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Shaping the nervous system: role of the core planar cell polarity genes.

Bibliographic reference Tissir, Fadel ; Goffinet, André. Shaping the nervous system: role of the core planar cell polarity genes.. In: Nature Reviews Neuroscience, Vol. 14, p. 525–535 (2013)
Permanent URL http://hdl.handle.net/2078.1/130050
  1. Ambegaonkar Abhijit A., Pan Guohui, Mani Madhav, Feng Yongqiang, Irvine Kenneth D., Propagation of Dachsous-Fat Planar Cell Polarity, 10.1016/j.cub.2012.05.049
  2. Brittle Amy, Thomas Chloe, Strutt David, Planar Polarity Specification through Asymmetric Subcellular Localization of Fat and Dachsous, 10.1016/j.cub.2012.03.053
  3. Vinson Charles R., Adler Paul N., Directional non-cell autonomy and the transmission of polarity information by the frizzled gene of Drosophila, 10.1038/329549a0
  4. Krasnow R. E., Development, 121, 4095 (1995)
  5. Taylor J., Genetics, 150, 199 (1998)
  6. Chae J., Development, 126, 5421 (1999)
  7. Usui Tadao, Shima Yasuyuki, Shimada Yuko, Hirano Shinji, Burgess Robert W, Schwarz Thomas L, Takeichi Masatoshi, Uemura Tadashi, Flamingo, a Seven-Pass Transmembrane Cadherin, Regulates Planar Cell Polarity under the Control of Frizzled, 10.1016/s0092-8674(00)80046-x
  8. Feiguin Fabian, Hannus Michael, Mlodzik Marek, Eaton Suzanne, The Ankyrin Repeat Protein Diego Mediates Frizzled-Dependent Planar Polarization, 10.1016/s1534-5807(01)00010-7
  9. Wolff T., Development, 125, 1149 (1998)
  10. Shimada Yuko, Yonemura Shigenobu, Ohkura Hiroyuki, Strutt David, Uemura Tadashi, Polarized Transport of Frizzled along the Planar Microtubule Arrays in Drosophila Wing Epithelium, 10.1016/j.devcel.2005.11.016
  11. Guo Yusong, Zanetti Giulia, Schekman Randy, A novel GTP-binding protein–adaptor protein complex responsible for export of Vangl2 from the trans Golgi network, 10.7554/elife.00160
  12. Giese A. P., Ezan J., Wang L., Lasvaux L., Lembo F., Mazzocco C., Richard E., Reboul J., Borg J.-P., Kelley M. W., Sans N., Brigande J., Montcouquiol M., Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear, 10.1242/dev.074229
  13. Das G., Diego interacts with Prickle and Strabismus/Van Gogh to localize planar cell polarity complexes, 10.1242/dev.01317
  14. Adler Paul N., Planar Signaling and Morphogenesis in Drosophila, 10.1016/s1534-5807(02)00176-4
  15. Goodrich L. V., Strutt D., Principles of planar polarity in animal development, 10.1242/dev.054080
  16. Klein Thomas J., Mlodzik Marek, PLANAR CELL POLARIZATION: An Emerging Model Points in the Right Direction, 10.1146/annurev.cellbio.21.012704.132806
  17. Lawrence Peter A., Struhl Gary, Casal José, Planar cell polarity: one or two pathways?, 10.1038/nrg2125
  18. Tissir Fadel, Goffinet André M, Planar cell polarity signaling in neural development, 10.1016/j.conb.2010.05.006
  19. Wallingford John B., Planar Cell Polarity and the Developmental Control of Cell Behavior in Vertebrate Embryos, 10.1146/annurev-cellbio-092910-154208
  20. Eaton Suzanne, Jülicher Frank, Cell flow and tissue polarity patterns, 10.1016/j.gde.2011.08.010
  21. Vichas Athea, Zallen Jennifer A., Translating cell polarity into tissue elongation, 10.1016/j.semcdb.2011.09.013
  22. Strutt David I., Weber Ursula, Mlodzik Marek, The role of RhoA in tissue polarity and Frizzled signalling, 10.1038/387292a0
  23. Lu Bingwei, Usui Tadao, Uemura Tadashi, Jan Lily, Jan Yuh-Nung, Flamingo controls the planar polarity of sensory bristles and asymmetric division of sensory organ precursors in Drosophila, 10.1016/s0960-9822(99)80505-3
  24. Schweisguth François, Bellaïche Yohanns, Gho Michel, Kaltschmidt Julia A., Brand Andrea H., 10.1038/35050558
  25. Gray Ryan S., Roszko Isabelle, Solnica-Krezel Lilianna, Planar Cell Polarity: Coordinating Morphogenetic Cell Behaviors with Embryonic Polarity, 10.1016/j.devcel.2011.06.011
  26. Ezan Jérôme, Montcouquiol Mireille, Revisiting planar cell polarity in the inner ear, 10.1016/j.semcdb.2013.03.012
  27. Devenport Danelle, Fuchs Elaine, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles, 10.1038/ncb1784
  28. Devenport Danelle, Oristian Daniel, Heller Evan, Fuchs Elaine, Mitotic internalization of planar cell polarity proteins preserves tissue polarity, 10.1038/ncb2284
  29. Guo N., Hawkins C., Nathans J., From The Cover: Frizzled6 controls hair patterning in mice, 10.1073/pnas.0402802101
