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Telmisartan, ramipril, or both in patients at high risk for vascular events.

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Yusuf, Salim Teo, Koon K Pogue, Janice Dyal, Leanne Laloux, Patrice [UCL]

Telmisartan was equivalent to ramipril in patients with vascular disease or high-risk diabetes and was associated with less angioedema. The combination of the two drugs was associated with more adverse events without an increase in benefit. (ClinicalTrials.gov number, NCT00153101 [ClinicalTrials.gov].).

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2008
Language Anglais
Journal information "New England Journal of Medicine" - Vol. 358, no.15, p. 1547-59 (2008)
Peer reviewed yes
Publisher Massachusetts Medical Society ((United States) [S.l.])
issn 0028-4793
e-issn 1533-4406
Publication status Publié
Affiliations UCL - (MGD) Service de neurologie
UCL - MD/NOPS - Département de neurologie et de psychiatrie
MESH Subject Aged ; Diabetes Mellitus ; Double-Blind Method ; Drug Therapy, Combination ; Female ; Follow-Up Studies ; Hospitalization ; Humans ; Kaplan-Meier Estimate ; Male ; Middle Aged ; Angioedema ; Ramipril ; Risk ; Angiotensin II Type 1 Receptor Blockers ; Angiotensin-Converting Enzyme Inhibitors ; Benzimidazoles ; Benzoates ; Blood Pressure ; Cardiovascular Diseases ; Creatinine
Links
Bibliographic reference ; Yusuf, Salim ; Teo, Koon K ; Pogue, Janice ; Dyal, Leanne ; et. al. Telmisartan, ramipril, or both in patients at high risk for vascular events.. In: New England Journal of Medicine, Vol. 358, no.15, p. 1547-59 (2008)
Permanent URL http://hdl.handle.net/2078.1/132619