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Displaying 19 results.
    • Journal article
    Modulation of the cellular accumulation and intracellular activity of daptomycin towards phagocytized Staphylococcus aureus by the P-glycoprotein (MDR1) efflux transporter in human THP-1 macrophages and madin-darby canine kidney cells
    Lemaire, Sandrine[UCL] Van Bambeke, Françoise[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Tulkens, Paul M.[UCL] (2007) Antimicrobial Agents and Chemotherapy — Vol. 51, no. 8, p. 2748-2757 (2007)
    • Journal article
    Molecular models of human P-glycoprotein in two different catalytic states
    Becker, Jean-Paul Depret, Grégoire Van Bambeke, Françoise[UCL] Tulkens, Paul M.[UCL] Prévost, Martine (2009) BMC Structural Biology — Vol. 9, no. 3, p. [1-18] (2009)
    • Journal article
    Detection of intracellular antigens by flow cytometry: comparison of two chemical methods and microwave heating.
    Millard, Isabelle[UCL] Degrave, E Philippe, Marianne[UCL] Gala, Jean-Luc[UCL] (1998) Clinical chemistry — Vol. 44, no. 11, p. 2320-30 (1998)
    • Journal article
    Influence of P-glycoprotein inhibitors on accumulation of macrolides in J774 murine macrophages
    Seral, Cristina[UCL] Michot, Jean-Michel[UCL] Chanteux, Hugues[UCL] Mingeot-Leclercq, Marie-Paule[UCL] Tulkens, Paul M.[UCL] Van Bambeke, Françoise[UCL] (2003) Antimicrobial Agents and Chemotherapy — Vol. 47, no. 3, p. 1047-1051 (2003)
    • Journal article
    Influence of P-glycoprotein and MRP efflux pump inhibitors on the intracellular activity of azithromycin and ciprofloxacin in macrophages infected by Listeria monocytogenes or Staphylococcus aureus.
    Seral, Cristina Carryn, Stéphane Tulkens, Paul M.[UCL] Van Bambeke, Françoise[UCL] (2003) The Journal of antimicrobial chemotherapy — Vol. 51, no. 5, p. 1167-73 (2003)
    • Journal article
    CYP3A5 and ABCB1 polymorphisms influence tacrolimus concentrations in peripheral blood mononuclear cells after renal transplantation.
    Capron, Arnaud[UCL] Mourad, Michel[UCL] De Meyer, Martine[UCL] De Pauw, Luc[USL-B] Eddour, Djamila Chaib[UCL] Latinne, Dominique[UCL] Elens, Laure[UCL] Haufroid, Vincent[UCL] Wallemacq, Pierre[UCL] (2010) Pharmacogenomics — Vol. 11, no. 5, p. 703-714 (2010)
    • Journal article
    CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-Comparison with other conazole pesticides.
    Sergent, Thérèse[UCL] Dupont, Isabelle[UCL] Jassogne, Coralie Ribonnet, Laurence[UCL] van der Heiden, Edwige Scippo, Marie-Louise Muller, Marc McAlister, Dan Pussemier, Luc Larondelle, Yvan[UCL] Schneider, Yves-Jacques[UCL] (2008) Toxicology letters — Vol. 184, no. 3, p. 159-68 (2009)
    • Journal article
    Time of drug administration, CYP3A5 and ABCB1 genotypes, and analytical method influence tacrolimus pharmacokinetics : a population pharmacokinetic study
    Musuamba Tshinanu, Flora[UCL] Mourad, Michel[UCL] Haufroid, Vincent[UCL] Delattre, Isabelle[UCL] Verbeeck, Roger-Karel[UCL] Wallemacq, Pierre[UCL] (2009) Therapeutic Drug Monitoring — Vol. 31, no. 6, p. 734-742 (2009)
    • Journal article
    P-glycoprotein positive, drug resistant invasive lymphoepithelial thymoma: treatment response to chemotherapy with cyclosporin and quinine.
    Gala, Jean-Luc[UCL] Noël, Henri[UCL] Rodhain, J. Ma, D F Ferrant, Augustin[UCL] (1995) Journal of clinical pathology — Vol. 48, no. 7, p. 679-81 (1995)
    • Journal article
    Predicting the three-dimensional structure of human P-glycoprotein in absence of ATP by computational techniques embodying crosslinking data: insight into the mechanism of ligand migration and binding sites.
