All Publications

Pages

1. • Journal article

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   Inhibition of the Oxygen Sensor PHD2 Enhances Tissue-Engineered Endochondral Bone Formation.

   Stiers, Pieter-Jan Stegen, Steve van Gastel, Nick[UCL] Van Looveren, Riet Torrekens, Sophie Carmeliet, Geert (2019) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research — Vol. 34, no.2, p. 333-348 (2019)
2. • Journal article

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   Le rôle de la régulation métabolique dans le fonctionnement des cellules du squelette

   van Gastel, Nick[UCL] (2021) Ortho-rhumato — Vol. 19, no. 3, p. 7-11 (2021)
3. • Journal article

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   Endothelial Msx1 transduces hemodynamic changes into an arteriogenic remodeling response

   Vandersmissen, Ine Craps, Sander Depypere, Maarten Coppiello, Giulia van Gastel, Nick[UCL] Maes, Frederik Carmeliet, Gerrt Schrooten, Jan Jones, Elizabeth A.V. Umans, Lieve Devlieger, Roland Koole, Michel Gheysens, Olivier[UCL] Zwijsen, An Aranguren, Xabier L. Luttun, Aernout (2015) Journal of Cell Biology — Vol. 210, no.7, p. 1239-1256 (2015)
4. • Journal article

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   Uncovering the periosteum for skeletal regeneration: The stem cell that lies beneath

   Roberts, Scott J. van Gastel, Nick[UCL] Carmeliet, Geert Luyten, Frank P. (2015) Bone — Vol. 70, no.1, p. 10-18 (2015)
5. • Journal article

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   Metabolic regulation of skeletal cell fate and function in physiology and disease

   van Gastel, Nick[UCL] Carmeliet, Geert (2021) Nature Metabolism — Vol. 3, no.1, p. 11-20 (2021)
6. • Journal article

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   Lipid availability determines fate of skeletal progenitor cells via SOX9

   van Gastel, Nick[UCL] Stegen, Steve Eelen, Guy Schoors, Sandra Carlier, Aurélie Daniëls, Veerle W. Baryawno, Ninib Przybylski, Dariusz Depypere, Maarten Stiers, Pieter-Jan Lambrechts, Dennis Van Looveren, Riet Torrekens, Sophie Sharda, Azeem Agostinis, Patrizia Lambrechts, Diether Maes, Frederik Swinnen, Johan V. Geris, Liesbet Van Oosterwyck, Hans Thienpont, Bernard Carmeliet, Peter Scadden, David T. Carmeliet, Geert (2020) Nature — Vol. 579, no.7797, p. 111-117 (2020)
7. • Journal article

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   An Ectopic Imaging Window for Intravital Imaging of Engineered Bone Tissue

   Stiers, Pieter-Jan van Gastel, Nick[UCL] Moermans, Karen Stockmans, Ingrid Carmeliet, Geert (2018) JBMR Plus — Vol. 2, no.2, p. 92-102 (2018)
8. • Journal article

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   Regulatory elements driving the expression of skeletal lineage reporters differ during bone development and adulthood

   Stiers, Pieter-Jan van Gastel, Nick[UCL] Moermans, Karen Stockmans, Ingrid Carmeliet, Geert (2017) Bone — Vol. 105, no.1, p. 154-162 (2017)
9. • Journal article

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   Young haematopoietic stem cells are picky eaters

   van Gastel, Nick[UCL] Scadden, David T. (2021) Cell Research — Vol. 31, no.4, p. 377-378 (2021)
10. • Journal article

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    Bringing new life to damaged bone: The importance of angiogenesis in bone repair and regeneration

    Stegen, Steve van Gastel, Nick[UCL] Carmeliet, Geert (2015) Bone — Vol. 70, no.1, p. 19-27 (2015)
11. • Journal article

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    Targeting the hypoxic response in bone tissue engineering: A balance between supply and consumption to improve bone regeneration

    Stiers, Pieter-Jan van Gastel, Nick[UCL] Carmeliet, Geert (2016) Molecular and Cellular Endocrinology — Vol. 432, no.1, p. 96-105 (2016)
12. • Journal article

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    Fine-tuning pro-angiogenic effects of cobalt for simultaneous enhancement of vascular endothelial growth factor secretion and implant neovascularization

    Chai, Yoke Chin Freitas Mendes, Luis van Gastel, Nick[UCL] Carmeliet, Geert Luyten, Frank P. (2018) Acta Biomaterialia — Vol. 72, no.1, p. 447-460 (2018)
13. • Journal article

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    Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

    Wang, Yi-Ping Sharda, Azeem Xu, Shuang-Nian van Gastel, Nick[UCL] Man, Cheuk Him Choi, Una Leong, Wei Zhong Li, Xi Scadden, David T. (2021) Cell Metabolism — Vol. 33, no.5, p. 1027-1041.e8 (2021)
14. • Journal article

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    Metabolic perturbations sensitize triple-negative breast cancers to apoptosis induced by BH3 mimetics

    Daniels, Veerle W. Zoeller, Jason J. van Gastel, Nick[UCL] McQueeney, Kelley E. Parvin, Salma Potter, Danielle S. Fell, Geoffrey G. Ferreira, Vinícius G. Yilma, Binyam Gupta, Rajat Spetz, Johan Bhola, Patrick D. Endress, Jennifer E. Harris, Isaac S. Carrilho, Emanuel Sarosiek, Kristopher A. Scadden, David T. Brugge, Joan S. Letai, Anthony (2021) Science Signaling — Vol. 14, no.686, p. eabc7405 (2021)
15. • Journal article

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    The vasculature: a vessel for bone metastasis.