  30. Ravni Aurélia, Qu Yibo, Goffinet André M., Tissir Fadel, Planar Cell Polarity Cadherin Celsr1 Regulates Skin Hair Patterning in the Mouse, 10.1038/jid.2009.84
  31. Chang H., Nathans J., Responses of hair follicle-associated structures to loss of planar cell polarity signaling, 10.1073/pnas.1301430110
  32. Wang Y., Nathans J., Tissue/planar cell polarity in vertebrates: new insights and new questions, 10.1242/dev.02772
  33. Gao Fen-Biao, Kohwi Minoree, Brenman Jay E., Jan Lily Yeh, Jan Yuh Nung, Control of Dendritic Field Formation in Drosophila, 10.1016/s0896-6273(00)00088-x
  34. Senti Kirsten-André, Usui Tadao, Boucke Karin, Greber Urs, Uemura Tadashi, Dickson Barry J., Flamingo Regulates R8 Axon-Axon and Axon-Target Interactions in the Drosophila Visual System, 10.1016/s0960-9822(03)00291-4
  35. Fenstermaker A. G., Prasad A. A., Bechara A., Adolfs Y., Tissir F., Goffinet A., Zou Y., Pasterkamp R. J., Wnt/Planar Cell Polarity Signaling Controls the Anterior-Posterior Organization of Monoaminergic Axons in the Brainstem, 10.1523/jneurosci.4508-10.2010
  36. Tissir F., Nature Neurosci., 8, 451 (2005)
  37. Wang Y., J. Neurosci., 22, 8563 (2002)
  38. Bingham Stephanie, Higashijima Shin-ichi, Okamoto Hitoshi, Chandrasekhar Anand, The Zebrafish trilobite Gene Is Essential for Tangential Migration of Branchiomotor Neurons, 10.1006/dbio.2001.0532
  39. Jessen J. R., Nature Cell Biol., 4, 610 (2002)
  40. Rohrschneider Monica R., Elsen Gina E., Prince Victoria E., Zebrafish Hoxb1a regulates multiple downstream genes including prickle1b, 10.1016/j.ydbio.2007.06.012
  41. Carreira-Barbosa F., Prickle 1 regulates cell movements during gastrulation and neuronal migration in zebrafish, 10.1242/dev.00567
  42. Wada H., Tanaka H., Nakayama S., Iwasaki M., Okamoto H., Frizzled3a and Celsr2 function in the neuroepithelium to regulate migration of facial motor neurons in the developing zebrafish hindbrain, 10.1242/dev.02665
  43. Qu Y., Glasco D. M., Zhou L., Sawant A., Ravni A., Fritzsch B., Damrau C., Murdoch J. N., Evans S., Pfaff S. L., Formstone C., Goffinet A. M., Chandrasekhar A., Tissir F., Atypical Cadherins Celsr1-3 Differentially Regulate Migration of Facial Branchiomotor Neurons in Mice, 10.1523/jneurosci.0124-10.2010
  44. Vivancos Valerie, Chen Ping, Spassky Nathalie, Qian Dong, Dabdoub Alain, Kelley Matthew, Studer Michele, Guthrie Sarah, Wnt activity guides facial branchiomotor neuron migration, and involves the PCP pathway and JNK and ROCK kinases, 10.1186/1749-8104-4-7
  45. Glasco Derrick M., Sittaramane Vinoth, Bryant Whitney, Fritzsch Bernd, Sawant Anagha, Paudyal Anju, Stewart Michelle, Andre Philipp, Cadete Vilhais-Neto Gonçalo, Yang Yingzi, Song Mi-Ryoung, Murdoch Jennifer N., Chandrasekhar Anand, The mouse Wnt/PCP protein Vangl2 is necessary for migration of facial branchiomotor neurons, and functions independently of Dishevelled, 10.1016/j.ydbio.2012.06.021
  46. Greene Nicholas D. E., Copp Andrew J., Development of the vertebrate central nervous system: formation of the neural tube, 10.1002/pd.2206
  47. Wang J., Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation, 10.1242/dev.02347
  48. Ybot-Gonzalez P., Savery D., Gerrelli D., Signore M., Mitchell C. E., Faux C. H., Greene N. D. E., Copp A. J., Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure, 10.1242/dev.000380
  49. Heisenberg Carl-Philipp, Tada Masazumi, Rauch Gerd-Jörg, Saúde Leonor, Concha Miguel L., Geisler Robert, Stemple Derek L., Smith James C., Wilson Stephen W., Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation, 10.1038/35011068
  50. Tada M., Development, 127, 2227 (2000)
  51. Wallingford John B., Rowning Brian A., Vogeli Kevin M., Rothbächer Ute, Fraser Scott E., Harland Richard M., Dishevelled controls cell polarity during Xenopus gastrulation, 10.1038/35011077
  52. Wallingford J. B., Neural tube closure requires Dishevelled-dependent convergent extension of the midline, 10.1242/dev.00123
  53. Kibar Zoha, Vogan Kyle J., Groulx Normand, Justice Monica J., Underhill D. Alan, Gros Philippe, 10.1038/90081
  54. Wang Y., The Role of Frizzled3 and Frizzled6 in Neural Tube Closure and in the Planar Polarity of Inner-Ear Sensory Hair Cells, 10.1523/jneurosci.4698-05.2005
