., Making sense of apparently conflicting data: Stress and immunity in swine and cattle, 10.2527/jas.2006-538
  635. Sanad Yasser M., Johnson Kelly, Park Si Hong, Han Jing, Deck Joanna, Foley Steven L., Kenney Brett, Ricke Steven, Nayak Rajesh, Molecular Characterization ofSalmonella entericaSerovars Isolated from a Turkey Production Facility in the Absence of Selective Antimicrobial Pressure, 10.1089/fpd.2015.2002
  636. Sandiford Stephanie Kate, Perspectives on lantibiotic discovery – where have we failed and what improvements are required?, 10.1517/17460441.2015.1016496
  637. Santman-Berends I.M.G.A., Swinkels J.M., Lam T.J.G.M., Keurentjes J., van Schaik G., Evaluation of udder health parameters and risk factors for clinical mastitis in Dutch dairy herds in the context of a restricted antimicrobial usage policy, 10.3168/jds.2015-10398
  638. Sanz Susana, Olarte Carmen, Martínez-Olarte Roberto, Navajas-Benito Enrique V., Alonso C. Andrea, Hidalgo-Sanz Sara, Somalo Sergio, Torres Carmen, Airborne dissemination of Escherichia coli in a dairy cattle farm and its environment, 10.1016/j.ijfoodmicro.2014.12.010
  639. Sapkota Amir, Sapkota Amy R., Kucharski Margaret, Burke Janelle, McKenzie Shawn, Walker Polly, Lawrence Robert, Aquaculture practices and potential human health risks: Current knowledge and future priorities, 10.1016/j.envint.2008.04.009
  640. Sapkota Amy R., Hulet R. Michael, Zhang Guangyu, McDermott Patrick, Kinney Erinna L., Schwab Kellogg J., Joseph Sam W., Lower Prevalence of Antibiotic-Resistant Enterococci on U.S. Conventional Poultry Farms that Transitioned to Organic Practices, 10.1289/ehp.1003350
  641. Sapkota Amy R., Kinney Erinna L., George Ashish, Hulet R. Michael, Cruz-Cano Raul, Schwab Kellogg J., Zhang Guangyu, Joseph Sam W., Lower prevalence of antibiotic-resistant Salmonella on large-scale U.S. conventional poultry farms that transitioned to organic practices, 10.1016/j.scitotenv.2013.12.005
  642. Sargeant Hannah R., McDowall Kenneth J., Miller Helen M., Shaw Marie-Anne, Dietary zinc oxide affects the expression of genes associated with inflammation: Transcriptome analysis in piglets challenged with ETEC K88, 10.1016/j.vetimm.2010.05.001
  643. Sarmah Ajit K., Meyer Michael T., Boxall Alistair B.A., A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment, 10.1016/j.chemosphere.2006.03.026
  644. SASAKI Yosuke, SEKIGUCHI Satoshi, UEMURA Ryoko, SUEYOSHI Masuo, The effect of depopulation and restocking on reproductive and growth performances on Japanese commercial swine farms, 10.1292/jvms.15-0013
  645. Sato K., Bartlett P. C., Kaneene J. B., Downes F. P., Comparison of Prevalence and Antimicrobial Susceptibilities of Campylobacter spp. Isolates from Organic and Conventional Dairy Herds in Wisconsin, 10.1128/aem.70.3.1442-1447.2004
  646. Sato Kenji, Bartlett Paul C., Saeed Mahdi A., Antimicrobial susceptibility of Escherichia coli isolates from dairy farms using organic versus conventional production methods, 10.2460/javma.2005.226.589
  647. SCAHAW (Scientific Committee on Animal Health and Welfare), 2002. Report of the Scientific Committee on Animal Health and Welfare ‐ The welfare of animals during transport (details for horses, pigs, sheep and cattle). European Commission – Health and Consumer Protection Directorate‐General. Directorate C–Scientific Opinions.
  648. Scalbert Augustin, Antimicrobial properties of tannins, 10.1016/0031-9422(91)83426-l
  649. Schauber J, Expression of the cathelicidin LL-37 is modulated by short chain fatty acids in colonocytes: relevance of signalling pathways, 10.1136/gut.52.5.735
  650. Scherpenzeel C.G. M., den Uijl I.E. M., van Schaik G., Olde Riekerink R.G. M., Keurentjes J.M., Lam T.J.G. M., Evaluation of the use of dry cow antibiotics in low somatic cell count cows, 10.3168/jds.2013-7655
  651. Scherpenzeel C.G.M., den Uijl I.E.M., van Schaik G., Riekerink R.G.M.Olde, Hogeveen H., Lam T.J.G.M., Effect of different scenarios for selective dry-cow therapy on udder health, antimicrobial usage, and economics, 10.3168/jds.2015-9963
  652. Schirrmeier H, 2014. Three years of mandatory BVD control in Germany – Lessons to be learned. Proceedings of the XXVIII World Buiatrics Congress, Cairns 2014.
  653. Schokker Dirkjan, Zhang Jing, Zhang Ling-li, Vastenhouw Stéphanie A., Heilig Hans G. H. J., Smidt Hauke, Rebel Johanna M. J., Smits Mari A., Early-Life Environmental Variation Affects Intestinal Microbiota and Immune Development in New-Born Piglets, 10.1371/journal.pone.0100040
  654. Schokker Dirkjan, Veninga Gosse, Vastenhouw Stephanie A., Bossers Alex, de Bree Freddy M., Kaal-Lansbergen Lucia M. T. E., Rebel Johanna M. J., Smits Mari A., Early life microbial colonization of the gut and intestinal development differ between genetically divergent broiler lines, 10.1186/s12864-015-1646-6
  655. Schokker Dirkjan, Zhang Jing, Vastenhouw Stéphanie A., Heilig Hans G. H. J., Smidt Hauke, Rebel Johanna M. J., Smits Mari A., Long-Lasting Effects of Early-Life Antibiotic Treatment and Routine Animal Handling on Gut Microbiota Composition and Immune System in Pigs, 10.1371/journal.pone.0116523
  656. Schulte Jasper N., Brockmann Gudrun A., Kreuzer-Redmer Susanne, Feeding a high dosage of zinc oxide affects suppressor of cytokine gene expression in Salmonella Typhimurium infected piglets, 10.1016/j.vetimm.2016.06.009
  657. Schwaiger K., Schmied E.-M. V., Bauer J., Comparative Analysis on Antibiotic Resistance Characteristics ofListeriaspp. andEnterococcusspp. Isolated From Laying Hens and Eggs in Conventional and Organic Keeping Systems in Bavaria, Germany, 10.1111/j.1863-2378.2008.01229.x
  658. Schwartz K, Henry S, Tokach L, Potter M, Davidson D, Egnor C and PFFJ L, 2013. Infective material, concepts and procedures for intentional sow herd exposure to Porcine Epidemic Diarrhea virus. Iowa State University, 8.
