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Displaying 17 results.
    • Journal article
    PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease.
    Morel, Milena Couturier, Julien[UCL] Lafay-Chebassier, Claire Paccalin, Marc Page, Guylène (2009) Journal of Cellular and Molecular Medicine : a journal of translational medicine — Vol. 13, no. 8A, p. 1476-1488 (2009)
    • Journal article
    The mTOR inhibitor RAD001 augments radiation-induced growth inhibition in a hepatocellular carcinoma cell line by increasing autophagy
    Altmeyer, Anaïs Josset, Elodie Denis, Jean-Marc[UCL] Gueulette, John[UCL] Slabbert, Jakobus Mutter, Didier Noël, Georges Bischoff, Pierre (2012) International Journal of Oncology — Vol. 41, no.4, p. 1381-1386 (2012)
    • Journal article
    Modulation of autophagy and ubiquitin-proteasome pathways during ultra-endurance running.
    Jamart, Cécile[UCL] Francaux, Marc[UCL] Millet, Guillaume Y Deldicque, Louise Frère, Delphine Féasson, Léonard (2012) Journal of Applied Physiology — Vol. 112, no. 9, p. 1529-1537 (2012)
    • Journal article
    Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.
    Govaere, Olivier Wouters, Jasper Petz, Michaela Vandewynckel, Yves-Paul Van den Eynde, Kathleen Van den Broeck, Anke Verhulst, Stefaan Dollé, Laurent Gremeaux, Lies Ceulemans, An Nevens, Frederik van Grunsven, Leo A Topal, Baki Vankelecom, Hugo Giannelli, Gianluigi Van Vlierberghe, Hans Mikulits, Wolfgang Komuta, Mina[UCL] Roskams, Tania (2016) Journal of Hepatology — Vol. 64, no. 3, p. 609-617 (2016)
    • Journal article
    A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.
    Schnitzbauer, Andreas A Zuelke, Carl Graeb, Christian Rochon, Justine Bilbao, Itxarone Burra, Patrizia de Jong, Koert P Duvoux, Christophe Kneteman, Norman M Adam, Rene Bechstein, Wolf O Becker, Thomas Beckebaum, Susanne Chazouillères, Olivier Cillo, Umberto Colledan, Michele Fändrich, Fred Gugenheim, Jean Hauss, Johann P Heise, Michael Hidalgo, Ernest Jamieson, Neville Königsrainer, Alfred Lamby, Philipp E Lerut, Jan[UCL] Mäkisalo, Heikki Margreiter, Raimund Mazzaferro, Vincenzo Mutzbauer, Ingrid Otto, Gerd Pageaux, Georges-Philippe Pinna, Antonio D Pirenne, Jacques Rizell, Magnus Rossi, Giorgio Rostaing, Lionel Roy, Andre Turrion, Victor Sanchez Schmidt, Jan Troisi, Roberto I van Hoek, Bart Valente, Umberto Wolf, Philippe Wolters, Heiner Mirza, Darius F Scholz, Tim Steininger, Rudolf Soderdahl, Gunnar Strasser, Simone I Jauch, Karl-Walter Neuhaus, Peter Schlitt, Hans J Geissler, Edward K (2010) BMC Cancer — Vol. 10, no. 190, p. [1-8] (2010)
    • Journal article
    Myostatin and the skeletal muscle atrophy and hypertrophy signaling pathways.
    Rodriguez, Julie[UCL] Vernus, Barbara Chelh, Ilham Cassar-Malek, Isabelle Gabillard, Jean-Charles Hadj Sassi, Abdessatar Seiliez, Iban Picard, Brigitte Bonnieu, Anne (2014) Cellular and molecular life sciences — Vol. 71, no.22, p. 4361-4371 (2014)
    • Journal article
    Myostatin inactivation increases myotube size through regulation of translational initiation machinery.
