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All Publications

Displaying 18 results.
    • Journal article
    The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.
    Lloberas, Nuria Elens, Laure[UCL] Llaudó, Ines Padullés, Ariadna van Gelder, Teun Hesselink, Dennis A Colom, Helena Andreu, Franc Torras, Joan Bestard, Oriol Cruzado, Josep M Gil-Vernet, Salvador van Schaik, Ron Grinyó, Josep M (2017) Pharmacogenetics and Genomics — Vol. 27, p. 313-322 (2017)
    • Journal article
    A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients.
    Elens, Laure[UCL] Bouamar, Rachida Hesselink, Dennis A Haufroid, Vincent[UCL] van der Heiden, Ilse P van Gelder, Teun van Schaik, Ron H N (2011) Clinical Chemistry : international journal of molecular diagnostics and laboratory medicine — Vol. 57, no. 11, p. 1574-83 (2011)
    • Journal article
    Barcelona Consensus on Biomarker-Based Immunosuppressive Drugs Management in Solid Organ Transplantation
    Brunet, Mercè Shipkova, Maria van Gelder, Teun Wieland, Eberhard Sommerer, Claudia Budde, Klemens Haufroid, Vincent[UCL] Christians, Uwe López-Hoyos, Marcos Barten, Markus J Bergan, Stein Picard, Nicolas Millán López, Olga Marquet, Pierre Hesselink, Dennis A Noceti, Ofelia Pawinski, Tomasz Wallemacq, Pierre[UCL] Oellerich, Michael (2016) Therapeutic Drug Monitoring — Vol. 38, no.Suppl 1, p. S1-S20 (2016)
    • Journal article
    Pharmacogenetic associations with cytochrome P450 in antiretroviral therapy: what does the future hold?
    Stillemans, Gabriel[UCL] Belkhir, Leïla[UCL] Hesselink, Dennis A Haufroid, Vincent[UCL] Elens, Laure[UCL] (2018) Expert opinion on drug metabolism & toxicology — Vol. 14, no. 6, p. 601-611 (2018)
    • Journal article
    CYP3A4*22: promising newly identified CYP3A4 variant allele for personalizing pharmacotherapy
    Elens, Laure[UCL] van Gelder, Teun Hesselink, Dennis A Haufroid, Vincent[UCL] van Schaik, Ron H N (2013) Pharmacogenomics — Vol. 14, no. 1, p. 47-62 (2013)
    • Journal article
    The new CYP3A4 intron 6 C>T polymorphism (CYP3A4*22) is associated with an increased risk of delayed graft function and worse renal function in cyclosporine-treated kidney transplant patients.
    Elens, Laure Bouamar, Rachida Hesselink, Dennis A Haufroid, Vincent van Gelder, Teun van Schaik, Ron H N (2012) Pharmacogenetics and genomics — Vol. 22, no.5, p. 373-80 (2012)
    • Journal article
    A New CYP3A5*3 and CYP3A4*22 Cluster Influencing Tacrolimus Target Concentrations: A Population Approach.
    Andreu, Franc Colom, Helena Elens, Laure[UCL] van Gelder, Teun van Schaik, Ronald H N Hesselink, Dennis A Bestard, Oriol Torras, Joan Cruzado, Josep M Grinyó, Josep M Lloberas, Nuria (2017) Clinical Pharmacokinetics — Vol. 56, p. 963-975 (2017)
    • Journal article
    Measuring Intracellular Concentrations of Calcineurin Inhibitors: Expert Consensus from the International Association of Therapeutic Drug Monitoring and Clinical Toxicology Expert Panel.
    Lemaitre, Florian Vethe, Nils T D'Avolio, Antonio Tron, Camille Robertsen, Ida De Winter, Brenda Denicolo, Amedeo Koch, Birgit C P Venkataramanan, Raman Van Gelder, Teun Brunet, Mercè Bergan, Stein Hesselink, Dennis A Wallemacq, Pierre[UCL] (2020) Therapeutic drug monitoring — Vol. 42, no.5, p. 665-670 (2020)
    • Journal article
    Therapeutic Drug Monitoring of Everolimus: A Consensus Report.
    Shipkova, Maria Hesselink, Dennis A Holt, David W Billaud, Eliane M van Gelder, Teun Kunicki, Paweł K Brunet, Mercè Budde, Klemens Barten, Markus J De Simone, Paolo Wieland, Eberhard López, Olga Millán Masuda, Satohiro Seger, Christoph Picard, Nicolas Oellerich, Michael Langman, Loralie J Wallemacq, Pierre[UCL] Morris, Raymond G Thompson, Carol Marquet, Pierre (2016) Therapeutic Drug Monitoring — Vol. 38, no.2, p. 143-169 (2016)
    • Journal article
    Pharmacogenetic Biomarkers Predictive of the Pharmacokinetics and Pharmacodynamics of Immunosuppressive Drugs.
