User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach

Primary tabs

download
  • Open access
  • PDF
  • 493.57 K
Adel, Adel [Institute of Veterinary Sciences, University Saad Dahlab, Blida, Algeria] Abatih, Emmanuel [Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, Antwerpen, Belgium] Speybroeck, Niko [UCL] Soukehal, Abdelkrim [University Hospital of Beni Messous, Algiers, Algeria] Bouguedour, Rachid [OIE Sub-Regional Representation for North Africa, 17 Avenue d’Afrique, El Menzah V 2091, Tunis, Tunesia] Berkvens, Dirk [Institute of Tropical Medicine, Department of Biomedical Sciences, Nationalestraat 155, Antwerpen, Belgium]

A large-scale study on canine Leishmania infection (CanL) was conducted in six localities along a west-east transect in the Algerian littoral zone (Tlemcen, Mostaganem, Tipaza, Boumerdes, Bejaia, Jijel) and covering two sampling periods. In total 2,184 dogs were tested with an indirect fluorescent antibody test (IFAT) and a direct agglutination test (DAT). Combined multiple-testing and several statistical methods were compared to estimate the CanL true prevalence and tests characteristics (sensitivity and specificity). The Bayesian full model showed the best fit and yielded prevalence estimates between 11% (Mostaganem, first period) and 38% (Bejaia, second period). Sensitivity of IFAT varied (in function of locality) between 86% and 88% while its specificity varied between 65% and 87%. DAT was less sensitive than IFAT but showed a higher specificity (between 80% and 95% in function of locality or/and season). A general increasing trend of the CanL prevalence was noted from west to east. A concordance between the present results and the incidence of human cases of visceral leishmaniasis was observed, where also a maximum was recorded for Bejaia. The results of the present study highlight the dangers when using IFAT as a gold standard.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 2015
Language Anglais
Journal information "PLoS One" - Vol. 10, p. e0117313 (2015)
Peer reviewed yes
Publisher Public Library of Science
issn 1932-6203
e-issn 1932-6203
Affiliation UCL - SSS/IRSS - Institut de recherche santé et société
Links
  1. Alvar Jorge, Cañavate Carmen, Molina Ricardo, Moreno Javier, Nieto Javier, Canine Leishmaniasis, Advances in Parasitology Volume 57 (2004) ISBN:9780120317578 p.1-88, 10.1016/s0065-308x(04)57001-x
  2. Moreno Javier, Alvar Jorge, Canine leishmaniasis: epidemiological risk and the experimental model, 10.1016/s1471-4922(02)02347-4
  3. KILLICK-KENDRICK R., Phlebotomine vectors of the leishmaniases: a review, 10.1111/j.1365-2915.1990.tb00255.x
  4. Izri M. A., Belazzoug S., Boudjebla Y., Dereure J., Pratlong S., Delalbre-Belmonte A., Rioux J.-A., Leishmania infantumMon-1 isole dePhlebotomus perniciosus, en Kabylie (Algerie), 10.1051/parasite/1990653151
  5. Oliva G., Scalone A., Foglia Manzillo V., Gramiccia M., Pagano A., Di Muccio T., Gradoni L., Incidence and Time Course of Leishmania infantum Infections Examined by Parasitological, Serologic, and Nested-PCR Techniques in a Cohort of Naive Dogs Exposed to Three Consecutive Transmission Seasons, 10.1128/jcm.44.4.1318-1322.2006
  6. Killick-Kendrick R., Killick-Kendrick M., Tang Y., Anthroponotic cutaneous leishmaniasis in Kabul, Afghanistan: the high susceptibility of Phlebotomus sergenti to Leishmania tropica, 10.1016/0035-9203(95)90072-1
  7. Alvar J., Molina R., San Andrés M., Tesouro M., Nieto J., Vitutia M., González F., San Andrés M. D., Boggio J., Rodriguez F., Sáinz A., Escacena C., Canine leishmaniasis: clinical, parasitological and entomological follow-up after chemotherapy, 10.1080/00034983.1994.11812879
  8. Molina R., Amela C., Nieto J., San-Andrés M., González F., Castillo J.A., Lucientes J., Alvar J., Infectivity of dogs naturally infected with Leishmania infantum to colonized Phlebotomus perniciosus, 10.1016/0035-9203(94)90446-4
