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Rat-liver Microsomal Metabolism of 2-halogenated 4-methylanilines

Bibliographic reference Boeren, S. ; Tyrakowska, B. ; Vervoort, J. ; Dehoffman, E. ; Teunis, K. ; et. al. Rat-liver Microsomal Metabolism of 2-halogenated 4-methylanilines. In: Xenobiotica : the fate of foreign compounds in biological systems, Vol. 22, no. 12, p. 1403-1423 (1992)
Permanent URL http://hdl.handle.net/2078.1/49938
  1. Bamberger E, Annalen, 424, 233 (1921)
  2. Cashman John R., Hanzlik Robert P., Microsomal oxidation of thiobenzamide. A photometric assay for the flavin-containing monooxygenase, 10.1016/0006-291x(81)91881-7
  3. Cheever Kenneth L., Richards Donald E., Plotnick Harry B., Metabolism of ortho-, meta-, and para-toluidine in the adult male rat, 10.1016/0041-008x(80)90069-1
  4. Coutts R. T., Pound N. J., Preparation of an aromatic hydroxylamine and some cyclic hydroxamic acids, and their reaction with hydrochloric acid, 10.1139/v70-306
  5. Daly John W., Guroff Gordon, Udenfriend Sidney, Witkop Bernhard, Hydroxylation of alkyl and halogen substituted anilines and acetanilides by microsomal hydroxylases, 10.1016/0006-2952(68)90154-8
  6. Furst Arthur, Moore Richard E., Reductions with Hydrazine Hydrate Catalyzed by Raney Nickel. II. Aromatic Nitro Compounds to Intermediate Products1, 10.1021/ja01577a044
  7. Gorrod J. W., Gooderham N. J., Microsomal N- and C-oxidation of 4-substituted N-benzylanilines, 10.3109/00498258509049097
  8. Gorrod J. W., Manson D., The metabolism of aromatic amines, 10.3109/00498258609038975
  9. Hecht Stephen S., El-Bayoumy Karam, Tulley Lorraine, LaVoie Edmond, Structure-mutagenicity relationships of N-oxidized derivatives of aniline, o-toluidine, 2'-methyl-4-aminobiphenyl, and 3,2'-dimethyl-4-aminobiphenyl, 10.1021/jm00194a019
  10. Herr F., Naunyn-Schmiedebergs Archiv fuer experimentelle Pathologie und Pharmakologie, 235, 351 (1959)
  11. Holmes Richard R., Bayer Raymond P., A Simple Method for the Direct Oxidation of Aromatic Amines to Nitroso Compounds1, 10.1021/ja01498a054
  12. KENNEDY RICHARD J., STOCK ALBERT M., The Oxidation of Organic Substances by Potassium Peroxymonosulfate, 10.1021/jo01081a019
  13. Kiese M, Naunyn-Schmiedebergs Archiv fuer experimentelle Pathologie und Pharmakologie, 244, 387 (1963)
  14. Knowles Charles O., Sen Gupta Anil K., N’-(4-Chloro-o-tolyl)-N,N-Dimethylformamidine-14C (Galecron) and 4-Chloro-o-touidine-14C Metabolism in the White Rat1, 10.1093/jee/63.3.856
  15. Lal Bansi, Gidwani Ramesh M., Reden Jurgen, de Souza Noel J., Regiospecific oxidation by DDQ of unhindered alkyl groups in sterically hindered aromatic amines, 10.1016/s0040-4039(01)81321-6
  16. Lenk Werner, Riedl Michael, N-Hydroxy-N-arylacetamides. V. Differences in the Mechanism of Haemoglobin Oxidationin Vitro, byN-hydroxy-4-Chloroacetanilide andN-Hydroxy-4-Chloroaniline, 10.3109/00498258909042286
  17. Leslie Catherine, F. Reidy Gordon, Murray Michael, H. Stacey Neill, Induction of xenobiotic biotransformation by the insecticide chlordimeform, a metabolite 4-chloro-o-toluidine and a structurally related chemical o-toluidine, 10.1016/0006-2952(88)90242-0
  18. Rietjens Ivonne M. C. M., Vervoort Jacques, Microsomal metabolism of fluoroanilines, 10.3109/00498258909043181
  19. Schenker Erhard, Neuere Methoden der präparativen organischen Chemie IV Anwendung von komplexen Borhydriden und von Diboran in der organischen Chemie, 10.1002/ange.19610730302
  20. Soon Son Ock, Everett D. W., Fiala E. S., Metabolism ofo-[methyl-14C]toluidine in the F344 rat, 10.3109/00498258009033781
  21. Stavenuiter J.F.C., Verrips-Kroon M., Bos E.J., Westra J.G., Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites, 10.1093/carcin/6.1.13
  22. Vervoort J., De Jager P. A., Steenbergen J., Rietjens I. M. C. M., Development of a19F-n.m.r. method for studies on the invivoandin vitrometabolism of 2-fluoroaniline, 10.3109/00498259009046882
  23. Vogel A. I, Textbook of Practical Organic Chemistry (1989)
  24. Wade K. E., Bioanalysis of drugs and metabolites, 383 (1988)
  25. Weisburger E. K., Journal of Environmental Pathology and Toxicology, 2, 325 (1978)
  26. Weisburger J. H., Pharmacological Reviews, 25, 1 (1973)
  27. Yoshimi Naoki, Sugie Shigeyuki, Iwata Hitoshi, Niwa Kenji, Mori Hideki, Hashida Chise, Shimizu Hidesuke, The genotoxicity of a variety of aniline derivatives in a DNA repair test with primary cultured rat hepatocytes, 10.1016/0165-1218(88)90159-0
  28. Zimmer D., Mazurek J., Petzold G., Bhuyan B.K., Bacterial mutagenicity and mammalian cell DNA damage by several substituted anilines, 10.1016/0165-1218(80)90003-8