  659. Scicluna Maria Teresa, Issel Charles J., Cook Frank R., Manna Giuseppe, Cersini Antonella, Rosone Francesca, Frontoso Raffaele, Caprioli Andrea, Antonetti Valeria, Autorino Gian Luca, Is a diagnostic system based exclusively on agar gel immunodiffusion adequate for controlling the spread of equine infectious anaemia?, 10.1016/j.vetmic.2013.02.027
  660. SDa (Netherlands Veterinary Medicines Authority), 2013. Het gebruik van fluorochinolonen en derde en vierde generatie cefalosporines in landbouwhuisdieren – Rapportage van het SDa expertpanel. Available online:
  661. SDa (Netherlands Veterinary Medicines Authority), 2016a. Associations between antimicrobial use and the prevalence of resistant micro‐organisms – Is it possible to benchmark livestock farms based on resistance data? Available online:
  662. SDa (Netherlands Veterinary Medicines Authority), 2016b. Het gebruik van antibiotica bij landbouwhuisdieren in 2015 ‐ Trends, benchmarken bedrijven en dierenartsen, en aanpassing benchmarkwaardensystematiek. Available online:
  663. Monat, Stress and Coping, 17 (1985)
  664. Sellera Fábio Parra, Gargano Ronaldo Gomes, Libera Alice Maria Melville Paiva Della, Benesi Fernando José, Azedo Milton Ricardo, de Sá Lilian Rose Marques, Ribeiro Martha Simões, da Silva Baptista Maurício, Pogliani Fabio Celidonio, Antimicrobial photodynamic therapy for caseous lymphadenitis abscesses in sheep: Report of ten cases, 10.1016/j.pdpdt.2015.12.006
  665. Senatore Felice, Influence of Harvesting Time on Yield and Composition of the Essential Oil of a Thyme (ThymuspulegioidesL.) Growing Wild in Campania (Southern Italy), 10.1021/jf950508z
  666. Shang Yue, Regassa Alemu, Kim Ji Hyuk, Kim Woo Kyun, The effect of dietary fructooligosaccharide supplementation on growth performance, intestinal morphology, and immune responses in broiler chickens challenged withSalmonellaEnteritidis lipopolysaccharides, 10.3382/ps/pev275
  667. Shao Yujing, Wang Zhong, Tian Xiangyu, Guo Yuming, Zhang Haibo, Yeast β- d -glucans induced antimicrobial peptide expressions against Salmonella infection in broiler chickens, 10.1016/j.ijbiomac.2016.01.031
  668. Shea K. M., Nontherapeutic Use of Antimicrobial Agents in Animal Agriculture: Implications for Pediatrics, 10.1542/peds.2004-1233
  669. Shtrichman Ronit, Samuel Charles E, The role of gamma interferon in antimicrobial immunity, 10.1016/s1369-5274(00)00199-5
  670. Si W., Gong J., Tsao R., Zhou T., Yu H., Poppe C., Johnson R., Du Z., Antimicrobial activity of essential oils and structurally related synthetic food additives towards selected pathogenic and beneficial gut bacteria, 10.1111/j.1365-2672.2005.02789.x
  671. Sibley, In Practice, 0263841X, 22 (2000)
  672. Sibley, In Practice, 0263841X, 28 (2006)
  673. Siemon Cedarose Ethel, Bahnson Peter B., Gebreyes Wondwossen A., Comparative Investigation of Prevalence and Antimicrobial Resistance of Salmonella Between Pasture and Conventionally Reared Poultry, 10.1637/0005-2086(2007)051[0112:ciopaa];2
  674. Signorini M.L., Soto L.P., Zbrun M.V., Sequeira G.J., Rosmini M.R., Frizzo L.S., Impact of probiotic administration on the health and fecal microbiota of young calves: A meta-analysis of randomized controlled trials of lactic acid bacteria, 10.1016/j.rvsc.2011.05.001
  675. Silley Peter, de Jong Anno, Simjee Shabbir, Thomas Valérie, Harmonisation of resistance monitoring programmes in veterinary medicine: an urgent need in the EU?, 10.1016/j.ijantimicag.2010.12.002
  676. Silley, Revue scientifique et technique (International Office of Epizootics), 31, 105 (2012)
  677. Silva Marcus Leonardo Figueiredo, Lima José Augusto de Freitas, Cantarelli Vinícius de Souza, Amaral Níkolas de Oliveira, Zangerônimo Márcio Gilberto, Fialho Elias Tadeu, Probiotics and antibiotics as additives for sows and piglets during nursery phase, 10.1590/s1516-35982010001100019
  678. Silva Yolanda J., Moreirinha Catarina, Pereira Carla, Costa Liliana, Rocha Rui J.M., Cunha Ângela, Gomes Newton C.M., Calado Ricardo, Almeida Adelaide, Biological control of Aeromonas salmonicida infection in juvenile Senegalese sole ( Solea senegalensis ) with Phage AS-A, 10.1016/j.aquaculture.2015.07.025
  679. Šíma P., Trebichavský I., Sigler K., Mammalian antibiotic peptides, 10.1007/bf02930945
  680. Simoneit, vTI Agriculture and Forestry Research, 62, 97 (2012)
  681. Singh Elizabeth L., The disease control potential of embryos, 10.1016/0093-691x(87)90066-5
  682. Sjölund Marie, Backhans Annette, Greko Christina, Emanuelson Ulf, Lindberg Ann, Antimicrobial usage in 60 Swedish farrow-to-finish pig herds, 10.1016/j.prevetmed.2015.07.005
  683. Sjölund M., Postma M., Collineau L., Lösken S., Backhans A., Belloc C., Emanuelson U., Beilage E.Groβe, Stärk K., Dewulf J., Quantitative and qualitative antimicrobial usage patterns in farrow-to-finish pig herds in Belgium, France, Germany and Sweden, 10.1016/j.prevetmed.2016.06.003
  684. Skov Robert L., Monnet Dominique L., Plasmid-mediated colistin resistance (mcr-1gene): three months later, the story unfolds, 10.2807/