    Picard, Nicolas Bergan, Stein Marquet, Pierre van Gelder, Teun Wallemacq, Pierre[UCL] Hesselink, Dennis A Haufroid, Vincent[UCL] (2016) Therapeutic Drug Monitoring — Vol. 38, no.Suppl 1, p. S57-S69 (2016)
    • Journal article
    Mycophenolic acid-related anemia and leucopenia in renal transplant recipients are related to genetic polymorphisms in CYP2C8.
    Bouamar, Rachida Elens, Laure[UCL] Shuker, Nauras van Schaik, Ron H N Weimar, Willem Hesselink, Dennis A van Gelder, Teun (2012) Transplantation — Vol. 93, no.10, p. e39-40; author reply e41-2 (2012)
    • Journal article
    Therapeutic Drug Monitoring of Tacrolimus-Personalized Therapy: Second Consensus Report.
    Brunet, Mercè van Gelder, Teun Åsberg, Anders Haufroid, Vincent[UCL] Hesselink, Dennis A Langman, Loralie Lemaitre, Florian Marquet, Pierre Seger, Christoph Shipkova, Maria Vinks, Alexander Wallemacq, Pierre[UCL] Wieland, Eberhard Woillard, Jean Baptiste Barten, Markus J Budde, Klemens Colom, Helena Dieterlen, Maja-Theresa Elens, Laure[UCL] Johnson-Davis, Kamisha L Kunicki, Paweł K MacPhee, Iain Masuda, Satohiro Mathew, Binu S Millán, Olga Mizuno, Tomoyuki Moes, Dirk-Jan A R Monchaud, Caroline Noceti, Ofelia Pawinski, Tomasz Picard, Nicolas van Schaik, Ron Sommerer, Claudia Vethe, Nils Tore de Winter, Brenda Christians, Uwe Bergan, Stein (2019) Therapeutic drug monitoring — Vol. 41, no.3, p. 261-307 (2019)
    • Journal article
    Pharmacogenetics in kidney transplantation: recent updates and potential clinical applications
    Elens, Laure[UCL] Hesselink, Dennis A van Schaik, Ron H N van Gelder, Teun (2012) Molecular Diagnosis and Therapy — Vol. 16, no. 6, p. 331-345 (2012)
    • Journal article
    Detection of a rare CYP3A4 variant in a transplant patient characterized by a tacrolimus poor metabolizer phenotype.
    Lloberas, Nuria Hesselink, Dennis A van Schaik, Ron Hn Grinyò, Josep M Colom, Helena Gelder, Teun van Elens, Laure[UCL] (2018) Pharmacogenomics — Vol. 19, no.4, p. 305-310 (2018)
    • Journal article
    Impact of POR*28 on the pharmacokinetics of tacrolimus and cyclosporine A in renal transplant patients
    Elens, Laure[UCL] Hesselink, Dennis A Bouamar, Rachida Budde, Klemens de Fijter, Johannes W De Meyer, Martine[UCL] Mourad, Michel[UCL] Kuypers, Dirk R J Haufroid, Vincent[UCL] van Gelder, Teun van Schaik, Ron H N (2014) Therapeutic Drug Monitoring — Vol. 36, no. 1, p. 71-79 (2014)
    • Journal article
    Tacrolimus Updated Guidelines through popPK Modeling: How to Benefit More from CYP3A Pre-emptive Genotyping Prior to Kidney Transplantation.
    Woillard, Jean-Baptiste Mourad, Michel[UCL] Neely, Michael Capron, Arnaud[UCL] van Schaik, Ron H van Gelder, Teun Lloberas, Nuria Hesselink, Dennis A Marquet, Pierre Haufroid, Vincent[UCL] Elens, Laure[UCL] (2017) Frontiers in Pharmacology — Vol. 8, p. 358 [1-14] (2017)
    • Journal article
    Single-nucleotide polymorphisms in P450 oxidoreductase and peroxisome proliferator-activated receptor-α are associated with the development of new-onset diabetes after transplantation in kidney transplant recipients treated with tacrolimus.
    Elens, Laure[UCL] Sombogaard, Ferdi Hesselink, Dennis A van Schaik, Ron H N van Gelder, Teun (2013) Pharmacogenetics and Genomics — Vol. 23, no.12, p. 649-657 (2013)
    • Journal article
    The CYP3A4*22 allele affects the predictive value of a pharmacogenetic algorithm predicting tacrolimus predose concentrations
    Elens, Laure[UCL] Hesselink, Dennis A van Schaik, Ron H N van Gelder, Teun (2013) British Journal of Clinical Pharmacology — Vol. 75, no. 6, p. 1545-1547 (2013)