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Dosimetry of yttrium-labelled radiopharmaceuticals for internal therapy: 86Y or 90Y imaging?

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Walrand, Stephan [UCL] Flux, Glenn D Konijnenberg, Mark W Valkema, Roelf Krenning, Eric P Lhommel, Renaud [UCL] Pauwels, Stanislas [UCL] Jamar, François [UCL]

This paper reviews issues concerning (86)Y positron emission tomography (PET), (90)Y PET and (90)Y bremsstrahlung imaging. Specific methods and corrections developed for quantitative imaging, for application in preclinical and clinical studies, and to assess (90)Y dosimetry are discussed. The potential imaging capabilities with the radioisotopes (87)Y and (88)Y are also considered. Additional studies required to assess specific unaddressed issues are also identified.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 2011
Language Anglais
Journal information "European Journal of Nuclear Medicine and Molecular Imaging" - Vol. 38, no. Suppl. 1, p. S57-568 (2011)
Peer reviewed yes
Publisher Springer ((Germany) Heidelberg)
issn 1619-7070
e-issn 1619-7089
Publication status Publié
Affiliations UCL - (SLuc) Service de médecine nucléaire
UCL - SSS/IREC/MIRO - Pôle d'imagerie moléculaire, radiothérapie et oncologie
MESH Subject Animals ; Tomography, Emission-Computed ; Yttrium Radioisotopes ; Forecasting ; Half-Life ; Humans ; Positron-Emission Tomography ; Radiometry ; Radiopharmaceuticals ; Radiotherapy Planning, Computer-Assisted ; Tissue Distribution
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Permanent URL http://hdl.handle.net/2078.1/126185