    Vandevuer, Stéphane Van Bambeke, Françoise[UCL] Tulkens, Paul M.[UCL] Prévost, Martine (2006) Proteins — Vol. 63, no. 3, p. 466-78 (2006)
    • Journal article
    The influence of genetic polymorphisms of cytochrome P450 3A5 and ABCB1 on starting dose- and weight-standardized tacrolimus trough concentrations after kidney transplantation in relation to renal function.
    Mourad, Michel[UCL] Wallemacq, Pierre[UCL] De Meyer, Martine Brandt, Dimitri Van Kerkhove, Valérie Malaise, Jacques Chaïb Eddour, Djamila Lison, Dominique[UCL] Haufroid, Vincent[UCL] (2006) Clinical chemistry and laboratory medicine : CCLM / FESCC — Vol. 44, no. 10, p. 1192-8 (2006)
    • Journal article
    Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids.
    Mourad, Michel[UCL] Mourad, Georges Wallemacq, Pierre[UCL] Garrigue, Valérie Van Bellingen, Christophe Van Kerckhove, Valérie[UCL] De Meyer, Martine Malaise, Jacques Eddour, Djamila Chaib Lison, Dominique[UCL] Squifflet, Jean-Paul[UCL] Haufroid, Vincent[UCL] (2005) Transplantation — Vol. 80, no. 7, p. 977-84 (2005)
    • Journal article
    Biotransformation enzymes and drug transporters pharmacogenetics in relation to immunosuppressive drugs: impact on pharmacokinetics and clinical outcome
    Mourad, Michel[UCL] Wallemacq, Pierre[UCL] De Meyer, Martine[UCL] Malaise, Jacques[UCL] De Pauw, Luc[UCL] Chaib Eddour, Djamila[UCL] Goffin, Eric[UCL] Lerut, Jan[UCL] Haufroid, Vincent[UCL] (2008) Transplantation — Vol. 85, no. 7 (suppl.), p. S19-S24 (2008)
    • Journal article
    The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis.
    van der Holt, Bronno Löwenberg, Bob Burnett, Alan K Knauf, Wolfgang U Shepherd, John Piccaluga, Pier Paolo Ossenkoppele, Gert J Verhoef, Gregor E G Ferrant, Augustin[UCL] Crump, Michael Selleslag, Dominik Theobald, Matthias Fey, Martin F Vellenga, Edo Dugan, Margaret Sonneveld, Pieter (2005) Blood — Vol. 106, no. 8, p. 2646-54 (2005)
    • Journal article
    CYP3A5 and ABCB1 polymorphisms and tacrolimus pharmacokinetics in renal transplant candidates: guidelines from an experimental study.
    Haufroid, Vincent[UCL] De Meyer, Martine[UCL] Wallemacq, Pierre[UCL] Van Kerckhove, Valérie[UCL] Elens, Laure[UCL] Eddour, D C Malaise, Jacques Lison, Dominique[UCL] Mourad, Michel[UCL] (2006) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons — Vol. 6, no. 11, p. 2706-13 (2006)
    • Journal article
    1199G>A and 2677G>T/A polymorphisms of ABCB1 independently affect tacrolimus concentration in hepatic tissue after liver transplantation.
    Elens, Laure[UCL] Capron, Arnaud[UCL] Kerckhove, Valérie Van Lerut, Jan[UCL] Mourad, Michel[UCL] Lison, Dominique[UCL] Wallemacq, Pierre[UCL] Haufroid, Vincent[UCL] (2007) Pharmacogenetics and Genomics — Vol. 17, no. 10, p. 873-883 (2007)
    • Journal article
    Decreased P-glycoprotein (P-gp/MDR1) expression in inflamed human intestinal epithelium is independent of PXR protein levels.
    Blokzijl, Hans Vander Borght, Sara Bok, Lisette I H Libbrecht, Louis[UCL] Geuken, Mariska van den Heuvel, Fiona A J Dijkstra, Gerard Roskams, Tania A D Moshage, Han Jansen, Peter L M Faber, Klaas Nico (2007) Inflammatory Bowel Diseases — Vol. 13, no.6, p. 710-720 (2007)
    • Journal article
    High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease.
    Ros, Jenny E Libbrecht, Louis[UCL] Geuken, Mariska Jansen, Peter L M Roskams, Tania A D (2003) Journal of Pathology — Vol. 200, no.5, p. 553-560 (2003)
    • Journal article
    CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population.
    Allabi, Aurel C Gala, Jean-Luc[UCL] Horsmans, Yves[UCL] (2005) Pharmacogenetics and Genomics — Vol. 15, no. 11, p. 779-786 (2005)