  685. Slifierz M. J., Friendship R., Weese J. S., Zinc Oxide Therapy Increases Prevalence and Persistence of Methicillin-ResistantStaphylococcus aureusin Pigs: A Randomized Controlled Trial, 10.1111/zph.12150
  686. Smith, Health and production management in beef feedlots. Herd health: food animal production medicine, 581 (2001)
  687. Smith Tara C., Gebreyes Wondwossen A., Abley Melanie J., Harper Abby L., Forshey Brett M., Male Michael J., Martin H. Wayne, Molla Bayleyegn Z., Sreevatsan Srinand, Thakur Siddhartha, Thiruvengadam Madhumathi, Davies Peter R., Methicillin-Resistant Staphylococcus aureus in Pigs and Farm Workers on Conventional and Antibiotic-Free Swine Farms in the USA, 10.1371/journal.pone.0063704
  688. Smith-Spangler Crystal, Brandeau Margaret L., Hunter Grace E., Bavinger J. Clay, Pearson Maren, Eschbach Paul J., Sundaram Vandana, Liu Hau, Schirmer Patricia, Stave Christopher, Olkin Ingram, Bravata Dena M., Are Organic Foods Safer or Healthier Than Conventional Alternatives? : A Systematic Review, 10.7326/0003-4819-157-5-201209040-00007
  689. Snyder Abigail B, Worobo Randy W, Chemical and genetic characterization of bacteriocins: antimicrobial peptides for food safety : Chemical and genetic characterization of bacteriocins, 10.1002/jsfa.6293
  690. Sommer Morten O.A., Church George M., Dantas Gautam, The human microbiome harbors a diverse reservoir of antibiotic resistance genes, 10.4161/viru.1.4.12010
  691. Song M., Liu Y., Soares J. A., Che T. M., Osuna O., Maddox C. W., Pettigrew J. E., Dietary clays alleviate diarrhea of weaned pigs, 10.2527/jas.2010-3662
  692. Song Juan, Li Ya li, Hu Cai hong, Effects of copper-exchanged montmorillonite, as alternative to antibiotic, on diarrhea, intestinal permeability and proinflammatory cytokine of weanling pigs, 10.1016/j.clay.2013.01.016
  693. Song Seong Kyu, Beck Bo Ram, Kim Daniel, Park John, Kim Jungjoon, Kim Hyun Duk, Ringø Einar, Prebiotics as immunostimulants in aquaculture: A review, 10.1016/j.fsi.2014.06.016
  694. Song Ze He, Xiao Kan, Ke Ya Lu, Jiao Le Fei, Hu Cai Hong, Zinc oxide influences mitogen-activated protein kinase and TGF-β1 signaling pathways, and enhances intestinal barrier integrity in weaned pigs, 10.1177/1753425914536450
  695. Sørensen, Acta Agric Scand (A), 50, 72 (2000)
  696. Sparbier K., Schubert S., Weller U., Boogen C., Kostrzewa M., Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry-Based Functional Assay for Rapid Detection of Resistance against  -Lactam Antibiotics, 10.1128/jcm.05737-11
  697. Speijers M.H.M., Baird L.G., Finney G.A., McBride J., Kilpatrick D.J., Logue D.N., O’Connell N.E., Effectiveness of different footbath solutions in the treatment of digital dermatitis in dairy cows, 10.3168/jds.2010-3468
  698. Speksnijder D. C., Jaarsma A. D. C., van der Gugten A. C., Verheij T. J. M., Wagenaar J. A., Determinants Associated with Veterinary Antimicrobial Prescribing in Farm Animals in the Netherlands: A Qualitative Study, 10.1111/zph.12168
  699. Speksnijder David C., Jaarsma Debbie A.C., Verheij Theo J.M., Wagenaar Jaap A., Attitudes and perceptions of Dutch veterinarians on their role in the reduction of antimicrobial use in farm animals, 10.1016/j.prevetmed.2015.08.014
  700. Speksnijder D. C., Mevius D. J., Bruschke C. J. M., Wagenaar J. A., Reduction of Veterinary Antimicrobial Use in the Netherlands. The Dutch Success Model, 10.1111/zph.12167
  701. Spillner Edzard, Braren Ingke, Greunke Kerstin, Seismann Henning, Blank Simon, du Plessis Dion, Avian IgY antibodies and their recombinant equivalents in research, diagnostics and therapy, 10.1016/j.biologicals.2012.05.003
  702. Spoolder Hans AM, Animal welfare in organic farming systems, 10.1002/jsfa.2999
  703. Spoolder Hans A. M., Waiblinger Susanne, Pigs and Humans, The Welfare of Pigs ISBN:9781402089084 p.211-236, 10.1007/978-1-4020-8909-1_7
  704. Spoolder Hans A.M., Aarnink André A.J., Vermeer Herman M., van Riel Johan, Edwards Sandra A., Effect of increasing temperature on space requirements of group housed finishing pigs, 10.1016/j.applanim.2012.02.010
  705. Ståhl K and Alenius S, 2012. BVDV control and eradication in Europe‐an update.
  706. Stefani Stefania, Chung Doo Ryeon, Lindsay Jodi A., Friedrich Alex W., Kearns Angela M., Westh Henrik, MacKenzie Fiona M., Meticillin-resistant Staphylococcus aureus (MRSA): global epidemiology and harmonisation of typing methods, 10.1016/j.ijantimicag.2011.09.030
  707. Fisher, Handbook of life stress cognition and health, 629 (1988)
  708. Stevens M., Piepers S., Supré K., Dewulf J., De Vliegher S., Quantification of antimicrobial consumption in adult cattle on dairy herds in Flanders, Belgium, and associations with udder health, milk quality, and production performance, 10.3168/jds.2015-10199
  709. Stojanov I, Milanov D, Dosen R, Marcic D, Prodanov‐Radulovic J, Pusic I and Polacek V, 2015. Swine Dysentery: Practical Observations, Control And Diagnostics.
