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Functionalized Hydantoins As Potential Antibiotics

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Marchand-Brynaert, Jacqueline [UCL] Amadei, E. Ghosez, Léon [UCL]

The 5-acylamino-3-acetylhydantoin derivatives 8 were designed as potential antibiotics mimicking lactivicin 1. The racemic compounds 19a-c, prepared in six steps from 5-oxohydantoin, were inactive onto bacterial tests.

Document type Article de périodique (Journal article) – Article de recherche
Publication date 1994
Language Anglais
Journal information "Societes Chimiques Belges. Bulletin" - Vol. 103, no. 5-6, p. 213-218 (1994)
Peer reviewed yes
Publisher Soc Chimique Belgique (Brussels)
issn 0037-9646
Publication status Publié
Affiliation UCL
Links
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Bibliographic reference Marchand-Brynaert, Jacqueline ; Amadei, E. ; Ghosez, Léon. Functionalized Hydantoins As Potential Antibiotics. In: Societes Chimiques Belges. Bulletin, Vol. 103, no. 5-6, p. 213-218 (1994)
Permanent URL http://hdl.handle.net/2078.1/48631