  55. Lee Jianyi, Andreeva Anna, Sipe Conor W., Liu Lixia, Cheng Amy, Lu Xiaowei, PTK7 Regulates Myosin II Activity to Orient Planar Polarity in the Mammalian Auditory Epithelium, 10.1016/j.cub.2012.03.068
  56. Lu Xiaowei, Borchers Annette G. M., Jolicoeur Christine, Rayburn Helen, Baker Julie C., Tessier-Lavigne Marc, PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates, 10.1038/nature02677
  57. Hamblet N. S., Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure, 10.1242/dev.00164
  58. Curtin John A., Quint Elizabeth, Tsipouri Vicky, Arkell Ruth M., Cattanach Bruce, Copp Andrew J., Henderson Deborah J., Spurr Nigel, Stanier Philip, Fisher Elizabeth M., Nolan Patrick M., Steel Karen P., Brown Steve D.M., Gray Ian C., Murdoch Jennifer N., Mutation of Celsr1 Disrupts Planar Polarity of Inner Ear Hair Cells and Causes Severe Neural Tube Defects in the Mouse, 10.1016/s0960-9822(03)00374-9
  59. Murdoch J. N., Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification, 10.1093/hmg/10.22.2593
  60. Juriloff Diana M., Harris Muriel J., A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects, 10.1002/bdra.23079
  61. Allache Redouane, De Marco Patrizia, Merello Elisa, Capra Valeria, Kibar Zoha, Role of the planar cell polarity gene CELSR1 in neural tube defects and caudal agenesis, 10.1002/bdra.23002
  62. Doudney K., Moore G.E., Stanier P., Ybot-Gonzalez P., Paternotte C., Greene N.D.E., Copp A.J., Stevenson R.E., Analysis of the planar cell polarity geneVangl2and its co-expressed paralogueVangl1in neural tube defect patients, 10.1002/ajmg.a.30766
  63. Robinson Alexis, Escuin Sarah, Doudney Kit, Vekemans Michel, Stevenson Roger E., Greene Nicholas D.E., Copp Andrew J., Stanier Philip, Mutations in the planar cell polarity genesCELSR1andSCRIBare associated with the severe neural tube defect craniorachischisis, 10.1002/humu.21662
  64. Kibar Zoha, Torban Elena, McDearmid Jonathan R., Reynolds Annie, Berghout Joanne, Mathieu Melissa, Kirillova Irena, De Marco Patrizia, Merello Elisa, Hayes Julie M., Wallingford John B., Drapeau Pierre, Capra Valeria, Gros Philippe, Mutations inVANGL1Associated with Neural-Tube Defects, 10.1056/nejmoa060651
  65. Bosoi Ciprian M., Capra Valeria, Allache Redouane, Trinh Vincent Quoc-Huy, De Marco Patrizia, Merello Elisa, Drapeau Pierre, Bassuk Alexander G., Kibar Zoha, Identification and characterization of novel rare mutations in the planar cell polarity genePRICKLE1in human neural tube defects, 10.1002/humu.21589
  66. De Marco Patrizia, Merello Elisa, Rossi Andrea, Piatelli Gianluca, Cama Armando, Kibar Zoha, Capra Valeria, FZD6is a novel gene for human neural tube defects, 10.1002/humu.21643
  67. Ciruna Brian, Jenny Andreas, Lee Diana, Mlodzik Marek, Schier Alexander F., Planar cell polarity signalling couples cell division and morphogenesis during neurulation, 10.1038/nature04375
  68. Nishimura Tamako, Honda Hisao, Takeichi Masatoshi, Planar Cell Polarity Links Axes of Spatial Dynamics in Neural-Tube Closure, 10.1016/j.cell.2012.04.021
  69. Merte Janna, Jensen Devon, Wright Kevin, Sarsfield Sarah, Wang Yanshu, Schekman Randy, Ginty David D., Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure, 10.1038/ncb2002
  70. Wansleeben C., Feitsma H., Montcouquiol M., Kroon C., Cuppen E., Meijlink F., Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b, 10.1242/dev.041434
  71. Segalen Marion, Bellaïche Yohanns, Cell division orientation and planar cell polarity pathways, 10.1016/j.semcdb.2009.03.018
  72. Gong Ying, Mo Chunhui, Fraser Scott E., Planar cell polarity signalling controls cell division orientation during zebrafish gastrulation, 10.1038/nature02796
  73. Ségalen Marion, Johnston Christopher A., Martin Charlotte A., Dumortier Julien G., Prehoda Kenneth E., David Nicolas B., Doe Chris Q., Bellaïche Yohanns, The Fz-Dsh Planar Cell Polarity Pathway Induces Oriented Cell Division via Mud/NuMA in Drosophila and Zebrafish, 10.1016/j.devcel.2010.10.004
  74. Lake Blue B., Sokol Sergei Y., Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain, 10.1083/jcb.200807073
  75. Wallingford J. B., Mitchell B., Strange as it may seem: the many links between Wnt signaling, planar cell polarity, and cilia, 10.1101/gad.2008011
  76. Eley Lorraine, Yates Laura M, Goodship Judith A, Cilia and disease, 10.1016/j.gde.2005.04.008
