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Invivo Metabolism of Dimethylformamide and Relationship To Toxicity in the Male-rat

Bibliographic reference Scailteur, V. ; Lauwerys, Robert. Invivo Metabolism of Dimethylformamide and Relationship To Toxicity in the Male-rat. In: Archives of Toxicology, Vol. 56, no. 2, p. 87-91 (1984)
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  1. Barnes JR, Henry NW (1974) The determination of N-methylformamide and N-methylacetamide in urine. Am Ind Hyg Assoc J: 84?87
  2. Brindley C, Gescher A, Harpur ES, Ross D, Slack JA, Threadgill MD, Whitby H (1982) Studies of the pharmacology of N-methylformamide in mice. Cancer Treat Rep 66: 1957?1965
  3. Ellman GL (1955) Tissue sulphydryl groups. Arch Biochem Biophys 82: 70?74
  4. Gescher A, Gibson NW, Hickman JA, Langdon SP, Ross D, Atassi G (1982) N-methylformamide: antitumour activity and metabolism in mice. Br J Cancer 45: 843?850
  5. Kimmerle G, Eben A (1975a) Metabolism studies of N,N-dimethylformamide. I. Studies in rats and dogs. Int Arch Arbeitsmed 34: 109?126
  6. Kimmerle G, Eben A (1975b) Metabolism studies of N,N-dimethylformamide. II. Studies in persons. Int Arch Arbeitsmed 34: 127?136
  7. Krivanek D, McLaughlin M, Fayerweather WE (1978) Monomethylformamide levels in human urine after repetitive exposure to dimethylformamide vapor. J Occup Med 20: 179?182
  8. Lauwerys R, Kivits A, Lhoir M, Rigolet P, Houbeau D, Buchet JP, Roels HA (1980) Biological surveillance of workers exposed to dimethylformamide and the influence of skin protection on its percutaneous absorption. Int Arch Occup Environ Health 45: 189?203
  9. Maxfield ME, Barnes JR, Azar A, Trochimowicz HT (1975) Urinary excretion of metabolite following experimental human exposure to dimethylformamide and dimethylacetamide. J Occup Med 17: 506?511
  10. Merkle J, Zeller H (1980) Untersuchungen von Acetamiden und Formamiden auf embryotoxische und teratogene Wirkung bei Kaninchen. Arzneim Forsch 30: 1557?1562
  11. Nash T (1953) The colorimetric estimation of formaldehyde by means of Hantzch reaction. Biochem J 55: 412?416
  12. Scailteur V, Buchet JP, Lauwerys R (1981) The relationship between dimethylformamide metabolism and toxicity. In: Brown SS, Davies DS (eds) Organ directed toxicity, chemical indices and mechanisms. Pergamon Press, Oxford New York, pp 169?174
  13. Scailteur V, de Hoffmann E, Buchet JP, Lauwerys R (1984) Study on in vivo and in vitro metabolism of dimethylformamide in male and female rats. Toxicology 29: 221?234
  14. Scailteur V, Lauwerys R (1984) In vivo and in vitro oxidative biotransformation of dimethylformamide in rat. Chem Biol Interact 50: 327?337
  15. Van Doorn R, Borm PJA, Leijdekkers CM, Henderson PTh, Reuvers J, Van Bergen TJ (1980) Detection and identification of S-methylcysteine in urine of workers exposed to methyl chloride. Int Arch Occup Environ Health 46: 99?109
  16. Waynforth HB (1980) Experimental and surgical technique in the rat. Academic Press, London New York
  17. Whitby H, Gescher A, Levy L (1984) An investigation of the mechanism of hepatotoxicity of the antitumour agent N-methylformamide in mice. Biochem Pharmacol 33: 295?302
  18. Yonemoto J, Suzuki S (1980) Relation of exposure to dimethylformamide vapor and the metabolite, methylformamide, in urine of workers. Int Arch Occup Environ Health 46: 159?165