User menu

Isolation and Mass-spectrometric Identification of Gitoxin Metabolites Excreted in Bile

Bibliographic reference Kadima, LN. ; Lhoëst, Georges ; Lesne, Michel. Isolation and Mass-spectrometric Identification of Gitoxin Metabolites Excreted in Bile. In: European Journal of Drug Metabolism and Pharmacokinetics, Vol. 7, no. 2, p. 111-117 (1982)
Permanent URL
  1. Nuki B., Kumada S. and Kurose J. (1955): Pharmacological study on gitoxin, Igaku Kendyu25, 403–410.
  2. Haustein K.-O., Hauptmann J., Studies on Cardioactive Steroids, 10.1159/000136482
  3. Haustein K.O., Graumann G. and Stephan B. (1975): Cardioactive Steroids III. Characterization of different glycosides by their effects on contractibility and rythmicity at different extracellular potassium concentrations, Acta biol. med. germ.34, 1065–1073.
  4. Dolphen R. and Lesne M. (1980): Uptake and Pharmacological effect of gitoxin and gitaloxin in rat and guineapig perfused hearts. Comparison with digitoxin and digoxin, Arzneim-Forsch. Drug Res.30, 614–618.
  5. Lesne M. (1978): Pharmacological reevaluation of gitoxin in man, Int. J. Clin. Pharmacol. Biopharm.16, 456–459.
  6. Lesne M., van Ypersele Ch. and Vandenbroecke J.M. (1977): Etude préliminaire de la pharmacocinétique de la gitoxine dans l’insuffisance rénale, J. Pharmacol., Paris8, 552.
  7. Kadima L.N. and Lesne M. (1980): Studies on the pharmacokinetics and the metabolism of gitoxin in the guineapig I. Disposition kinetics following an i.v. bolus H3-gitoxin, Arch. Int. Pharmacodyn. Ther.245, 20–41.
  8. Lhoëst G. (1979): The proximo-distal carcinogen of the K region of benzo(a)pyrene in Mass Spectrometry in Biochemistry and Medicine, Frigerio A., Plenum Press and London,2, 179–190.
  9. Lhoëst G. (1980): 4-hydroxy-5-oxo-4,5-dihydrobenzo(a)-pyrene, a new metabolite of benzo(a)pyrene, Eur. J. of Drug Metabolism and Pharmacokinetics,5, 41–43.