  77. Davenport J. R., An incredible decade for the primary cilium: a look at a once-forgotten organelle, 10.1152/ajprenal.00118.2005
  78. Song Hai, Hu Jianxin, Chen Wen, Elliott Gene, Andre Philipp, Gao Bo, Yang Yingzi, Planar cell polarity breaks bilateral symmetry by controlling ciliary positioning, 10.1038/nature09129
  79. Marshall Wallace F, Kintner Christopher, Cilia orientation and the fluid mechanics of development, 10.1016/j.ceb.2007.11.009
  80. Wallingford John B, Planar cell polarity signaling, cilia and polarized ciliary beating, 10.1016/j.ceb.2010.07.011
  81. Voronina Vera A., Takemaru Ken-Ichi, Treuting Piper, Love Damon, Grubb Barbara R., Hajjar Adeline M., Adams Allison, Li Feng-Qian, Moon Randall T., Inactivation of Chibby affects function of motile airway cilia, 10.1083/jcb.200809144
  82. Tissir Fadel, Qu Yibo, Montcouquiol Mireille, Zhou Libing, Komatsu Kouji, Shi Dongbo, Fujimori Toshihiko, Labeau Jason, Tyteca Donatienne, Courtoy Pierre, Poumay Yves, Uemura Tadashi, Goffinet Andre M, Lack of cadherins Celsr2 and Celsr3 impairs ependymal ciliogenesis, leading to fatal hydrocephalus, 10.1038/nn.2555
  83. Guirao Boris, Meunier Alice, Mortaud Stéphane, Aguilar Andrea, Corsi Jean-Marc, Strehl Laetitia, Hirota Yuki, Desoeuvre Angélique, Boutin Camille, Han Young-Goo, Mirzadeh Zaman, Cremer Harold, Montcouquiol Mireille, Sawamoto Kazunobu, Spassky Nathalie, Coupling between hydrodynamic forces and planar cell polarity orients mammalian motile cilia, 10.1038/ncb2040
  84. Mitchell Brian, Jacobs Richard, Li Julie, Chien Shu, Kintner Chris, A positive feedback mechanism governs the polarity and motion of motile cilia, 10.1038/nature05771
  85. Mirzadeh Z., Han Y.-G., Soriano-Navarro M., Garcia-Verdugo J. M., Alvarez-Buylla A., Cilia Organize Ependymal Planar Polarity, 10.1523/jneurosci.3744-09.2010
  86. Park Tae Joo, Haigo Saori L, Wallingford John B, Ciliogenesis defects in embryos lacking inturned or fuzzy function are associated with failure of planar cell polarity and Hedgehog signaling, 10.1038/ng1753
  87. Park Tae Joo, Mitchell Brian J, Abitua Philip B, Kintner Chris, Wallingford John B, Dishevelled controls apical docking and planar polarization of basal bodies in ciliated epithelial cells, 10.1038/ng.104
  88. Mitchell Brian, Stubbs Jennifer L., Huisman Fawn, Taborek Peter, Yu Clare, Kintner Chris, The PCP Pathway Instructs the Planar Orientation of Ciliated Cells in the Xenopus Larval Skin, 10.1016/j.cub.2009.04.018
  89. Vladar Eszter K., Bayly Roy D., Sangoram Ashvin M., Scott Matthew P., Axelrod Jeffrey D., Microtubules Enable the Planar Cell Polarity of Airway Cilia, 10.1016/j.cub.2012.09.046
  90. Kunimoto Koshi, Yamazaki Yuji, Nishida Tomoki, Shinohara Kyosuke, Ishikawa Hiroaki, Hasegawa Toshiaki, Okanoue Takeshi, Hamada Hiroshi, Noda Tetsuo, Tamura Atsushi, Tsukita Shoichiro, Tsukita Sachiko, Coordinated Ciliary Beating Requires Odf2-Mediated Polarization of Basal Bodies via Basal Feet, 10.1016/j.cell.2011.10.052
  91. Werner Michael E., Hwang Peter, Huisman Fawn, Taborek Peter, Yu Clare C., Mitchell Brian J., Actin and microtubules drive differential aspects of planar cell polarity in multiciliated cells, 10.1083/jcb.201106110
  92. Adler Paul N., The frizzled/stan Pathway and Planar Cell Polarity in the Drosophila Wing, Planar Cell Polarity During Development (2012) ISBN:9780123945921 p.1-31, 10.1016/b978-0-12-394592-1.00001-6
  93. Gault William J., Olguin Patricio, Weber Ursula, Mlodzik Marek, DrosophilaCK1-γ,gilgamesh, controls PCP-mediated morphogenesis through regulation of vesicle trafficking, 10.1083/jcb.201107137
  94. Sepich D. S., Usmani M., Pawlicki S., Solnica-Krezel L., Wnt/PCP signaling controls intracellular position of MTOCs during gastrulation convergence and extension movements, 10.1242/dev.053959
  95. Babayeva S., Zilber Y., Torban E., Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes, 10.1152/ajprenal.00566.2009
  96. Habas Raymond, Kato Yoichi, He Xi, Wnt/Frizzled Activation of Rho Regulates Vertebrate Gastrulation and Requires a Novel Formin Homology Protein Daam1, 10.1016/s0092-8674(01)00614-6
  97. Hirota Y., Meunier A., Huang S., Shimozawa T., Yamada O., Kida Y. S., Inoue M., Ito T., Kato H., Sakaguchi M., Sunabori T., Nakaya M.-a., Nonaka S., Ogura T., Higuchi H., Okano H., Spassky N., Sawamoto K., Planar polarity of multiciliated ependymal cells involves the anterior migration of basal bodies regulated by non-muscle myosin II, 10.1242/dev.050120
