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Syntheses of New 4-trifluoromethylated 1,3-oxazin-6-ones From the Enamine of Ethyl Trifluoroacetoacetate

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Decockplancquaert, MA. Evariste, F. Guillot, N. Janousek, Z. Maliverney, C. Viehe, HG.

New 4-trifluoromethyl-1,3-oxazin-6-ones have been prepared in excellent yields from ethyl 3-amino-4.4.4-trifluorocrotonate (ATFC) by two original procedures: reaction of ATFC with phosgeniminium chlorides to give 2-dialkylamino-4-trifluoromethyl-1,3-oxazin-6-ones, or action of chlorinating agents on N-acyl ATFC. The reactivity of ATFC in these reactions is compared with non-fluorinated analogs.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1992
Language Anglais
Journal information "Societes Chimiques Belges. Bulletin" - Vol. 101, no. 4, p. 313-321 (1992)
Peer reviewed yes
Publisher Soc Chimique Belgique (Brussels)
issn 0037-9646
Publication status Publié
Affiliation UCL
Links
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Bibliographic reference Decockplancquaert, MA. ; Evariste, F. ; Guillot, N. ; Janousek, Z. ; Maliverney, C. ; et. al. Syntheses of New 4-trifluoromethylated 1,3-oxazin-6-ones From the Enamine of Ethyl Trifluoroacetoacetate. In: Societes Chimiques Belges. Bulletin, Vol. 101, no. 4, p. 313-321 (1992)
Permanent URL http://hdl.handle.net/2078.1/50443