    Rodriguez, Julie[UCL] Vernus, Barbara Toubiana, Mylène Jublanc, Elodie Tintignac, Lionel Leibovitch, Serge Bonnieu, Anne (2011) Journal of cellular biochemistry — Vol. 112, no.12, p. 3531-3542 (2011)
    • Journal article
    The type 1 insulin-like growth factor receptor (IGF-IR) pathway is mandatory for the follistatin-induced skeletal muscle hypertrophy
    Kalista, Stéphanie[UCL] Schakman, Olivier[UCL] Gilson, Hélène[UCL] Lause, Pascale[UCL] Demeulder, Bénédicte[UCL] Bertrand, Luc[UCL] Pende, M Thissen, Jean-Paul[UCL] (2012) Endocrinology — Vol. 153, no. 1, p. 241-253 (2012)
    • Journal article
    Evidence of molecular links between PKR and mTOR signalling pathways in Abeta neurotoxicity: role of p53, Redd1 and TSC2.
    Morel, Milena Couturier, Julien[UCL] Pontcharraud, Raymond Gil, Roger Fauconneau, Bernard Paccalin, Marc Page, Guylène (2009) Neurobiology of Disease — Vol. 36, no. 1, p. 151-161 (2009)
    • Journal article
    Salirasib inhibits the growth of hepatocarcinoma cell lines in vitro and tumor growth in vivo through ras and mTOR inhibition
    Charette, Nicolas[UCL] Horsmans, Yves[UCL] Starkel, Peter[UCL] De Saeger, Christine[UCL] Lannoy, Valerie[UCL] Leclercq, Isabelle[UCL] (2010) Molecular Cancer — Vol. 9, p. 256 (2010)
    • Journal article
    Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
    Rodenak-Kladniew, Boris Castro, Agustina Stärkel, Peter[UCL] De Saeger, Christine García de Bravo, Margarita Crespo, Rosana (2018) Life sciences — Vol. 199, p. 48-59 (2018)
    • Journal article
    1,8-Cineole promotes G0/G1 cell cycle arrest and oxidative stress-induced senescence in HepG2 cells and sensitizes cells to anti-senescence drugs.
    Rodenak-Kladniew, Boris Castro, Agustina Starkel, Peter[UCL] Galle, Marianela Crespo, Rosana (2020) Life sciences — Vol. 243, p. 117271 [1-13] (2020)
    • Journal article
    Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways.
    Rodenak-Kladniew, Boris Castro, Agustina Starkel, Peter[UCL] De Saeger, Christine[UCL] García de Bravo, Margarita Crespo, Rosana (2018) Life sciences — Vol. 199, p. 48-59 (2018)
    • Journal article
    Autosomal dominant polycystic kidney disease: the changing face of clinical management.
    Ong, Albert C M Devuyst, Olivier[UCL] Knebelmann, Bertrand Walz, Gerd ERA-EDTA Working Group for Inherited Kidney Diseases (2015) The Lancet — Vol. 385, no. 9981, p. 1993-2002 (2015)
    • Journal article
    Targeting the PI3K/AKT/mTOR and Raf/MEK/ERK pathways in the treatment of breast cancer.
    Saini, Kamal S Loi, Sherene de Azambuja, Evandro Metzger-Filho, Otto Saini , Monika Lamba[UCL] Ignatiadis, Michail Dancey, Janet E Piccart-Gebhart, Martine J (2013) Cancer Treatment Reviews — Vol. 39, no.8, p. 935-946 (2013)
    • Journal article
    Activation of the cardiac mTOR/p70(S6K) pathway by leucine requires PDK1 and correlates with PRAS40 phosphorylation
    Canedo, Cossette Sanchez[UCL] Demeulder, Bénédicte[UCL] Ginion, Audrey[UCL] Bayascas, Jose R. Balligand, Jean-Luc[UCL] Alessi, Dario R. Vanoverschelde, Jean-Louis[UCL] Beauloye, Christophe[UCL] Hue, Louis[UCL] Bertrand, Luc[UCL] (2010) American Journal of Physiology: Endocrinology and Metabolism — Vol. 298, no. 4, p. E761-9 (2010)
    • Journal article
    Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake.
    Ginion, Audrey[UCL] Auquier, Julien[UCL] Benton, Carley R[UCL] Mouton, Céline[UCL] Vanoverschelde, Jean-Louis[UCL] Hue, Louis[UCL] Horman, Sandrine[UCL] Beauloye, Christophe[UCL] Bertrand, Luc[UCL] (2011) American Journal of Physiology: Heart and Circulatory Physiology — Vol. 301, no. 2, p. H469-77 (2011)