  98. Axelrod J. D., Miller J. R., Shulman J. M., Moon R. T., Perrimon N., Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways, 10.1101/gad.12.16.2610
  99. Yasunaga Takayuki, Itoh Keiji, Sokol Sergei Y., Regulation of basal body and ciliary functions by Diversin, 10.1016/j.mod.2011.07.004
  100. Ross Alison J, May-Simera Helen, Eichers Erica R, Kai Masatake, Hill Josephine, Jagger Daniel J, Leitch Carmen C, Chapple J Paul, Munro Peter M, Fisher Shannon, Tan Perciliz L, Phillips Helen M, Leroux Michel R, Henderson Deborah J, Murdoch Jennifer N, Copp Andrew J, Eliot Marie-Madeleine, Lupski James R, Kemp David T, Dollfus Hélène, Tada Masazumi, Katsanis Nicholas, Forge Andrew, Beales Philip L, Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates, 10.1038/ng1644
  101. Olguín Patricio, Glavic Alvaro, Mlodzik Marek, Intertissue Mechanical Stress Affects Frizzled-Mediated Planar Cell Polarity in the Drosophila Notum Epidermis, 10.1016/j.cub.2011.01.001
  102. Aigouy Benoît, Farhadifar Reza, Staple Douglas B., Sagner Andreas, Röper Jens-Christian, Jülicher Frank, Eaton Suzanne, Cell Flow Reorients the Axis of Planar Polarity in the Wing Epithelium of Drosophila, 10.1016/j.cell.2010.07.042
  103. Banizs B., Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus, 10.1242/dev.02153
  104. Ibañez-Tallon Inés, Pagenstecher Axel, Fliegauf Manfred, Olbrich Heike, Kispert Andreas, Ketelsen Uwe-Peter, North Alison, Heintz Nathaniel, Omran Heymut, Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation , 10.1093/hmg/ddh219
  105. Lechtreck Karl-Ferdinand, Delmotte Philippe, Robinson Michael L., Sanderson Michael J., Witman George B., Mutations inHydinimpair ciliary motility in mice, 10.1083/jcb.200710162
  106. Town T., Breunig J. J., Sarkisian M. R., Spilianakis C., Ayoub A. E., Liu X., Ferrandino A. F., Gallagher A. R., Li M. O., Rakic P., Flavell R. A., The stumpy gene is required for mammalian ciliogenesis, 10.1073/pnas.0712385105
  107. Ibanez-Tallon I., To beat or not to beat: roles of cilia in development and disease, 10.1093/hmg/ddg061
  108. Chandrasekhar Anand, Turning heads: Development of vertebrate branchiomotor neurons, 10.1002/dvdy.10444
  109. Garel S., Development, 127, 5297 (2000)
  110. Guthrie Sarah, Patterning and axon guidance of cranial motor neurons, 10.1038/nrn2254
  111. Song M.-R., Shirasaki R., Cai C.-L., Ruiz E. C., Evans S. M., Lee S.-K., Pfaff S. L., T-Box transcription factor Tbx20 regulates a genetic program for cranial motor neuron cell body migration, 10.1242/dev.02694
  112. Goffinet A. M., J. Anat., 138, 207 (1984)
  113. Gilland Edwin, Baker Robert, Evolutionary Patterns of Cranial Nerve Efferent Nuclei in Vertebrates, 10.1159/000088128
  114. Walsh G. S., Grant P. K., Morgan J. A., Moens C. B., Planar polarity pathway and Nance-Horan syndrome-like 1b have essential cell-autonomous functions in neuronal migration, 10.1242/dev.063842
  115. Mapp Oni M., Wanner Sarah J., Rohrschneider Monica R., Prince Victoria E., Prickle1b mediates interpretation of migratory cues during zebrafish facial branchiomotor neuron migration, 10.1002/dvdy.22283
  116. Formstone Caroline J., 7TM-Cadherins: Developmental Roles and Future Challenges, Advances in Experimental Medicine and Biology (2010) ISBN:9781441979124 p.14-36, 10.1007/978-1-4419-7913-1_2
  117. Ying G., Wu S., Hou R., Huang W., Capecchi M. R., Wu Q., The Protocadherin Gene Celsr3 Is Required for Interneuron Migration in the Mouse Forebrain, 10.1128/mcb.00011-09
  118. Stockinger P., Maitre J.-L., Heisenberg C.-P., Defective neuroepithelial cell cohesion affects tangential branchiomotor neuron migration in the zebrafish neural tube, 10.1242/dev.071233
  119. Wanner S. J., Prince V. E., Axon tracts guide zebrafish facial branchiomotor neuron migration through the hindbrain, 10.1242/dev.087148
  120. Formstone Caroline J., Moxon Christopher, Murdoch Jennifer, Little Peter, Mason Ivor, Basal enrichment within neuroepithelia suggests novel function(s) for Celsr1 protein, 10.1016/j.mcn.2010.03.008
  121. Reuter J. E., A mosaic genetic screen for genes necessary for Drosophila mushroom body neuronal morphogenesis, 10.1242/dev.00319
