Bodéus, Monique
[UCL]
Goubau, Patrick
[UCL]
Laffineur, K.
[UCL]
Kabamba-Mukadi, Benoît
[UCL]
Hubinont, Corinne
[UCL]
Bernard, Pierre
[UCL]
OBJECTIVE: The objective of this study was to study the prevalence of herpes simplex virus (HSV) type 2 in pregnant women in Belgium. STUDY DESIGN: The serum of 1000 consecutive women was collected. HSV-1 and HSV-2 control sera were added to the study. HSV-2 antibodies were tested with the HerpeSelect 2 enzyme-linked immunosorbent assay (ELISA; Focus) based on the use of the recombinant gG-2 antigen. RESULTS: The 21 HSV-2 control subjects were positive. Among the HSV-1 control subjects, 18 were negative and 4 were positive. Among the pregnant women, 80.3% were negative, 1.5% had equivocal results, and 18.2% were positive. No statistical difference was observed according to the origin (European or African) of the women. CONCLUSIONS: The results obtained with the control sera indicate a high sensitivity of the Focus ELISA, as well as a capacity to discriminate between HSV-1/HSV-2 infection. The HSV-2 prevalence in the studied population raises the question of the possible benefit of a specific preventive program in pregnant women.
Bibliographic reference |
Bodéus, Monique ; Goubau, Patrick ; Laffineur, K. ; Kabamba-Mukadi, Benoît ; Hubinont, Corinne ; et. al. Seroepidemiology of herpes simplex type 2 in pregnant women in Belgium.. In: Sexually Transmitted Diseases, Vol. 31, no. 5, p. 297-300 (2004) |
Permanent URL |
http://hdl.handle.net/2078.1/9817 |