User menu

Accès à distance ? S'identifier sur le proxy UCLouvain

Validity of the five-word test for the evaluation of verbal episodic memory and dementia in a memory clinic setting.

Primary tabs

Mormont, Eric [UCL] Jamart, Jacques [UCL] Robaye, Laurence [UCL]

BACKGROUND: The five-word test (FWT) uses semantic clues to optimize the encoding and retrieval of 5 items. Our objective was to assess the validity of the FWT as a measure of episodic memory when compared with the Free and Cued Selective Reminding Test (FCSRT), and its ability to distinguish participants with any dementia and especially Alzheimer disease (AD) from those with only subjective complaints. METHODS: Two hundred participants with Mini-Mental State Examination (MMSE) >15 were prospectively evaluated. The sum of the immediate and delayed free recalls of the FWT is called the free recall score (FRS). The sum of the immediate free, immediate cued, delayed free, and delayed cued recalls is called the total recall score (TRS). A total weighted score (TWS) is calculated using this formula: (free recalls × 2) + cued recalls. RESULTS: The correlation between FRS and the free recall scores of the FCSRT and between TRS and the total recall scores of the FCSRT was significant (r (s) ranges from .74-.84, P < .001). Area under the receiver--operating characteristic (ROC) curves of the MMSE, FRS, TRS, and TWS were not statistically different. A TWS at a cutoff value ≤15 could discriminate any dementia from subjective complaints with a sensitivity of 75% and a specificity of 95.9% or AD from subjective complaints with a sensitivity of 90.2% and a specificity of 95.9%. CONCLUSION: The FWT is a valid test of verbal episodic memory. It is useful to discriminate dementia especially AD from isolated subjective complaints.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès restreint
Publication date 2012
Language Anglais
Journal information "Journal of geriatric psychiatry and neurology" - Vol. 25, no.2, p. 78-84 (2012)
Peer reviewed yes
Publisher SAGE publications
issn 0891-9887
e-issn 1552-5708
Publication status Publié
Affiliations UCL - SSS/IONS/NEUR - Clinical Neuroscience
UCL - (MGD) Service de neurologie
UCL - SSS/IONS/NEUR - Clinical Neuroscience
UCL - SSS/IREC/MONT - Pôle Mont Godinne
UCL - (MGD) Unité de support scientifique
MESH Subject Adult ; Memory, Episodic ; Mental Recall ; Middle Aged ; Neuropsychological Tests ; Reproducibility of Results ; Semantics ; Aged ; Aged, 80 and over ; Alzheimer Disease ; Cues ; Dementia ; Female ; Humans ; Male
Links
  1. Folstein Marshal F., Folstein Susan E., McHugh Paul R., “Mini-mental state”, 10.1016/0022-3956(75)90026-6
  2. Tombaugh Tom N., McIntyre Nancy J., The Mini-Mental State Examination: A Comprehensive Review, 10.1111/j.1532-5415.1992.tb01992.x
  3. Grober E., Buschke H., Crystal H., Bang S., Dresner R., Screening for dementia by memory testing, 10.1212/wnl.38.6.900
  4. Dubois Bruno, Feldman Howard H, Jacova Claudia, Cummings Jeffrey L, DeKosky Steven T, Barberger-Gateau Pascale, Delacourte André, Frisoni Giovanni, Fox Nick C, Galasko Douglas, Gauthier Serge, Hampel Harald, Jicha Gregory A, Meguro Kenichi, O'Brien John, Pasquier Florence, Robert Philippe, Rossor Martin, Salloway Steven, Sarazin Marie, de Souza Leonardo C, Stern Yaakov, Visser Pieter J, Scheltens Philip, Revising the definition of Alzheimer's disease: a new lexicon, 10.1016/s1474-4422(10)70223-4
  5. Dubois B, Presse Med, 31, 1696 (2002)
  6. Croisile B., Astier J.-L., Beaumont C., Mollion H., Le Test des cinq mots dans les formes légères de maladie d’Alzheimer : comparaison du score total, du Score Total Pondéré, du Score d’apprentissage et du Score de mémoire dans trois classes d’âge (60 ans, 70 ans, 80 ans), 10.1016/j.neurol.2010.03.008
