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Straightforward hetero Diels-Alder reactions of nitroso dienophiles by microreactor technology

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Monbaliu, Jean-Christophe M. R. [Univ Ghent] Cukalovic, Ana [Univ Ghent] Marchand-Brynaert, Jacqueline [UCL] Stevens, Christian V. [Univ Ghent]

The hetero Diels-Alder reactions of 2-nitrosotoluene and some representative acylnitrosodienophiles with a selected set of 1,3-dienes were studied under microflow conditions. The main assets of the technology, that is, an accurate control of the reaction parameters and continuous operating, led to an increased efficiency of this reaction. (C) 2010 Elsevier Ltd. All rights reserved.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 2010
Language Anglais
Journal information "Tetrahedron letters" - Vol. 51, no. 44, p. 5830-5833 (2010)
Peer reviewed yes
Publisher PERGAMON-ELSEVIER SCIENCE LTD
issn 0040-4039
Publication status Publié
Affiliations Univ Ghent - SynBioC Res Grp, Dept Sustainable Organ Chem & Technol, Fac Biosci Engn
UCL - SST/IMCN/MOST - Molecules, Solids and Reactivity
Keywords Microreactor ; Hetero Diels-Alder reaction ; Nitroso dienophiles ; Flowconditions
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Bibliographic reference Monbaliu, Jean-Christophe M. R. ; Cukalovic, Ana ; Marchand-Brynaert, Jacqueline ; Stevens, Christian V.. Straightforward hetero Diels-Alder reactions of nitroso dienophiles by microreactor technology . In: Tetrahedron letters, Vol. 51, no. 44, p. 5830-5833 (2010)
Permanent URL http://hdl.handle.net/2078.1/78185