All Publications

Pages

1. • Journal article

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   CYP3A5 and ABCB1 polymorphisms and tacrolimus pharmacokinetics in renal transplant candidates: guidelines from an experimental study.

   Haufroid, Vincent[UCL] De Meyer, Martine[UCL] Wallemacq, Pierre[UCL] Van Kerckhove, Valérie[UCL] Elens, Laure[UCL] Eddour, D C Malaise, Jacques Lison, Dominique[UCL] Mourad, Michel[UCL] (2006) American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons — Vol. 6, no. 11, p. 2706-13 (2006)
2. • Journal article

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   The combination of CYP3A4*22 and CYP3A5*3 single-nucleotide polymorphisms determines tacrolimus dose requirement after kidney transplantation.

   Lloberas, Nuria Elens, Laure[UCL] Llaudó, Ines Padullés, Ariadna van Gelder, Teun Hesselink, Dennis A Colom, Helena Andreu, Franc Torras, Joan Bestard, Oriol Cruzado, Josep M Gil-Vernet, Salvador van Schaik, Ron Grinyó, Josep M (2017) Pharmacogenetics and Genomics — Vol. 27, p. 313-322 (2017)
3. • Journal article

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   Antipsychotic polypharmacy and clozapine prescribing patterns: evolution and correlates before and after a psychiatric hospitalisation

   Lagreula, Juliette[UCL] de Timary, Philippe[UCL] Elens, Laure[UCL] Dalleur, Olivia[UCL] (2022) Therapeutic advances in psychopharmacology — Vol. 12, p. [1-12] (2022)
4. • Journal article

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   A new functional CYP3A4 intron 6 polymorphism significantly affects tacrolimus pharmacokinetics in kidney transplant recipients.

   Elens, Laure[UCL] Bouamar, Rachida Hesselink, Dennis A Haufroid, Vincent[UCL] van der Heiden, Ilse P van Gelder, Teun van Schaik, Ron H N (2011) Clinical Chemistry : international journal of molecular diagnostics and laboratory medicine — Vol. 57, no. 11, p. 1574-83 (2011)
5. • Journal article

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   CYP3A4∗22 Genotyping in Clinical Practice: Ready for Implementation?

   Mulder, Tessa A. M. van Eerden, Ruben A. G. de With, Mirjam Elens, Laure[UCL] Hesselink, Dennis A. Matic, Maja Bins, Sander Mathijssen, Ron H. J. van Schaik, Ron H. N. (2021) Frontiers in Genetics — Vol. 12, no. 12, p. 711943 (2021)
6. • Speech

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   Companion diagnostics: Clinical significance of Pharmacogenetics, the concept of personalized therapy

   Elens, Laure[UCL] (2013) xSample Luminex Congress — Rotterdam, The Netherlands
7. • Journal article

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   Influence of donor-recipient CYP3A4/5 genotypes, age and fluconazole on tacrolimus pharmacokinetics in pediatric liver transplantation: a population approach

   Guy-Viterbo, Vanessa[UCL] Baudet, Henry Elens, Laure[UCL] Haufroid, Vincent[UCL] Lacaille, Florence Girard, Muriel Debray, Dominique Chardot, Christophe Reding, Raymond[UCL] Wallemacq, Pierre[UCL] Musuamba, Flora (2014) Pharmacogenomics — Vol. 15, no. 9, p. 1207-1221 (2014)
8. • Journal article

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   Personalized Therapy for Mycophenolate: Consensus Report by the International Association of Therapeutic Drug Monitoring and Clinical Toxicology

