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Displaying 14 results.
    • Journal article
    Functional impacts of the ubiquitin-proteasome system on DNA damage recognition in global genome nucleotide excision repair.
    Sakai, Wataru Yuasa-Sunagawa, Mayumi Kusakabe, Masayuki Kishimoto, Aiko Matsui, Takeshi Kaneko, Yuki Akagi, Jun-Ichi Huyghe, Nicolas[UCL] Ikura, Masae Ikura, Tsuyoshi Hanaoka, Fumio Yokoi, Masayuki Sugasawa, Kaoru (2020) Scientific reports — Vol. 10, no.1, p. 19704 [1-15] (2020)
    • Speech
    599P R-IMMUNE: A phase Ib/II study to evaluate safety and efficacy of atezolizumab combined with radio-chemotherapy in a preoperative setting for patients with locally advanced rectal cancer (LARC)
    Carrasco, Javier Beniuga, Gabriela[UCL] Mourin, Anne[UCL] Baldin, Paméla[UCL] Sinapi, Isabelle Schroeder, David De Cuyper, Astrid[UCL] Sclafani, Francesco Hendlisz, Alain van Laethem, Jean-Luc Boulanger, Anne-Sophie Van Ooteghem, Geneviève[UCL] Dermine, Alexandre Delmarcelle, Sophie Huyghe, Nicolas[UCL] Bar, Isabelle Van den Eynde, Marc[UCL] (2023) ESMO Congress 2023 — (Spain) Madrid
    • Speech
    Interim analysis of the AVETUXIRI Trial: Avelumab combined with cetuximab and irinotecan for treatment of refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC)—A proof of concept, open-label, nonrandomized phase IIa study.
    Van den Eynde, Marc[UCL] Huyghe, Nicolas De Cuyper, Astrid[UCL] Sinapi, Isabelle Ferrier, Marie Gilet, Mélanie Van Maanen, Aline[UCL] Castella, Marie-Laure[UCL] Galon, Jerome Carrasco, Javier (2021) 2021 Gastrointestinal Cancers Symposium —
    • Journal article
    Multiplex Immunofluorescence Combined with Spatial Image Analysis for the Clinical and Biological Assessment of the Tumor Microenvironment
    Huyghe, Nicolas[UCL] Benidovskaya, Elena[UCL] Beyaert, Simon[UCL] Daumerie, Aurélie[UCL] Maestre Osorio, Finoula[UCL] Aboubakar Nana, Frank[UCL] Bouzin, Caroline[UCL] Van den Eynde, Marc[UCL] (2023) Journal of visualized experiments — Vol. 196, p. e65220 [1-17] (2023)
    • Speech
    635P Avelumab (AVE) combined with cetuximab (CET) and irinotecan (IRI) for the treatment of refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): The AVETUXIRI phase II study
    Van den Eynde, Marc[UCL] Huyghe, Nicolas[UCL] Sinapi, Isabelle De Cuyper, Astrid[UCL] Verstraelen, Eleonore Goffette, Pierre[UCL] Ghaye, Benoît[UCL] Papier, Matthias Bedognetti, Davide van Maanen, Aline[UCL] Castella, Marie-Laure[UCL] Galon, Jerôme Carrasco, Javier (2023) ESMO Congress 2023 — (Spain) Madrid
    • Journal article
    Immunotherapy with immune checkpoint inhibitors in colorectal cancer: what is the future beyond deficient mismatch-repair tumours?
    Huyghe, Nicolas[UCL] Baldin, Pamela[UCL] Van Den Eynde, Marc[UCL] (2020) Gastroenterology report — Vol. 8, no.1, p. 11-24 (2020)
    • Speech
    Interim analysis of the phase II AVETUXIRI trial: Avelumab combined with cetuximab and irinotecan for treatment of refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC).
    Huyghe, Nicolas[UCL] De Cuyper, Astrid[UCL] Sinapi, Isabelle Vempalli, Fazulur Rehaman Rinchai, Darawan Beyaert, Simon[UCL] Verstraelen, Eleonore Goffette, Pierre[UCL] Ghaye, Benoît[UCL] Gilet, Mélanie Van Maanen, Aline[UCL] Castella, Marie-Laure[UCL] Mlecnik, Bernhard Carrasco, Javier Galon, Jerome Bedognetti, Davide Van den Eynde, Marc[UCL] (2022) 2022 ASCO Annual Meeting I —
    • Journal article
    The Link between the Multiverse of Immune Microenvironments in Metastases and the Survival of Colorectal Cancer Patients.
