User menu

Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes.

Bibliographic reference Tinton, S A ; Buc Calderon, Pedro. Hypoxia increases the association of 4E-binding protein 1 with the initiation factor 4E in isolated rat hepatocytes.. In: FEBS letters, Vol. 446, no. 1, p. 55-9 (1999)
Permanent URL
  1. Hershey John W. B., Translational Control in Mammalian Cells, 10.1146/
  2. Kleijn Miranda, Scheper Gert C., Voorma Harry O., Thomas Adri A. M., Regulation of translation initiation factors by signal transduction, 10.1046/j.1432-1327.1998.2530531.x
  3. Sonenberg Nahum, Gingras Anne-Claude, The mRNA 5′ cap-binding protein eIF4E and control of cell growth, 10.1016/s0955-0674(98)80150-6
  4. Haghighat, EMBO J., 14, 5701 (1995)
  5. Pause Arnim, Belsham Graham J., Gingras Anne-Claude, Donzé Olivier, Lin Tai-An, Lawrence John C., Sonenberg Nahum, Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function, 10.1038/371762a0
  6. Lin T., Kong X, Haystead T., Pause A, Belsham G, Sonenberg N, Lawrence J., PHAS-I as a link between mitogen-activated protein kinase and translation initiation, 10.1126/science.7939721
  7. Lawrence J, PHAS/4E-BPs as regulators of mRNA translation and cell proliferation, 10.1016/s0968-0004(97)01101-8
  8. Hara Kenta, Yonezawa Kazuyoshi, Weng Qing-Ping, Kozlowski Mark T., Belham Christopher, Avruch Joseph, Amino Acid Sufficiency and mTOR Regulate p70 S6 Kinase and eIF-4E BP1 through a Common Effector Mechanism, 10.1074/jbc.273.23.14484
  9. Freigenblum, Mol. Cell. Biol., 16, 5450 (1996)
  10. Vries Robert G. J., Flynn Andrea, Patel Jashmin C., Wang Xuemin, Denton Richard M., Proud Christopher G., Heat Shock Increases the Association of Binding Protein-1 with Initiation Factor 4E, 10.1074/jbc.272.52.32779
  11. Wang, Biochem. J., 334, 261 (1998)
  12. Proud, Biochem. J., 328, 329 (1997)
  13. Kimball, Am. J. Physiol., 272, C754 (1997)
  14. Graves L. M., Bornfeldt K. E., Argast G. M., Krebs E. G., Kong X., Lin T. A., Lawrence J. C., cAMP- and rapamycin-sensitive regulation of the association of eukaryotic initiation factor 4E and the translational regulator PHAS-I in aortic smooth muscle cells., 10.1073/pnas.92.16.7222
  15. Burnett P. E., Barrow R. K., Cohen N. A., Snyder S. H., Sabatini D. M., RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1, 10.1073/pnas.95.4.1432
  16. Diggle, Biochem. J., 316, 447 (1996)
  17. Bunn, Physiol. Rev., 76, 839 (1996)
  18. Hochachka P. W., Buck L. T., Doll C. J., Land S. C., Unifying theory of hypoxia tolerance: molecular/metabolic defense and rescue mechanisms for surviving oxygen lack., 10.1073/pnas.93.18.9493
  19. Lefebvre V.H.L., Vansteenbrugge M., Beckers V., Roberfroid M., Buccalderon P., Adenine Nucleotides and Inhibition of Protein Synthesis in Isolated Hepatocytes Incubated under Different pO2 Levels, 10.1006/abbi.1993.1357
  20. Tinton Sandrine, Tran-Nguyen Qui-Nhi, Buc-Calderon Pedro, Role of Protein-Phosphorylation Events in the Anoxia Signal-Transduction Pathway Leading to the Inhibition of Total Protein Synthesis in Isolated Hepatocytes, 10.1111/j.1432-1033.1997.t01-1-00121.x
  21. Tinton, Biochem. J., 310, 893 (1995)
  22. LAEMMLI U. K., Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4, 10.1038/227680a0
  23. Seglen, Biochim. Biophys. Acta, 422, 391 (1976)
  24. Lowry, J. Biol. Chem., 193, 265 (1951)
  25. Morley Simon J., McKendrick Linda, Involvement of Stress-activated Protein Kinase and p38/RK Mitogen-activated Protein Kinase Signaling Pathways in the Enhanced Phosphorylation of Initiation Factor 4E in NIH 3T3 Cells, 10.1074/jbc.272.28.17887
  26. Gingras A.-C., Kennedy S. G., O'Leary M. A., Sonenberg N., Hay N., 4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway, 10.1101/gad.12.4.502
  27. Brown Eric J, Schreiber Stuart L, A Signaling Pathway to Translational Control, 10.1016/s0092-8674(00)80125-7
  28. Brunn G. J., Phosphorylation of the Translational Repressor PHAS-I by the Mammalian Target of Rapamycin, 10.1126/science.277.5322.99
  29. von Manteuffel, Mol. Cell. Biol., 17, 5426 (1997)
  30. Kawasome H., Papst P., Webb S., Keller G. M., Johnson G. L., Gelfand E. W., Terada N., Targeted disruption of p70s6k defines its role in protein synthesis and rapamycin sensitivity, 10.1073/pnas.95.9.5033
  31. Hara Kenta, Yonezawa Kazuyoshi, Kozlowski Mark T., Sugimoto Tadanori, Andrabi Khurshid, Weng Qing-Ping, Kasuga Masato, Nishimoto Ikuo, Avruch Joseph, Regulation of eIF-4E BP1 Phosphorylation by mTOR, 10.1074/jbc.272.42.26457
  32. Mendez, Mol. Cell. Biol., 16, 2857 (1996)
  33. Jefferies H. B.J., Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k, 10.1093/emboj/16.12.3693
  34. Hu, J. Neurosci., 13, 1830 (1993)