  710. Stolker A.A.M., Manti V., Zuidema T., van Egmond H., Deckers E.R., Herbes R., Hooglugt J., Olde Heuvel E., de Jong J., Carry-over of veterinary drugs from medicated to non-medicated feeds in commercial feed manufacturing plants, 10.1080/19440049.2013.794308
  711. Stott Alistair W, Humphry Roger W, Gunn George J, Higgins Isabella, Hennessy Thia, O’Flaherty Joe, Graham David A, Predicted costs and benefits of eradicating BVDV from Ireland, 10.1186/2046-0481-65-12
  712. Subramaniam Mohana Devi, Kim In Ho, Clays as dietary supplements for swine: A review, 10.1186/s40104-015-0037-9
  713. Sundén F and Wullt B, 2015. Predictive value of urinary interleukin‐6 for symptomatic urinary tract infections in a nursing home population. International Journal of Urology.
  714. Susick E.K., Putnam M., Bermudez D.M., Thakur S., Longitudinal study comparing the dynamics of Clostridium difficile in conventional and antimicrobial free pigs at farm and slaughter, 10.1016/j.vetmic.2011.12.017
  715. Suthar Surindra, Chhimpa Vikram, Singh Sushma, Bacterial contamination in drinking water: a case study in rural areas of northern Rajasthan, India, 10.1007/s10661-008-0611-0
  716. Sutmoller Paul, Barteling Simon S, Olascoaga Raul Casas, Sumption Keith J, Control and eradication of foot-and-mouth disease, 10.1016/s0168-1702(02)00262-9
  717. SVA (National veterinary institute), 2009. Swedish veterinary antimicrobial resistance monitoring 2008. Available online: 0346‐2250
  718. SVA (National Veterinary Institute), 2010. Swedish Veterinary Antimicrobial Resistance Monitoring 2009. Available online:
  719. SVA (National Veterinary Institute), 2011. Swedish Veterinary Antimicrobial Resistance Monitoring 2010. Available online:
  720. SVA (National veterinary institute), 2015. Swedres‐Svarm 2014. Consumption of antibiotics and occurrence of antibiotic resistance in Sweden. Available at:
  721. SVA (National veterinary institute), 2016. Surveillance of infectious diseases in animals and humans in 2015. Available online:
  722. SVS, Svensk veterinärtidning, 42, 407 (1990)
  723. SVS (Swedish Veterinary Association), 2013. Riktlinjer för användning av antibiotika till produktionsdjur ‐ nötkreatur och gris. Available online:
  724. SVS (Swedish Veterinary Association), 2014. Riktlinjer för antibiotikaanvändning till får och get. Available online:
  725. SWAIN P, NAYAK S, NANDA P, DASH S, Biological effects of bacterial lipopolysaccharide (endotoxin) in fish: A review, 10.1016/j.fsi.2008.04.009
  726. Swann, Report of the joint committee on the use of antibiotics in animal husbandry and veterinary medicine (1969)
  727. Szulkin Robert, Whitington Thomas, Eklund Martin, Aly Markus, Eeles Rosalind A., Easton Douglas, Kote-Jarai ZSofia, Amin Al Olama Ali, Benlloch Sara, Muir Kenneth, Giles Graham G., Southey Melissa C., Fitzgerald Liesel M., Henderson Brian E., Schumacher Fredrick, Haiman Christopher A., Schleutker Johanna, Wahlfors Tiina, Tammela Teuvo LJ, Nordestgaard Børge G., Key Tim J., Travis Ruth C., Neal David E., Donovan Jenny L., Hamdy Freddie C., Pharoah Paul, Pashayan Nora, Khaw Kay-Tee, Stanford Janet L., Thibodeau Stephen N., McDonnell Shannon K., Schaid Daniel J., Maier Christiane, Vogel Walther, Luedeke Manuel, Herkommer Kathleen, Kibel Adam S., Cybulski Cezary, Lubiński Jan, Kluźniak Wojciech, Cannon-Albright Lisa, Brenner Hermann, Butterbach Katja, Stegmaier Christa, Park Jong Y., Sellers Thomas, Lim Hui-Yi, Slavov Chavdar, Kaneva Radka, Mitev Vanio, Batra Jyotsna, Clements Judith A., BioResource The Australian Prostate Cancer, Spurdle Amanda, Teixeira Manuel R., Paulo Paula, Maia Sofia, Pandha Hardev, Michael Agnieszka, Kierzek Andrzej, consortium the PRACTICAL, Gronberg Henrik, Wiklund Fredrik, Prediction of individual genetic risk to prostate cancer using a polygenic score : Polygenic Prostate Cancer Risk Score, 10.1002/pros.23037
  728. Tait J, Bruce A, Mittra J, Purves J and Scannell J, 2014. Independent review on antimicrobial resistance regulation/innovation interactions and the development of antimicrobial drugs and diagnostics for human and animal diseases: Main Report. 14th Dec., 2014. Available online:
  729. Tamang Migma Dorji, Gurung Mamata, Nam Hyang-Mi, Moon Dong Chan, Kim Su-Ran, Jang Geum-Chan, Jung Dae-Yeong, Jung Suk-Chan, Park Yong-Ho, Lim Suk-Kyung, Prevalence and characterization of Salmonella in pigs from conventional and organic farms and first report of S. serovar 1,4,[5],12:i:- from Korea, 10.1016/j.vetmic.2015.05.005
  730. Taverne FJ, , Jacobs JH, Heederik DJJ, Mouton JW, Wagenaar JA, van Geijlswijk IM, Influence of applying different units of measurement on reporting antimicrobial consumption data for pig farms, 10.1186/s12917-015-0566-7
  731. Taylor, Pig diseases (2013)
  732. Temtem Carolina, Kruse Amanda Brinch, Nielsen Liza Rosenbaum, Pedersen Ken Steen, Alban Lis, Comparison of the antimicrobial consumption in weaning pigs in Danish sow herds with different vaccine purchase patterns during 2013, 10.1186/s40813-016-0042-1