  7. Grober Ellen, Buschke Herman, Genuine memory deficits in dementia, 10.1080/87565648709540361
  8. Lawton M. P., Brody E. M., Assessment of Older People: Self-Maintaining and Instrumental Activities of Daily Living, 10.1093/geront/9.3_part_1.179
  9. American Psychiatric Association, Diagnostic and Statistical Manual of Mental Disorders (1994)
  10. Petersen Ronald C., Doody Rachelle, Kurz Alexander, Mohs Richard C., Morris John C., Rabins Peter V., Ritchie Karen, Rossor Martin, Thal Leon, Winblad Bengt, Current Concepts in Mild Cognitive Impairment, 10.1001/archneur.58.12.1985
  11. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E. M., Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA Work Group* under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease, 10.1212/wnl.34.7.939
  12. Roman G. C., Tatemichi T. K., Erkinjuntti T., Cummings J. L., Masdeu J. C., Garcia J. H., Amaducci L., Orgogozo J.-M., Brun A., Hofman A., Moody D. M., O'Brien M. D., Yamaguchi T., Grafman J., Drayer B. P., Bennett D. A., Fisher M., Ogata J., Kokmen E., Bermejo F., Wolf P. A., Gorelick P. B., Bick K. L., Pajeau A. K., Bell M. A., DeCarli C., Culebras A., Korczyn A. D., Bogousslavsky J., Hartmann A., Scheinberg P., Vascular dementia: Diagnostic criteria for research studies: Report of the NINDS-AIREN International Workshop, 10.1212/wnl.43.2.250
  13. McKeith IG, Third report of the DLB consortium. Neurology., 65, 1863 (2005)
  14. Clinical and neuropathological criteria for frontotemporal dementia. The Lund and Manchester Groups., 10.1136/jnnp.57.4.416
  15. Van der Linden M, L’évaluation des troubles de la mémoire, 25 (2004)
  16. Baddeley AD, Doors and People: A Test of Visual and Verbal Recall and Recognition (1994)
  17. de Partz MP, LEXIS: Tests pour le diagnostic des troubles lexicaux chez le patient aphasique (2002)
  18. Hogrefe CJ, Test d2 (1962)
  19. Stroop J. R., Studies of interference in serial verbal reactions., 10.1037/h0054651
  20. Reitan RM, The Halstead-Reitan Neuropsychological Test Battery (1985)
  21. Moms J. C., Heyman A., Mohs R. C., Hughes J. P., van Belle G., Fillenbaum G., Mellits E. D., Clark C., The Consortium to Establish a Registry for Alzheimer's Disease (CERAD). Part I. Clinical and neuropsychological assesment of Alzheimer's disease, 10.1212/wnl.39.9.1159
  22. Rouleau Isabelle, Salmon David P, Butters Nelson, Kennedy Colleen, McGuire Katheryn, Quantitative and qualitative analyses of clock drawings in Alzheimer's and Huntington's disease, 10.1016/0278-2626(92)90112-y
  23. Cullen B., O'Neill B., Evans J. J, Coen R. F, Lawlor B. A, A review of screening tests for cognitive impairment, 10.1136/jnnp.2006.095414
  24. Buschke H., Kuslansky G., Katz M., Stewart W. F., Sliwinski M. J., Eckholdt H. M., Lipton R. B., Screening for dementia with the Memory Impairment Screen, 10.1212/wnl.52.2.231
  25. Kuslansky Gail, Buschke Herman, Katz Mindy, Sliwinski Martin, Lipton Richard B., Screening for Alzheimer's Disease: The Memory Impairment Screen Versus the Conventional Three-Word Memory Test, 10.1046/j.1532-5415.2002.50265.x
  26. Cowppli-Bony P., Fabrigoule C., Letenneur L., Ritchie K., Alpérovitch A., Dartigues J.F., Dubois B., Le test des 5 mots : validité dans la détection de la maladie d’Alzheimer dans la population générale, 10.1016/s0035-3787(05)85194-x
  27. Croisile B., Astier J.L., Beaumont C., Étalonnage du test des cinq mots dans une population de sujets sains, 10.1016/s0035-3787(07)90404-x
Bibliographic reference Mormont, Eric ; Jamart, Jacques ; Robaye, Laurence. Validity of the five-word test for the evaluation of verbal episodic memory and dementia in a memory clinic setting.. In: Journal of geriatric psychiatry and neurology, Vol. 25, no.2, p. 78-84 (2012)
Permanent URL http://hdl.handle.net/2078.1/122862