   Bergan, Stein Brunet, Mercè Hesselink, Dennis A. Johnson-Davis, Kamisha L. Kunicki, Paweł K. Lemaitre, Florian Marquet, Pierre Molinaro, Mariadelfina Noceti, Ofelia Pattanaik, Smita Pawinski, Tomasz Seger, Christoph Shipkova, Maria Swen, Jesse J. van Gelder, Teun Venkataramanan, Raman Wieland, Eberhard Woillard, Jean-Baptiste Zwart, Tom C. Barten, Markus J. Budde, Klemens Dieterlen, Maja-Theresa Elens, Laure[UCL] Haufroid, Vincent[UCL] Masuda, Satohiro Millan, Olga Mizuno, Tomoyuki Moes, Dirk J. A. R. Oellerich, Michael Picard, Nicolas Salzmann, Linda Tönshoff, Burkhard van Schaik, Ron H. N. Vethe, Nils Tore Vinks, Alexander A. Wallemacq, Pierre[UCL] Åsberg, Anders Langman, Loralie J. (2021) Therapeutic drug monitoring — Vol. 43, no. 2, p. 150-200 (2021)
9. • Journal article

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   CYP3A4 intron 6 C>T SNP (CYP3A4*22) encodes lower CYP3A4 activity in cancer patients, as measured with probes midazolam and erythromycin.

   Elens, Laure[UCL] Nieuweboer, Annemieke Clarke, Stephen J Charles, Kellie A de Graan, Anne-Joy Haufroid, Vincent Mathijssen, Ron H J van Schaik, Ron H N (2013) Pharmacogenomics — Vol. 14, no.2, p. 137-149 (2013)
10. • Journal article

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    Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin.

    Elens, Laure[UCL] Nieuweboer, Annemieke J M Clarke, Stephen J Charles, Kellie A de Graan, Anne-Joy M Haufroid, Vincent[UCL] van Gelder, Teun Mathijssen, Ron H J van Schaik, Ron H N (2013) Pharmacogenetics and Genomics — Vol. 23, no.3, p. 148-155 (2013)
11. • Journal article

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    Functional defect caused by the 4544G>A SNP in ABCC2 : potential impact for drug cellular disposition.

    Elens, Laure[UCL] Tyteca, Donatienne[UCL] Panin, Nadtha[UCL] Courtoy, Pierre J.[UCL] Lison, Dominique[UCL] Demoulin, Jean-Baptiste[UCL] Haufroid, Vincent[UCL] (2011) Pharmacogenetics and Genomics — Vol. 21, no. 12, p. 884-893 (2011)
12. • Journal article

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    Population Pharmacokinetics of Temocillin Administered by Continuous Infusion in Patients with Septic Shock Associated with Intra-Abdominal Infection and Ascitic Fluid Effusion

    Ngougni Pokem, Perrin[UCL] Wittebole, Xavier[UCL] Collienne, Christine[UCL] Rodriguez-Villalobos, Hector[UCL] Tulkens, Paul M.[UCL] Elens, Laure[UCL] Van Bambeke, Françoise[UCL] Laterre, Pierre-François[UCL] (2022) Antibiotics — Vol. 11, no. 7, p. 898 [1-19] (2022)
13. • Journal article

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    Pharmacogenetic associations with cytochrome P450 in antiretroviral therapy: what does the future hold?

    Stillemans, Gabriel[UCL] Belkhir, Leïla[UCL] Hesselink, Dennis A Haufroid, Vincent[UCL] Elens, Laure[UCL] (2018) Expert opinion on drug metabolism & toxicology — Vol. 14, no. 6, p. 601-611 (2018)
14. • Journal article

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    Clinical implementation of pharmacogenetics in kidney transplantation: Calcineurin inhibitors in the starting blocks

    Elens, Laure[UCL] Bouamar, Rachida Shuker, Nauras Hesselink, Dennis A. Van Gelder, Teun Van Schaik, Ron H. N. (2014) British Journal of Clinical Pharmacology — Vol. 77, no. 4, p. 715-728 (2014)
15. • Journal article

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    Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines

    Sennesael, Anne-Laure[UCL] Panin, Nadtha[UCL] Vancraeynest, Christelle Pochet, Lionel Spinewine, Anne[UCL] Haufroid, Vincent[UCL] Elens, Laure[UCL] (2018) Scientific Reports — Vol. 8, no. 1, p. 10514 [1-6] (2018)
16. • Journal article