  733. ten Hooven, Pig Progress, 23, 24 (2007)
  734. Thomsen Birthe Lykke, Jorsal Sven Erik, Andersen Søren, Willeberg Preben, The cox regression model applied to risk factor analysis of infections in the breeding and multiplying herds in the Danish SPF system, 10.1016/0167-5877(92)90056-l
  735. Threlfall E. John, Antimicrobial drug resistance inSalmonella: problems and perspectives in food- and water-borne infections, 10.1111/j.1574-6976.2002.tb00606.x
  736. Tikofsky Linda L., Barlow John W., Santisteban Carlos, Schukken Ynte H., A Comparison of Antimicrobial Susceptibility Patterns forStaphylococcus aureusin Organic and Conventional Dairy Herds, 10.1089/107662903322541883
  737. Timbermont Leen, Lanckriet Anouk, Gholamiandehkordi Ahmad R., Pasmans Frank, Martel An, Haesebrouck Freddy, Ducatelle Richard, Van Immerseel Filip, Origin of Clostridium perfringens isolates determines the ability to induce necrotic enteritis in broilers, 10.1016/j.cimid.2008.07.001
  738. Timmerman Tom, Dewulf Jeroen, Catry Boudewijn, Feyen Bianca, Opsomer Geert, Kruif Aart de, Maes Dominiek, Quantification and evaluation of antimicrobial drug use in group treatments for fattening pigs in Belgium, 10.1016/j.prevetmed.2005.10.003
  739. Torrallardona David, Spray Dried Animal Plasma as an Alternative to Antibiotics in Weanling Pigs - A Review -, 10.5713/ajas.2010.70630
  740. Tosi Giovanni, Massi Paola, Antongiovanni Mauro, Buccioni Arianna, Minieri Sara, Marenchino Luigi, Mele Marcello, Efficacy Test of a Hydrolysable Tannin Extract Against Necrotic Enteritis in Challenged Broiler Chickens, 10.4081/ijas.2013.e62
  741. Toutain P.-L., Bousquet-Melou A., The consequences of generic marketing on antibiotic consumption and the spread of microbial resistance: the need for new antibiotics, 10.1111/jvp.12061
  742. Toutain Pierre-Louis, Ferran Aude A., Bousquet-Melou Alain, Pelligand Ludovic, Lees Peter, Veterinary Medicine Needs New Green Antimicrobial Drugs, 10.3389/fmicb.2016.01196
  743. Trckova, Veterinarni Medicina, 49, 389 (2004)
  744. Trckova, Veterinarni Medicina, 54, 47 (2009)
  745. Tremetsberger L, Winckler C, Effectiveness of animal health and welfare planning in dairy herds: a review, 10.7120/09627286.24.1.055
  746. Tuchscherer Margret, Puppe Birger, Tuchscherer Armin, Kanitz Ellen, Effects of social status after mixing on immune, metabolic, and endocrine responses in pigs, 10.1016/s0031-9384(98)00084-5
  747. Tummaruk, Journal of Applied Animal Science, 2, 23 (2009)
  748. Türkyılmaz S., Tekbıyık S., Oryasin E., Bozdogan B., Molecular Epidemiology and Antimicrobial Resistance Mechanisms of Methicillin-ResistantStaphylococcus aureusIsolated from Bovine Milk, 10.1111/j.1863-2378.2009.01257.x
  749. Turner S.P., Ewen M., Rooke J.A., Edwards S.A., The effect of space allowance on performance, aggression and immune competence of growing pigs housed on straw deep-litter at different group sizes, 10.1016/s0301-6226(00)00159-7
  750. Urban‐Chmiel, Journal of Livestock Science, 3, 27 (2012)
  751. Utiyama Carlos Eduardo, Oetting Liliana Lotufo, Giani Pedro Agostinho, Ruiz Urbano dos Santos, Miyada Valdomiro Shigueru, Efeitos de antimicrobianos, prebióticos, probióticos e extratos vegetais sobre a microbiota intestinal, a freqüência de diarréia e o desempenho de leitões recém-desmamados, 10.1590/s1516-35982006000800023
  752. Vaarst M., Bennedsgaard T.W., Klaas I., Nissen T.B., Thamsborg S.M., Østergaard S., Development and Daily Management of an Explicit Strategy of Nonuse of Antimicrobial Drugs in Twelve Danish Organic Dairy Herds, 10.3168/jds.s0022-0302(06)72253-6
  753. Vågsholm Ivar, Höjgård Sören, Antimicrobial sensitivity—A natural resource to be protected by a Pigouvian tax?, 10.1016/j.prevetmed.2010.05.003
  754. Vahjen Wilfried, Pietruszyńska Dominika, Starke Ingo C., Zentek Jürgen, High dietary zinc supplementation increases the occurrence of tetracycline and sulfonamide resistance genes in the intestine of weaned pigs, 10.1186/s13099-015-0071-3
  755. van Cleef Brigitte A.G.L., Monnet Dominique L., Voss Andreas, Krziwanek Karina, Allerberger Franz, Struelens Marc, Zemlickova Helena, Skov Robert L., Vuopio-Varkila Jaana, Cuny Christiane, Friedrich Alexander W., Spiliopoulou Iris, Pászti Judit, Hardardottir Hjordis, Rossney Angela, Pan Angelo, Pantosti Annalisa, Borg Michael, Grundmann Hajo, Mueller-Premru Manica, Olsson-Liljequist Barbro, Widmer Andreas, Harbarth Stephan, Schweiger Alexander, Unal Serhat, Kluytmans Jan A.J.W., Livestock-associated Methicillin-ResistantStaphylococcus aureus in Humans, Europe, 10.3201/eid1703.101036
  756. van de Ven L. J. F., van Wagenberg A. V., Groot Koerkamp P. W. G., Kemp B., van den Brand H., Effects of a combined hatching and brooding system on hatchability, chick weight, and mortality in broilers, 10.3382/ps.2009-00112
  757. Van de Ven GFA 2013. The use of autogenous vaccines in the Dutch pig industry and suggestions for new legislation of autogenous vaccines. Master thesis. Available online:
  758. van de Weerd Heleen A., Day Jon E.L., A review of environmental enrichment for pigs housed in intensive housing systems, 10.1016/j.applanim.2008.08.001
  759. van den Brand H., Wamsteeker D., Oostindjer M., van Enckevort L. C. M., van der Poel A. F. B., Kemp B., Bolhuis J. E., Effects of pellet diameter during and after lactation on feed intake of piglets pre- and postweaning, 10.2527/jas.2014-7408
  760. van der Horst Michael A., Schuurmans Jasper M., Smid Marja C., Koenders Belinda B., ter Kuile Benno H., De NovoAcquisition of Resistance to Three Antibiotics byEscherichia coli, 10.1089/mdr.2010.0101
  761. van der Mheen H and Spoolder HAM, 2003. Gently or roughly treated pigs. PraktijkRapport Varkens 19. Available online:
  762. van der Pol C. W., van Roovert-Reijrink I. A. M., Maatjens C. M., van den Brand H., Molenaar R., Effect of relative humidity during incubation at a set eggshell temperature and brooding temperature posthatch on embryonic mortality and chick quality, 10.3382/ps.2013-03006
  763. van Dixhoorn Ingrid D. E., Reimert Inonge, Middelkoop Jenny, Bolhuis J. Elizabeth, Wisselink Henk J., Groot Koerkamp Peter W. G., Kemp Bas, Stockhofe-Zurwieden Norbert, Enriched Housing Reduces Disease Susceptibility to Co-Infection with Porcine Reproductive and Respiratory Virus (PRRSV) and Actinobacillus pleuropneumoniae (A. pleuropneumoniae) in Young Pigs, 10.1371/journal.pone.0161832
  764. van Hoek Angela H.A.M., Stalenhoef Janneke E., van Duijkeren Engeline, Franz Eelco, Comparative virulotyping of extended-spectrum cephalosporin-resistant E. coli isolated from broilers, humans on broiler farms and in the general population and UTI patients, 10.1016/j.vetmic.2016.04.008
  765. Alternative systems for poultry: health, welfare and productivity, ISBN:9781845938246, 10.1079/9781845938246.0000
  766. VAN IMMERSEEL F., METHNER U., RYCHLIK I., NAGY B., VELGE P., MARTIN G., FOSTER N., DUCATELLE R., BARROW P. A., Vaccination and early protection against non-host-specific Salmonella serotypes in poultry: exploitation of innate immunity and microbial activity, 10.1017/s0950268805004711
  767. Van Loo Ellen J., Alali Walid, Ricke Steven C., Food Safety and Organic Meats, 10.1146/annurev-food-022811-101158
  768. Veterinary Pharmacology and Toxicology, ISBN:9789400966062, 10.1007/978-94-009-6604-8
  769. van Rennings Lisa, von Münchhausen Christiane, Ottilie Henry, Hartmann Maria, Merle Roswitha, Honscha Walther, Käsbohrer Annemarie, Kreienbrock Lothar, Cross-Sectional Study on Antibiotic Usage in Pigs in Germany, 10.1371/journal.pone.0119114
  770. van Schaik G., Dijkhuizen A. A., Benedictus G., Barkema H. W., Koole J. L., Exploratory study on the economic value of a closed farming system on Dutch dairy farms, 10.1136/vr.142.10.240
  771. Varela Norma P., Gadbois Pierre, Thibault Claude, Gottschalk Marcelo, Dick Paul, Wilson Jeff, Antimicrobial resistance and prudent drug use for Streptococcus suis, 10.1017/s1466252313000029
  772. Vega C., Bok M., Saif L., Fernandez F., Parreño V., Egg yolk IgY antibodies: A therapeutic intervention against group A rotavirus in calves, 10.1016/j.rvsc.2015.09.005
  773. Vidanarachchi, Animal Production Science, 53, 1247 (2013)
  774. Vieira Antonio R., Collignon Peter, Aarestrup Frank M., McEwen Scott A., Hendriksen Rene S., Hald Tine, Wegener Henrik C., Association Between Antimicrobial Resistance inEscherichia coliIsolates from Food Animals and Blood Stream Isolates from Humans in Europe: An Ecological Study, 10.1089/fpd.2011.0950
  775. VIEIRA A. R., PIRES S. M., HOUE H., EMBORG H.-D., Trends in slaughter pig production and antimicrobial consumption in Danish slaughter pig herds, 2002–2008, 10.1017/s0950268810002724
  776. Vigre Håkan, Dohoo Ian R., Stryhn Henrik, Jensen Vibeke Frøkjær, Use of register data to assess the association between use of antimicrobials and outbreak of Postweaning Multisystemic Wasting Syndrome (PMWS) in Danish pig herds, 10.1016/j.prevetmed.2009.10.010
  777. Vinod M.G., Shivu M.M., Umesha K.R., Rajeeva B.C., Krohne G., Karunasagar Indrani, Karunasagar Iddya, Isolation of Vibrio harveyi bacteriophage with a potential for biocontrol of luminous vibriosis in hatchery environments, 10.1016/j.aquaculture.2005.12.003
  778. Visschers V.H.M., Backhans A., Collineau L., Iten D., Loesken S., Postma M., Belloc C., Dewulf J., Emanuelson U., Beilage E. grosse, Siegrist M., Sjölund M., Stärk K.D.C., Perceptions of antimicrobial usage, antimicrobial resistance and policy measures to reduce antimicrobial usage in convenient samples of Belgian, French, German, Swedish and Swiss pig farmers, 10.1016/j.prevetmed.2015.01.018
  779. Viswanathan M, Berkman ND, Dryden DM and Hartling L, 2013. Assessing risk of bias and confounding in observational studies of interventions or exposures: Further Development of the RTI item bank. AHRQ Publication No. 13‐EHC106‐EF. Agency for Healthcare Research and Quality (US), Rockville, MD. Available at:
  780. VMD (Veterinary Medicines Directorate), 2015. UK‐VARSS 2014 – UK veterinary antibiotic resistance and sales surveillance report. Available online:
  781. VOSE D.J., ACAR J., ANTHONY F., FRANKLIN A., GUPTA R., NICHOLLS T.J., TAMURA Y., THOMPSON S., THRELFALL E.J., VAN VUUREN M., WHITE D.G., WEGENER H.C., COSTARRICA M.L., Antimicrobial resistance: risk analysis methodology for the potential impact on public health of antimicrobial resistant bacteria of animal origin : -EN- -FR- -ES-, 10.20506/rst.20.3.1319
  782. Voss Andreas, Loeffen Frans, Bakker Judith, Klaassen Corne, Wulf Mireille, Methicillin-resistantStaphylococcus aureusin Pig Farming, 10.3201/eid1112.050428
  783. Vuong, International Journal of Probiotics & Prebiotics, 11, 1 (2016)
  784. Waghu Faiza Hanif, Barai Ram Shankar, Gurung Pratima, Idicula-Thomas Susan, CAMPR3: a database on sequences, structures and signatures of antimicrobial peptides: Table 1., 10.1093/nar/gkv1051
  785. Waiblinger S, Menke C, Coleman G, The relationship between attitudes, personal characteristics and behaviour of stockpeople and subsequent behaviour and production of dairy cows, 10.1016/s0168-1591(02)00155-7
  786. Wainwright M, Maisch T, Nonell S, Plaetzer K, Almeida A, Tegos GP and Hamblin MR, 2016. Photoantimicrobials‐are we afraid of the light? The Lancet Infectious Diseases, online ahead of print.
  787. Wales Andrew, Davies Robert, Co-Selection of Resistance to Antibiotics, Biocides and Heavy Metals, and Its Relevance to Foodborne Pathogens, 10.3390/antibiotics4040567
  788. Walk S. T., Mladonicky J. M., Middleton J. A., Heidt A. J., Cunningham J. R., Bartlett P., Sato K., Whittam T. S., Influence of Antibiotic Selection on Genetic Composition of Escherichia coli Populations from Conventional and Organic Dairy Farms, 10.1128/aem.00709-07
  789. Wasyl Dariusz, Kern-Zdanowicz Izabela, Domańska-Blicharz Katarzyna, Zając Magdalena, Hoszowski Andrzej, High-level fluoroquinolone resistant Salmonella enterica serovar Kentucky ST198 epidemic clone with IncA/C conjugative plasmid carrying blaCTX-M-25 gene, 10.1016/j.vetmic.2014.10.014
  790. Weese J. S., Hannon S. J., Booker C. W., Gow S., Avery B. P., Reid-Smith R. J., The Prevalence of Methicillin-Resistant Staphylococcus aureus Colonization in Feedlot Cattle : Prevalence of Methicillin-Resistant S. aureus, 10.1111/j.1863-2378.2011.01428.x
  791. Wegener Henrik C., Hald Tine, Wong Danilo Lo Fo, Madsen Mogens, Korsgaard Helle, Bager Flemming, Gerner-Smidt Peter, Mølbak Kåre, SalmonellaControl Programs in Denmark, 10.3201/eid0907.030024
  792. Welfare Quality® consortium , 2009. Welfare Quality® Assessment Protocol for Cattle, 2009, ISBN/EAN 978‐90‐78240‐04‐4. 180 pp.
  793. Wellington Elizabeth MH, Boxall Alistair BA, Cross Paul, Feil Edward J, Gaze William H, Hawkey Peter M, Johnson-Rollings Ashley S, Jones Davey L, Lee Nicholas M, Otten Wilfred, Thomas Christopher M, Williams A Prysor, The role of the natural environment in the emergence of antibiotic resistance in Gram-negative bacteria, 10.1016/s1473-3099(12)70317-1
  794. Wenk, In: Antimicrobial Growth Promoters: Where do we go from here?, 329 (2006)
  795. Westphal A., Williams M. L., Baysal-Gurel F., LeJeune J. T., McSpadden Gardener B. B., General Suppression of Escherichia coli O157:H7 in Sand-Based Dairy Livestock Bedding, 10.1128/aem.01655-10
  796. WHITE D.G., ACAR J., ANTHONY F., FRANKLIN A., GUPTA R., NICHOLLS T.J., TAMURA Y., THOMPSON S., THRELFALL E.J., VOSE D.J., VAN VUUREN M., WEGENER H.C., COSTARRICA M.L., Antimicrobial resistance: standardisation and harmonisation of laboratory methodologies for the detection and quantification of antimicrobial resistance : -EN- -FR- -ES-, 10.20506/rst.20.3.1316
  797. Whitworth Kristin M, Rowland Raymond R R, Ewen Catherine L, Trible Benjamin R, Kerrigan Maureen A, Cino-Ozuna Ada G, Samuel Melissa S, Lightner Jonathan E, McLaren David G, Mileham Alan J, Wells Kevin D, Prather Randall S, Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus, 10.1038/nbt.3434
  798. WHO (World Health Organization), 1990. Guide to an SPF‐swine programme. Available online:
  799. WHO (World Health Organization), 2003. Impacts of antimicrobial growth promoter termination in Denmark: the WHO international review panel's evaluation of the termination of the use of antimicrobial growth promoters in Denmark: Foulum, Denmark 6–9 November 2002. Available online:
  800. WHO (World Health Organization), 2011. Tackling antibiotic resistance from a food safety perspective in Europe. Available online: 9289014210
  801. WHO (World Health Organisation), 2012. Critically important antimicrobials for human medicine ‐ 3rd revision 2011. Available online:
  802. WHO (World Health Organization), 2015. Global action plan on antimicrobial resistance. Available online:
  803. WHO FAO and OIE (World Health Organization, Food and Agriculture Organization, World Organisation for Animal Health), 2016. Antimicrobial resistance: a manual for developing national action plans. Available online:
  804. Wideman R. F., Al-Rubaye A., Kwon Y. M., Blankenship J., Lester H., Mitchell K. N., Pevzner I. Y., Lohrmann T., Schleifer J., Prophylactic administration of a combined prebiotic and probiotic, or therapeutic administration of enrofloxacin, to reduce the incidence of bacterial chondronecrosis with osteomyelitis in broilers, 10.3382/ps/peu025
  805. Wielinga Peter R., Jensen Vibeke F., Aarestrup Frank M., Schlundt Jørgen, Evidence-based policy for controlling antimicrobial resistance in the food chain in Denmark, 10.1016/j.foodcont.2013.11.047
  806. Wierup Martin, The Swedish Experience of the 1986 Year Ban of Antimicrobial Growth Promoters, with Special Reference to Animal Health, Disease Prevention, Productivity, and Usage of Antimicrobials, 10.1089/10766290152045066
  807. Norrgren, Ecology and Animal Health, 203 (2012)
  808. Wilhelm Barbara, Rajić Andrijana, Waddell Lisa, Parker Sarah, Harris Janet, Roberts Karen C., Kydd Robyn, Greig Judy, Baynton Ashley, Prevalence of Zoonotic or Potentially Zoonotic Bacteria, Antimicrobial Resistance, and Somatic Cell Counts in Organic Dairy Production: Current Knowledge and Research Gaps, 10.1089/fpd.2008.0181
  809. Willeberg, Acta Veterinaria Scandinavica, 90, 25 (1996)
  810. Wilson RL, Holyoake PK, Cronin GM, Doyle RE, Managing animal wellbeing: a preliminary survey of pig farmers, 10.1111/avj.12169
  811. Windisch W and Kroismayr A, 2006. The effects of phytobiotics on performance and gut function in monogastrics. Proceedings of the World nutrition forum: The future of animal nutrition, 85–90.
  812. Wiuff C, Lykkesfeldt J, Svendsen O, Aarestrup F.M, The effects of oral and intramuscular administration and dose escalation of enrofloxacin on the selection of quinolone resistance among Salmonella and coliforms in pigs, 10.1016/s0034-5288(03)00112-7
  813. Xavier B, Lammens C, Ruhal R, Kumar‐Singh S, Butaye P, Goossens H and Malhotra‐Kumar S, 2016. Identification of mcr‐2 in colistin‐resistant E. coli isolates not harbouring mcr‐1. Eurosurveillance, 21, pii=30280.
  814. Xu Yongping, Li Xiaoyu, Jin Liji, Zhen Yuhong, Lu Yanan, Li Shuying, You Jiansong, Wang Linhui, Application of chicken egg yolk immunoglobulins in the control of terrestrial and aquatic animal diseases: A review, 10.1016/j.biotechadv.2011.07.003
  815. YANG Y., IJI P.A., CHOCT M., Dietary modulation of gut microflora in broiler chickens: a review of the role of six kinds of alternatives to in-feed antibiotics, 10.1017/s0043933909000087
  816. Yegani, World Poultry, 21, 18 (2005)
  817. Youn S. Y., Kwon Y. K., Song C. S., Lee H. J., Jeong O. M., Choi B. K., Jung S. C., Kang M. S., Increased efficacy of inactivated vaccine candidates prepared withSalmonella entericaserovar Typhimurium strains of predominant genotypes in ducks, 10.3382/ps/pew104
  818. Young B. A., Cold Stress as it Affects Animal Production, 10.2527/jas1981.521154x
  819. Young C.W., Eidman V.R., Reneau J.K., Animal Health and Management and Their Impact on Economic Efficiency, 10.3168/jds.s0022-0302(85)80998-x
  820. YOUNG I., RAJIĆ A., WILHELM B. J., WADDELL L., PARKER S., McEWEN S. A., Comparison of the prevalence of bacterial enteropathogens, potentially zoonotic bacteria and bacterial resistance to antimicrobials in organic and conventional poultry, swine and beef production: a systematic review and meta-analysis, 10.1017/s0950268809002635
  821. Yount NY and Yeaman MR, 2012. Emerging themes and therapeutic prospects for anti‐infective peptides. 52, 337–360.
  822. Zankari E., Hasman H., Kaas R. S., Seyfarth A. M., Agerso Y., Lund O., Larsen M. V., Aarestrup F. M., Genotyping using whole-genome sequencing is a realistic alternative to surveillance based on phenotypic antimicrobial susceptibility testing, 10.1093/jac/dks496
  823. Zhang Dexian, Li Rui, Li Jichang, Lactobacillus reuteri ATCC 55730 and L22 display probiotic potential in vitro and protect against Salmonella-induced pullorum disease in a chick model of infection, 10.1016/j.rvsc.2011.06.020
  824. Zhang L., Huang Y., Zhou Y., Buckley T., Wang H. H., Antibiotic Administration Routes Significantly Influence the Levels of Antibiotic Resistance in Gut Microbiota, 10.1128/aac.00670-13
  825. Zhang Jiancheng, Li Zhen, Cao Zhenhui, Wang Lili, Li Xiaoyu, Li Shuying, Xu Yongping, Bacteriophages as antimicrobial agents against major pathogens in swine: a review, 10.1186/s40104-015-0039-7
  826. Zhao, PLoS ONE, 8, 1 (2013)
  827. Zhuang Q., Barfod K., Wachmann H., Mortensen S., Lavritsen D. T., Ydesen B., Willeberg P., Risk factors for Actinobacillus pleuropneumoniae serotype 2 infection in Danish genetic specific pathogen-free pig herds, 10.1136/vr.160.8.258
  828. Zulkifli I, Siti Nor Azah A, Fear and stress reactions, and the performance of commercial broiler chickens subjected to regular pleasant and unpleasant contacts with human being, 10.1016/j.applanim.2004.02.014
  829. Zwonitzer Martha R., Soupir Michelle L., Jarboe Laura R., Smith Douglas R., Quantifying Attachment and Antibiotic Resistance of from Conventional and Organic Swine Manure, 10.2134/jeq2015.05.0245