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Experimental and clinical radiofrequency ablation: Proposal for standardized description of coagulation size and geometry

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Mulier, Stefaan [MONT] Ni, Yicheng Frich, Lars Burdio, Fernando Denys, Alban L. Michel, Luc [UCL]

Background: Radiofrequency (RF) ablation is used to obtain local control of unresectable tumors in liver, kidney, prostate, and other organs. Accurate data on expected size and geometry of coagulation zones are essential for physicians to prevent collateral damage and local tumor recurrence. The aim of this study was to develop a standardized terminology to describe the size and geometry of these zones for experimental and clinical RF. Methods: In a first step, the essential geometric parameters to accurately describe the coagulation zones and the spatial relationship between the coagulation zones and the electrodes were defined. In a second step, standard terms were assigned to each parameter. Results: The proposed terms for single-electrode RF ablation include axial diameter, front margin, coagulation center, maximal and minimal radius, maximal and minimal transverse diameter, ellipticity index, and regularity index. In addition a subjective description of the general shape and regularity is recommended. Conclusions: Adoption of the proposed standardized description method may help to fill in the many gaps in our current knowledge of the size and geometry of RF coagulation zones.

Document type Article de périodique (Journal article) – Article de recherche – Journal Article
Access type Accès restreint
Publication date 2007
Language Anglais
Journal information "Annals of Surgical Oncology" - Vol. 14, no. 4, p. 1381-1396 (2007)
Peer reviewed yes
Publisher Springer New York LLC ((United States) New York)
issn 1068-9265
e-issn 1534-4681
Publication status Publié
Affiliations UCL - MD/RAIM - Département de radiologie et d'imagerie médicale
UCL - MD/CHIR - Département de chirurgie
UCL - (MGD) Service de chirurgie
UCL - (MGD) Service de radiologie - résonance magnétique
MESH Subject Liver Neoplasms - pathology - surgery ; Liver - pathology - surgery ; Humans ; Equipment Design ; Electrodes ; Catheter Ablation - standards ; Animals
Keywords radiofrequency ablation ; tumor ablation ; size ; geometry ; liver ; kidney
Links
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Bibliographic reference Mulier, Stefaan ; Ni, Yicheng ; Frich, Lars ; Burdio, Fernando ; Denys, Alban L. ; et. al. Experimental and clinical radiofrequency ablation: Proposal for standardized description of coagulation size and geometry. In: Annals of Surgical Oncology, Vol. 14, no. 4, p. 1381-1396 (2007)
Permanent URL http://hdl.handle.net/2078.1/38058