Authors |
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Document type |
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Article de périodique (Journal article) – Article de recherche
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Abstract |
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We report the case of a 41-year-old woman with a 5-year history of left-sided ulcerative colitis easily controlled by sulfasalazine. She was admitted because of severe anemia, in the absence of any exacerbation of the colitis. A Coombs-positive (IgG type) hemolytic anemia was diagnosed and high-dose corticosteroid therapy was started, which proved to be unsuccessful. A splenectomy was then performed but the hemolytic anemia failed to subside. The patient was subsequently treated with a corticosteroid-azathioprine association with a sustained favourable effect on the anemia. The prevalence and pathophysiology of hemolytic anemia in ulcerative colitis is reviewed and a specific therapeutic approach is proposed. |
Publication date |
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1991 |
Language |
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Anglais |
Journal information |
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"Acta Gastro-Enterologica Belgica (Multilingual Edition)" - Vol. 54, no. 1, p. 34-37 (1991) |
Peer reviewed |
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yes |
Publisher |
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Assoc Soc Scientifique Med Belges (Brussels)
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issn |
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0001-5644 |
Publication status |
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Publié |
Affiliation |
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UCL
- MD/MINT - Département de médecine interne
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Keywords |
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ULCERATIVE COLITIS ; HEMOLYTIC ANEMIA ; CORTICOSTEROIDS ; AZATHIOPRINE
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Links |
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