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Wild-type and mutant p53 proteins interact with mitochondrial caspase-3.

Bibliographic reference Frank, Amanda K ; Pietsch, E Christine ; Dumont, Patrick R. ; Tao, Joy ; Murphy, Maureen E. Wild-type and mutant p53 proteins interact with mitochondrial caspase-3.. In: Cancer biology & therapy, Vol. 11, no. 8, p. 740-745 (2011)
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  1. Nicholson DW, Caspase structure, proteolytic substrates and function during apoptotic cell death, 10.1038/sj.cdd.4400598
  2. Stennicke Henning R., Salvesen Guy S., Properties of the caspases, 10.1016/s0167-4838(98)00133-2
  3. Taylor Rebecca C., Cullen Sean P., Martin Seamus J., Apoptosis: controlled demolition at the cellular level, 10.1038/nrm2312
  4. Zhivotovsky Boris, Samali Afshin, Gahm Annie, Orrenius Sten, Caspases: their intracellular localization and translocation during apoptosis, 10.1038/sj.cdd.4400536
  5. Samali Afshin, Zhivotovsky Boris, Jones Dean P, Orrenius Sten, Detection of pro-caspase-3 in cytosol and mitochondria of various tissues, 10.1016/s0014-5793(98)00740-6
  6. Mancini Marie, Nicholson Donald W., Roy Sophie, Thornberry Nancy A., Peterson Erin P., Casciola-Rosen Livia A., Rosen Antony, The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling, 10.1083/jcb.140.6.1485
  7. Samali A., Presence of a pre-apoptotic complex of pro-caspase-3, Hsp60 and Hsp10 in the mitochondrial fraction of Jurkat cells, 10.1093/emboj/18.8.2040
  8. Levine Arnold J, p53, the Cellular Gatekeeper for Growth and Division, 10.1016/s0092-8674(00)81871-1
  9. Mihara Motohiro, Erster Susan, Zaika Alexander, Petrenko Oleksi, Chittenden Thomas, Pancoska Petr, Moll Ute M., p53 Has a Direct Apoptogenic Role at the Mitochondria, 10.1016/s1097-2765(03)00050-9
  10. Chipuk J. E., Direct Activation of Bax by p53 Mediates Mitochondrial Membrane Permeabilization and Apoptosis, 10.1126/science.1092734
  11. Leu J. I-Ju, Dumont Patrick, Hafey Michael, Murphy Maureen E., George Donna L., Mitochondrial p53 activates Bak and causes disruption of a Bak–Mcl1 complex, 10.1038/ncb1123
  12. Pietsch E. Christine, Perchiniak Erin, Canutescu Adrian A., Wang Guoli, Dunbrack Roland L., Murphy Maureen E., Oligomerization of BAK by p53 Utilizes Conserved Residues of the p53 DNA Binding Domain, 10.1074/jbc.m710539200
  13. Cho Y, Gorina S, Jeffrey P., Pavletich N., Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations, 10.1126/science.8023157
  14. Hollstein M, Sidransky D, Vogelstein B, Harris C., p53 mutations in human cancers, 10.1126/science.1905840
  15. Tomita York, Marchenko Natasha, Erster Susan, Nemajerova Alice, Dehner Alexander, Klein Christian, Pan Hongguang, Kessler Horst, Pancoska Petr, Moll Ute M., WT p53, but Not Tumor-derived Mutants, Bind to Bcl2 via the DNA Binding Domain and Induce Mitochondrial Permeabilization, 10.1074/jbc.m507611200
  16. Sayan Berna S., Sayan A. Emre, Knight Richard A., Melino Gerry, Cohen Gerald M., p53 Is Cleaved by Caspases Generating Fragments Localizing to Mitochondria, 10.1074/jbc.m512467200
  17. Zambetti GP, FASEB J, 7, 855 (1993)
  18. Marin Maria Carmen, Jost Christine A., Brooks Louise A., Irwin Meredith S., O'Nions Jenny, Tidy John A., James Nick, McGregor Jane M., Harwood Catherine A., Yulug Isik G., Vousden Karen H., Allday Martin J., Gusterson Barry, Ikawa Shuntaro, Hinds Philip W., Crook Tim, Kaelin William G., A common polymorphism acts as an intragenic modifier of mutant p53 behaviour, 10.1038/75586
  19. Song Hoseok, Hollstein Monica, Xu Yang, p53 gain-of-function cancer mutants induce genetic instability by inactivating ATM, 10.1038/ncb1571
  20. Pimkina Julia, Humbey Olivier, Zilfou Jack T., Jarnik Michal, Murphy Maureen E., ARF Induces Autophagy by Virtue of Interaction with Bcl-xl, 10.1074/jbc.m804705200