Madani, A
Christophe, C.
Ferster, A.
Danloy, Bernard
[UCL]
Background. A 10-year-old boy with a history of acute lymphoblastic leukaemia (ALL), but without previous evidence of central nervous system involvement, presented with seizures 3 years after complete remission.
Materials and methods. MRI showed bilateral enlargement of the optic nerves despite normal ophthalmological examination.
Results. Only the third cerebrospinal fluid examination showed 2 % blasts without concomitant bone-marrow infiltration. Enlargement of the optic nerves was consistent with bilateral leukaemic peri-optic nerve infiltration. The appearances returned to normal after chemotherapy
Conclusion. The optic nerves are a potential site of relapse in patients with systemic and meningeal ALL, even in the absence of ophthalmological signs.
Bibliographic reference |
Madani, A ; Christophe, C. ; Ferster, A. ; Danloy, Bernard. Peri-optic nerve infiltration during leukaemic relapse: MRI diagnosis. In: Pediatric Radiology : roentgenology, nuclear medicine, ultrasonics, CT, MRI, Vol. 30, no. 1, p. 30-32 (2000) |
Permanent URL |
http://hdl.handle.net/2078.1/43758 |