User menu

Hepatic Peroxisomal Proliferation Caused By Ethyl 2[5(4-chloro-phenyl)pentyl]oxiran-2-carboxylate (cpoc) - a Hypoglycemic Inhibitor of Mitochondrial Fatty-acid Oxidation

Bibliographic reference Sherratt, HSA. ; Bartlett, K. ; Bone, AJ. ; Koundakjian, PP. ; Turnbull, DM. ; et. al. Hepatic Peroxisomal Proliferation Caused By Ethyl 2[5(4-chloro-phenyl)pentyl]oxiran-2-carboxylate (cpoc) - a Hypoglycemic Inhibitor of Mitochondrial Fatty-acid Oxidation. In: New York Academy of Sciences. Annals, Vol. 386, no. MAY, p. 446-448 (1982)
Permanent URL http://hdl.handle.net/2078.1/57113
  1. Wolf H., Diabetologia., 21, 344 (1981)
  2. Osmundsen H., Sherratt H.S.A., A Novel mechanism for inhibition of β-oxidation by methylenecyclopropylacetyl-CoA, a metabolite of hypoglycin, 10.1016/0014-5793(75)80951-3
  3. Osmundsen H, Bremer J, A spectrophotometric procedure for rapid and sensitive measurements of β-oxidation. Demonstration of factors that can be rate-limiting for β-oxidation, 10.1042/bj1640621
  4. Mannaerts Guy P., Thomas Josse, Debeer Luc J., McGarry J.Denis, Foster Daniel W., Hepatic fatty acid oxidation and ketogenesis after clofibrate treatment, 10.1016/0005-2760(78)90063-2
  5. SKREDE Sverre, HALVORSEN Ola, Increased Biosynthesis of CoA in the Liver of Rats Treated with Clofibrate, 10.1111/j.1432-1033.1979.tb13180.x
  6. Mackerer Carl R., Effect of sub-acute administration of clofibrate on the oxidation of fatty acids by liver mitochondria, 10.1016/0006-2952(77)90283-0
  7. Lazarow P. B., Science, 197, 580 (1977)
  8. Baudhuin P., Methods Enzymol., 32, 13 (1974)
  9. Neat C E, Osmundsen H, The rapid preparation of peroxisomes from rat liver by using a vertical rotor, 10.1042/bj1800445
  10. Lazarow P. B., De Duve C., A fatty acyl-CoA oxidizing system in rat liver peroxisomes; enhancement by clofibrate, a hypolipidemic drug., 10.1073/pnas.73.6.2043
  11. VAN HOOF FRANÇOIS, HUE LOUIS, SHERRATT H. STANLEY A., Protection of Rats Against Hypoglycin and Pent-4-enoate Toxicity by Pretreatment with Clofibrate, 10.1042/bst0070163
  12. Neat C E, Thomassen M S, Osmundsen H, Effects of high-fat diets on hepatic fatty acid oxidation in the rat Isolation of rat liver peroxisomes by vertical-rotor centrifugation by using a self-generated, iso-osmotic, Percoll gradient, 10.1042/bj1960149