  122. Kimura H., Potential dual molecular interaction of the Drosophila 7-pass transmembrane cadherin Flamingo in dendritic morphogenesis, 10.1242/jcs.02832
  123. Matsubara D., Horiuchi S.-y., Shimono K., Usui T., Uemura T., The seven-pass transmembrane cadherin Flamingo controls dendritic self-avoidance via its binding to a LIM domain protein, Espinas, in Drosophila sensory neurons, 10.1101/gad.16531611
  124. Shima Yasuyuki, Kengaku Mineko, Hirano Tomoo, Takeichi Masatoshi, Uemura Tadashi, Regulation of Dendritic Maintenance and Growth by a Mammalian 7-Pass Transmembrane Cadherin, 10.1016/j.devcel.2004.07.007
  125. Shima Yasuyuki, Kawaguchi Shin-ya, Kosaka Kazuyoshi, Nakayama Manabu, Hoshino Mikio, Nabeshima Yoichi, Hirano Tomoo, Uemura Tadashi, Opposing roles in neurite growth control by two seven-pass transmembrane cadherins, 10.1038/nn1933
  126. Chen Pei-Ling, Clandinin Thomas R., The Cadherin Flamingo Mediates Level-Dependent Interactions that Guide Photoreceptor Target Choice in Drosophila, 10.1016/j.neuron.2008.01.007
  127. Lee Roger C, Clandinin Thomas R, Lee Chi-Hon, Chen Pei-Ling, Meinertzhagen Ian A, Zipursky S Lawrence, The protocadherin Flamingo is required for axon target selection in the Drosophila visual system, 10.1038/nn1063
  128. Hakeda-Suzuki Satoko, Berger-Müller Sandra, Tomasi Tatiana, Usui Tadao, Horiuchi Shin-ya, Uemura Tadashi, Suzuki Takashi, Golden Goal collaborates with Flamingo in conferring synaptic-layer specificity in the visual system, 10.1038/nn.2756
  129. Mrkusich Eli M., Flanagan Dustin J., Whitington Paul M., The core planar cell polarity gene prickle interacts with flamingo to promote sensory axon advance in the Drosophila embryo, 10.1016/j.ydbio.2011.07.032
  130. Shimizu K., Sato M., Tabata T., The Wnt5/Planar Cell Polarity Pathway Regulates Axonal Development of the Drosophila Mushroom Body Neuron, 10.1523/jneurosci.0154-11.2011
  131. Ng J., Wnt/PCP proteins regulate stereotyped axon branch extension in Drosophila, 10.1242/dev.068668
  132. Steimel A., Wong L., Najarro E. H., Ackley B. D., Garriga G., Hutter H., The Flamingo ortholog FMI-1 controls pioneer-dependent navigation of follower axons in C. elegans, 10.1242/dev.054320
  133. Huarcaya Najarro Elvis, Ackley Brian D., C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons, 10.1016/j.ydbio.2013.01.014
  134. Najarro E. H., Wong L., Zhen M., Carpio E. P., Goncharov A., Garriga G., Lundquist E. A., Jin Y., Ackley B. D., Caenorhabditis elegans Flamingo Cadherin fmi-1 Regulates GABAergic Neuronal Development, 10.1523/jneurosci.3094-11.2012
  135. Bassuk Alexander G., Wallace Robyn H., Buhr Aimee, Buller Andrew R., Afawi Zaid, Shimojo Masahito, Miyata Shingo, Chen Shan, Gonzalez-Alegre Pedro, Griesbach Hilary L., Wu Shu, Nashelsky Marcus, Vladar Eszter K., Antic Dragana, Ferguson Polly J., Cirak Sebahattin, Voit Thomas, Scott Matthew P., Axelrod Jeffrey D., Gurnett Christina, Daoud Azhar S., Kivity Sara, Neufeld Miriam Y., Mazarib Aziz, Straussberg Rachel, Walid Simri, Korczyn Amos D., Slusarski Diane C., Berkovic Samuel F., El-Shanti Hatem I., A Homozygous Mutation in Human PRICKLE1 Causes an Autosomal-Recessive Progressive Myoclonus Epilepsy-Ataxia Syndrome, 10.1016/j.ajhg.2008.10.003
  136. Fujimura Lisa, Hatano Masahiko, Role of Prickle1 and Prickle2 in Neurite Outgrowth in Murine Neuroblastoma Cells, Methods in Molecular Biology (2012) ISBN:9781617795091 p.173-185, 10.1007/978-1-61779-510-7_14
  137. Okuda Hiroaki, Miyata Shingo, Mori Yasutake, Tohyama Masaya, MousePrickle1andPrickle2are expressed in postmitotic neurons and promote neurite outgrowth, 10.1016/j.febslet.2007.08.075
  138. Hida Y., Fukaya M., Hagiwara A., Deguchi-Tawarada M., Yoshioka T., Kitajima I., Inoue E., Watanabe M., Ohtsuka T., Prickle2 is localized in the postsynaptic density and interacts with PSD-95 and NMDA receptors in the brain, 10.1093/jb/mvr023
  139. Yoshioka Toshinori, Hagiwara Akari, Hida Yamato, Ohtsuka Toshihisa, Vangl2, the planner cell polarity protein, is complexed with postsynaptic density protein PSD-95, 10.1016/j.febslet.2013.03.030
  140. Feng J., Xu Y., Wang M., Ruan Y., So K.-F., Tissir F., Goffinet A., Zhou L., A Role for Atypical Cadherin Celsr3 in Hippocampal Maturation and Connectivity, 10.1523/jneurosci.1965-12.2012
