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Ultrastructural-changes in the Respiratory-tract of Rats Following Methyl Isocyanate Inhalation

Bibliographic reference Dinsdale, D. ; Nemery, B. ; Sparrow, S.. Ultrastructural-changes in the Respiratory-tract of Rats Following Methyl Isocyanate Inhalation. In: Archives of Toxicology, Vol. 59, no. 6, p. 385-390 (1987)
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  1. Ahearn MJ, Lewis CW, Campbell LA, Luce JK (1967) Nuclear bleb formation in human bone marrow cells during cytosine arabinoside therapy. Nature 215: 196?197
  2. Clausen KP, von Haam E (1969) Fine structure of malignancy-associated changes (MAC) in peripheral human leukocytes. Acta CytoIl 13: 435?442
  3. Diller WF, Bruch J, Dehnen W (1985) Pulmonary changes in the rat following low phosgene exposure. Arch Toxicol 57: 184?190
  4. Dinsdale D, Verschoyle RD, Ingham JE (1984) Ultrastructural changes in rat Clara cells induced by a single dose of O,S,S-trimethyl phosphorodithioate. Arch Toxicol 56: 59?65
  5. Dinsdale D, Verschoyle RD (1987) Arch Toxicol, 27th EST Congress (in press)
  6. Duncan Burris, Scheel Lester D., Fairchild Edward J., Killens Richard, Graham Stuart, Toluene Diisocyanate Inhalation Toxicity: Pathology and Mortality, 10.1080/00028896209342899
  7. Evans MJ (1984) Oxidant gases. Environ Health Perspect 55: 85?95
  8. Evans MJ, Cabral-Anderson LJ, Freeman G (1978) Role of the Clara cell in renewal of the bronchiolar epithelium. Lab Invest 38: 648?655
  9. Evans MJ, Shami SG, Cabral-Anderson LJ, Dekker NP (1986) Role of nonciliated cells in renewal of the bronchial epithelium of rats exposed to NO2. Am J Pathol 123: 126?133
  10. Ferguson JS, Schaper M, Stock MF, Weyel DA, Alarie Y (1986) Sensory and pulmonary irritation with exposure to methyl isocyanate. Toxicol Appl Pharmacol 82: 329?335
  11. Fowler EH, Dodd DE (1986) Acute inhalation studies with methy-lisocyanate vapor. II. Respiratory tract changes in guinea pigs, rats and mice. Fund Appl Toxicol 6: 756?771
  12. Freeman G, Crane SC, Stephens RJ, Furiosi NJ (1968) Pathogenesis of the nitrogen dioxide-induced lesion in the rat lung: A review and presentation of new observations. Am Rev Respir Dis 98: 429?443
  13. Huehns ER, Lutzner M, Hecht F (1964) Nuclear abnormalities of the neutrophils in D1 (13?15-trisomy syndrome. Lancet i: 589?590
  14. Keenan KP, Combs JW, McDowell EM (1982) Regeneration of hamster tracheal epithelium after mechanical injury. I. Focal lesions: quantitative morphologic study of cell proliferation. Virchows Arch (Cell Pathol) 41: 193?214
  15. LEPKOWSKI WLL, BHOPAL, 10.1021/cen-v063n048.p018
  16. Luft JH (1971) Ruthenium red and violet. I. Chemistry, purification, methods of use for electron microscopy and mechanism of action. Anat Rec 171: 347?368
  17. Nemery B, Dinsdale D, Sparrow S, Ray DE (1985a) Effects of methyl isocyanate on the respiratory tract of rats. Br J Ind Med 42: 799?805
  18. Nemery B, Sparrow S, Dinsdale D (1985b) Methyl isocyanate: thiosulphate does not protect. Lancet ii: 1245?1246
  19. Salmon AG, Andersson N, Kerr Muir M (1985) Toxicity of methyl isocyanate: the current picture. Ind J Med Res 82 (suppl): 10?16
  20. Stalzer RC, Kiely JM, Pease GL, Brown AL (1965) Effect of 5-flu-orouracil on human hematopoiesis. Cancer 18: 1071?1078
  21. Stephens RJ, Freeman G, Crane SC, Furiosi NJ (1971) Ultrastructural changes in the terminal bronchiole of the rat during continuous, low-level exposure to nitrogen dioxide. Exp Mol Pathol 14: 1?19
  22. ten Berge WF (1985) The toxicity of methylisocyanate for rats. J Hazardous Materials 12: 309?311
  23. Winternitz MC, Smith GH, McNamara FP (1920) Epithelial proliferation following the intrabronchial insufflation of acid. J Exp Med 32: 205?217
  24. Zichner L, Engel D (1971) Electron microscopical examination of the ultra-sonic effect on the rabbit's synovial membrane. Z Ges Exp Med 154: 1?13