  9. Scalone A, De Luna R, Oliva G, Baldi L, Satta G, Vesco G, Mignone W, Turilli C, Mondesire R.R, Simpson D, Donoghue A.R, Frank G.R, Gradoni L, Evaluation of the Leishmania recombinant K39 antigen as a diagnostic marker for canine leishmaniasis and validation of a standardized enzyme-linked immunosorbent assay, 10.1016/s0304-4017(01)00643-4
  10. Gomes Aparecida H.S., Armelin Izabel M., Menon Sueli Z., Pereira-Chioccola Vera L., Leishmania (V.) braziliensis: Detection by PCR in biopsies from patients with cutaneous leishmaniasis, 10.1016/j.exppara.2008.02.014
  11. OIE (2014). Leishmaniosis. URL http://www.oie.int/fileadmin/Home/eng/Health_standards/tahm/2.01.08_LEISHMANIOSIS.pdf
  12. Adel Amel, Saegerman Claude, Speybroeck Niko, Praet Nicolas, Victor Bjorn, De Deken Redgi, Soukehal Abdelkrim, Berkvens Dirk, Canine leishmaniasis in Algeria: True prevalence and diagnostic test characteristics in groups of dogs of different functional type, 10.1016/j.vetpar.2010.05.009
  13. K Addadi, Bulletin de la Société de Pathologie Exotique, 69, 68 (1976)
  14. S Belazzoug, Annales de la Société Belge de Médecine Tropicale, 65, 329 (1985)
  15. Z Harrat, Bulletin de la Société de Pathologie Exotique, 85, 296 (1992)
  16. Adel Amel, Boughoufalah Amel, Saegerman Claude, De Deken Redgi, Bouchene Zahida, Soukehal Abdelkrim, Berkvens Dirk, Boelaert Marleen, Epidemiology of Visceral Leishmaniasis in Algeria: An Update, 10.1371/journal.pone.0099207
  17. Bertrand Philippe, Bénichou Jacques, Grenier Philippe, Chastang Claude, Hui and Walter's latent-class reference-free approach may be more useful in assessing agreement than diagnostic performance, 10.1016/j.jclinepi.2004.10.021
  18. I Dohoo (2003)
  19. Collins John, Huynh Minh, Estimation of diagnostic test accuracy without full verification: a review of latent class methods, 10.1002/sim.6218
  20. Hui S. L., Walter S. D., Estimating the Error Rates of Diagnostic Tests, 10.2307/2530508
  21. Dendukuri Nandini, Joseph Lawrence, Bayesian Approaches to Modeling the Conditional Dependence Between Multiple Diagnostic Tests, 10.1111/j.0006-341x.2001.00158.x
  22. Vercammen F., De Deken R., Antibody kinetics during allopurinol treatment in canine leishmaniasis, 10.1136/vr.139.11.264-a
  23. F Mancianti, American Journal of Veterinary Research, 49, 1409 (1988)
  24. P Abranches, Annales de Parasitologie Humaine et Comparée, 58, 307 (1983)
  25. Abranches P., Silva-Pereira M. C. D., Conceicao-Silva F. M., Santos-Gomes G. M., Janz J. G., Canine Leishmaniasis: Pathological and Ecological Factors Influencing Transmission of Infection, 10.2307/3283159
  26. A El Harith, Journal of Clinical Microbiology, 27, 2252 (1989)
  27. BOELAERT M., AOUN K., LIINEV J., GOETGHEBEUR E., VAN DER STUYFT P., The potential of Latent Class Analysis in diagnostic test validation for canine Leishmania infantum infection, 10.1017/s0950268899003040
  28. Cicchetti Domenic V., Feinstein Alvan R., High agreement but low kappa: II. Resolving the paradoxes, 10.1016/0895-4356(90)90159-m
  29. Graham Patrick, Bull Brian, Approximate Standard Errors and Confidence Intervals for Indices of Positive and Negative Agreement, 10.1016/s0895-4356(98)00048-1
  30. Berkvens Dirk, Speybroeck Niko, Praet Nicolas, Adel Amel, Lesaffre Emmanuel, Estimating Disease Prevalence in a Bayesian Framework Using Probabilistic Constraints : , 10.1097/01.ede.0000198422.64801.8d
  31. D Spiegelhalter (2003)
  32. ROGAN WALTER J., GLADEN BETH, ESTIMATING PREVALENCE FROM THE RESULTS OF A SCREENING TEST, 10.1093/oxfordjournals.aje.a112510
  33. M Diouani, Archives de L’institut Pasteur Tunis, 85, 55 (2008)
  34. Zoghlami Z, Chouihi E, Barhoumi W, Dachraoui K, Massoudi N, et al. (2014) Interaction between canine and human visceral leishmaniases in a holoendemic focus of central Tunisia.