  141. Price David J., Kennedy Henry, Dehay Colette, Zhou Libing, Mercier Marjorie, Jossin Yves, Goffinet André M., Tissir Fadel, Blakey Daniel, Molnár Zoltán, The development of cortical connections, 10.1111/j.1460-9568.2006.04620.x
  142. Lyuksyutova A. I., Anterior-Posterior Guidance of Commissural Axons by Wnt-Frizzled Signaling, 10.1126/science.1089610
  143. Shafer Beth, Onishi Keisuke, Lo Charles, Colakoglu Gulsen, Zou Yimin, Vangl2 Promotes Wnt/Planar Cell Polarity-like Signaling by Antagonizing Dvl1-Mediated Feedback Inhibition in Growth Cone Guidance, 10.1016/j.devcel.2011.01.002
  144. Zhou L., Bar I., Achouri Y., Campbell K., De Backer O., Hebert J. M., Jones K., Kessaris N., de Rouvroit C. L., O'Leary D., Richardson W. D., Goffinet A. M., Tissir F., Early Forebrain Wiring: Genetic Dissection Using Conditional Celsr3 Mutant Mice, 10.1126/science.1155244
  145. Steinel Martin C., Whitington Paul M., The atypical cadherin Flamingo is required for sensory axon advance beyond intermediate target cells, 10.1016/j.ydbio.2008.12.026
  146. Sasselli Valentina, Boesmans Werend, Vanden Berghe Pieter, Tissir Fadel, Goffinet André M., Pachnis Vassilis, Planar cell polarity genes control the connectivity of enteric neurons, 10.1172/jci66759
  147. Xu Qiang, Wang Yanshu, Dabdoub Alain, Smallwood Philip M, Williams John, Woods Chad, Kelley Matthew W, Jiang Li, Tasman William, Zhang Kang, Nathans Jeremy, Vascular Development in the Retina and Inner Ear, 10.1016/s0092-8674(04)00216-8
  148. Greco Valentina, Hannus Michael, Eaton Suzanne, Argosomes, 10.1016/s0092-8674(01)00484-6
  149. Février Benoit, Raposo Graça, Exosomes: endosomal-derived vesicles shipping extracellular messages, 10.1016/j.ceb.2004.06.003
  150. Sagner Andreas, Merkel Matthias, Aigouy Benoit, Gaebel Julia, Brankatschk Marko, Jülicher Frank, Eaton Suzanne, Establishment of Global Patterns of Planar Polarity during Growth of the Drosophila Wing Epithelium, 10.1016/j.cub.2012.04.066
  151. Heberlein Ulrike, Wolff Tanya, Rubin Gerald M., The TGFβ homolog dpp and the segment polarity gene hedgehog are required for propagation of a morphogenetic wave in the Drosophila retina, 10.1016/0092-8674(93)90535-x
  152. Pourquié Olivier, Vertebrate Segmentation: From Cyclic Gene Networks to Scoliosis, 10.1016/j.cell.2011.05.011
  153. Bosveld F., Bonnet I., Guirao B., Tlili S., Wang Z., Petitalot A., Marchand R., Bardet P.-L., Marcq P., Graner F., Bellaiche Y., Mechanical Control of Morphogenesis by Fat/Dachsous/Four-Jointed Planar Cell Polarity Pathway, 10.1126/science.1221071
  154. Wang Y., Chang H., Nathans J., When whorls collide: the development of hair patterns in frizzled 6 mutant mice, 10.1242/dev.057455
  155. Casal J., Lawrence P. A., Struhl G., Two separate molecular systems, Dachsous/Fat and Starry night/Frizzled, act independently to confer planar cell polarity, 10.1242/dev.02641
  156. Lawrence Peter A., Struhl Gary, Casal José, Do the protocadherins Fat and Dachsous link up to determine both planar cell polarity and the dimensions of organs?, 10.1038/ncb1208-1379
  157. Amonlirdviman K., Mathematical Modeling of Planar Cell Polarity to Understand Domineering Nonautonomy, 10.1126/science.1105471
  158. Formstone C.J., Little P.F.R., The flamingo-related mouse Celsr family (Celsr1–3) genes exhibit distinct patterns of expression during embryonic development, 10.1016/s0925-4773(01)00515-9
  159. Shima Yasuyuki, Copeland Neal G., Gilbert Debra J., Jenkins Nancy A., Chisaka Osamu, Takeichi Masatoshi, Uemura Tadashi, Differential expression of the seven-pass transmembrane cadherin genesCelsr1-3 and distribution of the Celsr2 protein during mouse development, 10.1002/dvdy.10054
  160. Tissir F., De-Backer O., Goffinet A.M., Lambert de Rouvroit C., Developmental expression profiles of Celsr (Flamingo) genes in the mouse, 10.1016/s0925-4773(01)00623-2
  161. Tissir Fadel, Goffinet André M., Expression of planar cell polarity genes during development of the mouse CNS, 10.1111/j.1460-9568.2006.04596.x
  162. Dickson B. J., Molecular Mechanisms of Axon Guidance, 10.1126/science.1072165
  163. Turner Christopher M, Adler Paul N, Distinct roles for the actin and microtubule cytoskeletons in the morphogenesis of epidermal hairs during wing development in Drosophila, 10.1016/s0925-4773(97)00194-9
  164. Wong L. L., Tissue polarity genes of Drosophila regulate the subcellular location for prehair initiation in pupal wing cells, 10.1083/jcb.123.1.209