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    Optimal sampling strategies for darunavir and external validation of the underlying population pharmacokinetic model

    Stillemans, Gabriel[UCL] Belkhir, Leïla[UCL] Vandercam, Bernard[UCL] Vincent, Anne[UCL] Haufroid, Vincent[UCL] Elens, Laure[UCL] (2021) European Journal of Clinical Pharmacology — Vol. 77, no. 4, p. 607-616 (2021)
17. • Journal article

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    Lack of association of the P450 oxidoreductase *28 single nucleotide polymorphism with the lipid-lowering effect of statins in hypercholesterolemic patients

    Ragia, Georgia Kolovou, Vana Tavridou, Anna Elens, Laure[UCL] Tselepis, Alexandros D. Elisaf, Moses Van Schaik, Ron H. N. Kolovou, Genovefa Manolopoulos, Vangelis G. (2014) Molecular Diagnosis and Therapy — Vol. 18, no. 3, p. 323-331 (2014)
18. • Speech

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    Impact of POR*28 on the clinical pharmacokinetics of CYP3A phenotyping probes midazolam and erythromycin

    Elens, Laure[UCL] (2013) 13th International Congress of Therapeutic Drug Monitoring & Clinical Toxicology (IATDMCT) — Salt Lake city, USA
19. • Journal article

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    The CYP3A4*22 C>T single nucleotide polymorphism is associated with reduced midazolam and tacrolimus clearance in stable renal allograft recipients.

    de Jonge, H. Elens, Laure[UCL] de Loor, H. van Schaik, R. H. Kuypers, D. R. J. (2015) The Pharmacogenomics Journal — Vol. 15, no. 2, p. 144-152 (2015)
20. • Journal article

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    SLC22A1 /OCT1 genotype affects O-desmethyltramadol exposure in new-born infants.

    Matic, Maja de Wildt, Saskia N Elens, Laure de Hoon, Jan N Annaert, Pieter Tibboel, Dick van Schaik, Ron Hn Allegaert, Karel (2016) Therapeutic Drug Monitoring — Vol. EPub, no.AOP, p. 1 (2016)
21. • Journal article

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    The role of pharmacogenetics in the disposition of and response to tacrolimus in solid organ transplantation

    Hesselink, Dennis A. Bouamar, Rachida Elens, Laure[UCL] Van Schaik, Ron H. N. Van Gelder, Teun (2014) Clinical Pharmacokinetics — Vol. 53, no. 2, p. 123-139 (2014)
22. • Speech

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    Impact of UGT1A1*28 Polymorphism on Raltegravir Metabolism

    Belkhir, Leïla[UCL] Elens, Laure[UCL] Pauly, C. Devaux, C. Schneider, S. Yombi, Jean Cyr[UCL] Vincent, Anne[UCL] Vandercam, Bernard[UCL] Haufroid, Vincent[UCL] (2015) 15th European AIDS Conference — (Spain) Barcelona
23. • Speech

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    The new CYP3A4 intron 6 SNP significantly affects drug metabolism of midazolam, erythromycin and tacrolimus

    Elens, Laure[UCL] (2012) 16th Molecular medicine Day — Rotterdam, The Netherlands
24. • Speech

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    Pharmacogenetics of Opioids

    Elens, Laure[UCL] (2015) 14th International Congress of Therapeutic Drug monitoring and Clinical Toxicology (IATDMCT) — Rotterdam, The Netherlands
25. • Speech

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    Validation and clinical application of a high performance liquid chromatography tandem mass spectrometry (LC-MS/MS) method with isotopic dilution for the quantitative determination of 10 anti-retrovirals in human peripheral blood mononuclear cells

    Elens, Laure[UCL] (2008) Belgian and Luxembourg Society of Toxicology (BLT) — Brussels

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