  35. Nejjar R., Lemrani M., Malki A., Ibrahimy S., Amarouch H., Benslimane A., Canine leishmaniasis due toLeishmania infantumMON-1 in northern Morocco, 10.1051/parasite/1998054325
  36. M Rami, Parasite, 10, 79 (2003)
  37. Morillas F., Rabasco F. Sanchez, Ocaña J., Martin-Sanchez J., Ocaña-Wihelmi J., Acedo C., Sanchiz-Marin M. C., Leishmaniosis in the focus of the Axarquía region, Malaga province, southern Spain: a survey of the human, dog, and vector, 10.1007/s004360050164
  38. Zaffaroni Enrico, Rubaudo Lara, Lanfranchi Paolo, Mignone Walter, Epidemiological patterns of canine leishmaniosis in Western Liguria (Italy), 10.1016/s0304-4017(98)00237-4
  39. Ntais Pantelis, Antoniou Maria, Poupalos George, Christodoulou Vasiliki, Sifaki-Pistola Dimitra, Pratlong Francine, Messaritakis Ippokratis, Leishmaniases in Greece, 10.4269/ajtmh.13-0070
  40. Schallig Henk DFH, Cardoso Luís, Semião-Santos Saul J, Seroepidemiology of canine leishmaniosis in Évora (southern Portugal): 20-year trends, 10.1186/1756-3305-6-100
  41. Neogy Asit B., Rzepka Didier, Tselentis Yiannis, Lascombe Jean C., Vouldoukis Ioannis, Silva Otamires A., Monjour Loic, Segalen Thierry, Serodiagnosis and Screening of Canine Visceral Leishmaniasis in an Endemic Area of Corsica: Applicability of a Direct Agglutination Test and Immunoblot Analysis, 10.4269/ajtmh.1992.47.772
  42. Ertabaklar Hatice, Ozensoy Toz Seray, Taylan Ozkan Aysegul, Rastgeldi Samiye, Balcioglu I. Cuneyt, Ozbel Yusuf, Serological and entomological survey in a zoonotic visceral leishmaniasis focus of North Central Anatolia, Turkey: Corum province, 10.1016/j.actatropica.2005.01.002
  43. Chaouch Melek, Mhadhbi Moez, Adams Emily R., Schoone Gerard J., Limam Sassi, Gharbi Zyneb, Darghouth Mohamed Aziz, Guizani Ikram, BenAbderrazak Souha, Development and evaluation of a loop-mediated isothermal amplification assay for rapid detection of Leishmania infantum in canine leishmaniasis based on cysteine protease B genes, 10.1016/j.vetpar.2013.07.038
  44. L Iniesta, Clinical and Diagnostic Laboratory Immunology, 9, 1137 (2002)
  45. Ballart Cristina, Alcover M Magdalena, Picado Albert, Nieto Javier, Castillejo Soledad, Portús Montserrat, Gállego Montserrat, First survey on canine leishmaniasis in a non classical area of the disease in Spain (Lleida, Catalonia) based on a veterinary questionnaire and a cross-sectional study, 10.1016/j.prevetmed.2012.09.003
  46. Sousa Susana, Lopes Ana Patricia, Cardoso Luís, Silvestre Ricardo, Schallig Henk, Reed Steven G., Cordeiro da Silva Anabela, Seroepidemiological survey of Leishmania infantum infection in dogs from northeastern Portugal, 10.1016/j.actatropica.2011.06.003
  47. Enøe Claes, Georgiadis Marios P, Johnson Wesley O, Estimation of sensitivity and specificity of diagnostic tests and disease prevalence when the true disease state is unknown, 10.1016/s0167-5877(00)00117-3
  48. Dendukuri Nandini, Hadgu Alula, Wang Liangliang, Modeling conditional dependence between diagnostic tests: A multiple latent variable model, 10.1002/sim.3470
  49. Lesaffre Emmanuel, Speybroeck Niko, Berkvens Dirk, Bayes and diagnostic testing, 10.1016/j.vetpar.2007.05.010
  50. Gardner Ian A, Stryhn Henrik, Lind Peter, Collins Michael T, Conditional dependence between tests affects the diagnosis and surveillance of animal diseases, 10.1016/s0167-5877(00)00119-7
  51. Rodriguez-Cortes A., Ojeda A., Francino O., Lopez-Fuertes L., Timon M., Alberola J., Leishmania Infection: Laboratory Diagnosing in the Absence of a "Gold Standard", 10.4269/ajtmh.2010.09-0366
  52. Rodríguez-Cortés Alhelí, Ojeda Ana, Todolí Felicitat, Alberola Jordi, Performance of commercially available serological diagnostic tests to detect Leishmania infantum infection on experimentally infected dogs, 10.1016/j.vetpar.2012.09.009
  53. Maia C., Campino L., Methods for diagnosis of canine leishmaniasis and immune response to infection, 10.1016/j.vetpar.2008.07.028
  54. Fernández-Bellon H., Solano-Gallego L., Rodríguez-Cortés A., Ferrer L., Gallego M., Alberola J., Ramis A., Little evidence of seasonal variation of natural infection by Leishmania infantum in dogs in Spain, 10.1016/j.vetpar.2008.04.009
  55. Acedo-Sánchez C, Morillas-Márquez F, Sanchı́z-Marı́n M.C, Martı́n-Sánchez J, Changes in antibody titres against Leishmania infantum in naturally infected dogs in southern Spain, 10.1016/s0304-4017(97)00196-9
Bibliographic reference Adel, Adel ; Abatih, Emmanuel ; Speybroeck, Niko ; Soukehal, Abdelkrim ; Bouguedour, Rachid ; et. al. Estimation of canine Leishmania infection prevalence in six cities of the Algerian littoral zone using a Bayesian approach. In: PLoS One, Vol. 10, p. e0117313 (2015)
Permanent URL http://hdl.handle.net/2078.1/162084