    Raymaekers, Koen Stegen, Steve van Gastel, Nick[UCL] Carmeliet, Geert (2015) BoneKEy reports — Vol. 4, no.1, p. 742 (2015)
16. • Journal article

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    De rol van metabole regulering in het fuctioneren van de skeletcel

    van Gastel, Nick[UCL] (2021) Ortho-rheumato — Vol. 19, no. 3, p. 7-11 (2021)
17. • Journal article

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    Imaging dynamic mTORC1 pathway activity in vivo reveals marked shifts that support time-specific inhibitor therapy in AML

    Oki, Toshihiko Mercier, Francois Kato, Hiroki Jung, Yookyung McDonald, Thomas O. Spencer, Joel A. Mazzola, Michael C. van Gastel, Nick[UCL] Lin, Charles P. Michor, Franziska Kitamura, Toshio Scadden, David T. (2021) Nature Communications — Vol. 12, no.1, p. 245 (2021)
18. • Journal article

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    Analysis of Leukemia Cell Metabolism through Stable Isotope Tracing in Mice.

    van Gastel, Nick[UCL] Spinelli, Jessica B Haigis, Marcia C Scadden, David T (2021) Bio-protocol — Vol. 11, no.19, p. e4171 (2021)
19. • Journal article

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    Induction of a Timed Metabolic Collapse to Overcome Cancer Chemoresistance

    van Gastel, Nick[UCL] Spinelli, Jessica B. Sharda, Azeem Schajnovitz, Amir Baryawno, Ninib Rhee, Catherine Oki, Toshihiko Grace, Eliane Soled, Heather J. Milosevic, Jelena Sykes, David B. Hsu, Peggy P. Vander Heiden, Matthew G. Vidoudez, Charles Trauger, Sunia A. Haigis, Marcia C. Scadden, David T. (2020) Cell Metabolism — Vol. 32, no.3, p. 391-403.e6 (2020)
20. • Journal article

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    Highly proliferative primitive fetal liver hematopoietic stem cells are fueled by oxidative metabolic pathways.

    Manesia, Javed K Xu, Zhuofei Broekaert, Dorien Boon, Ruben van Vliet, Alex Eelen, Guy Vanwelden, Thomas Stegen, Steve van Gastel, Nick[UCL] Pascual-Montano, Alberto Fendt, Sarah-Maria Carmeliet, Geert Carmeliet, Peter Khurana, Satish Verfaillie, Catherine M. (2015) Stem cell research — Vol. 15, no.3, p. 715-721 (2015)
21. • Journal article

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    Engineering vascularized bone: Osteogenic and proangiogenic potential of murine periosteal cells

    van Gastel, Nick[UCL] Torrekens, Sophie Roberts, Scott J Moermans, Karen Schrooten, Jan Carmeliet, Peter Luttun, Aernout Luyten, Frank P Carmeliet, Geert (2012) Stem Cells — Vol. 30, no.11, p. 2460-2471 (2012)
22. • Journal article

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    Nestin-GFP transgene labels skeletal progenitors in the periosteum

    Tournaire, Guillaume Stegen, Steve Giacomini, Greta Stockmans, Ingrid Moermans, Karen Carmeliet, Geert van Gastel, Nick[UCL] (2020) Bone — Vol. 133, no.1, p. 115259 (2020)
23. • Journal article

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    Size Does Matter: An Integrative In Vivo-In Silico Approach for the Treatment of Critical Size Bone Defects

    Carlier, Aurélie van Gastel, Nick[UCL] Geris, Liesbet Carmeliet, Geert Van Oosterwyck, Hans (2014) PLoS Computational Biology — Vol. 10, no.11, p. e1003888 (2014)
24. • Journal article

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    C9orf72 suppresses systemic and neural inflammation induced by gut bacteria

    Burberry, Aaron Wells, Michael F. Limone, Francesco Couto, Alexander Smith, Kevin S. Keaney, James Gillet, Gaëlle van Gastel, Nick[UCL] Wang, Jin-Yuan Pietilainen, Olli Qian, Menglu Eggan, Pierce Cantrell, Christopher Mok, Joanie Kadiu, Irena Scadden, David T. Eggan, Kevin (2020) Nature — Vol. 582, no.7810, p. 89-94 (2020)
25. • Journal article

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    Expansion of murine periosteal progenitor cells with fibroblast growth factor 2 reveals an intrinsic endochondral ossification program mediated by bone morphogenetic protein 2

    van Gastel, Nick[UCL] Stegen, Steve Stockmans, Ingrid Moermans, Karen Schrooten, Jan Graf, Daniel Luyten, Frank P. Carmeliet, Geert (2014) Stem Cells — Vol. 32, no.9, p. 2407-2418 (2014)

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