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The force-velocity relation of the rabbit inferior oblique muscle: influence of temperature

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Asmussen, G. Beckers-Bleukx, G. Maréchal, Georges [UCL]

The contractile properties of the rabbit inferior oblique muscle (IO) were studied in vitro with direct stimulation at temperatures between 20 and 35 degrees C. Isovelocity releases were used to determine the force/ velocity relation. Cooling the muscle from 35 degrees C to 20 degrees C increased contraction and half-relaxation times of single twitches with a temperature coefficient (Q(10)) of 0.4, but did not affect significantly the twitch tension. The tetanic tension increases with increasing temperature (Q(10) = 1.32). Cooling decreased the maximum shortening velocity of the IO with a Q(10) of 1.6 and the maximum mechanical power with a Q(10) of 2.3. At 35 degrees C, the maximum speed of shortening of the muscle (19 +/- 2 muscle lengths/s, mean+/-SEM) corresponded to a maximum shortening velocity of the sarcomeres of 57 +/- 6 mu m/s. This value is similar to data obtained for extraocular muscles (EOM) of smaller rodents (mice and rats). In comparison with mammalian limb muscles the isometric and force-velocity properties of mammalian EOM appear to be virtually independent of the size of the animal. Thus, IO is a fast-twitch muscle endowed with a maximum velocity of shortening higher than that of fast-twitch skeletal muscle, but using a tetanic mechanical power lower than that produced by slow-twitch muscle: the combination of these properties makes it ideally suited to move an ocular globe of low mass at high velocity.

Document type Article de périodique (Journal article) – Article de recherche
Access type Accès libre
Publication date 1994
Language Anglais
Journal information "Pflügers Archiv - European journal of physiology" - Vol. 426, no. 6, p. 542-547 (1994)
Peer reviewed yes
Publisher Springer
issn 0031-6768
e-issn 1432-2013
Publication status Publié
Affiliation UCL - MD/FSIO - Département de physiologie et pharmacologie
Keywords Extraocular muscle ; Inferior oblique muscle ; Force-velocity relation ; Temperature
Links
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Bibliographic reference Asmussen, G. ; Beckers-Bleukx, G. ; Maréchal, Georges. The force-velocity relation of the rabbit inferior oblique muscle: influence of temperature. In: Pflügers Archiv - European journal of physiology, Vol. 426, no. 6, p. 542-547 (1994)
Permanent URL http://hdl.handle.net/2078.1/49043