Dostal, J.
Taborska, E.
Slavik, J.
Potacek, M.
de Hoffmann, Edmond
[UCL]
The structure of chelerythrine free base was examined. When chelerythrine chloride [1b] was treated with aqueous K2CO3 solution, bis[6-(5,6-dihydrochelerythrinyl)] ether [3] was obtained. An excess of aqueous ammonia under the same conditions yielded bis[6-(5,6-dihydrochelerythrinyl)] amine [4]. The structures of both derivatives were determined by elemental analysis, ir, 1D and 2D nmr, eims, and cims. The formation of an unstable hydroxy adduce 2a (pseudobase) was observed in H-1-nmr experiments only.
| Bibliographic reference |
Dostal, J. ; Taborska, E. ; Slavik, J. ; Potacek, M. ; de Hoffmann, Edmond. Structure of Chelerythrine Base. In: Journal of Natural Products, Vol. 58, no. 5, p. 723-729 (1995) |
| Permanent URL |
http://hdl.handle.net/2078.1/47965 |