  165. Singh J., Yanfeng W. A., Grumolato L., Aaronson S. A., Mlodzik M., Abelson family kinases regulate Frizzled planar cell polarity signaling via Dsh phosphorylation, 10.1101/gad.1961010
  166. Yanfeng W. A., Dev. Biol., 360, 132 (2011)
  167. Liu W., Sato A., Khadka D., Bharti R., Diaz H., Runnels L. W., Habas R., Mechanism of activation of the Formin protein Daam1, 10.1073/pnas.0707277105
  168. Schönichen André, Geyer Matthias, Fifteen formins for an actin filament: A molecular view on the regulation of human formins, 10.1016/j.bbamcr.2010.01.014
  169. Ishikawa H. O., Takeuchi H., Haltiwanger R. S., Irvine K. D., Four-jointed Is a Golgi Kinase That Phosphorylates a Subset of Cadherin Domains, 10.1126/science.1158159
  170. Sopko Richelle, Silva Elizabeth, Clayton Lesley, Gardano Laura, Barrios-Rodiles Miriam, Wrana Jeff, Varelas Xaralabos, Arbouzova Natalia I., Shaw Sanjeev, Saburi Sakura, Matakatsu Hitoshi, Blair Seth, McNeill Helen, Phosphorylation of the Tumor Suppressor Fat Is Regulated by Its Ligand Dachsous and the Kinase Discs Overgrown, 10.1016/j.cub.2009.05.049
  171. Thomas Chloe, Strutt David, The roles of the cadherins Fat and Dachsous in planar polarity specification inDrosophila : Fat/Dachsous and Planar Polarity, 10.1002/dvdy.22736
  172. Matakatsu H., Blair S. S., Separating planar cell polarity and Hippo pathway activities of the protocadherins Fat and Dachsous, 10.1242/dev.070367
  173. Mao Y., Dachs: an unconventional myosin that functions downstream of Fat to regulate growth, affinity and gene expression in Drosophila, 10.1242/dev.02427
  174. Mao Y., Mulvaney J., Zakaria S., Yu T., Morgan K. M., Allen S., Basson M. A., Francis-West P., Irvine K. D., Characterization of a Dchs1 mutant mouse reveals requirements for Dchs1-Fat4 signaling during mammalian development, 10.1242/dev.057166
  175. Saburi S., Hester I., Goodrich L., McNeill H., Functional interactions between Fat family cadherins in tissue morphogenesis and planar polarity, 10.1242/dev.077461
  176. Saburi Sakura, Hester Ian, Fischer Evelyne, Pontoglio Marco, Eremina Vera, Gessler Manfred, Quaggin Sue E, Harrison Robert, Mount Richard, McNeill Helen, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease, 10.1038/ng.179
  177. Backman Mattias, Machon Ondrej, Van Den Bout Christiaan J., Krauss Stefan, Targeted disruption of mouse Dach1 results in postnatal lethality, 10.1002/dvdy.10210
  178. Davis R. J., Shen W., Sandler Y. I., Amoui M., Purcell P., Maas R., Ou C.-N., Vogel H., Beaudet A. L., Mardon G., Dach1 Mutant Mice Bear No Gross Abnormalities in Eye, Limb, and Brain Development and Exhibit Postnatal Lethality, 10.1128/mcb.21.5.1484-1490.2001
  179. Davis Richard J., Pesah Yakov I., Harding Mark, Paylor Richard, Mardon Graeme, MouseDach2 mutants do not exhibit gross defects in eye development or brain function, 10.1002/gene.20188
  180. Ciani L., Patel A., Allen N. D., ffrench-Constant C., Mice Lacking the Giant Protocadherin mFAT1 Exhibit Renal Slit Junction Abnormalities and a Partially Penetrant Cyclopia and Anophthalmia Phenotype, 10.1128/mcb.23.10.3575-3582.2003
  181. Morris Luc G T, Kaufman Andrew M, Gong Yongxing, Ramaswami Deepa, Walsh Logan A, Turcan Şevin, Eng Stephanie, Kannan Kasthuri, Zou Yilong, Peng Luke, Banuchi Victoria E, Paty Phillip, Zeng Zhaoshi, Vakiani Efsevia, Solit David, Singh Bhuvanesh, Ganly Ian, Liau Linda, Cloughesy Timothy C, Mischel Paul S, Mellinghoff Ingo K, Chan Timothy A, Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation, 10.1038/ng.2538
  182. Barlow Jillian L, Drynan Lesley F, Hewett Duncan R, Holmes Luke R, Lorenzo-Abalde Silvia, Lane Alison L, Jolin Helen E, Pannell Richard, Middleton Angela J, Wong See Heng, Warren Alan J, Wainscoat James S, Boultwood Jacqueline, McKenzie Andrew N J, A p53-dependent mechanism underlies macrocytic anemia in a mouse model of human 5q– syndrome, 10.1038/nm.2063
  183. Deans Michael R., Krol Alexandra, Abraira Victoria E., Copley Catherine O., Tucker Andrew F., Goodrich Lisa V., Control of Neuronal Morphology by the Atypical Cadherin Fat3, 10.1016/j.neuron.2011.06.026
  184. Probst Barbara, Rock Rebecca, Gessler Manfred, Vortkamp Andrea, Püschel Andreas W., The rodent Four-jointed ortholog Fjx1 regulates dendrite extension, 10.1016/j.ydbio.2007.09.054