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Probiotics, prebiotics, and the host microbiome: the science of translation

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Petschow, Bryon Doré, Joël Hibberd, Patricia Dinan, Timothy Reid, Gregor Cani, Patrice D. [UCL] Sanders, Mary Ellen

Recent advances in our understanding of the community structure and function of the human microbiome have implications for the potential role of probiotics and prebiotics in promoting human health. A group of experts recently met to review the latest advances in microbiota/microbiome research and discuss the implications for development of probiotics and prebiotics, primarily as they relate to effects mediated via the intestine. The goals of the meeting were to share recent advances in research on the microbiota, microbiome, probiotics, and prebiotics, and to discuss these findings in the contexts of regulatory barriers, evolving healthcare environments, and potential effects on a variety of health topics, including the development of obesity and diabetes; the long-term consequences of exposure to antibiotics early in life to the gastrointestinal (GI) microbiota; lactose intolerance; and the relationship between the GI microbiota and the central nervous system, with implications for depression, cognition, satiety, and mental health for people living in developed and developing countries. This report provides an overview of these discussions.

Document type Article de périodique (Journal article) – Synthèse de littérature
Access type Accès restreint
Publication date 2013
Language Anglais
Journal information "Annals / New York Academy of Sciences" - Vol. 1306, no.Annals Reports, p. 1-17 (2013)
Peer reviewed yes
Publisher Wiley-Blackwell Publishing, Inc. ((United States) Malden, MA )
issn 0077-8923
e-issn 1749-6632
Publication status Publié
Affiliation UCL - SSS/LDRI - Louvain Drug Research Institute
MESH Subject Cognition ; Obesity ; Prebiotics ; Probiotics ; Translational Medical Research ; Congresses as Topic ; Depression ; Diabetes Mellitus ; Humans ; Intestines ; Lactose Intolerance ; Mental Health ; Microbiota
Links
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Bibliographic reference Petschow, Bryon ; Doré, Joël ; Hibberd, Patricia ; Dinan, Timothy ; Reid, Gregor ; et. al. Probiotics, prebiotics, and the host microbiome: the science of translation. In: Annals / New York Academy of Sciences, Vol. 1306, no.Annals Reports, p. 1-17 (2013)
Permanent URL http://hdl.handle.net/2078.1/146421