    Van den Eynde, Marc[UCL] Mlecnik, Bernhard Bindea, Gabriela Fredriksen, Tessa Church, Sarah E Lafontaine, Lucie Haicheur, Nacilla Marliot, Florence Angelova, Mihaela Vasaturo, Angela Bruni, Daniela Mourin, Anne[UCL] Baldin, Paméla[UCL] Huyghe, Nicolas[UCL] Haustermans, Karin Debucquoy, Annelies Van Cutsem, Eric Gigot, Jean-François[UCL] Hubert, Catherine[UCL] Kartheuser, Alex[UCL] Remue, Christophe[UCL] Léonard, Daniel[UCL] Valge-Archer, Viia Pagès, Franck Machiels, Jean-Pascal[UCL] Galon, Jérôme (2018) Cancer cell — Vol. 34, no. 6, p. 1012-1026.e3 (2018)
    • Speech
    2237P Avelumab (AVE), cetuximab (CET) and irinotecan (IRI) for treatment refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): Translational analyses of the AVETUXIRI phase II trial
    Huyghe, Nicolas[UCL] Benidovskaya, Elena[UCL] Masoodi, Tariq Carrasco, Javier De Cuyper, Astrid[UCL] Sinapi, Isabelle Vempalli, Fazulur Verstraelen, Eleonore Goffette, Pierre[UCL] Ghaye, Benoît[UCL] Papier, M. Bedognetti, Davide van Maanen, Aline[UCL] Castella, Marie-Laure[UCL] Galon, Jérôme Van den Eynde, Marc[UCL] (2023) ESMO Congress 2023 — (Spain) Madrid
    • Journal article
    Prognostic assessment of resected colorectal liver metastases integrating pathological features, RAS mutation and Immunoscore.
    Baldin, Paméla[UCL] Van den Eynde, Marc[UCL] Mlecnik, Bernhard Bindea, Gabriela Beniuga, Gabriela Carrasco, Javier Haicheur, Nacilla Marliot, Florence Lafontaine, Lucie Fredriksen, Tessa Lanthier, Nicolas[UCL] Hubert, Catherine[UCL] Navez, Benoît[UCL] Huyghe, Nicolas[UCL] Pagès, Franck Mourin, Anne[UCL] Galon, Jérôme Komuta, Mina[UCL] (2021) The journal of pathology. Clinical research — Vol. 7, no. 1, p. 27-41 (2021)
    • Journal article
    Biomarkers of Response and Resistance to Immunotherapy in Microsatellite Stable Colorectal Cancer: Toward a New Personalized Medicine.
    Huyghe, Nicolas[UCL] Benidovskaya, Elena[UCL] Stevens, Philippe[UCL] Van den Eynde, Marc[UCL] (2022) Cancers — Vol. 14, no. 9, p. 2241 [1-30] (2022)
    • Journal article
    Specific post-translational modifications of soluble tau protein distinguishes Alzheimer’s disease and primary tauopathies
    Kyalu Ngoie Zola, Nathalie[UCL] Balty, Clémence[UCL] Pyr dit Ruys, Sébastien[UCL] Vanparys, Axelle[UCL] Huyghe, Nicolas[UCL] Herinckx, Gaëtan[UCL] Johanns, Manuel[UCL] Boyer, Emilien[UCL] Kienlen-Campard, Pascal[UCL] Rider, Mark H.[UCL] Vertommen, Didier[UCL] Hanseeuw, Bernard[UCL] (2023) Nature communications — Vol. 14, no. 1, p. 3706 [1-17] (2023)
    • Speech
    120P Avelumab (AVE), cetuximab (CET) and irinotecan (IRI) for treatment refractory microsatellite stable (MSS) metastatic colorectal cancer (mCRC): Characterization of the circulating immune response in the AVETUXIRI phase II trial
    Benidovskaya, Elena[UCL] Huyghe, Nicolas[UCL] Carrasco, Javier De Cuyper, Astrid[UCL] Sinapi, Isabelle Verstraelen, Eléonore[UCL] Goffette, Pierre[UCL] Ghaye, Benoît[UCL] Papier, M. Van Maanen, Aline[UCL] Castella, Marie-Laure[UCL] Galon, Jérôme Van den Eynde, Marc[UCL] (2024) the ESMO Gastrointestinal Cancers Congress 2024 — (Germany) Munich
    • Journal article
    Tumor Microenvironment Modifications Induced by Afatinib in Squamous Cell Carcinoma of the Head and Neck: A Window-of-Opportunity Study (EORTC-90111-24111).
    Beyaert, Simon[UCL] Loriot, Axelle[UCL] Huyghe, Nicolas[UCL] Goebbels, Rose-Marie[UCL] Mendola, Antonella[UCL] Govaerts, Anne-Sophie Fortpied, Catherine Baldin, Paméla[UCL] Licitra, Lisa F Lalami, Yassine Clement, Paul M Machiels, Jean-Pascal[UCL] Schmitz, Sandra[UCL] (2023) Clinical cancer research — Vol. 29, no. 20, p. 4076-4087 (2023)