Marko, Istvan
[UCL]
Declercq, Jean-Paul
[UCL]
Vanherck, JC.
Ates, Ali
[UCL]
Tinant, Bernard
[UCL]
Upon treatment with t BuOK/H2O, a variety of omega-halo-beta-keto-ketals undergo smooth cyclisation, affording in excellent yields mono-protected [n,m] spiro bicyclic diketones. This transformation is highly stereoselective producing, in all cases, the diastereoisomerically pure spiro derivatives. (C) 2003 Elsevier Science Ltd. All rights reserved.
Bibliographic reference |
Marko, Istvan ; Declercq, Jean-Paul ; Vanherck, JC. ; Ates, Ali ; Tinant, Bernard. Efficient and convergent stereocontrolled spiroannulation of ketones. In: Tetrahedron Letters, Vol. 44, no. 16, p. 3333-3336 (2003) |
Permanent URL |
http://hdl.handle.net/2078.1/41090 |